iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-116132

Ensembl Protein ID

ENSSSCP00000011653.2

UniProt Accession

F1S4N3; F1S4N3_PIG

Genbank Protein ID

ENSSSCP00000011653

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU986276

Gene Name

KDM5B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000010928.2	ENSSSCT00000011960.2	ENSSSCP00000011653.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.50e-13	50.9	310	356

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g++++  l+ C+ C++ +H  Cl ++   ++p+ + w CpkC 
   Q: 310  VCLLCGSGSDED-RLLLCDGCDDSYHTFCLIPP-LHDVPKGD-WRCPKCL 356
           8*********88.6*******************.*******7.******5 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

TVAAGTFHWG PIPXPXTRWP GPLGEFLPPP ECPVFEPSWE FADPFAFIHK IRPIAEQTGI 60
CKVRPPPDWQ PPFACDVDKL HFTPRIQRLN ELEAQTRVKL NFLDQIAKYW ELQGSTLKIP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGTCGCAG CAGGTACTTT TCATTGGGGT CCAAGAGCGT GACCAGCGGC CGGCGGGATC 60
TCCGCAGGAG GTAGGAGCCC AGAGCTAGGC CAAACAGACT CAGCAGCCCC ACCCCCAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0060763--P:mammary duct terminal end bud growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0010628--P:positive regulation of gene expression
GO:0033601--P:positive regulation of mammary gland epithelial cell proliferation
GO:0009791--P:post-embryonic development
GO:2000864--P:regulation of estradiol secretion
GO:0007338--P:single fertilization
GO:0061038--P:uterus morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000552	Aegilops tauschii	32.35	4.00e-101	363.00
IUUC-Aml-001963	Ailuropoda melanoleuca	95.15	0.00e+00	2367.00
IUUC-Atr-002595	Amborella trichopoda	33.60	7.00e-119	422.00
IUUC-Apl-003770	Anas platyrhynchos	85.14	0.00e+00	2144.00
IUUC-Aca-004867	Anolis carolinensis	82.48	0.00e+00	2187.00
IUUC-Ame-010620	Astyanax mexicanus	68.87	0.00e+00	1817.00
IUUC-Bta-012733	Bos taurus	94.86	0.00e+00	2372.00
IUUC-Bdi-014050	Brachypodium distachyon	30.96	2.00e-120	427.00
IUUC-Bol-015336	Brassica oleracea	36.45	2.00e-14	75.50
IUUC-Cja-019050	Callithrix jacchus	94.89	0.00e+00	2455.00
IUUC-Cfa-021015	Canis familiaris	95.31	0.00e+00	2359.00
IUUC-Cpo-022340	Cavia porcellus	94.10	0.00e+00	2315.00
IUUC-Csa-023441	Chlorocebus sabaeus	95.45	0.00e+00	2452.00
IUUC-Cho-024823	Choloepus hoffmanni	97.00	0.00e+00	1688.00
IUUC-Cgl-026613	Colletotrichum gloeosporioides	29.90	1.00e-107	385.00
IUUC-Cne-026851	Cryptococcus neoformans	29.40	2.00e-114	407.00
IUUC-Dre-027707	Danio rerio	66.64	0.00e+00	1731.00
IUUC-Dno-028978	Dasypus novemcinctus	94.50	0.00e+00	2429.00
IUUC-Dor-030854	Dipodomys ordii	82.88	0.00e+00	1523.00
IUUC-Ete-032760	Echinops telfairi	88.53	0.00e+00	1649.00
IUUC-Eca-034370	Equus caballus	95.72	0.00e+00	2310.00
IUUC-Eeu-035012	Erinaceus europaeus	78.30	0.00e+00	1822.00
IUUC-Fca-035494	Felis catus	95.56	0.00e+00	2350.00
IUUC-Fal-037631	Ficedula albicollis	84.02	0.00e+00	2121.00
IUUC-Gmo-039522	Gadus morhua	62.30	0.00e+00	1592.00
IUUC-Ggr-039929	Gaeumannomyces graminis	27.97	2.00e-102	368.00
IUUC-Gga-040802	Gallus gallus	85.42	0.00e+00	2243.00
IUUC-Gac-041563	Gasterosteus aculeatus	66.36	0.00e+00	1715.00
IUUC-Gma-042675	Glycine max	33.50	3.00e-102	367.00
IUUC-Ggo-044856	Gorilla gorilla	74.68	0.00e+00	1763.00
IUUC-Hsa-045888	Homo sapiens	92.68	0.00e+00	2453.00
IUUC-Hvu-047583	Hordeum vulgare	43.04	8.00e-16	79.00
IUUC-Itr-048297	Ictidomys tridecemlineatus	94.98	0.00e+00	2406.00
IUUC-Kpa-049245	Komagataella pastoris	21.14	2.00e-30	128.00
IUUC-Lch-050483	Latimeria chalumnae	70.05	0.00e+00	1866.00
IUUC-Lpe-051537	Leersia perrieri	31.68	6.00e-92	332.00
IUUC-Loc-052550	Lepisosteus oculatus	75.12	0.00e+00	1934.00
IUUC-Laf-053761	Loxodonta africana	92.89	0.00e+00	2308.00
IUUC-Mcc-055505	Macaca mulatta	92.83	0.00e+00	2458.00
IUUC-Mpo-057317	Magnaporthe poae	33.33	2.00e-103	370.00
IUUC-Mga-059358	Meleagris gallopavo	85.09	0.00e+00	2143.00
IUUC-Mmr-060863	Microcebus murinus	94.83	0.00e+00	2426.00
IUUC-Mdo-061957	Monodelphis domestica	89.00	0.00e+00	2340.00
IUUC-Mmu-063944	Mus musculus	93.18	0.00e+00	2355.00
IUUC-Mac-065069	Musa acuminata	36.04	2.00e-08	56.20
IUUC-Mpu-066719	Mustela putorius furo	95.13	0.00e+00	2433.00
IUUC-Mlu-068086	Myotis lucifugus	90.55	0.00e+00	2221.00
IUUC-Nle-069256	Nomascus leucogenys	91.67	0.00e+00	2414.00
IUUC-Opr-071002	Ochotona princeps	50.96	0.00e+00	1257.00
IUUC-Ont-071756	Oreochromis niloticus	66.85	0.00e+00	1724.00
IUUC-Oan-073568	Ornithorhynchus anatinus	89.82	0.00e+00	2339.00
IUUC-Ocu-073961	Oryctolagus cuniculus	93.63	0.00e+00	2384.00
IUUC-Oba-075388	Oryza barthii	27.21	2.00e-80	294.00
IUUC-Obr-076296	Oryza brachyantha	39.55	6.00e-88	320.00
IUUC-Ogl-077886	Oryza glaberrima	38.83	1.00e-16	82.00
IUUC-Ogu-079040	Oryza glumaepatula	27.02	2.00e-80	294.00
IUUC-Olo-080668	Oryza longistaminata	38.83	3.00e-16	81.60
IUUC-Ome-081764	Oryza meridionalis	29.22	2.00e-98	354.00
IUUC-Oni-083012	Oryza nivara	26.92	1.00e-79	292.00
IUUC-Opu-083164	Oryza punctata	32.11	3.00e-89	323.00
IUUC-Oru-084630	Oryza rufipogon	27.06	8.00e-81	296.00
IUUC-Osa-085487	Oryza sativa	38.83	1.00e-16	82.00
IUUC-Ola-086448	Oryzias latipes	66.59	0.00e+00	1716.00
IUUC-Oga-088501	Otolemur garnettii	89.75	0.00e+00	1971.00
IUUC-Oar-090162	Ovis aries	94.06	0.00e+00	2346.00
IUUC-Ptr-090816	Pan troglodytes	92.83	0.00e+00	2462.00
IUUC-Pan-092764	Papio anubis	95.45	0.00e+00	2451.00
IUUC-Psi-093918	Pelodiscus sinensis	84.47	0.00e+00	1927.00
IUUC-Pfo-096672	Poecilia formosa	67.32	0.00e+00	1714.00
IUUC-Pab-097854	Pongo abelii	92.03	0.00e+00	2162.00
IUUC-Pca-100241	Procavia capensis	89.14	0.00e+00	1387.00
IUUC-Pva-103035	Pteropus vampyrus	86.70	0.00e+00	2103.00
IUUC-Rno-105574	Rattus norvegicus	90.89	0.00e+00	2272.00
IUUC-Sce-106207	Saccharomyces cerevisiae	35.35	3.00e-73	269.00
IUUC-Sit-110534	Setaria italica	32.92	9.00e-101	362.00
IUUC-Sly-111298	Solanum lycopersicum	42.44	2.00e-102	367.00
IUUC-Sar-113477	Sorex araneus	91.27	0.00e+00	2306.00
IUUC-Tgu-117452	Taeniopygia guttata	84.80	0.00e+00	2122.00
IUUC-Tru-117561	Takifugu rubripes	65.10	0.00e+00	1696.00
IUUC-Tsy-119271	Tarsius syrichta	93.87	0.00e+00	1796.00
IUUC-Tni-119650	Tetraodon nigroviridis	66.72	0.00e+00	1713.00
IUUC-Tae-125894	Triticum aestivum	32.84	1.00e-102	368.00
IUUC-Tur-126632	Triticum urartu	32.47	2.00e-100	360.00
IUUC-Tbe-127890	Tupaia belangeri	86.82	0.00e+00	1150.00
IUUC-Ttr-128546	Tursiops truncatus	91.78	0.00e+00	2032.00
IUUC-Vpa-130432	Vicugna pacos	92.80	0.00e+00	1465.00
IUUC-Xtr-132008	Xenopus tropicalis	74.57	0.00e+00	1922.00
IUUC-Xma-133571	Xiphophorus maculatus	67.08	0.00e+00	1726.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence