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Tag Content
UUCD2 ID IUUC-Ptr-091034
UUCD1 version UUC-PaT-00914
Ensembl Protein ID ENSPTRP00000051666.2
UniProt Accession H2R8I3; H2R8I3_PANTR
Genbank Protein ID ENSPTRP00000051666
Protein Name Uncharacterized protein
Genbank Nucleotide ID AACZ03101154
Gene Name HERC2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPTRG00000006835.4 ENSPTRT00000012625.3 ENSPTRP00000051666.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 1.60e-86 290.7 4261 4590
Active Site
Position(s) Description Evidence
4559 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 7    krlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp.....ehlklFeflGrllgkalqdgrll 88
           ++++v+fvgE++ d+gG  +e +a++++elqn  ++l+  ++n++ +   n+d +l +p      h ++F+flG+llg+a+++g +l
   Q: 4261 RVWKVKFVGESVDDCGGGYSESIAEICEELQNGLTPLLIVTPNGRDESGANRDCYLLSPaarapVHSSMFRFLGVLLGIAIRTGSPL 4347
           4566****************************************************99999999*********************** PP
   S: 89   dlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvk 175
            l+l+++++k+l g +l++ dl+evd++++  l++i++n+ ++ e +++ l f+     +++++ +++  +++++++t +N+ eYv+
   Q: 4348 SLNLAEPVWKQLAGMSLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFT-----VPSASGQDIQLSSKHTHITLDNRAEYVR 4429
           ***************************************9999999999***99.....788999999******************* PP
   S: 176  lvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerk 262
           l ++yrl+e ++eqv+a+reG+ +v+p  llslFt  ele+++cG+++i ++ lk+ ++ykg ++++ + iqwFwev+e+fs++er+
   Q: 4430 LAINYRLHE-FDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKG-IEPSASLIQWFWEVMESFSNTERS 4514
           *********.**************************************************77.************************ PP
   S: 263  afLqFvTgssrlPlgGfaelkprlfvirk....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
            fL+Fv+g+ rlP + +a+++ r fvi+     +  d+ lP+s TCf++LkLP+Ys k++l+ekL yAi+ +k++++
   Q: 4515 LFLRFVWGRTRLP-RTIADFRGRDFVIQVldkyNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDT 4590
           *************.8*************999988888***********************************99875 PP
   
Organism Pan troglodytes
Protein Sequence
(Fasta)
MPSESFCLAA QARLDSKWLK TDIQLAFTRD GLCGLWNEMV KDGEIVYTGT ESTQNGELPP 60
RKDDSVEPSG TKKEDLNDKE KKDEEETPAP IYRAKSILDS WVWGKQPDVN ELKECLSVLV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ptr-091034|E3,HECT|Pan troglodytes
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGCGGCTCTT GGGAGGCTGC GTCCGCGCGC CGGCGGGGCG AGGCGGCCTG GCCCTGCGCG 60
TCAGGTCCTG GCCTGGGGCA CCTGGGCGGC CGGTGGCGGG GGCGGTACGG GCGCGGGGCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ptr-091034|E3,HECT|Pan troglodytes
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR004939--APC_su10/DOC_dom
IPR021097--CPH_domain
IPR001199--Cyt_B5-like_heme/steroid-bd
IPR008979--Galactose-bd-like
IPR000569--HECT_dom
IPR010606--Mib_Herc2
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
IPR014722--Rib_L2_dom2
IPR000433--Znf_ZZ
PROSITE

PS50255--CYTOCHROME_B5_2
PS51284--DOC
PS50237--HECT
PS51416--MIB_HERC2
PS00626--RCC1_2
PS50012--RCC1_3
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2
Pfam

PF03256--ANAPC10
PF11515--Cul7
PF00173--Cyt-b5
PF00632--HECT
PF06701--MIB_HERC2
PF00415--RCC1
PF00569--ZZ
PRINTS

PR00633--RCCNDNSATION
SMART

SM01337--APC10
SM01117--Cyt-b5
SM00119--HECTc
SM00291--ZnF_ZZ
Gene Ontology

GO:0005743--C:mitochondrial inner membrane
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0007283--P:spermatogenesis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002112 Ailuropoda melanoleuca 86.48 0.00e+00 4470.00
IUUC-Atr-003065 Amborella trichopoda 35.59 3.00e-51 197.00
IUUC-Apl-003983 Anas platyrhynchos 82.12 0.00e+00 4318.00
IUUC-Aca-004300 Anolis carolinensis 80.59 0.00e+00 4176.00
IUUC-Aly-006441 Arabidopsis lyrata 34.15 8.00e-45 175.00
IUUC-Ame-010621 Astyanax mexicanus 76.89 0.00e+00 4773.00
IUUC-Bta-013067 Bos taurus 85.31 0.00e+00 4335.00
IUUC-Bdi-014093 Brachypodium distachyon 33.25 2.00e-49 191.00
IUUC-Bol-015203 Brassica oleracea 34.55 1.00e-52 202.00
IUUC-Bra-016737 Brassica rapa 34.55 3.00e-48 187.00
IUUC-Cja-019687 Callithrix jacchus 88.31 0.00e+00 4450.00
IUUC-Cfa-020672 Canis familiaris 86.22 0.00e+00 4437.00
IUUC-Cpo-021819 Cavia porcellus 83.06 0.00e+00 4215.00
IUUC-Csa-023817 Chlorocebus sabaeus 89.32 0.00e+00 4544.00
IUUC-Cho-024387 Choloepus hoffmanni 95.76 0.00e+00 1930.00
IUUC-Cin-025709 Ciona intestinalis 67.65 0.00e+00 1071.00
IUUC-Csv-026336 Ciona savignyi 67.56 0.00e+00 1096.00
IUUC-Dre-027717 Danio rerio 76.22 0.00e+00 4714.00
IUUC-Dno-029296 Dasypus novemcinctus 85.74 0.00e+00 5447.00
IUUC-Dor-030979 Dipodomys ordii 91.41 0.00e+00 2927.00
IUUC-Dme-032171 Drosophila melanogaster 70.52 0.00e+00 1111.00
IUUC-Ete-032687 Echinops telfairi 82.48 0.00e+00 2001.00
IUUC-Eca-034046 Equus caballus 85.50 0.00e+00 4358.00
IUUC-Eeu-034859 Erinaceus europaeus 82.87 0.00e+00 1926.00
IUUC-Fca-036262 Felis catus 86.50 0.00e+00 4444.00
IUUC-Fal-037562 Ficedula albicollis 81.68 0.00e+00 4233.00
IUUC-Gmo-039054 Gadus morhua 86.16 0.00e+00 1088.00
IUUC-Gga-040359 Gallus gallus 82.00 0.00e+00 4299.00
IUUC-Gac-041879 Gasterosteus aculeatus 90.57 0.00e+00 1041.00
IUUC-Ggo-044692 Gorilla gorilla 84.30 0.00e+00 2701.00
IUUC-Hsa-045995 Homo sapiens 90.19 0.00e+00 4593.00
IUUC-Hvu-047529 Hordeum vulgare 35.65 3.00e-49 190.00
IUUC-Itr-048553 Ictidomys tridecemlineatus 96.38 0.00e+00 2454.00
IUUC-Lch-049808 Latimeria chalumnae 67.10 0.00e+00 1725.00
IUUC-Lpe-051482 Leersia perrieri 33.94 4.00e-46 180.00
IUUC-Loc-052685 Lepisosteus oculatus 76.88 0.00e+00 3982.00
IUUC-Laf-053372 Loxodonta africana 85.27 0.00e+00 4385.00
IUUC-Mcc-054693 Macaca mulatta 89.43 0.00e+00 4553.00
IUUC-Meu-056660 Macropus eugenii 95.57 0.00e+00 1517.00
IUUC-Mga-059371 Meleagris gallopavo 81.77 0.00e+00 4282.00
IUUC-Mmr-060787 Microcebus murinus 88.27 0.00e+00 4539.00
IUUC-Mdo-062518 Monodelphis domestica 86.66 0.00e+00 5427.00
IUUC-Mmu-063690 Mus musculus 85.31 0.00e+00 4405.00
IUUC-Mpu-066478 Mustela putorius furo 85.58 0.00e+00 4363.00
IUUC-Mlu-067596 Myotis lucifugus 81.77 0.00e+00 3976.00
IUUC-Nle-069445 Nomascus leucogenys 97.09 0.00e+00 1134.00
IUUC-Opr-070990 Ochotona princeps 98.15 0.00e+00 1573.00
IUUC-Ont-072285 Oreochromis niloticus 76.88 0.00e+00 4699.00
IUUC-Oan-072721 Ornithorhynchus anatinus 73.04 0.00e+00 2788.00
IUUC-Ocu-074273 Oryctolagus cuniculus 86.94 0.00e+00 4454.00
IUUC-Oba-075573 Oryza barthii 33.68 1.00e-45 179.00
IUUC-Obr-076107 Oryza brachyantha 33.77 3.00e-50 193.00
IUUC-Ogl-077193 Oryza glaberrima 33.68 9.00e-46 179.00
IUUC-Ogu-078817 Oryza glumaepatula 33.68 9.00e-46 179.00
IUUC-Oin-079609 Oryza indica 32.75 2.00e-49 191.00
IUUC-Olo-080629 Oryza longistaminata 33.68 1.00e-45 178.00
IUUC-Ome-081686 Oryza meridionalis 33.68 4.00e-46 180.00
IUUC-Opu-084137 Oryza punctata 33.94 2.00e-46 181.00
IUUC-Oru-085013 Oryza rufipogon 33.68 9.00e-46 179.00
IUUC-Osa-085597 Oryza sativa 33.68 9.00e-46 179.00
IUUC-Ola-087346 Oryzias latipes 92.39 0.00e+00 1194.00
IUUC-Oga-088742 Otolemur garnettii 86.10 0.00e+00 4408.00
IUUC-Oar-090093 Ovis aries 85.57 0.00e+00 4337.00
IUUC-Pan-092783 Papio anubis 88.70 0.00e+00 4534.00
IUUC-Psi-094027 Pelodiscus sinensis 81.40 0.00e+00 4283.00
IUUC-Pfo-096208 Poecilia formosa 76.41 0.00e+00 3705.00
IUUC-Pab-097681 Pongo abelii 96.37 0.00e+00 1834.00
IUUC-Pca-100705 Procavia capensis 95.36 0.00e+00 1173.00
IUUC-Pva-103147 Pteropus vampyrus 93.36 0.00e+00 1520.00
IUUC-Rno-105458 Rattus norvegicus 85.60 0.00e+00 4398.00
IUUC-Sha-106959 Sarcophilus harrisii 77.51 0.00e+00 3947.00
IUUC-Sit-109917 Setaria italica 36.47 2.00e-48 187.00
IUUC-Sly-110961 Solanum lycopersicum 34.35 3.00e-53 203.00
IUUC-Sar-113532 Sorex araneus 87.65 0.00e+00 1536.00
IUUC-Sbi-114352 Sorghum bicolor 32.39 8.00e-50 192.00
IUUC-Ssc-115337 Sus scrofa 90.54 0.00e+00 1790.00
IUUC-Tgu-116789 Taeniopygia guttata 81.75 0.00e+00 4277.00
IUUC-Tru-118129 Takifugu rubripes 76.26 0.00e+00 4735.00
IUUC-Tsy-119302 Tarsius syrichta 84.96 0.00e+00 1273.00
IUUC-Tni-120374 Tetraodon nigroviridis 74.58 0.00e+00 4582.00
IUUC-Tca-121094 Theobroma cacao 35.31 6.00e-54 206.00
IUUC-Tae-124157 Triticum aestivum 33.51 9.00e-50 192.00
IUUC-Tur-126300 Triticum urartu 35.29 1.00e-49 192.00
IUUC-Tbe-128137 Tupaia belangeri 87.13 0.00e+00 1779.00
IUUC-Ttr-128273 Tursiops truncatus 84.14 0.00e+00 4032.00
IUUC-Vpa-130471 Vicugna pacos 90.44 0.00e+00 1098.00
IUUC-Xtr-132185 Xenopus tropicalis 78.20 0.00e+00 4815.00
IUUC-Xma-133233 Xiphophorus maculatus 76.85 0.00e+00 4689.00
Created Date 25-Jun-2017

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