iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067371

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02059240

Gene Name

USP36

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000013070.2	ENSMLUT00000013081.2	ENSMLUP00000011898.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.70e-80	269.7	122	420

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           Gl+NlgNtC++NS++QcL+ +p+l+++ll+ ++ ++++     + + ++l+ +q+ + +   ++ +a++p ++++ l+k+a++f+  +q
   Q: 122  GLHNLGNTCFLNSTVQCLTYTPPLANYLLSrEHARSCP-----QGSFCMLCVMQNHLVQAFANSGNAIKPVSFIRDLRKIARHFRFGNQ 205
           9*****************************33444443.....345677778888887888**************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da+Efl++ +d++++++                  ls  a+ + +++ ++l++++F+g l+s++kc  c++vs +++p ld+ l++++
   Q: 206  EDAHEFLRYTIDAMQKAC------------------LSGYAKLDRQTQATTLVHQIFGGCLRSRVKCSVCKSVSDTYDPYLDVALEIRQ 276
           ******************..................55667788999****************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
                  ++  +Le f+k++ l gen+y c +ckkk+ a+k++++++ ++vL+l LkRf    ++ s  ki+k v +p+ L+++p++++
   Q: 277  AA-----NIVRALELFVKPDALSGENAYMCARCKKKVPASKRFTIHRASNVLTLSLKRF----ANFSGGKITKDVGYPEFLNIRPYMSQ 356
           **.....9***************************************************....668899******************** PP
   S: 268  peekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           ++ +   ++ Y L+av+vHsG s++ GHY++yvk ++g+W++++Ds V++++ + vl+   ++aYvlfY 
   Q: 357  SSGE---PVVYGLYAVLVHSGySCHAGHYYCYVKASNGQWYQMNDSLVHSSNIKVVLN---QQAYVLFYL 420
           5544...9**************************************************...********6 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MPIVDKLKEA LKPGRKDSAD DGELGRLLAA SAKKVLLQKI EFEPASRSFS YQLQSLRSKY 60
VLLNPRPEGT ARPRGDEPPA RRQGCERVYE SGGDGVPAPQ KVLFPVERLS LKWERVYRVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCATCG TCGACAAGCT GAAGGAAGCC CTGAAACCCG GCCGCAAGGA CTCGGCCGAC 60
GATGGCGAGC TGGGGAGGCT GCTGGCCGCC TCTGCCAAGA AGGTCCTGCT GCAGAAGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016607--C:nuclear speck
GO:0005730--C:nucleolus
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0016579--P:protein deubiquitination
GO:1903146--P:regulation of mitophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002092	Ailuropoda melanoleuca	70.93	0.00e+00	1229.00
IUUC-Aca-005360	Anolis carolinensis	62.39	0.00e+00	879.00
IUUC-Bta-013047	Bos taurus	68.91	0.00e+00	1212.00
IUUC-Bdi-014036	Brachypodium distachyon	46.84	7.00e-86	311.00
IUUC-Bol-015086	Brassica oleracea	44.81	9.00e-82	298.00
IUUC-Bra-018046	Brassica rapa	44.81	3.00e-82	300.00
IUUC-Cja-019203	Callithrix jacchus	65.84	0.00e+00	1113.00
IUUC-Cfa-020586	Canis familiaris	71.20	0.00e+00	1276.00
IUUC-Cpo-021804	Cavia porcellus	63.21	0.00e+00	1100.00
IUUC-Cre-022988	Chlamydomonas reinhardtii	47.09	4.00e-51	194.00
IUUC-Csa-023137	Chlorocebus sabaeus	68.02	0.00e+00	1199.00
IUUC-Cin-025230	Ciona intestinalis	52.89	3.00e-97	348.00
IUUC-Cne-027049	Cryptococcus neoformans	34.46	1.00e-39	157.00
IUUC-Cme-027339	Cyanidioschyzon merolae	37.67	3.00e-61	229.00
IUUC-Dre-028587	Danio rerio	73.98	0.00e+00	800.00
IUUC-Dno-029149	Dasypus novemcinctus	65.81	0.00e+00	1156.00
IUUC-Dor-030836	Dipodomys ordii	67.83	0.00e+00	894.00
IUUC-Dme-032119	Drosophila melanogaster	33.83	4.00e-71	263.00
IUUC-Ete-032567	Echinops telfairi	67.12	0.00e+00	822.00
IUUC-Eca-033600	Equus caballus	73.27	0.00e+00	1294.00
IUUC-Eeu-035206	Erinaceus europaeus	52.11	2.00e-117	417.00
IUUC-Fca-036392	Felis catus	63.08	4.00e-142	498.00
IUUC-Fal-036852	Ficedula albicollis	69.47	3.00e-161	562.00
IUUC-Gmo-039033	Gadus morhua	72.96	0.00e+00	785.00
IUUC-Gga-040664	Gallus gallus	76.04	0.00e+00	732.00
IUUC-Gac-042176	Gasterosteus aculeatus	67.61	0.00e+00	795.00
IUUC-Ggo-045437	Gorilla gorilla	68.13	0.00e+00	1166.00
IUUC-Hsa-046863	Homo sapiens	67.93	0.00e+00	1172.00
IUUC-Itr-048655	Ictidomys tridecemlineatus	66.93	0.00e+00	1021.00
IUUC-Lch-050120	Latimeria chalumnae	65.49	0.00e+00	731.00
IUUC-Lpe-051574	Leersia perrieri	38.00	3.00e-81	296.00
IUUC-Loc-052796	Lepisosteus oculatus	60.27	0.00e+00	765.00
IUUC-Laf-054243	Loxodonta africana	65.91	0.00e+00	1153.00
IUUC-Mcc-055762	Macaca mulatta	66.96	0.00e+00	1184.00
IUUC-Meu-056697	Macropus eugenii	61.09	0.00e+00	1102.00
IUUC-Mtr-058537	Medicago truncatula	49.84	5.00e-84	305.00
IUUC-Mla-059049	Melampsora laricipopulina	42.19	1.00e-57	217.00
IUUC-Mga-059359	Meleagris gallopavo	73.13	5.00e-152	531.00
IUUC-Mmr-060966	Microcebus murinus	67.25	0.00e+00	1145.00
IUUC-Mdo-062733	Monodelphis domestica	68.97	0.00e+00	971.00
IUUC-Mmu-064331	Mus musculus	66.07	0.00e+00	1177.00
IUUC-Mac-064815	Musa acuminata	47.19	1.00e-85	310.00
IUUC-Mpu-065759	Mustela putorius furo	68.47	0.00e+00	1169.00
IUUC-Nle-070087	Nomascus leucogenys	66.43	0.00e+00	1141.00
IUUC-Opr-070729	Ochotona princeps	66.08	0.00e+00	902.00
IUUC-Ont-071346	Oreochromis niloticus	75.34	0.00e+00	798.00
IUUC-Oan-072931	Ornithorhynchus anatinus	74.33	0.00e+00	813.00
IUUC-Ocu-074823	Oryctolagus cuniculus	67.53	0.00e+00	853.00
IUUC-Oba-075866	Oryza barthii	46.35	2.00e-84	307.00
IUUC-Obr-076408	Oryza brachyantha	38.16	2.00e-85	310.00
IUUC-Ogl-077239	Oryza glaberrima	46.52	4.00e-85	309.00
IUUC-Ogu-078064	Oryza glumaepatula	46.52	5.00e-85	309.00
IUUC-Oin-079157	Oryza indica	46.52	4.00e-85	309.00
IUUC-Olo-080231	Oryza longistaminata	43.99	4.00e-76	280.00
IUUC-Ome-081746	Oryza meridionalis	47.06	6.00e-84	305.00
IUUC-Oni-082339	Oryza nivara	46.52	4.00e-85	309.00
IUUC-Opu-083194	Oryza punctata	46.52	2.00e-84	308.00
IUUC-Oru-085083	Oryza rufipogon	46.52	3.00e-85	310.00
IUUC-Osa-086180	Oryza sativa	46.52	4.00e-85	309.00
IUUC-Ola-087255	Oryzias latipes	69.38	0.00e+00	810.00
IUUC-Olu-087773	Ostreococcus lucimarinus	45.71	3.00e-72	265.00
IUUC-Oga-088818	Otolemur garnettii	67.79	0.00e+00	1000.00
IUUC-Oar-089410	Ovis aries	67.83	0.00e+00	1203.00
IUUC-Ptr-090680	Pan troglodytes	68.43	0.00e+00	1025.00
IUUC-Pan-092482	Papio anubis	67.34	0.00e+00	1194.00
IUUC-Pma-094591	Petromyzon marinus	55.21	3.00e-51	194.00
IUUC-Ppa-095853	Physcomitrella patens	48.41	2.00e-92	333.00
IUUC-Pfo-096807	Poecilia formosa	71.80	0.00e+00	819.00
IUUC-Pab-098724	Pongo abelii	68.49	0.00e+00	1198.00
IUUC-Pop-099693	Populus trichocarpa	41.43	5.00e-83	302.00
IUUC-Pca-100117	Procavia capensis	74.49	2.00e-144	507.00
IUUC-Pva-102883	Pteropus vampyrus	65.67	0.00e+00	1034.00
IUUC-Pgr-103270	Puccinia graminis	45.94	2.00e-68	253.00
IUUC-Ptt-103887	Puccinia triticina	44.34	6.00e-68	251.00
IUUC-Rno-105340	Rattus norvegicus	61.90	0.00e+00	1049.00
IUUC-Sha-107019	Sarcophilus harrisii	60.43	0.00e+00	1101.00
IUUC-Sja-107805	Schizosaccharomyces japonicus	42.49	1.00e-76	280.00
IUUC-Spo-108119	Schizosaccharomyces pombe	43.71	1.00e-82	300.00
IUUC-Smo-108763	Selaginella moellendorffii	47.40	2.00e-81	295.00
IUUC-Sit-110536	Setaria italica	46.52	2.00e-79	290.00
IUUC-Sly-111722	Solanum lycopersicum	40.00	2.00e-79	291.00
IUUC-Stu-112912	Solanum tuberosum	40.49	9.00e-81	295.00
IUUC-Sbi-114477	Sorghum bicolor	46.84	4.00e-87	316.00
IUUC-Sre-114924	Sporisorium reilianum	40.77	7.00e-66	245.00
IUUC-Ssc-116022	Sus scrofa	84.51	0.00e+00	872.00
IUUC-Tgu-116976	Taeniopygia guttata	72.04	4.00e-162	564.00
IUUC-Tru-118391	Takifugu rubripes	63.60	0.00e+00	816.00
IUUC-Tsy-119253	Tarsius syrichta	53.75	0.00e+00	665.00
IUUC-Tni-120064	Tetraodon nigroviridis	77.02	0.00e+00	786.00
IUUC-Tae-125259	Triticum aestivum	48.58	3.00e-88	320.00
IUUC-Tur-126014	Triticum urartu	47.71	7.00e-84	305.00
IUUC-Tbe-127377	Tupaia belangeri	56.11	0.00e+00	654.00
IUUC-Ttr-129259	Tursiops truncatus	62.97	0.00e+00	1021.00
IUUC-Uma-129416	Ustilago maydis	41.60	4.00e-67	249.00
IUUC-Vpa-130568	Vicugna pacos	66.38	3.00e-43	170.00
IUUC-Xtr-132944	Xenopus tropicalis	75.83	0.00e+00	668.00
IUUC-Xma-133735	Xiphophorus maculatus	63.92	0.00e+00	820.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence