iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afl-008712

Ensembl Protein ID

EED55409

UniProt Accession

B8N368; B8N368_ASPFN

Genbank Protein ID

EED55409.1

Protein Name

Ubiquitin-protein ligase (Tom1), putative

Genbank Nucleotide ID

EQ963473

Gene Name

AFLA_026810

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AFLA_026810	EED55409	EED55409

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	9.30e-120	399.5	762	1094

Active Site

Position(s)	Description	Evidence
1063	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkk.rlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfykll 100
           ++lk+ +l+v+f gEeg+d+gGvtre+++ l++ ++np++ lf   + d++t++pn+ sg+ n ehl +F+f+Gr++gkal++gr+ld+++s+++yk++
   Q: 762  DELKYgKLNVRFHGEEGVDAGGVTREWFQVLARGMFNPNYALFIPVAADRTTFHPNRLSGV-NSEHLMFFKFIGRIIGKALYEGRVLDCHFSRAVYKCI 859
           567755999***************************************************9.56*********************************** PP
   S: 101  lgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfne 199
           lg+++s++d+e++d ++yksl +++en   di+++ ++ tf v+++ +ge ++ +L+++G+nipVt+eNkeeYv++vv+yrl +++keq+++f +Gf+e
   Q: 860  LGRSVSIKDMETLDLDYYKSLLWMLEN---DITDI-ITETFAVETDDFGEKQVIDLVENGSNIPVTQENKEEYVQRVVDYRLVRSVKEQLDNFLKGFHE 954
           *************************99...99999.999************************************************************ PP
   S: 200  viplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfvirk.da 293
           +ip +l+s+F+e+elelli+G +eidv+d+k++t+y++ y+++sp+iqwFw+++++f++eer+++LqFvTg+s++Pl+Gf+el+     ++f i++ ++
   Q: 955  IIPADLISIFNEQELELLISGLPEIDVDDWKANTEYHN-YSASSPQIQWFWRAVRSFDKEERAKLLQFVTGTSKVPLNGFKELEgmngVSRFNIHRdYG 1052
           ************************************66.*********************************************999966677777689 PP
   S: 294  sddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFe 334
           ++drlPs++TCfn+L+LPeY+s+e+l+++L +A++ + + F+
   Q: 1053 NKDRLPSAHTCFNQLDLPEYDSYETLRQRLYTAMTAGsEYFG 1094
           99********************************99877776 PP

Organism

Aspergillus flavus

Protein Sequence
(Fasta)

MEIDPEYLEA LPEELREEVI MQQLAEQRSQ AAAAGEEPSE INPEFLEALP PEIREELLQQ 60
EAADRRRRER ESARRQGASG GAPPRAEDMD AASFLATLDP SLRQAVLADQ PEEILATLGP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAATCG ACCCTGAGTA TCTTGAGGCC CTGCCCGAGG AGCTTAGAGA AGAAGTAATC 60
ATGCAACAAC TTGCAGAGCA ACGCTCTCAG GCAGCTGCAG CTGGTGAAGA GCCTAGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR025527--DUF4414
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF14377--DUF4414
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

afv:AFLA_026810

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	36.23	2.00e-114	407.00
IUUC-Aml-001684	Ailuropoda melanoleuca	46.65	5.00e-134	472.00
IUUC-Atr-003044	Amborella trichopoda	44.71	8.00e-141	494.00
IUUC-Apl-003729	Anas platyrhynchos	52.39	7.00e-102	361.00
IUUC-Aca-005263	Anolis carolinensis	46.64	6.00e-136	478.00
IUUC-Aly-006157	Arabidopsis lyrata	41.37	6.00e-141	495.00
IUUC-Ath-007472	Arabidopsis thaliana	44.31	2.00e-136	479.00
IUUC-Ago-008005	Ashbya gossypii	57.52	0.00e+00	757.00
IUUC-Acl-008254	Aspergillus clavatus	83.58	0.00e+00	1769.00
IUUC-Afu-009022	Aspergillus fumigatus	86.22	0.00e+00	1833.00
IUUC-Ani-009412	Aspergillus nidulans	82.41	0.00e+00	1786.00
IUUC-Ang-009771	Aspergillus niger	88.32	0.00e+00	1869.00
IUUC-Aor-010186	Aspergillus oryzae	97.45	0.00e+00	2050.00
IUUC-Ate-010253	Aspergillus terreus	90.35	0.00e+00	1869.00
IUUC-Ame-011067	Astyanax mexicanus	46.49	5.00e-133	469.00
IUUC-Bgr-012043	Blumeria graminis	61.38	0.00e+00	1271.00
IUUC-Bta-012813	Bos taurus	46.65	4.00e-134	473.00
IUUC-Bci-013995	Botrytis cinerea	61.03	0.00e+00	1232.00
IUUC-Bdi-014884	Brachypodium distachyon	42.52	8.00e-137	481.00
IUUC-Bol-016533	Brassica oleracea	55.64	1.00e-92	330.00
IUUC-Bra-016726	Brassica rapa	41.10	4.00e-139	489.00
IUUC-Cel-018179	Caenorhabditis elegans	51.53	1.00e-129	457.00
IUUC-Cja-018741	Callithrix jacchus	46.65	2.00e-133	470.00
IUUC-Cfa-020083	Canis familiaris	46.65	6.00e-134	472.00
IUUC-Cpo-021923	Cavia porcellus	39.10	3.00e-95	343.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	52.48	1.00e-133	467.00
IUUC-Csa-023853	Chlorocebus sabaeus	46.65	4.00e-134	472.00
IUUC-Cho-024718	Choloepus hoffmanni	56.55	4.00e-123	436.00
IUUC-Cin-025627	Ciona intestinalis	52.25	4.00e-131	462.00
IUUC-Csv-025872	Ciona savignyi	52.01	4.00e-128	449.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	57.89	0.00e+00	1208.00
IUUC-Cne-027095	Cryptococcus neoformans	38.33	0.00e+00	658.00
IUUC-Cme-027267	Cyanidioschyzon merolae	52.27	8.00e-121	427.00
IUUC-Dre-028525	Danio rerio	45.40	2.00e-121	430.00
IUUC-Dno-029680	Dasypus novemcinctus	46.65	3.00e-134	473.00
IUUC-Dor-030902	Dipodomys ordii	48.23	3.00e-113	403.00
IUUC-Dse-031197	Dothistroma septosporum	58.34	0.00e+00	1215.00
IUUC-Dme-032122	Drosophila melanogaster	52.47	3.00e-129	456.00
IUUC-Ete-032966	Echinops telfairi	42.11	5.00e-97	347.00
IUUC-Eca-033915	Equus caballus	45.79	9.00e-132	464.00
IUUC-Eeu-034963	Erinaceus europaeus	53.07	1.00e-131	464.00
IUUC-Fca-035824	Felis catus	46.65	4.00e-134	472.00
IUUC-Fox-037756	Fusarium oxysporum	57.65	0.00e+00	1241.00
IUUC-Fso-038464	Fusarium solani	70.23	0.00e+00	953.00
IUUC-Gmo-039073	Gadus morhua	46.46	2.00e-134	473.00
IUUC-Ggr-039946	Gaeumannomyces graminis	57.88	0.00e+00	1179.00
IUUC-Gga-040309	Gallus gallus	58.31	8.00e-107	377.00
IUUC-Gac-042430	Gasterosteus aculeatus	46.46	3.00e-134	473.00
IUUC-Gma-044216	Glycine max	33.70	4.00e-158	552.00
IUUC-Hsa-046879	Homo sapiens	46.65	5.00e-134	472.00
IUUC-Hvu-047697	Hordeum vulgare	39.35	1.00e-137	484.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	46.65	1.00e-134	473.00
IUUC-Kpa-049228	Komagataella pastoris	59.91	0.00e+00	786.00
IUUC-Lch-050252	Latimeria chalumnae	46.56	2.00e-133	470.00
IUUC-Lpe-051550	Leersia perrieri	43.29	2.00e-137	483.00
IUUC-Loc-052472	Lepisosteus oculatus	47.04	2.00e-135	477.00
IUUC-Lma-053159	Leptosphaeria maculans	62.33	0.00e+00	1337.00
IUUC-Laf-054154	Loxodonta africana	46.65	4.00e-134	473.00
IUUC-Mcc-055085	Macaca mulatta	46.65	4.00e-134	472.00
IUUC-Mor-057201	Magnaporthe oryzae	58.12	0.00e+00	1175.00
IUUC-Mpo-057597	Magnaporthe poae	70.16	0.00e+00	956.00
IUUC-Mtr-057633	Medicago truncatula	33.19	7.00e-157	548.00
IUUC-Mla-058888	Melampsora laricipopulina	58.23	1.00e-144	504.00
IUUC-Mga-059935	Meleagris gallopavo	42.11	2.00e-96	345.00
IUUC-Mvi-060320	Microbotryum violaceum	51.62	0.00e+00	672.00
IUUC-Mmr-060820	Microcebus murinus	46.65	4.00e-134	472.00
IUUC-Mdo-062930	Monodelphis domestica	46.46	2.00e-135	477.00
IUUC-Mmu-063601	Mus musculus	46.65	5.00e-134	472.00
IUUC-Mac-065557	Musa acuminata	40.65	6.00e-131	461.00
IUUC-Mpu-066653	Mustela putorius furo	46.65	6.00e-134	472.00
IUUC-Mlu-067418	Myotis lucifugus	45.57	4.00e-135	476.00
IUUC-Nfi-068278	Neosartorya fischeri	85.77	0.00e+00	1845.00
IUUC-Ncr-068813	Neurospora crassa	68.73	0.00e+00	971.00
IUUC-Nle-069418	Nomascus leucogenys	46.65	5.00e-134	472.00
IUUC-Ont-071300	Oreochromis niloticus	45.42	6.00e-135	475.00
IUUC-Oan-073046	Ornithorhynchus anatinus	46.47	6.00e-135	475.00
IUUC-Ocu-074178	Oryctolagus cuniculus	46.65	3.00e-134	473.00
IUUC-Oba-075757	Oryza barthii	42.33	2.00e-140	493.00
IUUC-Obr-076553	Oryza brachyantha	43.17	3.00e-140	493.00
IUUC-Ogl-077520	Oryza glaberrima	42.33	2.00e-140	493.00
IUUC-Ogu-078278	Oryza glumaepatula	42.33	2.00e-140	493.00
IUUC-Oin-079767	Oryza indica	42.33	2.00e-140	493.00
IUUC-Olo-080380	Oryza longistaminata	42.06	1.00e-138	487.00
IUUC-Ome-081925	Oryza meridionalis	42.06	2.00e-138	486.00
IUUC-Oni-082619	Oryza nivara	42.33	2.00e-140	493.00
IUUC-Opu-083684	Oryza punctata	42.06	9.00e-139	488.00
IUUC-Oru-084501	Oryza rufipogon	42.33	2.00e-140	493.00
IUUC-Osa-086251	Oryza sativa	42.20	5.00e-140	489.00
IUUC-Olu-087813	Ostreococcus lucimarinus	48.89	9.00e-117	411.00
IUUC-Oga-088903	Otolemur garnettii	46.65	4.00e-134	473.00
IUUC-Oar-090210	Ovis aries	46.65	4.00e-134	472.00
IUUC-Pan-092368	Papio anubis	45.81	1.00e-121	431.00
IUUC-Pno-094871	Phaeosphaeria nodorum	61.20	0.00e+00	1280.00
IUUC-Ppa-095657	Physcomitrella patens	39.03	1.00e-132	468.00
IUUC-Pfo-096232	Poecilia formosa	46.46	1.00e-134	474.00
IUUC-Pab-098583	Pongo abelii	46.65	4.00e-134	472.00
IUUC-Pop-099468	Populus trichocarpa	33.25	1.00e-155	543.00
IUUC-Ppe-101641	Prunus persica	45.79	2.00e-137	483.00
IUUC-Pva-102116	Pteropus vampyrus	43.98	5.00e-120	426.00
IUUC-Pgr-103465	Puccinia graminis	49.39	0.00e+00	642.00
IUUC-Ptt-103813	Puccinia triticina	47.54	2.00e-172	599.00
IUUC-Pte-104018	Pyrenophora teres	61.84	0.00e+00	1310.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	62.14	0.00e+00	1312.00
IUUC-Rno-105153	Rattus norvegicus	42.11	7.00e-97	346.00
IUUC-Sce-106449	Saccharomyces cerevisiae	54.46	0.00e+00	722.00
IUUC-Sha-106961	Sarcophilus harrisii	46.46	2.00e-135	477.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	46.62	0.00e+00	886.00
IUUC-Spo-108024	Schizosaccharomyces pombe	45.19	0.00e+00	863.00
IUUC-Smo-109428	Selaginella moellendorffii	40.62	6.00e-135	475.00
IUUC-Sit-110149	Setaria italica	40.25	5.00e-138	485.00
IUUC-Sly-111706	Solanum lycopersicum	42.86	4.00e-138	485.00
IUUC-Stu-112582	Solanum tuberosum	34.75	2.00e-56	212.00
IUUC-Sar-113291	Sorex araneus	53.61	1.00e-129	457.00
IUUC-Sbi-114042	Sorghum bicolor	34.05	4.00e-150	525.00
IUUC-Sre-114958	Sporisorium reilianum	59.72	8.00e-178	614.00
IUUC-Ssc-115754	Sus scrofa	46.65	5.00e-134	472.00
IUUC-Tru-118570	Takifugu rubripes	45.42	4.00e-135	476.00
IUUC-Tni-120836	Tetraodon nigroviridis	45.12	2.00e-128	453.00
IUUC-Tca-121479	Theobroma cacao	46.07	5.00e-138	485.00
IUUC-Tre-121909	Trichoderma reesei	58.24	0.00e+00	1196.00
IUUC-Tvi-122370	Trichoderma virens	57.04	0.00e+00	1194.00
IUUC-Tae-125214	Triticum aestivum	37.50	5.00e-134	471.00
IUUC-Tme-127172	Tuber melanosporum	73.93	0.00e+00	998.00
IUUC-Ttr-129253	Tursiops truncatus	46.65	6.00e-134	472.00
IUUC-Uma-129355	Ustilago maydis	58.13	0.00e+00	626.00
IUUC-Vda-129886	Verticillium dahliae	57.59	0.00e+00	1183.00
IUUC-Vpa-130708	Vicugna pacos	46.65	9.00e-134	471.00
IUUC-Vvi-131078	Vitis vinifera	46.18	3.00e-138	486.00
IUUC-Xtr-132123	Xenopus tropicalis	44.93	9.00e-128	451.00
IUUC-Xma-133869	Xiphophorus maculatus	46.46	2.00e-134	473.00
IUUC-Yli-134657	Yarrowia lipolytica	62.79	0.00e+00	823.00
IUUC-Zma-135570	Zea mays	43.99	1.00e-139	490.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence