iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048850

Ensembl Protein ID

ENSSTOP00000003868.2

UniProt Accession

I3M401; I3M401_ICTTR

Genbank Protein ID

ENSSTOP00000003868

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01066702

Gene Name

UBXN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000004310.2	ENSSTOT00000004309.2	ENSSTOP00000003868.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	4.90e-09	36.0	4	42
ULD/UDP/UFD/UBX	3.70e-20	72.3	210	291

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
             +le l+eMGF+r +a +aL+ + n  +eaA+++L+++
   Q: 4    LTALESLIEMGFPRGRAEKALALTgNQGIEAAMDWLMEH 42
           5689********************************987 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve....yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllv 79
           +++q+++q+RlpdG  l+++F+++++l +++ +ve    ++ +  +dp +L+s+fPrr +++ ++++ lqe+gLvps++l+v
   Q: 210  EYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVElhrgEEPGGGQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIV 291
           578*****************************************************************************98 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MAELTALESL IEMGFPRGRA EKALALTGNQ GIEAAMDWLM EHEDDPDVDE PLETPLGHVL 60
GREPTPSEQV GPEGPGTAAG ESKPVLTEEE RQEQTKRMLE LVAQKQRERE EREEREALER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCCTTCTT GCCACATCAG GTCCCCGCGG AAGCGGCGGC GGCGGCGGCG GCATGGCGGA 60
GCTGACGGCT CTGGAGAGTC TCATCGAGAT GGGCTTCCCC AGGGGACGCG CGTAAGGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50030--UBA
PS50033--UBX

Pfam

PF00627--UBA
PF00789--UBX

SMART

SM00165--UBA
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0000502--C:proteasome complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1904293--P:negative regulation of ERAD pathway
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903094--P:negative regulation of protein K48-linked deubiquitination
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000157--P:negative regulation of ubiquitin-specific protease activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001103	Aegilops tauschii	38.75	2.00e-09	56.60
IUUC-Aml-002325	Ailuropoda melanoleuca	94.56	3.00e-112	397.00
IUUC-Aca-004329	Anolis carolinensis	71.35	6.00e-50	189.00
IUUC-Aly-005639	Arabidopsis lyrata	35.19	2.00e-12	66.60
IUUC-Ath-006887	Arabidopsis thaliana	42.86	8.00e-12	64.70
IUUC-Ago-007989	Ashbya gossypii	37.18	6.00e-07	47.80
IUUC-Ame-011399	Astyanax mexicanus	55.05	8.00e-66	243.00
IUUC-Bta-013151	Bos taurus	94.59	3.00e-127	447.00
IUUC-Bdi-014311	Brachypodium distachyon	54.55	8.00e-10	58.20
IUUC-Bol-016537	Brassica oleracea	50.91	1.00e-11	64.30
IUUC-Bra-017906	Brassica rapa	59.09	2.00e-11	63.90
IUUC-Cel-018300	Caenorhabditis elegans	34.85	5.00e-13	67.80
IUUC-Cja-019084	Callithrix jacchus	94.72	2.00e-103	368.00
IUUC-Cfa-020997	Canis familiaris	91.55	4.00e-91	327.00
IUUC-Cpo-021736	Cavia porcellus	82.15	1.00e-85	308.00
IUUC-Csa-024040	Chlorocebus sabaeus	95.29	3.00e-104	370.00
IUUC-Cho-024543	Choloepus hoffmanni	96.06	7.00e-74	269.00
IUUC-Cin-025719	Ciona intestinalis	40.68	1.00e-41	162.00
IUUC-Csv-025854	Ciona savignyi	39.00	1.00e-40	159.00
IUUC-Cme-027235	Cyanidioschyzon merolae	47.73	3.00e-08	52.80
IUUC-Dre-027745	Danio rerio	53.51	6.00e-62	230.00
IUUC-Dno-029598	Dasypus novemcinctus	92.26	9.00e-105	372.00
IUUC-Dor-030917	Dipodomys ordii	83.80	9.00e-93	332.00
IUUC-Dme-032055	Drosophila melanogaster	42.53	4.00e-25	108.00
IUUC-Ete-032960	Echinops telfairi	76.24	2.00e-78	285.00
IUUC-Eca-034294	Equus caballus	94.61	2.00e-114	404.00
IUUC-Eeu-034906	Erinaceus europaeus	90.18	9.00e-107	379.00
IUUC-Fca-035653	Felis catus	92.96	1.00e-96	345.00
IUUC-Gmo-038755	Gadus morhua	50.64	5.00e-59	220.00
IUUC-Gac-042481	Gasterosteus aculeatus	54.84	3.00e-57	214.00
IUUC-Gma-042684	Glycine max	52.27	2.00e-10	60.50
IUUC-Ggo-044821	Gorilla gorilla	94.37	1.00e-97	349.00
IUUC-Hsa-046797	Homo sapiens	94.61	8.00e-106	376.00
IUUC-Lch-049508	Latimeria chalumnae	53.68	2.00e-57	215.00
IUUC-Laf-053932	Loxodonta africana	94.28	1.00e-131	462.00
IUUC-Mcc-055300	Macaca mulatta	95.62	3.00e-104	370.00
IUUC-Mtr-058774	Medicago truncatula	50.00	5.00e-10	57.80
IUUC-Mvi-060245	Microbotryum violaceum	40.48	7.00e-12	64.30
IUUC-Mmr-060979	Microcebus murinus	92.59	1.00e-108	385.00
IUUC-Mdo-062299	Monodelphis domestica	85.21	7.00e-97	346.00
IUUC-Mmu-063212	Mus musculus	95.96	2.00e-121	428.00
IUUC-Mac-065072	Musa acuminata	60.53	8.00e-11	60.80
IUUC-Mpu-066540	Mustela putorius furo	94.61	3.00e-114	404.00
IUUC-Mlu-067589	Myotis lucifugus	93.60	1.00e-108	385.00
IUUC-Nle-069045	Nomascus leucogenys	93.28	1.00e-77	281.00
IUUC-Opr-070772	Ochotona princeps	89.40	2.00e-91	328.00
IUUC-Ont-072006	Oreochromis niloticus	55.24	1.00e-57	216.00
IUUC-Oan-073244	Ornithorhynchus anatinus	63.21	1.00e-48	186.00
IUUC-Ocu-074333	Oryctolagus cuniculus	93.94	4.00e-106	377.00
IUUC-Oba-075451	Oryza barthii	49.06	5.00e-11	61.60
IUUC-Obr-076923	Oryza brachyantha	55.10	1.00e-11	63.90
IUUC-Ogl-077259	Oryza glaberrima	29.37	1.00e-10	60.80
IUUC-Ogu-078589	Oryza glumaepatula	49.06	5.00e-11	61.60
IUUC-Oin-079151	Oryza indica	49.06	5.00e-11	62.00
IUUC-Olo-080934	Oryza longistaminata	54.35	1.00e-10	60.10
IUUC-Ome-081253	Oryza meridionalis	49.06	5.00e-11	62.00
IUUC-Oni-082110	Oryza nivara	39.08	9.00e-11	60.80
IUUC-Opu-083336	Oryza punctata	49.06	6.00e-11	61.60
IUUC-Oru-085235	Oryza rufipogon	49.06	5.00e-11	61.60
IUUC-Osa-085611	Oryza sativa	49.06	5.00e-11	61.60
IUUC-Ola-086781	Oryzias latipes	54.98	2.00e-54	206.00
IUUC-Oga-088429	Otolemur garnettii	94.61	9.00e-106	375.00
IUUC-Oar-089885	Ovis aries	94.26	3.00e-127	447.00
IUUC-Ptr-091315	Pan troglodytes	94.01	2.00e-97	348.00
IUUC-Pan-092885	Papio anubis	95.29	3.00e-104	370.00
IUUC-Psi-093299	Pelodiscus sinensis	72.95	1.00e-66	246.00
IUUC-Pma-094221	Petromyzon marinus	64.37	2.00e-28	117.00
IUUC-Ppa-095484	Physcomitrella patens	51.11	2.00e-10	60.10
IUUC-Pfo-096188	Poecilia formosa	55.37	7.00e-56	210.00
IUUC-Pab-097881	Pongo abelii	89.23	1.00e-102	365.00
IUUC-Pop-098863	Populus trichocarpa	38.22	5.00e-12	65.50
IUUC-Pca-100977	Procavia capensis	91.29	9.00e-107	379.00
IUUC-Ppe-101243	Prunus persica	47.06	5.00e-10	58.20
IUUC-Pva-102169	Pteropus vampyrus	95.07	4.00e-101	360.00
IUUC-Rno-105459	Rattus norvegicus	95.29	4.00e-121	427.00
IUUC-Sha-107526	Sarcophilus harrisii	86.53	1.00e-97	348.00
IUUC-Ssl-108389	Sclerotinia sclerotiorum	26.67	2.00e-06	46.60
IUUC-Sit-110434	Setaria italica	31.35	2.00e-10	59.70
IUUC-Sly-111766	Solanum lycopersicum	45.90	1.00e-10	60.80
IUUC-Stu-112122	Solanum tuberosum	45.90	1.00e-10	60.80
IUUC-Sar-112945	Sorex araneus	93.51	2.00e-72	265.00
IUUC-Sbi-114159	Sorghum bicolor	31.89	2.00e-12	65.90
IUUC-Ssc-116114	Sus scrofa	95.29	2.00e-102	364.00
IUUC-Tru-117839	Takifugu rubripes	53.99	7.00e-58	217.00
IUUC-Tsy-118813	Tarsius syrichta	71.83	2.00e-99	355.00
IUUC-Tni-120504	Tetraodon nigroviridis	56.52	1.00e-58	219.00
IUUC-Tae-124974	Triticum aestivum	38.75	2.00e-09	56.20
IUUC-Tur-126615	Triticum urartu	38.75	2.00e-09	56.20
IUUC-Tbe-128034	Tupaia belangeri	94.72	3.00e-106	377.00
IUUC-Ttr-128468	Tursiops truncatus	89.86	7.00e-107	379.00
IUUC-Uma-129569	Ustilago maydis	34.62	1.00e-05	43.50
IUUC-Vpa-130179	Vicugna pacos	88.74	2.00e-78	285.00
IUUC-Vvi-131064	Vitis vinifera	44.78	2.00e-10	59.70
IUUC-Xtr-132119	Xenopus tropicalis	63.09	9.00e-69	253.00
IUUC-Xma-134067	Xiphophorus maculatus	54.55	6.00e-56	210.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence