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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Ath-007088
UUCD1 version UUC-ArT-01676
Ensembl Protein ID AT3G54130.1
UniProt Accession Q9M391; Q53XG9; ATX3H_ARATH
Genbank Protein ID CAB70987.1; AEE79191.1; AAR23732.1; AAR24770.1
Protein Name Ataxin-3 homolog; MJD1a-like; Machado-Joseph disease-like protein
Genbank Nucleotide ID AL132957; CP002686; BT010762; BT010992
Gene Name At3g54130; F24B22.90
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT3G54130 AT3G54130.1 AT3G54130.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
Protein-protein Interaction
HINTMentha
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
DUB/Josephin 44.64 3.00e-39 159.00 IUUC-Mmu-063600
UBD/Alpha-Helix/UIM 44.64 3.00e-39 159.00 IUUC-Mmu-063600
Active Site
Position(s) Description Evidence
20 Nucleophile ECO:0000255|PROSITE-ProRule:PRU00331}
126 Proton acceptor ECO:0000255|PROSITE-ProRule:PRU00331}
141 N/A {ECO:0000255|PROSITE-ProRule:PRU00331}
Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description


     Interacts with key regulators of transcription and represses transcription. Acts as a histone-binding protein that regulates transcription. Acts as a deubiquitinating enzyme (By similarity).
 Interacts with key regulators of transcription and represses transcription. Acts as a histone-binding protein that regulates transcription. Acts as a deubiquitinating enzyme (By similarity).
Protein Sequence
(Fasta)
MERTSNGGML YHEVQESNLC AVHCVNTVLQ GPFFSEFDLA AVAADLDGKE RQVMLEGAAV 60
GGFAPGDFLA EESHNVSLGG DFSIQVLQKA LEVWDLQVIP LNCPDAEPAQ IDPELESAFI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ath-007088|DUB,Josephin;UBD,UIM|Arabidopsis thaliana
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTAAATAATC TGTTAACTTG CTTCTTCTTC TTCTTTCTTC ATCTTCATCT TCATCTTCGC 60
TTCACAATCT CTTTGAGACT TTTGCATCGG AGCAATAATA ATATATTCAT CGCAAAATCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ath-007088|DUB,Josephin;UBD,UIM|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0539--Nucleus
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0833--Ubl conjugation pathway
Interpro

IPR033865--Ataxin-3
IPR006155--Josephin
IPR009068--S15_NS1_RNA-bd
PROSITE

PS50957--JOSEPHIN
Pfam

PF02099--Josephin
SMART

SM01246--Josephin
Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
KEGG ath:AT3G54130
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002015 Ailuropoda melanoleuca 44.79 5.00e-39 154.00
IUUC-Atr-002735 Amborella trichopoda 84.21 6.00e-19 84.30
IUUC-Apl-003210 Anas platyrhynchos 44.79 1.00e-38 152.00
IUUC-Aca-005171 Anolis carolinensis 35.40 1.00e-27 115.00
IUUC-Aly-005625 Arabidopsis lyrata 93.99 7.00e-130 455.00
IUUC-Ame-010715 Astyanax mexicanus 43.18 7.00e-40 157.00
IUUC-Bta-013538 Bos taurus 36.33 1.00e-39 156.00
IUUC-Bdi-015000 Brachypodium distachyon 63.92 4.00e-83 300.00
IUUC-Bol-015894 Brassica oleracea 86.93 8.00e-120 423.00
IUUC-Bra-018020 Brassica rapa 85.31 2.00e-113 401.00
IUUC-Cel-018121 Caenorhabditis elegans 34.32 6.00e-27 114.00
IUUC-Cja-018840 Callithrix jacchus 36.86 6.00e-41 160.00
IUUC-Cfa-021035 Canis familiaris 36.86 3.00e-41 161.00
IUUC-Cpo-021776 Cavia porcellus 44.51 8.00e-38 150.00
IUUC-Csa-023257 Chlorocebus sabaeus 35.66 2.00e-38 152.00
IUUC-Cho-024878 Choloepus hoffmanni 37.07 1.00e-37 149.00
IUUC-Cme-027158 Cyanidioschyzon merolae 31.51 3.00e-12 64.30
IUUC-Dre-027506 Danio rerio 35.08 1.00e-28 119.00
IUUC-Dno-029172 Dasypus novemcinctus 44.38 4.00e-39 154.00
IUUC-Dor-030900 Dipodomys ordii 44.64 5.00e-40 157.00
IUUC-Ete-033000 Echinops telfairi 32.48 2.00e-11 62.40
IUUC-Eca-034338 Equus caballus 36.80 2.00e-39 155.00
IUUC-Eeu-034585 Erinaceus europaeus 44.32 6.00e-21 94.00
IUUC-Fal-037525 Ficedula albicollis 44.05 4.00e-39 154.00
IUUC-Gmo-039718 Gadus morhua 43.86 6.00e-40 157.00
IUUC-Gga-040774 Gallus gallus 44.64 2.00e-40 159.00
IUUC-Gac-041671 Gasterosteus aculeatus 43.86 6.00e-36 144.00
IUUC-Gma-042801 Glycine max 73.31 2.00e-93 335.00
IUUC-Ggo-044759 Gorilla gorilla 34.90 2.00e-26 112.00
IUUC-Hsa-046591 Homo sapiens 36.86 8.00e-41 160.00
IUUC-Hvu-047492 Hordeum vulgare 67.20 3.00e-83 301.00
IUUC-Itr-048851 Ictidomys tridecemlineatus 31.90 3.00e-17 81.60
IUUC-Lch-049519 Latimeria chalumnae 34.67 4.00e-27 114.00
IUUC-Lpe-050819 Leersia perrieri 66.53 2.00e-83 301.00
IUUC-Loc-051816 Lepisosteus oculatus 37.01 2.00e-41 162.00
IUUC-Laf-053784 Loxodonta africana 44.64 1.00e-40 159.00
IUUC-Mcc-055283 Macaca mulatta 36.86 4.00e-41 161.00
IUUC-Meu-056589 Macropus eugenii 34.25 3.00e-34 138.00
IUUC-Mtr-058233 Medicago truncatula 68.93 1.00e-100 358.00
IUUC-Mla-059013 Melampsora laricipopulina 30.00 2.00e-14 72.40
IUUC-Mga-059301 Meleagris gallopavo 44.64 9.00e-41 160.00
IUUC-Mmr-061038 Microcebus murinus 37.07 1.00e-41 163.00
IUUC-Mdo-062927 Monodelphis domestica 44.44 5.00e-40 157.00
IUUC-Mmu-063600 Mus musculus 44.64 2.00e-40 158.00
IUUC-Mpu-065897 Mustela putorius furo 36.47 3.00e-38 151.00
IUUC-Mlu-067543 Myotis lucifugus 44.79 3.00e-39 154.00
IUUC-Nle-069430 Nomascus leucogenys 42.60 9.00e-37 146.00
IUUC-Opr-070550 Ochotona princeps 31.60 4.00e-27 114.00
IUUC-Ont-071723 Oreochromis niloticus 43.86 3.00e-36 144.00
IUUC-Oan-073569 Ornithorhynchus anatinus 43.86 5.00e-40 157.00
IUUC-Ocu-074632 Oryctolagus cuniculus 37.31 1.00e-37 149.00
IUUC-Oba-075288 Oryza barthii 65.12 1.00e-86 312.00
IUUC-Obr-076050 Oryza brachyantha 75.86 3.00e-79 288.00
IUUC-Ogl-077174 Oryza glaberrima 65.12 1.00e-86 312.00
IUUC-Ogu-078006 Oryza glumaepatula 65.12 1.00e-86 312.00
IUUC-Oin-079278 Oryza indica 62.69 3.00e-84 304.00
IUUC-Olo-080941 Oryza longistaminata 65.12 1.00e-86 312.00
IUUC-Ome-081172 Oryza meridionalis 65.74 2.00e-86 311.00
IUUC-Oni-082239 Oryza nivara 64.73 3.00e-86 310.00
IUUC-Opu-083939 Oryza punctata 65.12 5.00e-86 310.00
IUUC-Oru-084393 Oryza rufipogon 65.12 1.00e-86 312.00
IUUC-Osa-086080 Oryza sativa 64.73 2.00e-86 311.00
IUUC-Ola-087566 Oryzias latipes 37.98 6.00e-37 147.00
IUUC-Oga-088617 Otolemur garnettii 29.81 3.00e-19 88.60
IUUC-Oar-090052 Ovis aries 44.05 1.00e-38 152.00
IUUC-Ptr-091435 Pan troglodytes 36.86 4.00e-41 161.00
IUUC-Pan-092742 Papio anubis 35.66 1.00e-38 152.00
IUUC-Psi-093313 Pelodiscus sinensis 37.40 2.00e-40 158.00
IUUC-Pma-094374 Petromyzon marinus 42.77 4.00e-36 144.00
IUUC-Ppa-095601 Physcomitrella patens 49.77 4.00e-62 231.00
IUUC-Pfo-097327 Poecilia formosa 37.35 2.00e-38 152.00
IUUC-Pab-098435 Pongo abelii 35.83 2.00e-37 149.00
IUUC-Pca-101022 Procavia capensis 44.25 8.00e-22 97.10
IUUC-Ppe-101545 Prunus persica 78.32 1.00e-96 345.00
IUUC-Pva-102844 Pteropus vampyrus 36.72 2.00e-40 159.00
IUUC-Rno-104896 Rattus norvegicus 44.64 1.00e-40 159.00
IUUC-Sha-107106 Sarcophilus harrisii 44.64 3.00e-40 158.00
IUUC-Sit-110477 Setaria italica 64.31 2.00e-84 304.00
IUUC-Sly-111416 Solanum lycopersicum 64.02 6.00e-52 196.00
IUUC-Stu-112227 Solanum tuberosum 64.88 2.00e-56 211.00
IUUC-Sar-113534 Sorex araneus 36.90 4.00e-39 154.00
IUUC-Sbi-114751 Sorghum bicolor 63.64 5.00e-82 296.00
IUUC-Ssc-115274 Sus scrofa 36.86 2.00e-41 162.00
IUUC-Tgu-117426 Taeniopygia guttata 44.79 1.00e-38 152.00
IUUC-Tru-118059 Takifugu rubripes 37.30 1.00e-37 149.00
IUUC-Tsy-119448 Tarsius syrichta 36.31 4.00e-27 114.00
IUUC-Tni-120681 Tetraodon nigroviridis 44.35 3.00e-23 99.80
IUUC-Tca-121442 Theobroma cacao 70.82 7.00e-105 372.00
IUUC-Tae-123969 Triticum aestivum 65.18 6.00e-76 276.00
IUUC-Tme-127036 Tuber melanosporum 34.21 4.70e-01 30.00
IUUC-Tbe-127638 Tupaia belangeri 34.38 2.00e-29 122.00
IUUC-Ttr-129288 Tursiops truncatus 32.14 8.00e-30 123.00
IUUC-Uma-129359 Ustilago maydis 34.68 1.00e-23 104.00
IUUC-Vpa-130788 Vicugna pacos 36.80 2.00e-39 155.00
IUUC-Vvi-131227 Vitis vinifera 71.37 5.00e-85 306.00
IUUC-Xtr-132147 Xenopus tropicalis 44.19 3.00e-40 158.00
IUUC-Xma-133144 Xiphophorus maculatus 36.96 5.00e-38 150.00
Created Date 25-Jun-2017

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