iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-058709

Ensembl Protein ID

AES92720

UniProt Accession

G7JKJ3; A0A0C3X8Z6; G7JKJ3_MEDTR

Genbank Protein ID

AES92720.2

Protein Name

E3 ubiquitin-protein ligase UPL5-like protein

Genbank Nucleotide ID

CM001220

Gene Name

MTR_4g133120

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_4g133120	AES92720	AES92720

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	7.80e-91	306.4	542	873
ULD/UDP/UBQ/UBQ_Other	9.00e-10	39.7	96	154

Active Site

Position(s)	Description	Evidence
847	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllgk 103
           ++l++ l++ef++Ee+++  Gv re++ l++++l+n++  lf+  ++d++ + pn++s+++++ hl++F f Gr++++al+++  + + + ++f+ +l gk
   Q: 542  ESLRAGLFMEFKNEEATGP-GVLREWFLLVCQALFNQEHALFVACPKDRTRFLPNSASKVQHNLHLEYFSFCGRVIALALMHKVQVGIVFDRVFFLQLAGK 641
           678899************9.********************************************************************************* PP
   S: 104  klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviple 204
           +++led+ + dp+ly+s k+i++++++ i+  +l ltf ++ e+lg++k+ +L+pgG+ni V+ +N+ +Yv+l+++ r+ ++i+eqv +f +Gf e+++ +
   Q: 642  PITLEDIRDADPDLYRSCKQILDMDSDFIDSDALGLTFIREVEELGQRKAIQLCPGGKNIVVNSKNRVKYVDLLIKDRFVTSIAEQVSHFAKGFAEILSSS 742
           ************************9999*********************************************************************9999 PP
   S: 205  llslF.....teeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasddrlP 299
           +l+ F     + e+l+ ++ G+ + i+ved+k++t+y+ gyt+++ +i wFwe++ ++++ee+k +L F+T+ + lP++Gf+ l  rl +++  +s drlP
   Q: 743  KLQQFffqslESEDLDWMLRGSeDAISVEDWKAHTEYN-GYTDTDIQISWFWEIVGRMTAEEKKVLLFFWTSVKYLPVEGFRGLGSRLHIYKSHESGDRLP 842
           987654444478999*******999************5.5***********************************************9999999999**** PP
   S: 300  ssnTCfnyLkLPeYsskeilkekLlyAieet 330
           ss+TCf++L+ P Yss+ +++ +L + ++e 
   Q: 843  SSHTCFYRLCFPAYSSMPVMQARLKVITQEH 873
           ************************9877775 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   kvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekks 74
           +  p +tV+ + e+ie+ +gip  +qrLi+ Gk L+  +tL ++g++++  +hl+ +++
   Q: 96   HAYPEETVKSIHERIEEMKGIPLFEQRLIFNGKQLQWEQTLVECGIQNDANLHLVGRMR 154
           456889*****************************9999****************9986 PP

Organism

Medicago truncatula

Protein Sequence
(Fasta)

MTPIESPNLL QQQQQQNRSS SKRKLDEDDE NNALDDDLVY VRMRKDETTK TTLHSSWTGG 60
GGGSSGGDGG GAFSKKKSPI HFFIRMMSKG YNVVIHAYPE ETVKSIHERI EEMKGIPLFE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTCCGA TCGAAAGCCC TAACCTTCTT CAACAACAAC AACAACAGAA TCGTTCTTCG 60
TCCAAACGAA AATTAGACGA AGACGACGAA AACAACGCGT TAGATGATGA CTTAGTCTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR019956--Ubiquitin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50237--HECT
PS50053--UBIQUITIN_2

Pfam

PF00632--HECT
PF00240--ubiquitin

PRINTS

PR00348--UBIQUITIN

SMART

SM00119--HECTc
SM00213--UBQ

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

mtr:MTR_4g133120

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000327	Aegilops tauschii	43.07	1.00e-157	549.00
IUUC-Atr-002891	Amborella trichopoda	42.77	0.00e+00	665.00
IUUC-Aly-005570	Arabidopsis lyrata	49.81	0.00e+00	766.00
IUUC-Ath-007126	Arabidopsis thaliana	49.19	0.00e+00	764.00
IUUC-Bdi-014613	Brachypodium distachyon	41.48	9.00e-172	596.00
IUUC-Bol-016237	Brassica oleracea	47.52	0.00e+00	728.00
IUUC-Bra-017376	Brassica rapa	47.39	0.00e+00	726.00
IUUC-Gma-043337	Glycine max	70.02	0.00e+00	1217.00
IUUC-Hvu-047734	Hordeum vulgare	43.55	8.00e-171	593.00
IUUC-Lpe-051617	Leersia perrieri	43.43	2.00e-160	558.00
IUUC-Mac-065415	Musa acuminata	44.11	0.00e+00	632.00
IUUC-Oba-075190	Oryza barthii	45.58	7.00e-146	510.00
IUUC-Obr-076197	Oryza brachyantha	42.59	1.00e-160	559.00
IUUC-Ogl-077892	Oryza glaberrima	41.28	4.00e-143	501.00
IUUC-Ogu-078711	Oryza glumaepatula	42.18	1.00e-149	523.00
IUUC-Oin-079504	Oryza indica	41.40	6.00e-148	517.00
IUUC-Olo-080730	Oryza longistaminata	45.43	1.00e-145	509.00
IUUC-Ome-081851	Oryza meridionalis	42.49	5.00e-154	538.00
IUUC-Oni-082230	Oryza nivara	42.18	1.00e-149	523.00
IUUC-Opu-084015	Oryza punctata	42.95	4.00e-149	521.00
IUUC-Oru-084327	Oryza rufipogon	42.18	1.00e-149	523.00
IUUC-Osa-086148	Oryza sativa	41.16	1.00e-143	503.00
IUUC-Ppa-095337	Physcomitrella patens	40.47	0.00e+00	657.00
IUUC-Pop-099556	Populus trichocarpa	50.39	0.00e+00	841.00
IUUC-Ppe-101443	Prunus persica	60.30	0.00e+00	1029.00
IUUC-Smo-108789	Selaginella moellendorffii	42.04	0.00e+00	629.00
IUUC-Sit-110651	Setaria italica	43.46	3.00e-169	588.00
IUUC-Sly-111513	Solanum lycopersicum	56.67	0.00e+00	932.00
IUUC-Stu-112582	Solanum tuberosum	57.83	0.00e+00	941.00
IUUC-Sbi-114659	Sorghum bicolor	39.97	2.00e-125	442.00
IUUC-Tca-121392	Theobroma cacao	61.72	0.00e+00	1019.00
IUUC-Tae-125860	Triticum aestivum	38.95	6.00e-143	500.00
IUUC-Tur-126774	Triticum urartu	45.99	3.00e-159	555.00
IUUC-Vvi-131149	Vitis vinifera	58.23	0.00e+00	970.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence