iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074707

UUCD1 version

UUC-OrC-00417

Ensembl Protein ID

ENSOCUP00000009840.2

UniProt Accession

G1T1B1; G1T1B1_RABIT

Protein Name

Uncharacterized protein

Gene Name

EP300

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000011434.3	ENSOCUT00000011440.3	ENSOCUP00000009840.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	95.58	0.00e+00	1896.00	IUUC-Hsa-046884

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MAENVVEPGP PSAKRPKLSS PALSASASDG TDFGSLFDLE HDLPDELINS TELGLTNGGD 60
ISQLQTSLGI VQDAASKHKQ LSELLRSGSS PNLNMGVGGP GQVMASQAQQ NSPGLGLINS 120

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Nucleotide Sequence
(Fasta)

GCCGGCCGCC GCGCGATGTG AGGCGGCGGC GGCGCCAGCC TGGCTCTCGG CTCGGGCGAG 60
CTTCCCGCGG CCATTAGGGG CCGGTGCGGC GGCGGCGGCG GCGGCAGGAG GAGGGCTGGG 120

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Sequence Source

Ensembl

Keyword

KW-0012--Acyltransferase
KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR031162--CBP_P300_HAT
IPR013178--Histone_AcTrfase_Rtt109/CBP
IPR003101--KIX_dom
IPR009110--Nuc_rcpt_coact
IPR014744--Nuc_rcpt_coact_CREBbp
IPR010303--RING_CBP-p300
IPR000197--Znf_TAZ
IPR000433--Znf_ZZ

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51727--CBP_P300_HAT
PS50952--KIX
PS50134--ZF_TAZ
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00439--Bromodomain
PF09030--Creb_binding
PF06001--DUF902
PF08214--HAT_KAT11
PF02172--KIX
PF02135--zf-TAZ
PF00569--ZZ

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM01250--KAT11
SM00551--ZnF_TAZ
SM00291--ZnF_ZZ

Gene Ontology

GO:0005829--C:cytosol
GO:0000123--C:histone acetyltransferase complex
GO:0005667--C:transcription factor complex
GO:0031490--F:chromatin DNA binding
GO:0003684--F:damaged DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0004468--F:lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0097157--F:pre-mRNA intronic binding
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0001228--F:transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0009887--P:animal organ morphogenesis
GO:0030183--P:B cell differentiation
GO:0034644--P:cellular response to UV
GO:0007623--P:circadian rhythm
GO:0045444--P:fat cell differentiation
GO:0007507--P:heart development
GO:0043969--P:histone H2B acetylation
GO:0043967--P:histone H4 acetylation
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0030324--P:lung development
GO:0010742--P:macrophage derived foam cell differentiation
GO:0035855--P:megakaryocyte development
GO:0018076--P:N-terminal peptidyl-lysine acetylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030220--P:platelet formation
GO:0043923--P:positive regulation by host of viral transcription
GO:0032092--P:positive regulation of protein binding
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0006990--P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
GO:0050821--P:protein stabilization
GO:0060765--P:regulation of androgen receptor signaling pathway
GO:0090043--P:regulation of tubulin deacetylation
GO:0043627--P:response to estrogen
GO:0001666--P:response to hypoxia
GO:0007519--P:skeletal muscle tissue development
GO:0001756--P:somitogenesis

KEGG

ocu:100354135

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001156	Aegilops tauschii	37.66	8.00e-68	253.00
IUUC-Aml-002027	Ailuropoda melanoleuca	95.25	0.00e+00	1891.00
IUUC-Apl-003917	Anas platyrhynchos	80.16	0.00e+00	1435.00
IUUC-Aca-005040	Anolis carolinensis	80.38	0.00e+00	1712.00
IUUC-Ath-007233	Arabidopsis thaliana	38.38	3.00e-74	274.00
IUUC-Ame-011395	Astyanax mexicanus	85.65	0.00e+00	1464.00
IUUC-Bta-012649	Bos taurus	94.44	0.00e+00	2014.00
IUUC-Bdi-014481	Brachypodium distachyon	33.43	1.00e-91	332.00
IUUC-Bol-016000	Brassica oleracea	39.04	4.00e-74	273.00
IUUC-Bra-018090	Brassica rapa	38.94	3.00e-74	274.00
IUUC-Cel-018691	Caenorhabditis elegans	50.55	0.00e+00	845.00
IUUC-Cja-019649	Callithrix jacchus	91.51	0.00e+00	3314.00
IUUC-Cfa-020764	Canis familiaris	96.85	0.00e+00	1791.00
IUUC-Cpo-022345	Cavia porcellus	89.01	0.00e+00	3311.00
IUUC-Cre-022852	Chlamydomonas reinhardtii	35.09	6.00e-66	246.00
IUUC-Csa-023866	Chlorocebus sabaeus	96.22	0.00e+00	1924.00
IUUC-Cho-024951	Choloepus hoffmanni	95.56	0.00e+00	1217.00
IUUC-Cin-025624	Ciona intestinalis	61.41	0.00e+00	1057.00
IUUC-Csv-026122	Ciona savignyi	65.28	0.00e+00	679.00
IUUC-Dre-028500	Danio rerio	79.04	0.00e+00	1461.00
IUUC-Dno-029638	Dasypus novemcinctus	79.87	0.00e+00	1442.00
IUUC-Dor-030287	Dipodomys ordii	92.80	0.00e+00	1187.00
IUUC-Dme-031716	Drosophila melanogaster	73.39	0.00e+00	780.00
IUUC-Ete-032979	Echinops telfairi	90.51	0.00e+00	1918.00
IUUC-Eca-034048	Equus caballus	97.10	0.00e+00	1905.00
IUUC-Eeu-035154	Erinaceus europaeus	79.73	0.00e+00	1332.00
IUUC-Fca-035891	Felis catus	96.78	0.00e+00	1898.00
IUUC-Fal-037585	Ficedula albicollis	84.76	0.00e+00	1761.00
IUUC-Gmo-039348	Gadus morhua	87.21	0.00e+00	1441.00
IUUC-Gga-040916	Gallus gallus	83.62	0.00e+00	1880.00
IUUC-Gac-041642	Gasterosteus aculeatus	87.32	0.00e+00	1414.00
IUUC-Ggo-045189	Gorilla gorilla	95.80	0.00e+00	2033.00
IUUC-Hsa-046884	Homo sapiens	95.52	0.00e+00	2033.00
IUUC-Hvu-047619	Hordeum vulgare	37.66	7.00e-68	253.00
IUUC-Itr-048564	Ictidomys tridecemlineatus	97.84	0.00e+00	1879.00
IUUC-Loc-052536	Lepisosteus oculatus	86.55	0.00e+00	1433.00
IUUC-Laf-054423	Loxodonta africana	96.22	0.00e+00	2014.00
IUUC-Mcc-054847	Macaca mulatta	95.73	0.00e+00	2043.00
IUUC-Meu-056217	Macropus eugenii	85.76	0.00e+00	1824.00
IUUC-Mtr-058740	Medicago truncatula	38.27	1.00e-67	252.00
IUUC-Mga-059250	Meleagris gallopavo	79.89	0.00e+00	1903.00
IUUC-Mmr-061496	Microcebus murinus	97.18	0.00e+00	1941.00
IUUC-Mdo-062478	Monodelphis domestica	86.93	0.00e+00	1937.00
IUUC-Mmu-063456	Mus musculus	95.25	0.00e+00	1899.00
IUUC-Mac-064767	Musa acuminata	39.85	1.00e-75	278.00
IUUC-Mpu-065963	Mustela putorius furo	93.88	0.00e+00	1875.00
IUUC-Mlu-067185	Myotis lucifugus	96.06	0.00e+00	1894.00
IUUC-Ncr-068795	Neurospora crassa	37.97	1.00e-13	70.90
IUUC-Nle-069907	Nomascus leucogenys	96.09	0.00e+00	1867.00
IUUC-Opr-070324	Ochotona princeps	90.78	0.00e+00	1223.00
IUUC-Ont-072211	Oreochromis niloticus	78.30	0.00e+00	1439.00
IUUC-Oan-073723	Ornithorhynchus anatinus	88.55	0.00e+00	1844.00
IUUC-Oba-075590	Oryza barthii	33.52	3.00e-103	370.00
IUUC-Ogu-078580	Oryza glumaepatula	33.38	2.00e-103	370.00
IUUC-Oin-079283	Oryza indica	38.83	2.00e-73	271.00
IUUC-Olo-080969	Oryza longistaminata	38.83	2.00e-73	271.00
IUUC-Ome-081615	Oryza meridionalis	33.52	4.00e-103	370.00
IUUC-Oni-082636	Oryza nivara	33.52	3.00e-103	370.00
IUUC-Opu-084073	Oryza punctata	32.97	7.00e-100	359.00
IUUC-Oru-084994	Oryza rufipogon	33.52	3.00e-103	370.00
IUUC-Osa-085860	Oryza sativa	42.26	1.00e-62	235.00
IUUC-Ola-086899	Oryzias latipes	77.53	0.00e+00	1387.00
IUUC-Olu-087701	Ostreococcus lucimarinus	34.95	3.00e-61	230.00
IUUC-Oga-088700	Otolemur garnettii	96.01	0.00e+00	2031.00
IUUC-Oar-089787	Ovis aries	91.92	0.00e+00	2007.00
IUUC-Ptr-091620	Pan troglodytes	94.77	0.00e+00	2034.00
IUUC-Pan-092166	Papio anubis	94.42	0.00e+00	2067.00
IUUC-Psi-093992	Pelodiscus sinensis	86.54	0.00e+00	1862.00
IUUC-Pma-094328	Petromyzon marinus	85.93	0.00e+00	992.00
IUUC-Ppa-095569	Physcomitrella patens	37.84	3.00e-71	263.00
IUUC-Pfo-097342	Poecilia formosa	84.76	0.00e+00	1380.00
IUUC-Pab-098235	Pongo abelii	94.85	0.00e+00	1917.00
IUUC-Pop-098947	Populus trichocarpa	40.25	6.00e-74	273.00
IUUC-Pca-100780	Procavia capensis	87.88	0.00e+00	1448.00
IUUC-Ppe-101498	Prunus persica	37.19	2.00e-67	251.00
IUUC-Pva-103071	Pteropus vampyrus	95.80	0.00e+00	2168.00
IUUC-Sha-106736	Sarcophilus harrisii	90.70	0.00e+00	1655.00
IUUC-Smo-109420	Selaginella moellendorffii	38.27	2.00e-71	265.00
IUUC-Sit-110128	Setaria italica	38.94	2.00e-72	268.00
IUUC-Stu-112845	Solanum tuberosum	37.34	1.00e-64	241.00
IUUC-Sar-113162	Sorex araneus	94.51	0.00e+00	847.00
IUUC-Sbi-114827	Sorghum bicolor	39.59	9.00e-74	272.00
IUUC-Ssc-116077	Sus scrofa	96.34	0.00e+00	2113.00
IUUC-Tgu-116872	Taeniopygia guttata	85.27	0.00e+00	1790.00
IUUC-Tru-118047	Takifugu rubripes	64.99	0.00e+00	1748.00
IUUC-Tsy-119451	Tarsius syrichta	94.27	0.00e+00	1313.00
IUUC-Tca-121835	Theobroma cacao	39.39	2.00e-73	271.00
IUUC-Tvi-122536	Trichoderma virens	43.04	2.00e-15	77.00
IUUC-Tae-124383	Triticum aestivum	38.73	1.00e-68	255.00
IUUC-Tur-126284	Triticum urartu	37.91	2.00e-68	255.00
IUUC-Tbe-127772	Tupaia belangeri	87.39	0.00e+00	1362.00
IUUC-Ttr-128325	Tursiops truncatus	96.61	0.00e+00	1455.00
IUUC-Vpa-130766	Vicugna pacos	92.78	0.00e+00	1304.00
IUUC-Xtr-131854	Xenopus tropicalis	81.46	0.00e+00	1648.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence