iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007545

UUCD1 version

UUC-ArT-01298

Ensembl Protein ID

AT4G02730.1

UniProt Accession

Q9SY00; WDR5B_ARATH

Genbank Protein ID

AAD15347.1; CAB77758.1; AEE82221.1; AAL27497.1; AAM65666.1; AAM78068.1

Protein Name

COMPASS-like H3K4 histone methylase component WDR5B

Genbank Nucleotide ID

AC004044; AL161495; CP002687; AF439825; AY088121; AY125558

Gene Name

WDR5B; At4g02730; T5J8.2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT4G02730	AT4G02730.1	AT4G02730.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-49	164.5	126	164
UBD/Beta-Prp	3.80e-72	243.9	41	331

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllk 37
           gHt+ v+c++f  +++l+vsGs D ti++W+++tg++++
   Q: 126  GHTNFVFCVNFnpPSNLIVSGSFDETIRIWEVKTGKCVR 164
           8***********766**********************97 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsfs 103
           g h++ i+cvkfs+d++lla++s d+t ++w++t+ +l+++++gh+++++++ +s+d+ +  ++s+D t+++wd +  ++c+ +l+gh++ v +++f+
   Q: 41   G-HTAAISCVKFSNDGNLLASASVDKTMILWSATNYSLIHRYEGHSSGISDLAWSSDSHYTCSASDDCTLRIWDARsPYECLKVLRGHTNFVFCVNFN 137
           3.6779999****************************************************************887479******************* PP
   S: 104  psgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsld 201
           p ++ +vsGs d+tir+w+++tg+c++ + + h+  +++v+++ dg+l+vs+s D+ +++Wd k g++l+tl  ++ ++v   +f++ngk+++ + ld
   Q: 138  PPSNLIVSGSFDETIRIWEVKTGKCVR-MIKAHSMPISSVHFNRDGSLIVSASHDGSCKIWDAKEGTCLKTLIDDKSPAVSFAKFSPNGKFILVATLD 234
           ***************************.********************************************998888999999************** PP
   S: 202  gtvklwdlqtgecvrtlnghtdnvksvrfs...pnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgse.dskvniwkl 294
           +t+kl ++ tg+ ++ ++ght+ v ++       n++++vsgs+D+ +++Wdl+ +++l+ l++h + visv+++ +++ +  +g   d++++iwk+
   Q: 235  STLKLSNYATGKFLKVYTGHTNKVFCITSAfsvTNGKYIVSGSEDNCVYLWDLQARNILQRLEGHTDAVISVSCHPVQNEISSSGNHlDKTIRIWKQ 331
           *************************997555699****************************************7777777777777********97 PP

Organism

Arabidopsis thaliana

Protein Sequence
(Fasta)

MPSGGNGTSN GVANANSTGN AGTSGNVPIY KPYRHLKTLE GHTAAISCVK FSNDGNLLAS 60
ASVDKTMILW SATNYSLIHR YEGHSSGISD LAWSSDSHYT CSASDDCTLR IWDARSPYEC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGAATGTAT ATATATGTAA CGGTGAGAGA TTCATTGAGA TCATCTCCAC TCTGCTAAAT 60
CCGACGAGAG ACGACGATGC CAAGCGGTGG TAACGGAACA AGTAACGGAG TCGCTAACGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex

KEGG

ath:AT4G02730

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000502	Aegilops tauschii	61.87	7.00e-106	375.00
IUUC-Atr-002924	Amborella trichopoda	69.28	2.00e-116	411.00
IUUC-Aly-005655	Arabidopsis lyrata	98.05	0.00e+00	628.00
IUUC-Bdi-014642	Brachypodium distachyon	65.13	1.00e-115	408.00
IUUC-Bol-015533	Brassica oleracea	90.45	1.00e-172	598.00
IUUC-Bra-017641	Brassica rapa	91.78	1.00e-170	591.00
IUUC-Gma-042658	Glycine max	71.38	2.00e-135	474.00
IUUC-Mtr-058429	Medicago truncatula	72.55	7.00e-125	439.00
IUUC-Oba-075292	Oryza barthii	63.64	3.00e-111	394.00
IUUC-Obr-076723	Oryza brachyantha	62.66	4.00e-111	393.00
IUUC-Ogl-077247	Oryza glaberrima	61.74	9.00e-112	395.00
IUUC-Ogu-078143	Oryza glumaepatula	60.95	2.00e-111	394.00
IUUC-Oin-080203	Oryza indica	60.95	6.00e-111	392.00
IUUC-Ome-082003	Oryza meridionalis	61.02	2.00e-111	394.00
IUUC-Oni-082216	Oryza nivara	60.95	6.00e-111	392.00
IUUC-Oru-084935	Oryza rufipogon	60.76	3.00e-111	394.00
IUUC-Osa-085444	Oryza sativa	60.95	2.00e-111	394.00
IUUC-Pop-099988	Populus trichocarpa	77.99	2.00e-150	524.00
IUUC-Ppe-101291	Prunus persica	73.42	4.00e-142	496.00
IUUC-Sit-110579	Setaria italica	64.05	2.00e-115	407.00
IUUC-Sly-111880	Solanum lycopersicum	72.13	1.00e-120	425.00
IUUC-Stu-112051	Solanum tuberosum	70.82	1.00e-119	422.00
IUUC-Sbi-113874	Sorghum bicolor	63.84	7.00e-116	409.00
IUUC-Tca-121324	Theobroma cacao	78.25	5.00e-146	509.00
IUUC-Tae-124942	Triticum aestivum	64.80	4.00e-115	407.00
IUUC-Vvi-131551	Vitis vinifera	71.02	2.00e-132	464.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence