iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011688

Ensembl Protein ID

ENSAMXP00000021775.1

UniProt Accession

W5LPI4; W5LPI4_ASTMX

Genbank Protein ID

ENSAMXP00000021775

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01031500

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000021157.1	ENSAMXT00000021775.1	ENSAMXP00000021775.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-46	159.9	150	479

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaee.fsg 86
           +Gl+N+ +  Y N vLQ+Lsn+p+lr+++le+++ +  ++ p +    l++ + +l+++lw   + k +vsp+e+l+a+  ++++ f+ 
   Q: 150  VGLNNIKANDYANVVLQALSNVPPLRNYFLEEENYHGIRRPPGDIMFLLVQRFGELMRKLWnpRNFKAHVSPHEMLQAVVLCSKKtFQI 238
           6******************************99988889999*******************999999**************99999*** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlk................sqikclec 159
           ++q Da +fl+++l++l+ +l                           +kk++s++++ Fqg+++                + +  +e 
   Q: 239  TKQGDAVDFLSWFLNALHGAL-------------------------GGTKKKSSIVTKAFQGSMRifskklphpdlpaeekEALLQKEE 302
           *********************.........................3455666666666666666666666666666665588999999 PP
   S: 160  dnvssreepfldlslpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsf 239
            +++  e++fl+l+l++p     k e          l ++L +f  + e e    y++ k     +  k+++l+klP++Li+ +kRf  
   Q: 303  YQEKMLESTFLYLTLDLPTAPLYKDEkeqliipqvPLFNILGKFNGNTEKE----YKTYK----ENFLKRFQLTKLPPYLIFCIKRF-- 381
           9999**************777666664555666667777777777766666....44443....44899******************.. PP
   S: 240  seeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleet 326
           ++++ + ek+ + v+fp++ +dl++++t++ ++ +++++Y+L+a vvH G++ +G Y  +v +  +gkW+++ D +V  +  + +    
   Q: 382  TKNNFFVEKNPTIVNFPITnVDLREYLTEEAQATEKSTTYDLVANVVHDGKPTEGAYRIHVLHhGTGKWYELQDLQVIDILPQMITL-- 468
           88889********************************************************9935666******************9.. PP
   S: 327  gstaYvlfYkrr 338
            s+aY+ ++kr+
   Q: 469  -SEAYIQIWKRK 479
           .*******9985 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MAGVKRERDA EDEEEEEVRG KVPDRRSRHC PYLDTINRSV LDFDFEKLCS ISLSHINVYA 60
CLICGKYFQG RGLKSHAYTH SVQFTHHVFL NLHTLKFYCL PDNYEIIDSS LEDITYVLKP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGAATCATA TAAATAGACA CTTTAGGACT TGTGGAAAGA ATTACCTCAA AAGACTAATT 60
TATCATTTTT AGAACAGTAG AACAGCAACA ACATAACAGC AGCACAGTGT GAGCAACAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR033809--USP39
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0048855--P:adenohypophysis morphogenesis
GO:0016579--P:protein deubiquitination
GO:0043484--P:regulation of RNA splicing
GO:0000245--P:spliceosomal complex assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000483	Aegilops tauschii	53.15	1.00e-129	456.00
IUUC-Aml-001846	Ailuropoda melanoleuca	89.46	0.00e+00	873.00
IUUC-Atr-002758	Amborella trichopoda	51.81	2.00e-131	462.00
IUUC-Apl-003336	Anas platyrhynchos	83.03	5.00e-159	553.00
IUUC-Aca-004846	Anolis carolinensis	89.45	0.00e+00	845.00
IUUC-Aly-005683	Arabidopsis lyrata	51.54	8.00e-121	427.00
IUUC-Ath-007661	Arabidopsis thaliana	51.32	2.00e-121	429.00
IUUC-Ago-007802	Ashbya gossypii	31.45	9.00e-59	221.00
IUUC-Acl-008304	Aspergillus clavatus	43.50	1.00e-94	340.00
IUUC-Afl-008735	Aspergillus flavus	59.66	2.00e-40	160.00
IUUC-Afu-009100	Aspergillus fumigatus	41.92	3.00e-93	336.00
IUUC-Ani-009138	Aspergillus nidulans	50.37	3.00e-96	345.00
IUUC-Ang-009661	Aspergillus niger	46.17	3.00e-98	352.00
IUUC-Aor-010235	Aspergillus oryzae	40.39	3.00e-83	302.00
IUUC-Ate-010346	Aspergillus terreus	38.16	3.00e-75	276.00
IUUC-Bgr-011998	Blumeria graminis	47.61	1.00e-114	407.00
IUUC-Bta-013407	Bos taurus	89.25	0.00e+00	869.00
IUUC-Bci-013977	Botrytis cinerea	48.48	2.00e-115	409.00
IUUC-Bdi-014361	Brachypodium distachyon	52.92	5.00e-134	471.00
IUUC-Bol-016317	Brassica oleracea	50.43	1.00e-119	423.00
IUUC-Bra-017952	Brassica rapa	51.54	7.00e-121	427.00
IUUC-Cel-018491	Caenorhabditis elegans	65.27	0.00e+00	635.00
IUUC-Cja-019134	Callithrix jacchus	89.25	0.00e+00	871.00
IUUC-Cfa-020098	Canis familiaris	89.25	0.00e+00	870.00
IUUC-Cpo-021595	Cavia porcellus	89.46	0.00e+00	870.00
IUUC-Cre-022886	Chlamydomonas reinhardtii	50.00	6.00e-31	125.00
IUUC-Csa-024121	Chlorocebus sabaeus	89.25	0.00e+00	870.00
IUUC-Cho-025057	Choloepus hoffmanni	71.43	5.00e-80	291.00
IUUC-Cin-025473	Ciona intestinalis	63.21	5.00e-62	230.00
IUUC-Csv-025815	Ciona savignyi	80.99	2.00e-120	426.00
IUUC-Cgl-026416	Colletotrichum gloeosporioides	44.44	1.00e-110	393.00
IUUC-Cne-026802	Cryptococcus neoformans	43.17	7.00e-102	364.00
IUUC-Dre-027870	Danio rerio	95.35	0.00e+00	901.00
IUUC-Dno-029655	Dasypus novemcinctus	89.42	0.00e+00	867.00
IUUC-Dor-030762	Dipodomys ordii	89.25	0.00e+00	868.00
IUUC-Dse-031441	Dothistroma septosporum	45.82	5.00e-111	394.00
IUUC-Dme-032101	Drosophila melanogaster	65.57	4.00e-180	624.00
IUUC-Ete-032841	Echinops telfairi	85.16	0.00e+00	829.00
IUUC-Eca-033463	Equus caballus	89.25	0.00e+00	868.00
IUUC-Eeu-034438	Erinaceus europaeus	64.15	3.00e-168	585.00
IUUC-Fca-035774	Felis catus	89.25	0.00e+00	870.00
IUUC-Fal-036988	Ficedula albicollis	89.37	0.00e+00	870.00
IUUC-Fox-037895	Fusarium oxysporum	46.15	6.00e-109	387.00
IUUC-Fso-038450	Fusarium solani	46.84	8.00e-111	394.00
IUUC-Gmo-038874	Gadus morhua	92.59	0.00e+00	863.00
IUUC-Ggr-040115	Gaeumannomyces graminis	44.51	3.00e-105	375.00
IUUC-Gac-041650	Gasterosteus aculeatus	92.02	0.00e+00	900.00
IUUC-Gma-043697	Glycine max	49.57	5.00e-131	461.00
IUUC-Ggo-044707	Gorilla gorilla	83.44	0.00e+00	794.00
IUUC-Hsa-046041	Homo sapiens	89.25	0.00e+00	870.00
IUUC-Hvu-047816	Hordeum vulgare	51.51	3.00e-123	435.00
IUUC-Itr-048945	Ictidomys tridecemlineatus	89.70	5.00e-177	613.00
IUUC-Lch-050419	Latimeria chalumnae	89.72	0.00e+00	879.00
IUUC-Lpe-051593	Leersia perrieri	53.48	1.00e-134	473.00
IUUC-Loc-052930	Lepisosteus oculatus	94.43	0.00e+00	897.00
IUUC-Lma-053256	Leptosphaeria maculans	47.62	2.00e-114	406.00
IUUC-Laf-053555	Loxodonta africana	89.03	0.00e+00	865.00
IUUC-Mcc-055630	Macaca mulatta	89.25	0.00e+00	870.00
IUUC-Meu-056579	Macropus eugenii	85.40	2.00e-161	562.00
IUUC-Mor-057078	Magnaporthe oryzae	46.25	3.00e-108	385.00
IUUC-Mpo-057607	Magnaporthe poae	38.55	3.00e-85	309.00
IUUC-Mtr-058644	Medicago truncatula	50.66	5.00e-130	457.00
IUUC-Mla-059120	Melampsora laricipopulina	42.36	7.00e-101	361.00
IUUC-Mvi-060429	Microbotryum violaceum	47.67	5.00e-71	261.00
IUUC-Mmr-061313	Microcebus murinus	88.51	0.00e+00	871.00
IUUC-Mdo-062801	Monodelphis domestica	89.68	0.00e+00	874.00
IUUC-Mmu-064424	Mus musculus	89.85	0.00e+00	884.00
IUUC-Mac-064694	Musa acuminata	51.81	9.00e-129	453.00
IUUC-Mpu-065980	Mustela putorius furo	89.45	0.00e+00	769.00
IUUC-Mlu-067007	Myotis lucifugus	89.10	0.00e+00	869.00
IUUC-Nfi-068274	Neosartorya fischeri	42.44	3.00e-93	335.00
IUUC-Ncr-068829	Neurospora crassa	47.20	3.00e-107	382.00
IUUC-Nle-069171	Nomascus leucogenys	89.63	0.00e+00	867.00
IUUC-Opr-070494	Ochotona princeps	82.29	0.00e+00	774.00
IUUC-Ont-072290	Oreochromis niloticus	93.60	0.00e+00	924.00
IUUC-Oan-073099	Ornithorhynchus anatinus	89.85	0.00e+00	865.00
IUUC-Ocu-074642	Oryctolagus cuniculus	89.25	0.00e+00	869.00
IUUC-Oba-075886	Oryza barthii	51.46	2.00e-134	473.00
IUUC-Obr-076220	Oryza brachyantha	51.26	1.00e-134	473.00
IUUC-Ogl-077682	Oryza glaberrima	52.44	1.00e-134	473.00
IUUC-Ogu-078492	Oryza glumaepatula	52.23	3.00e-134	471.00
IUUC-Oin-079956	Oryza indica	52.44	1.00e-134	473.00
IUUC-Olo-080239	Oryza longistaminata	47.03	9.00e-107	382.00
IUUC-Ome-081573	Oryza meridionalis	51.25	5.00e-135	474.00
IUUC-Oni-082975	Oryza nivara	52.44	1.00e-134	473.00
IUUC-Opu-083724	Oryza punctata	52.43	6.00e-135	474.00
IUUC-Oru-084566	Oryza rufipogon	52.44	1.00e-134	473.00
IUUC-Osa-086008	Oryza sativa	52.44	2.00e-134	473.00
IUUC-Ola-086967	Oryzias latipes	93.36	0.00e+00	891.00
IUUC-Olu-087614	Ostreococcus lucimarinus	43.57	2.00e-98	352.00
IUUC-Oga-088047	Otolemur garnettii	77.78	6.00e-164	570.00
IUUC-Oar-089393	Ovis aries	89.25	0.00e+00	870.00
IUUC-Ptr-090561	Pan troglodytes	89.25	0.00e+00	870.00
IUUC-Pan-091812	Papio anubis	89.25	0.00e+00	870.00
IUUC-Psi-093507	Pelodiscus sinensis	88.44	2.00e-152	531.00
IUUC-Pno-095104	Phaeosphaeria nodorum	47.11	5.00e-113	401.00
IUUC-Ppa-095995	Physcomitrella patens	52.58	6.00e-137	481.00
IUUC-Pfo-096754	Poecilia formosa	92.72	0.00e+00	917.00
IUUC-Pab-098053	Pongo abelii	89.25	0.00e+00	870.00
IUUC-Pop-099230	Populus trichocarpa	51.50	5.00e-135	474.00
IUUC-Pca-100407	Procavia capensis	81.51	0.00e+00	773.00
IUUC-Ppe-101699	Prunus persica	51.52	2.00e-130	459.00
IUUC-Pva-103159	Pteropus vampyrus	87.47	0.00e+00	824.00
IUUC-Pgr-103433	Puccinia graminis	42.83	5.00e-107	382.00
IUUC-Ptt-103701	Puccinia triticina	40.08	4.00e-95	342.00
IUUC-Pte-104281	Pyrenophora teres	47.39	6.00e-113	400.00
IUUC-Pyt-104714	Pyrenophora triticirepentis	47.39	9.00e-113	400.00
IUUC-Rno-105531	Rattus norvegicus	89.68	0.00e+00	887.00
IUUC-Sce-106368	Saccharomyces cerevisiae	29.54	2.00e-45	176.00
IUUC-Sha-107093	Sarcophilus harrisii	89.89	0.00e+00	871.00
IUUC-Sja-108004	Schizosaccharomyces japonicus	44.78	6.00e-116	410.00
IUUC-Spo-108018	Schizosaccharomyces pombe	47.48	3.00e-114	405.00
IUUC-Ssl-108460	Sclerotinia sclerotiorum	46.14	1.00e-106	380.00
IUUC-Smo-108892	Selaginella moellendorffii	53.29	8.00e-135	473.00
IUUC-Sit-110782	Setaria italica	51.37	2.00e-135	475.00
IUUC-Sly-111308	Solanum lycopersicum	53.81	2.00e-140	492.00
IUUC-Stu-112447	Solanum tuberosum	54.03	4.00e-141	494.00
IUUC-Sar-113352	Sorex araneus	82.21	0.00e+00	700.00
IUUC-Sbi-114806	Sorghum bicolor	52.33	5.00e-135	474.00
IUUC-Sre-115059	Sporisorium reilianum	49.82	1.00e-73	270.00
IUUC-Ssc-115677	Sus scrofa	89.09	3.00e-176	610.00
IUUC-Tru-118478	Takifugu rubripes	91.74	0.00e+00	912.00
IUUC-Tsy-119082	Tarsius syrichta	77.03	0.00e+00	656.00
IUUC-Tni-120419	Tetraodon nigroviridis	91.53	0.00e+00	890.00
IUUC-Tca-121294	Theobroma cacao	52.03	3.00e-140	491.00
IUUC-Tre-121962	Trichoderma reesei	46.78	7.00e-105	374.00
IUUC-Tvi-122280	Trichoderma virens	46.22	3.00e-112	399.00
IUUC-Tae-124442	Triticum aestivum	54.21	6.00e-136	477.00
IUUC-Tur-126551	Triticum urartu	54.21	1.00e-135	476.00
IUUC-Tme-126959	Tuber melanosporum	48.38	2.00e-117	416.00
IUUC-Tbe-127737	Tupaia belangeri	88.89	0.00e+00	835.00
IUUC-Ttr-129211	Tursiops truncatus	93.31	5.00e-137	481.00
IUUC-Uma-129591	Ustilago maydis	40.30	9.00e-98	351.00
IUUC-Vda-129674	Verticillium dahliae	44.00	4.00e-97	348.00
IUUC-Vpa-130793	Vicugna pacos	82.89	0.00e+00	768.00
IUUC-Xtr-132430	Xenopus tropicalis	86.85	0.00e+00	856.00
IUUC-Xma-133515	Xiphophorus maculatus	92.86	0.00e+00	910.00
IUUC-Yli-134488	Yarrowia lipolytica	38.38	3.00e-76	278.00
IUUC-Zma-134748	Zea mays	52.11	5.00e-135	474.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence