iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Spo-108149

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Probable ubiquitin carboxyl-terminal hydrolase 7; Deubiquitinating enzyme 7; Ubiquitin thioesterase 7; Ubiquitin-specific-processing protease 7

Genbank Nucleotide ID

CU329670

Gene Name

ubp7; SPAC23G3.08c

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPAC23G3.08c	SPAC23G3.08c.1	SPAC23G3.08c.1:pep

Annotation

mRNA Expression
GEO
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.00e-68	228.5	209	874

Active Site

Position(s)	Description	Evidence
217	Nucleophile	ECO:0000255\|PROSITE-ProRule:PRU10092, ECO:0000255\|PROSITE-ProRule:PRU10093}
812	Proton acceptor	ECO:0000255\|PROSITE-ProRule:PRU10092, ECO:0000255\|PROSITE-ProRule:PRU10093}

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle...kkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           GlkNlg+tC++NS+LQ+L +++ l + +     ++++ + ++  k+p+ +ll+++ k++e ++  +++ +++ p++++  +++++++fs++
   Q: 209  GLKNLGATCFFNSTLQVLCACEALHDVISPfqySHSSVIVRKLTKSPESSLLSAFIKFLETFYksDGTISVYRPTTFFGEFRRLHPQFSES 299
           9*************************9998888788888888889*****************966666779******************** PP
   S: 88   eqqDaqEflaflldqleeelkk..........................eknkpkeeeeeedkselsde....................... 129
            qqDa+E+l+ lld+l +e  +                          +                  +                       
   Q: 300  VQQDAHELLRLLLDDLISEEFRvlrfnlnsvsrslqlspcltddeqlsK------------------Sltsfkqvnvtdaslspnshntsd 372
           **************99777756677766665555555555554443330..................244555555555566677777777 PP
   S: 130  ........................................................................................... 129
                                                                                                      
   Q: 373  neqnnedyvsvsslvgsetedityskelsqssdssqhqhdsflpanssplaasstkslpsselldsssdkgqqvfkgqhevagtnsfedpn 463
           788888899999******************************************************************************* PP
   S: 130  ...............................................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
                                                          +   ++ +++ +i+ +F g+l+s ++c++c++++++ ep +dls
   Q: 464  shfnvsnssnheeaspkkevlkspqfqrrsldilrlgelssddmmldKATMDEFSSSLVIKSIFTGRLTSVVMCQSCNEITNTPEPIQDLS 554
           ********************************************998888888888899******************************** PP
   S: 174  lpvpgkeetkke............................................................................... 185
           +p++  +++  +                                                                               
   Q: 555  IPIHYPSSRVSRrhrfhralrsrfsrspkkssvkivvdnanddtdqapttnssslnenllgghasendkslkqspfqkltrrlsdlsvnss 645
           ****888765558999*************************************************************************** PP
   S: 186  .............................slqdcLesftkeeelegenkyycekckkkqe..........................aekkl 221
                                        +l dcL++ft  eel gen++ ce+c+++ +                          a k++
   Q: 646  gqiskqdfdnsnsifsesslsspiieepkTLIDCLKNFTHVEELSGENMFACENCCNQPNevgspakggltsdndkysfnnsvyrnAYKRM 736
           ********************************************************66666777777777777777777777777788888 PP
   S: 222  klkk.lPevLilhLkRf..sfseeq.ksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn....... 301
            l+  lP+v+i+hLkRf  + s+++  +++ki++ +ef +eLdl++f+    +++ ++ +Y+L++v+vHsG+l+ GHYvayv +       
   Q: 737  LLDDpLPPVFIIHLKRFfqEISHDGyANPKKISDFIEFEQELDLNEFVMPHLRAS-SSFRYRLFGVIVHSGTLNYGHYVAYVLShkfldls 826
           886549***********8844444315679*****************99966555.6***************************9999999 PP
   S: 302  ...............ekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                           +++Wl+++D+ V+e++++ev +    +aY+lfY+r
   Q: 827  apstnskdfrseagiPERRWLYISDNIVRESSWDEVSK---VEAYMLFYER 874
           9999988888777777888*******************...9*******98 PP

Organism

Schizosaccharomyces pombe

Protein Sequence
(Fasta)

MPHSNTLIVP STNPFDDPSS IKNGLNNLTS SELVNQMKKE SLAASVKTPS TPPKECSHLK 60
KGVKLSHLKG NARALRDPSK HLCFICTTEK IKREDYELTL CANCGYLFCC NHESDHSRKH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGAGCTTGT AGCAGATAAA CTTATACCCA ACCTCTATTG TAATTCCAAG ATTTCCATAA 60
GCATAAATAG TACACTGATT CAATTGTGCG TGTAAACACT TGTTAAAAGA AATCAGTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

spo:SPAC23G3.08c

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000997	Aegilops tauschii	36.42	1.00e-20	94.00
IUUC-Aml-002331	Ailuropoda melanoleuca	31.51	2.00e-22	99.00
IUUC-Atr-003015	Amborella trichopoda	37.24	2.00e-18	86.30
IUUC-Apl-003512	Anas platyrhynchos	31.86	8.00e-24	103.00
IUUC-Aca-004284	Anolis carolinensis	30.88	1.00e-23	103.00
IUUC-Aly-005494	Arabidopsis lyrata	34.90	4.00e-20	91.70
IUUC-Ath-007211	Arabidopsis thaliana	32.93	1.00e-19	90.10
IUUC-Ame-010735	Astyanax mexicanus	34.50	3.00e-25	107.00
IUUC-Bta-012880	Bos taurus	29.41	2.00e-16	79.00
IUUC-Bdi-014465	Brachypodium distachyon	38.18	7.00e-24	104.00
IUUC-Bol-015191	Brassica oleracea	29.11	4.00e-21	95.10
IUUC-Cja-019144	Callithrix jacchus	30.66	3.00e-21	95.10
IUUC-Cfa-020971	Canis familiaris	31.37	4.00e-22	97.80
IUUC-Cpo-022497	Cavia porcellus	30.99	6.00e-21	94.00
IUUC-Csa-024103	Chlorocebus sabaeus	33.80	9.00e-21	93.60
IUUC-Cho-024315	Choloepus hoffmanni	29.21	1.00e-12	66.60
IUUC-Cin-025775	Ciona intestinalis	31.51	8.00e-13	63.90
IUUC-Csv-026075	Ciona savignyi	31.94	4.00e-21	94.40
IUUC-Cme-027348	Cyanidioschyzon merolae	35.33	5.00e-15	74.30
IUUC-Dre-028106	Danio rerio	32.04	1.00e-24	106.00
IUUC-Dno-029409	Dasypus novemcinctus	33.50	3.00e-20	92.00
IUUC-Ete-032807	Echinops telfairi	35.90	1.00e-18	86.30
IUUC-Eca-034211	Equus caballus	29.90	2.00e-20	92.80
IUUC-Fca-035947	Felis catus	30.88	7.00e-22	97.40
IUUC-Fal-037029	Ficedula albicollis	32.52	4.00e-21	94.70
IUUC-Gmo-039228	Gadus morhua	33.33	2.00e-22	99.00
IUUC-Gga-040823	Gallus gallus	30.88	2.00e-23	101.00
IUUC-Gac-042343	Gasterosteus aculeatus	33.33	2.00e-23	102.00
IUUC-Gma-043919	Glycine max	35.50	3.00e-22	98.60
IUUC-Ggo-045402	Gorilla gorilla	30.99	1.00e-21	96.70
IUUC-Hsa-046430	Homo sapiens	30.19	8.00e-21	93.60
IUUC-Hvu-047146	Hordeum vulgare	36.97	1.00e-23	103.00
IUUC-Itr-048855	Ictidomys tridecemlineatus	27.94	3.00e-15	74.70
IUUC-Lch-049547	Latimeria chalumnae	31.86	5.00e-24	104.00
IUUC-Lpe-050703	Leersia perrieri	38.18	4.00e-26	111.00
IUUC-Loc-051814	Lepisosteus oculatus	34.13	3.00e-23	101.00
IUUC-Laf-053732	Loxodonta africana	34.76	3.00e-20	92.00
IUUC-Mcc-054661	Macaca mulatta	33.80	9.00e-21	93.60
IUUC-Meu-056256	Macropus eugenii	31.86	6.00e-23	100.00
IUUC-Mtr-057945	Medicago truncatula	38.10	3.00e-22	98.60
IUUC-Mla-059026	Melampsora laricipopulina	36.82	1.00e-20	92.80
IUUC-Mga-059833	Meleagris gallopavo	30.88	2.00e-23	102.00
IUUC-Mvi-060391	Microbotryum violaceum	35.48	2.00e-20	92.40
IUUC-Mmr-060952	Microcebus murinus	32.52	1.00e-22	99.80
IUUC-Mdo-062642	Monodelphis domestica	31.37	2.00e-23	102.00
IUUC-Mmu-063945	Mus musculus	29.41	4.00e-21	94.70
IUUC-Mac-064941	Musa acuminata	32.63	9.00e-20	90.10
IUUC-Mpu-065944	Mustela putorius furo	30.66	1.00e-21	96.30
IUUC-Mlu-067511	Myotis lucifugus	35.12	5.00e-23	100.00
IUUC-Nle-069828	Nomascus leucogenys	30.66	4.00e-21	94.70
IUUC-Ont-072121	Oreochromis niloticus	32.23	4.00e-22	98.20
IUUC-Oan-073656	Ornithorhynchus anatinus	32.84	2.00e-23	102.00
IUUC-Ocu-074323	Oryctolagus cuniculus	30.29	2.00e-22	99.00
IUUC-Oba-075094	Oryza barthii	38.18	7.00e-26	110.00
IUUC-Obr-076743	Oryza brachyantha	38.18	9.00e-26	110.00
IUUC-Ogl-077516	Oryza glaberrima	34.81	5.00e-17	80.10
IUUC-Ogu-078851	Oryza glumaepatula	38.18	7.00e-26	110.00
IUUC-Oin-079402	Oryza indica	38.18	7.00e-26	110.00
IUUC-Olo-080431	Oryza longistaminata	37.58	1.00e-25	109.00
IUUC-Ome-081580	Oryza meridionalis	38.18	3.00e-26	112.00
IUUC-Oni-082644	Oryza nivara	38.18	7.00e-26	110.00
IUUC-Opu-083452	Oryza punctata	38.18	7.00e-26	110.00
IUUC-Oru-084546	Oryza rufipogon	38.18	7.00e-26	110.00
IUUC-Osa-085858	Oryza sativa	38.18	8.00e-26	110.00
IUUC-Ola-087238	Oryzias latipes	31.73	1.00e-21	96.70
IUUC-Oga-088713	Otolemur garnettii	34.29	1.00e-20	93.20
IUUC-Oar-089718	Ovis aries	29.41	4.00e-16	78.20
IUUC-Ptr-091358	Pan troglodytes	30.66	3.00e-21	95.10
IUUC-Pan-092293	Papio anubis	33.80	9.00e-21	93.60
IUUC-Psi-093256	Pelodiscus sinensis	29.41	9.00e-22	97.10
IUUC-Ppa-095584	Physcomitrella patens	41.22	5.00e-23	101.00
IUUC-Pfo-097202	Poecilia formosa	33.83	6.00e-23	100.00
IUUC-Pab-098539	Pongo abelii	30.66	5.00e-21	94.70
IUUC-Pop-099136	Populus trichocarpa	37.89	4.00e-24	105.00
IUUC-Pca-101069	Procavia capensis	32.86	3.00e-19	88.60
IUUC-Ppe-101794	Prunus persica	37.41	7.00e-22	97.40
IUUC-Pva-103092	Pteropus vampyrus	34.45	3.00e-21	95.10
IUUC-Rno-105538	Rattus norvegicus	30.62	2.00e-20	92.80
IUUC-Sha-107022	Sarcophilus harrisii	31.53	2.00e-22	99.40
IUUC-Sja-107712	Schizosaccharomyces japonicus	37.70	3.00e-63	234.00
IUUC-Sit-110283	Setaria italica	38.22	6.00e-24	104.00
IUUC-Sly-111491	Solanum lycopersicum	39.86	2.00e-26	112.00
IUUC-Stu-112820	Solanum tuberosum	38.12	1.00e-25	110.00
IUUC-Sbi-113785	Sorghum bicolor	38.32	6.00e-24	104.00
IUUC-Ssc-115870	Sus scrofa	30.39	3.00e-21	95.10
IUUC-Tgu-116907	Taeniopygia guttata	30.39	1.00e-22	100.00
IUUC-Tru-118640	Takifugu rubripes	34.98	1.00e-24	106.00
IUUC-Tsy-118869	Tarsius syrichta	31.86	9.00e-23	100.00
IUUC-Tni-119716	Tetraodon nigroviridis	30.81	1.00e-23	102.00
IUUC-Tca-121701	Theobroma cacao	35.19	5.00e-23	101.00
IUUC-Tae-125305	Triticum aestivum	36.42	8.00e-21	94.00
IUUC-Tur-126773	Triticum urartu	36.30	3.00e-16	78.60
IUUC-Tbe-128041	Tupaia belangeri	27.86	5.00e-18	84.30
IUUC-Ttr-128901	Tursiops truncatus	30.77	3.00e-22	98.60
IUUC-Vpa-130331	Vicugna pacos	34.51	4.00e-16	77.80
IUUC-Xtr-131869	Xenopus tropicalis	34.58	1.00e-23	103.00
IUUC-Xma-133100	Xiphophorus maculatus	32.37	2.00e-23	102.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence