iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074873

UUCD1 version

UUC-OrC-00751

Ensembl Protein ID

ENSOCUP00000006290.2

UniProt Accession

G1SSQ5; G1SSQ5_RABIT

Protein Name

Uncharacterized protein

Gene Name

TRIM24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000007274.3	ENSOCUT00000007277.3	ENSOCUP00000006290.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.60e-09	37.8	711	755

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C+vC++gge    l++C+kC ++fH  C+ ++  +++p+ e wiC+ Cr
   Q: 711  DWCAVCQNGGE----LLCCDKCPKVFHLSCHVPT-LTNFPSGE-WICTFCR 755
           79*********....*******************.*******8.******8 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

VGVIRCPVCS QECAERHIID NFFVKDTTEV PSSTVEKSNQ VCTSCEDNAE ANGFCVECVE 60
WLCKTCIRAH QRVKFTKDHT VRQKEEVSPE AVGVTSQRPV FCPFHKKEQL KLYCETCDKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTGGAGTTA TCCGATGCCC AGTTTGCAGC CAGGAATGTG CTGAGAGACA TATCATAGAC 60
AATTTTTTCG TGAAGGACAC TACTGAGGTC CCCAGCAGCA CGGTCGAAAA GTCTAATCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR019786--Zinc_finger_PHD-type_CS
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box

PRINTS

PR00503--BROMODOMAIN

SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005719--C:nuclear euchromatin
GO:0005654--C:nucleoplasm
GO:0005726--C:perichromatin fibrils
GO:0003682--F:chromatin binding
GO:0034056--F:estrogen response element binding
GO:0004672--F:protein kinase activity
GO:0043565--F:sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0055074--P:calcium ion homeostasis
GO:0071391--P:cellular response to estrogen stimulus
GO:0008285--P:negative regulation of cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0046777--P:protein autophosphorylation
GO:0030163--P:protein catabolic process
GO:0042981--P:regulation of apoptotic process
GO:0031647--P:regulation of protein stability
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0070562--P:regulation of vitamin D receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001838	Ailuropoda melanoleuca	94.32	0.00e+00	1567.00
IUUC-Apl-003697	Anas platyrhynchos	79.64	0.00e+00	1308.00
IUUC-Bta-013282	Bos taurus	93.28	0.00e+00	1558.00
IUUC-Cja-018920	Callithrix jacchus	93.36	0.00e+00	1592.00
IUUC-Cfa-020984	Canis familiaris	94.43	0.00e+00	1580.00
IUUC-Cpo-022035	Cavia porcellus	92.51	0.00e+00	1608.00
IUUC-Csa-024208	Chlorocebus sabaeus	93.90	0.00e+00	1592.00
IUUC-Cin-025200	Ciona intestinalis	43.56	2.00e-42	167.00
IUUC-Dno-029145	Dasypus novemcinctus	93.58	0.00e+00	1627.00
IUUC-Dor-030396	Dipodomys ordii	90.68	0.00e+00	1231.00
IUUC-Ete-032414	Echinops telfairi	84.09	0.00e+00	904.00
IUUC-Eca-033489	Equus caballus	94.54	0.00e+00	1580.00
IUUC-Eeu-034654	Erinaceus europaeus	91.63	0.00e+00	752.00
IUUC-Fca-035844	Felis catus	90.71	0.00e+00	1453.00
IUUC-Fal-036735	Ficedula albicollis	79.72	0.00e+00	1316.00
IUUC-Gga-041124	Gallus gallus	79.42	0.00e+00	1288.00
IUUC-Ggo-044542	Gorilla gorilla	94.00	0.00e+00	1592.00
IUUC-Hsa-046785	Homo sapiens	93.90	0.00e+00	1590.00
IUUC-Hvu-047073	Hordeum vulgare	53.06	2.00e-12	68.90
IUUC-Itr-048262	Ictidomys tridecemlineatus	93.90	0.00e+00	1573.00
IUUC-Laf-054279	Loxodonta africana	92.09	0.00e+00	1586.00
IUUC-Mcc-055668	Macaca mulatta	94.00	0.00e+00	1593.00
IUUC-Meu-056195	Macropus eugenii	74.34	0.00e+00	802.00
IUUC-Mga-059272	Meleagris gallopavo	78.78	0.00e+00	1290.00
IUUC-Mmr-060936	Microcebus murinus	93.04	0.00e+00	1579.00
IUUC-Mdo-062848	Monodelphis domestica	89.46	0.00e+00	1488.00
IUUC-Mmu-063598	Mus musculus	92.30	0.00e+00	1538.00
IUUC-Mpu-066272	Mustela putorius furo	93.58	0.00e+00	1560.00
IUUC-Mlu-067958	Myotis lucifugus	91.99	0.00e+00	1569.00
IUUC-Nle-069375	Nomascus leucogenys	94.00	0.00e+00	1593.00
IUUC-Opr-070836	Ochotona princeps	82.52	0.00e+00	671.00
IUUC-Oan-073393	Ornithorhynchus anatinus	79.16	0.00e+00	1002.00
IUUC-Ogl-077865	Oryza glaberrima	51.02	7.00e-12	66.60
IUUC-Olo-080499	Oryza longistaminata	51.02	6.00e-12	67.40
IUUC-Opu-083209	Oryza punctata	51.02	7.00e-12	67.00
IUUC-Oga-088692	Otolemur garnettii	92.83	0.00e+00	1553.00
IUUC-Oar-090160	Ovis aries	94.00	0.00e+00	1568.00
IUUC-Ptr-090756	Pan troglodytes	93.90	0.00e+00	1590.00
IUUC-Pan-091719	Papio anubis	93.90	0.00e+00	1590.00
IUUC-Psi-093433	Pelodiscus sinensis	81.22	0.00e+00	1355.00
IUUC-Pab-098599	Pongo abelii	92.51	0.00e+00	1561.00
IUUC-Pca-100540	Procavia capensis	85.69	0.00e+00	954.00
IUUC-Pva-102478	Pteropus vampyrus	87.26	0.00e+00	1399.00
IUUC-Rno-105478	Rattus norvegicus	75.35	0.00e+00	635.00
IUUC-Sha-106740	Sarcophilus harrisii	83.51	0.00e+00	1390.00
IUUC-Sar-113615	Sorex araneus	91.71	0.00e+00	1373.00
IUUC-Ssc-115513	Sus scrofa	91.69	1.00e-142	498.00
IUUC-Tgu-117368	Taeniopygia guttata	79.00	0.00e+00	1306.00
IUUC-Tsy-118904	Tarsius syrichta	93.57	0.00e+00	1595.00
IUUC-Tae-124715	Triticum aestivum	51.02	5.00e-12	67.40
IUUC-Tbe-127354	Tupaia belangeri	81.30	0.00e+00	716.00
IUUC-Ttr-128983	Tursiops truncatus	88.51	0.00e+00	1160.00
IUUC-Vpa-130420	Vicugna pacos	92.28	0.00e+00	1542.00
IUUC-Vvi-131561	Vitis vinifera	49.06	7.00e-13	69.30

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence