iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-120886

Ensembl Protein ID

ENSTNIP00000020109.1

UniProt Accession

H3DHW5; H3DHW5_TETNG

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000016986.1	ENSTNIT00000020340.1	ENSTNIP00000020109.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.80e-16	58.4	96	152

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++++lydy+a ++d+L+++kG++ ++i  ++++++W+++ + ++g +G +P+n+v+ ++
   Q: 96   LFIALYDYDARTEDDLSFRKGEKFHII--NNTEGDWWEARSLDTGNSGYIPSNYVAPVD 152
           5789***********************..8999**********************9987 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MGCACCKQKK PANGTDPSPS NPDGGLSAAL TQGRYGPDPT QTIPDYNKGF SSSAIFPSIN 60
THQRPGGLTG TTPVPATIAV PRCVCVCANA GGGVTLFIAL YDYDARTEDD LSFRKGEKFH 120

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Nucleotide Sequence
(Fasta)

ATGGGGTGTG CCTGTTGCAA GCAGAAAAAG CCTGCTAAAG CAGCAGCAAC ATCAGCAGCA 60
GCAGACGGTA CCGACCCGTC TCCTAGCAAC CCAGATGGAG GGCTGTCTGC GGCCTTGACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0048246--P:macrophage chemotaxis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011816	Astyanax mexicanus	82.45	0.00e+00	920.00
IUUC-Bdi-014324	Brachypodium distachyon	35.82	3.00e-23	103.00
IUUC-Dre-028216	Danio rerio	84.55	0.00e+00	939.00
IUUC-Fal-036786	Ficedula albicollis	84.13	0.00e+00	879.00
IUUC-Gac-041918	Gasterosteus aculeatus	90.13	0.00e+00	990.00
IUUC-Lpe-051166	Leersia perrieri	34.65	7.00e-23	102.00
IUUC-Loc-052620	Lepisosteus oculatus	81.11	0.00e+00	918.00
IUUC-Meu-056155	Macropus eugenii	77.75	0.00e+00	725.00
IUUC-Ont-072409	Oreochromis niloticus	87.27	0.00e+00	943.00
IUUC-Oba-075994	Oryza barthii	34.16	5.00e-21	96.30
IUUC-Ogl-077331	Oryza glaberrima	35.15	5.00e-24	106.00
IUUC-Ogu-078962	Oryza glumaepatula	35.15	6.00e-24	105.00
IUUC-Oin-079172	Oryza indica	35.15	5.00e-24	106.00
IUUC-Olo-080286	Oryza longistaminata	35.15	5.00e-24	106.00
IUUC-Ome-081400	Oryza meridionalis	35.15	4.00e-24	106.00
IUUC-Oru-084741	Oryza rufipogon	35.15	5.00e-24	106.00
IUUC-Osa-085779	Oryza sativa	35.10	4.00e-24	106.00
IUUC-Ola-086657	Oryzias latipes	88.27	0.00e+00	972.00
IUUC-Pfo-096519	Poecilia formosa	83.30	0.00e+00	899.00
IUUC-Ppe-102072	Prunus persica	33.08	6.00e-25	109.00
IUUC-Tru-117916	Takifugu rubripes	92.66	0.00e+00	996.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence