iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045022

Ensembl Protein ID

ENSGGOP00000004443.2

UniProt Accession

G3QPF0; G3QPF0_GORGO

Protein Name

Uncharacterized protein

Gene Name

HDAC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000004525.2	ENSGGOT00000004553.2	ENSGGOP00000004443.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	99.41	0.00e+00	2311.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

NRGRGQASST MTSTGQDSTT TRQRRSRQNP QSPPQDSSVT SKRNIKKGAV PRSIPNLAEV 60
KKKGKMKKLG QAMEEDLIVG LQGMDLNLEA EALAGTGLVL DEQLNEFHCL WDDSFPEGPE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCAGTCCC CTGAGGAGCG GGGCTGGTTG AAACGCTAGG GGCGGGATCT GGCGGAGTGG 60
AAGGTACCGG TCCGGCCCGA TAAGGGGTGG AGTTAAGTGA ATCGTTAAGG GTGGAGTCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0016235--C:aggresome
GO:0030424--C:axon
GO:0005901--C:caveola
GO:0031252--C:cell leading edge
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030286--C:dynein complex
GO:0000118--C:histone deacetylase complex
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0001047--F:core promoter binding
GO:0004407--F:histone deacetylase activity
GO:0042903--F:tubulin deacetylase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0070301--P:cellular response to hydrogen peroxide
GO:0071218--P:cellular response to misfolded protein
GO:0048668--P:collateral sprouting
GO:0060997--P:dendritic spine morphogenesis
GO:0070846--P:Hsp90 deacetylation
GO:0032418--P:lysosome localization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0051646--P:mitochondrion localization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0045861--P:negative regulation of proteolysis
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0034983--P:peptidyl-lysine deacetylation
GO:0070845--P:polyubiquitinated misfolded protein transport
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0010634--P:positive regulation of epithelial cell migration
GO:1901300--P:positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0010870--P:positive regulation of receptor biosynthetic process
GO:0009967--P:positive regulation of signal transduction
GO:0043241--P:protein complex disassembly
GO:0000209--P:protein polyubiquitination
GO:0070201--P:regulation of establishment of protein localization
GO:0045598--P:regulation of fat cell differentiation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0031647--P:regulation of protein stability
GO:0010469--P:regulation of receptor activity
GO:0070848--P:response to growth factor
GO:0009636--P:response to toxic substance
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	41.61	3.00e-71	262.00
IUUC-Aml-002087	Ailuropoda melanoleuca	80.77	0.00e+00	1867.00
IUUC-Atr-002745	Amborella trichopoda	44.38	9.00e-81	294.00
IUUC-Aca-004303	Anolis carolinensis	50.79	0.00e+00	1163.00
IUUC-Aly-006432	Arabidopsis lyrata	42.01	7.00e-81	295.00
IUUC-Ath-007355	Arabidopsis thaliana	42.78	9.00e-85	307.00
IUUC-Ago-007972	Ashbya gossypii	41.65	3.00e-77	283.00
IUUC-Acl-008187	Aspergillus clavatus	45.99	7.00e-83	301.00
IUUC-Afl-008399	Aspergillus flavus	53.95	5.00e-44	171.00
IUUC-Afu-008954	Aspergillus fumigatus	41.27	5.00e-72	265.00
IUUC-Ani-009142	Aspergillus nidulans	42.89	4.00e-75	276.00
IUUC-Ang-009522	Aspergillus niger	37.32	2.00e-44	173.00
IUUC-Aor-010069	Aspergillus oryzae	46.48	2.00e-73	270.00
IUUC-Ate-010291	Aspergillus terreus	46.36	1.00e-81	297.00
IUUC-Ame-010780	Astyanax mexicanus	50.13	0.00e+00	771.00
IUUC-Bta-013052	Bos taurus	72.37	0.00e+00	1637.00
IUUC-Bci-013789	Botrytis cinerea	38.69	1.00e-76	281.00
IUUC-Bdi-014007	Brachypodium distachyon	44.38	2.00e-81	296.00
IUUC-Bol-015468	Brassica oleracea	43.98	8.00e-84	304.00
IUUC-Bra-016680	Brassica rapa	43.98	7.00e-84	305.00
IUUC-Cel-018220	Caenorhabditis elegans	38.46	2.00e-145	509.00
IUUC-Cja-019473	Callithrix jacchus	91.84	0.00e+00	2113.00
IUUC-Cfa-020263	Canis familiaris	84.67	0.00e+00	1566.00
IUUC-Cpo-021691	Cavia porcellus	78.96	0.00e+00	1811.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	55.56	6.00e-56	210.00
IUUC-Csa-024223	Chlorocebus sabaeus	98.32	0.00e+00	2273.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	42.24	1.00e-74	274.00
IUUC-Cne-026978	Cryptococcus neoformans	46.83	5.00e-85	308.00
IUUC-Dre-028820	Danio rerio	56.66	0.00e+00	892.00
IUUC-Dno-029160	Dasypus novemcinctus	68.74	0.00e+00	1558.00
IUUC-Dor-030859	Dipodomys ordii	71.58	0.00e+00	1656.00
IUUC-Dse-031186	Dothistroma septosporum	43.84	7.00e-76	278.00
IUUC-Dme-031963	Drosophila melanogaster	45.03	0.00e+00	669.00
IUUC-Ete-032279	Echinops telfairi	66.03	1.00e-151	530.00
IUUC-Eca-033842	Equus caballus	82.84	0.00e+00	1929.00
IUUC-Eeu-034487	Erinaceus europaeus	76.79	5.00e-153	535.00
IUUC-Fca-036430	Felis catus	75.53	0.00e+00	1672.00
IUUC-Fox-038067	Fusarium oxysporum	41.60	2.00e-74	273.00
IUUC-Fso-038263	Fusarium solani	41.86	1.00e-75	277.00
IUUC-Ggr-040062	Gaeumannomyces graminis	43.02	7.00e-75	275.00
IUUC-Gma-043738	Glycine max	49.53	2.00e-85	309.00
IUUC-Hsa-046904	Homo sapiens	99.41	0.00e+00	2312.00
IUUC-Hvu-047285	Hordeum vulgare	44.97	3.00e-82	298.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	79.50	0.00e+00	1852.00
IUUC-Kpa-049281	Komagataella pastoris	40.53	8.00e-80	291.00
IUUC-Lch-050330	Latimeria chalumnae	45.81	0.00e+00	941.00
IUUC-Lpe-051214	Leersia perrieri	45.28	6.00e-83	301.00
IUUC-Lma-053263	Leptosphaeria maculans	44.76	4.00e-87	316.00
IUUC-Laf-053386	Loxodonta africana	72.21	0.00e+00	1672.00
IUUC-Mcc-055530	Macaca mulatta	98.40	0.00e+00	2275.00
IUUC-Meu-056442	Macropus eugenii	67.63	0.00e+00	958.00
IUUC-Mor-057095	Magnaporthe oryzae	40.10	2.00e-78	287.00
IUUC-Mpo-057389	Magnaporthe poae	43.02	4.00e-75	276.00
IUUC-Mtr-058463	Medicago truncatula	46.56	1.00e-85	310.00
IUUC-Mla-059143	Melampsora laricipopulina	44.28	4.00e-80	292.00
IUUC-Mmr-060637	Microcebus murinus	87.58	0.00e+00	2073.00
IUUC-Mdo-062198	Monodelphis domestica	66.58	0.00e+00	1054.00
IUUC-Mmu-063346	Mus musculus	74.49	0.00e+00	1721.00
IUUC-Mac-064630	Musa acuminata	44.79	7.00e-83	301.00
IUUC-Mpu-065884	Mustela putorius furo	77.96	0.00e+00	1805.00
IUUC-Mlu-068117	Myotis lucifugus	76.90	0.00e+00	1778.00
IUUC-Nfi-068404	Neosartorya fischeri	45.45	9.00e-83	301.00
IUUC-Ncr-068672	Neurospora crassa	43.39	4.00e-76	279.00
IUUC-Nle-069868	Nomascus leucogenys	98.69	0.00e+00	787.00
IUUC-Opr-071074	Ochotona princeps	71.33	0.00e+00	1125.00
IUUC-Ont-072246	Oreochromis niloticus	45.63	0.00e+00	945.00
IUUC-Oan-072911	Ornithorhynchus anatinus	68.24	7.00e-107	381.00
IUUC-Ocu-074627	Oryctolagus cuniculus	77.75	0.00e+00	1831.00
IUUC-Oba-075489	Oryza barthii	44.69	1.00e-81	297.00
IUUC-Obr-076150	Oryza brachyantha	44.83	2.00e-82	300.00
IUUC-Ogl-077437	Oryza glaberrima	44.69	9.00e-82	298.00
IUUC-Ogu-078370	Oryza glumaepatula	45.00	1.00e-82	300.00
IUUC-Oin-079210	Oryza indica	45.00	1.00e-82	300.00
IUUC-Olo-080971	Oryza longistaminata	45.99	4.00e-72	265.00
IUUC-Oni-082031	Oryza nivara	45.00	2.00e-82	300.00
IUUC-Opu-083471	Oryza punctata	44.27	6.00e-82	298.00
IUUC-Oru-084755	Oryza rufipogon	45.00	1.00e-82	300.00
IUUC-Osa-085447	Oryza sativa	45.00	2.00e-82	300.00
IUUC-Oga-089155	Otolemur garnettii	85.27	0.00e+00	1984.00
IUUC-Oar-089620	Ovis aries	82.28	0.00e+00	1488.00
IUUC-Ptr-090812	Pan troglodytes	99.43	0.00e+00	1396.00
IUUC-Pan-092340	Papio anubis	98.61	0.00e+00	2284.00
IUUC-Pma-094386	Petromyzon marinus	53.78	0.00e+00	808.00
IUUC-Pno-095131	Phaeosphaeria nodorum	47.70	4.00e-73	268.00
IUUC-Ppa-095550	Physcomitrella patens	48.79	9.00e-87	314.00
IUUC-Pfo-096110	Poecilia formosa	52.60	0.00e+00	712.00
IUUC-Pab-098422	Pongo abelii	97.56	0.00e+00	2244.00
IUUC-Pop-099174	Populus trichocarpa	44.69	6.00e-80	291.00
IUUC-Pca-100833	Procavia capensis	71.12	0.00e+00	1550.00
IUUC-Ppe-101644	Prunus persica	43.23	3.00e-86	312.00
IUUC-Pva-102410	Pteropus vampyrus	74.20	0.00e+00	1671.00
IUUC-Ptt-103841	Puccinia triticina	39.03	4.00e-76	279.00
IUUC-Pte-104383	Pyrenophora teres	43.85	5.00e-82	299.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	44.12	3.00e-82	299.00
IUUC-Rno-105131	Rattus norvegicus	74.11	0.00e+00	1692.00
IUUC-Sce-106274	Saccharomyces cerevisiae	38.54	4.00e-78	286.00
IUUC-Sha-106661	Sarcophilus harrisii	55.53	0.00e+00	798.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	42.55	5.00e-85	308.00
IUUC-Spo-108300	Schizosaccharomyces pombe	45.36	2.00e-83	303.00
IUUC-Smo-109615	Selaginella moellendorffii	43.69	8.00e-86	311.00
IUUC-Sit-110160	Setaria italica	44.65	1.00e-77	284.00
IUUC-Sly-111164	Solanum lycopersicum	42.11	9.00e-79	288.00
IUUC-Stu-112685	Solanum tuberosum	41.96	7.00e-67	248.00
IUUC-Sar-113692	Sorex araneus	66.61	0.00e+00	766.00
IUUC-Sbi-114301	Sorghum bicolor	45.03	1.00e-77	284.00
IUUC-Sre-115013	Sporisorium reilianum	43.77	6.00e-84	305.00
IUUC-Ssc-115724	Sus scrofa	76.08	0.00e+00	1663.00
IUUC-Tgu-116605	Taeniopygia guttata	47.47	0.00e+00	669.00
IUUC-Tru-117614	Takifugu rubripes	55.92	0.00e+00	851.00
IUUC-Tsy-118807	Tarsius syrichta	80.19	0.00e+00	1067.00
IUUC-Tni-119809	Tetraodon nigroviridis	54.46	0.00e+00	774.00
IUUC-Tca-121312	Theobroma cacao	45.99	8.00e-83	301.00
IUUC-Tre-121930	Trichoderma reesei	40.45	7.00e-77	281.00
IUUC-Tvi-122373	Trichoderma virens	40.94	5.00e-77	282.00
IUUC-Tae-123064	Triticum aestivum	42.39	1.00e-77	283.00
IUUC-Tme-127027	Tuber melanosporum	41.53	9.00e-70	257.00
IUUC-Tbe-127675	Tupaia belangeri	68.24	1.00e-128	454.00
IUUC-Ttr-128411	Tursiops truncatus	75.85	0.00e+00	1759.00
IUUC-Uma-129408	Ustilago maydis	47.08	2.00e-76	280.00
IUUC-Vda-129994	Verticillium dahliae	39.07	3.00e-71	263.00
IUUC-Vpa-130525	Vicugna pacos	80.85	3.00e-61	230.00
IUUC-Vvi-131038	Vitis vinifera	44.69	4.00e-84	305.00
IUUC-Xtr-132618	Xenopus tropicalis	48.32	0.00e+00	1038.00
IUUC-Xma-133730	Xiphophorus maculatus	49.43	0.00e+00	698.00
IUUC-Yli-134680	Yarrowia lipolytica	42.31	2.00e-83	303.00
IUUC-Zma-135110	Zea mays	44.83	2.00e-78	286.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence