iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118090

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Suppressor of cytokine signaling 1-like protein

Genbank Nucleotide ID

DQ643957

Gene Name

socs1; SOCS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000010558.1	ENSTRUT00000026757.1	ENSTRUP00000026649.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	43.12	8.00e-35	144.00	IUUC-Hsa-046010

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MVANGAVTDQ DKLRDQQPQD TPQSSQLQNW ATAGAKPTSA AISLYRTHFP TFSCQEDCNI 60
ITDTASKLER CGFYWGPLGV EDAHRMLRDA PLGSYLIRDS RQKDVFFTLS YHAKGGPVSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGCTGAAT CCGAGGGCTG CGAGGACAGC CGAGACCGGG TTCTGGATCC AAGCGTTGGG 60
GACGCCCGGA CCGGGAGACG ACCTTCGACC CGCCGCAGCA CTTAAAGACA AAACGGTACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity

KEGG

tru:100049621

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001204	Ailuropoda melanoleuca	36.88	3.00e-26	111.00
IUUC-Apl-003313	Anas platyrhynchos	42.16	7.00e-37	146.00
IUUC-Aca-005109	Anolis carolinensis	47.80	3.00e-36	144.00
IUUC-Ame-011550	Astyanax mexicanus	50.31	6.00e-47	180.00
IUUC-Bta-013411	Bos taurus	42.50	1.00e-35	142.00
IUUC-Cja-019595	Callithrix jacchus	43.12	4.00e-36	144.00
IUUC-Cfa-020563	Canis familiaris	43.75	2.00e-36	145.00
IUUC-Cpo-021374	Cavia porcellus	43.75	1.00e-36	146.00
IUUC-Csa-023333	Chlorocebus sabaeus	43.12	4.00e-36	144.00
IUUC-Dre-028507	Danio rerio	44.44	2.00e-44	171.00
IUUC-Dno-029406	Dasypus novemcinctus	43.12	2.00e-35	142.00
IUUC-Ete-032399	Echinops telfairi	41.88	2.00e-34	138.00
IUUC-Eca-033519	Equus caballus	41.25	5.00e-33	134.00
IUUC-Fal-036726	Ficedula albicollis	46.58	4.00e-37	147.00
IUUC-Gmo-039667	Gadus morhua	62.50	2.00e-36	145.00
IUUC-Gga-040970	Gallus gallus	41.43	2.00e-37	148.00
IUUC-Gac-041838	Gasterosteus aculeatus	68.45	4.00e-80	290.00
IUUC-Ggo-045569	Gorilla gorilla	43.12	2.00e-36	144.00
IUUC-Hsa-046010	Homo sapiens	43.12	4.00e-36	144.00
IUUC-Itr-047995	Ictidomys tridecemlineatus	43.12	6.00e-36	143.00
IUUC-Lch-050219	Latimeria chalumnae	48.45	7.00e-39	153.00
IUUC-Loc-052494	Lepisosteus oculatus	43.54	6.00e-42	163.00
IUUC-Laf-054219	Loxodonta africana	41.96	1.00e-27	115.00
IUUC-Mcc-054830	Macaca mulatta	43.12	4.00e-36	144.00
IUUC-Meu-056565	Macropus eugenii	43.12	4.00e-36	144.00
IUUC-Mga-060153	Meleagris gallopavo	46.58	2.00e-36	144.00
IUUC-Mmr-061365	Microcebus murinus	43.12	4.00e-36	144.00
IUUC-Mdo-062824	Monodelphis domestica	43.12	1.00e-35	142.00
IUUC-Mmu-064120	Mus musculus	42.50	5.00e-36	144.00
IUUC-Mpu-066839	Mustela putorius furo	43.12	4.00e-36	144.00
IUUC-Mlu-067829	Myotis lucifugus	43.75	2.00e-36	145.00
IUUC-Nle-069592	Nomascus leucogenys	41.88	2.00e-34	138.00
IUUC-Ont-072173	Oreochromis niloticus	67.58	7.00e-83	299.00
IUUC-Ocu-073996	Oryctolagus cuniculus	43.12	4.00e-36	144.00
IUUC-Ogl-077795	Oryza glaberrima	23.08	4.20e-02	32.30
IUUC-Ola-087158	Oryzias latipes	65.37	2.00e-76	278.00
IUUC-Oga-088076	Otolemur garnettii	45.00	1.00e-37	149.00
IUUC-Ptr-091241	Pan troglodytes	43.12	3.00e-36	144.00
IUUC-Pan-091836	Papio anubis	43.12	3.00e-36	144.00
IUUC-Psi-093628	Pelodiscus sinensis	39.32	7.00e-37	146.00
IUUC-Pfo-097501	Poecilia formosa	73.12	9.00e-78	282.00
IUUC-Pab-098170	Pongo abelii	43.12	4.00e-36	144.00
IUUC-Pva-102796	Pteropus vampyrus	42.50	1.00e-35	142.00
IUUC-Rno-105319	Rattus norvegicus	42.50	5.00e-36	144.00
IUUC-Sce-106417	Saccharomyces cerevisiae	30.43	5.30e+00	25.40
IUUC-Sha-107201	Sarcophilus harrisii	42.58	4.00e-34	137.00
IUUC-Ssc-116004	Sus scrofa	43.12	4.00e-36	144.00
IUUC-Tgu-116836	Taeniopygia guttata	40.19	6.00e-37	147.00
IUUC-Tni-120719	Tetraodon nigroviridis	71.36	3.00e-80	291.00
IUUC-Vpa-130235	Vicugna pacos	43.12	4.00e-36	144.00
IUUC-Xtr-132610	Xenopus tropicalis	42.45	1.00e-40	159.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence