iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000040265.1	ENSGALT00000046436.1	ENSGALP00000053066.1
ENSGALG00000040265.1	ENSGALT00000057064.1	ENSGALP00000055975.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-48	166.5	38	325

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ Ls++p++ + l e + +  +e+n+++++++l+ +l +l+++l     +++ + + + ll++l+ +  ++s++
   Q: 38   GLLNLGNTCFMNSLLQGLSSCPSFIRWLEEFTAQYKAEQNQPSEQQCLSLTLLHLLRALScqeVTEDDVLDASCLLEVLRIYRWQISTF 126
           9*****************************4444444556679999*************888889999********************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.........aeekkkkknkslisdlFqgqlksqikclecdnvs.sre 166
           e+qDa+E++++l ++le+e    ++ +++++++ ++ e++++         + + ++++n+   ++ F+g+l+s+++c++c+++s +r+
   Q: 127  EEQDAHELFHVLTSSLEDER--DRQPRVTHLFDVHSLEQPEItqkqiscrtRGSLPPMSNHWKSQHPFHGRLTSNMVCKHCEHQSpVRY 213
           *******************9..668888889999888888887777888777888889999**************************** PP
   S: 167  epfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkRfsfs 240
           ++f +lsl++p     ++ +l++cL++f + e++++   + c++c+               +k++ +k+lkl klP++L++hL+R s+s
   Q: 214  DTFDSLSLSIPAAMWGHPMTLDHCLHHFISSESVKD---VVCDNCTkiqaegtlngqsvenQKTTFVKQLKLGKLPQCLCIHLQRLSWS 299
           **********************************97...9******7777777777777777777***********************9 PP
   S: 241  eeqksrekinkkvefpleLdls..pfc 265
           ++ + + k +++v+f++ L ++  ++ 
   Q: 300  NQ-GTPLKRHEHVQFNEFLIMDiyKYH 325
           96.8889*********87655522444 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MRSWGVIGGL AAAVAAGIYV LWGPIAERKK RRRGLVPGLL NLGNTCFMNS LLQGLSSCPS 60
FIRWLEEFTA QYKAEQNQPS EQQCLSLTLL HLLRALSCQE VTEDDVLDAS CLLEVLRIYR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGGAGCT GGGGGGTGAT CGGGGGGCTG GCGGCCGCCG TGGCGGCGGG GATCTACGTG 60
CTGTGGGGGC CCATCGCCGA GAGGAAGAAG CGGAGGAGAG GTAGGGAGCG GCGGGGGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001733	Ailuropoda melanoleuca	76.52	3.00e-155	541.00
IUUC-Atr-002510	Amborella trichopoda	26.85	2.00e-13	70.90
IUUC-Apl-003645	Anas platyrhynchos	92.47	8.00e-104	369.00
IUUC-Ath-007622	Arabidopsis thaliana	30.96	4.00e-19	89.00
IUUC-Ame-010896	Astyanax mexicanus	61.60	1.00e-122	432.00
IUUC-Bta-012321	Bos taurus	76.38	8.00e-156	543.00
IUUC-Cel-018308	Caenorhabditis elegans	27.49	3.00e-28	119.00
IUUC-Cja-018826	Callithrix jacchus	74.56	8.00e-159	553.00
IUUC-Cfa-021206	Canis familiaris	78.01	2.00e-157	548.00
IUUC-Cpo-021343	Cavia porcellus	77.45	3.00e-156	545.00
IUUC-Csa-023419	Chlorocebus sabaeus	74.69	1.00e-159	555.00
IUUC-Cho-024475	Choloepus hoffmanni	74.09	6.00e-81	294.00
IUUC-Cne-027061	Cryptococcus neoformans	28.87	2.00e-12	67.40
IUUC-Dre-027563	Danio rerio	59.43	6.00e-121	427.00
IUUC-Dno-029929	Dasypus novemcinctus	77.57	1.00e-159	555.00
IUUC-Dor-030166	Dipodomys ordii	63.66	6.00e-120	424.00
IUUC-Dme-031627	Drosophila melanogaster	36.81	1.00e-22	100.00
IUUC-Ete-032634	Echinops telfairi	70.93	6.00e-145	507.00
IUUC-Eca-033968	Equus caballus	77.93	1.00e-157	549.00
IUUC-Eeu-035279	Erinaceus europaeus	70.99	2.00e-50	192.00
IUUC-Fca-036525	Felis catus	77.57	7.00e-164	570.00
IUUC-Fal-036606	Ficedula albicollis	86.58	0.00e+00	655.00
IUUC-Gmo-038726	Gadus morhua	64.42	1.00e-114	406.00
IUUC-Gac-042645	Gasterosteus aculeatus	57.14	6.00e-120	424.00
IUUC-Gma-042890	Glycine max	26.06	3.00e-15	76.60
IUUC-Ggo-045021	Gorilla gorilla	74.94	4.00e-160	557.00
IUUC-Hsa-045832	Homo sapiens	74.94	4.00e-160	557.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	77.13	2.00e-156	545.00
IUUC-Lch-050662	Latimeria chalumnae	73.74	1.00e-146	512.00
IUUC-Lpe-051078	Leersia perrieri	26.57	5.00e-19	89.00
IUUC-Loc-052611	Lepisosteus oculatus	66.67	4.00e-141	494.00
IUUC-Laf-053752	Loxodonta africana	76.72	1.00e-154	539.00
IUUC-Mcc-054892	Macaca mulatta	74.94	4.00e-160	557.00
IUUC-Meu-056673	Macropus eugenii	67.12	8.00e-108	383.00
IUUC-Mor-057143	Magnaporthe oryzae	20.97	3.00e-06	47.00
IUUC-Mtr-057976	Medicago truncatula	25.67	4.00e-22	99.40
IUUC-Mla-058970	Melampsora laricipopulina	21.36	7.00e-11	62.00
IUUC-Mga-059543	Meleagris gallopavo	97.51	0.00e+00	703.00
IUUC-Mmr-061534	Microcebus murinus	77.51	4.00e-161	561.00
IUUC-Mdo-062140	Monodelphis domestica	61.64	8.00e-117	413.00
IUUC-Mmu-063673	Mus musculus	74.33	2.00e-153	535.00
IUUC-Mpu-066328	Mustela putorius furo	77.51	1.00e-156	545.00
IUUC-Mlu-067938	Myotis lucifugus	77.57	6.00e-164	570.00
IUUC-Nle-069426	Nomascus leucogenys	74.08	2.00e-145	508.00
IUUC-Opr-070796	Ochotona princeps	81.90	4.00e-50	192.00
IUUC-Ont-072248	Oreochromis niloticus	61.52	6.00e-129	454.00
IUUC-Oan-072916	Ornithorhynchus anatinus	74.68	4.00e-165	574.00
IUUC-Ocu-074459	Oryctolagus cuniculus	82.77	1.00e-118	419.00
IUUC-Oba-075765	Oryza barthii	26.43	1.00e-18	87.80
IUUC-Obr-076005	Oryza brachyantha	27.91	2.00e-17	84.00
IUUC-Ogl-077916	Oryza glaberrima	27.32	5.00e-21	95.50
IUUC-Ogu-078263	Oryza glumaepatula	26.43	6.00e-19	89.00
IUUC-Ome-081928	Oryza meridionalis	25.54	3.00e-18	86.30
IUUC-Oni-082424	Oryza nivara	26.43	6.00e-19	88.60
IUUC-Oru-085117	Oryza rufipogon	26.43	6.00e-19	88.60
IUUC-Ola-087429	Oryzias latipes	56.63	1.00e-116	412.00
IUUC-Oga-087981	Otolemur garnettii	77.39	2.00e-160	558.00
IUUC-Oar-089927	Ovis aries	76.64	2.00e-156	545.00
IUUC-Ptr-090878	Pan troglodytes	74.94	4.00e-160	557.00
IUUC-Pan-092698	Papio anubis	74.94	4.00e-160	557.00
IUUC-Psi-093451	Pelodiscus sinensis	81.70	5.00e-176	610.00
IUUC-Ppa-096015	Physcomitrella patens	21.95	2.00e-12	67.80
IUUC-Pfo-096096	Poecilia formosa	59.48	2.00e-123	435.00
IUUC-Pab-098676	Pongo abelii	73.68	9.00e-156	543.00
IUUC-Pca-100418	Procavia capensis	83.72	5.00e-112	397.00
IUUC-Ppe-101898	Prunus persica	25.37	5.00e-17	82.40
IUUC-Pva-103018	Pteropus vampyrus	74.28	2.00e-150	525.00
IUUC-Rno-105708	Rattus norvegicus	74.60	3.00e-152	531.00
IUUC-Sha-106971	Sarcophilus harrisii	74.50	6.00e-162	563.00
IUUC-Sit-110442	Setaria italica	28.16	4.00e-17	82.40
IUUC-Ssc-116397	Sus scrofa	77.19	4.00e-157	547.00
IUUC-Tgu-117446	Taeniopygia guttata	84.47	5.00e-179	620.00
IUUC-Tru-118268	Takifugu rubripes	58.31	2.00e-110	392.00
IUUC-Tsy-119484	Tarsius syrichta	75.90	1.00e-25	111.00
IUUC-Tni-119735	Tetraodon nigroviridis	52.96	2.00e-93	336.00
IUUC-Tca-121660	Theobroma cacao	26.15	1.00e-20	94.40
IUUC-Tae-125383	Triticum aestivum	27.94	4.00e-17	82.80
IUUC-Tur-126458	Triticum urartu	27.94	3.00e-17	82.80
IUUC-Tbe-127740	Tupaia belangeri	68.88	5.00e-134	470.00
IUUC-Ttr-129273	Tursiops truncatus	75.00	4.00e-150	524.00
IUUC-Vvi-131177	Vitis vinifera	26.55	6.00e-21	95.10
IUUC-Xtr-132374	Xenopus tropicalis	69.04	2.00e-141	495.00
IUUC-Xma-133267	Xiphophorus maculatus	60.20	4.00e-124	437.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence