iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000013940.1	ENSAMET00000015359.1	ENSAMEP00000014751.1
ENSAMEG00000013940.1	ENSAMET00000015370.1	ENSAMEP00000014762.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	96.05	0.00e+00	1933.00	IUUC-Hsa-046884

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MAENVVEPGP PSAKRPKLSS PALSASASDG TDFGSLFDLE HDLPDELINS TELGLTNGGD 60
ISQLQTSLGI VQDAASKHKQ LSELLRSGSS PNLNMGVGGP GQGMASQPQQ NSPGLGLINS 120

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Nucleotide Sequence
(Fasta)

ATGGCCGAGA ATGTGGTGGA ACCGGGGCCG CCTTCAGCCA AGCGGCCTAA ACTCTCATCT 60
CCGGCCCTCT CGGCTTCGGC CAGCGATGGC ACAGGTTAGT CCGGGGAGCC CTGGCCTTCC 120

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Sequence Source

Ensembl

Keyword

KW-0012--Acyltransferase
KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR031162--CBP_P300_HAT
IPR013178--Histone_AcTrfase_Rtt109/CBP
IPR003101--KIX_dom
IPR009110--Nuc_rcpt_coact
IPR014744--Nuc_rcpt_coact_CREBbp
IPR010303--RING_CBP-p300
IPR000197--Znf_TAZ
IPR000433--Znf_ZZ

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51727--CBP_P300_HAT
PS50952--KIX
PS50134--ZF_TAZ
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00439--Bromodomain
PF09030--Creb_binding
PF06001--DUF902
PF08214--HAT_KAT11
PF02172--KIX
PF02135--zf-TAZ
PF00569--ZZ

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM01250--KAT11
SM00551--ZnF_TAZ
SM00291--ZnF_ZZ

Gene Ontology

GO:0005829--C:cytosol
GO:0000123--C:histone acetyltransferase complex
GO:0005667--C:transcription factor complex
GO:0031490--F:chromatin DNA binding
GO:0003684--F:damaged DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0004468--F:lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0097157--F:pre-mRNA intronic binding
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0001228--F:transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0009887--P:animal organ morphogenesis
GO:0030183--P:B cell differentiation
GO:0034644--P:cellular response to UV
GO:0007623--P:circadian rhythm
GO:0045444--P:fat cell differentiation
GO:0007507--P:heart development
GO:0043969--P:histone H2B acetylation
GO:0043967--P:histone H4 acetylation
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0030324--P:lung development
GO:0010742--P:macrophage derived foam cell differentiation
GO:0035855--P:megakaryocyte development
GO:0018076--P:N-terminal peptidyl-lysine acetylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030220--P:platelet formation
GO:0043923--P:positive regulation by host of viral transcription
GO:0032092--P:positive regulation of protein binding
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0006990--P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
GO:0050821--P:protein stabilization
GO:0060765--P:regulation of androgen receptor signaling pathway
GO:0090043--P:regulation of tubulin deacetylation
GO:0043627--P:response to estrogen
GO:0001666--P:response to hypoxia
GO:0007519--P:skeletal muscle tissue development
GO:0001756--P:somitogenesis

KEGG

aml:100468694

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005040	Anolis carolinensis	79.95	0.00e+00	1837.00
IUUC-Ame-011395	Astyanax mexicanus	85.31	0.00e+00	1438.00
IUUC-Bta-012649	Bos taurus	93.23	0.00e+00	2027.00
IUUC-Cel-018691	Caenorhabditis elegans	49.23	0.00e+00	845.00
IUUC-Cja-019649	Callithrix jacchus	93.43	0.00e+00	2109.00
IUUC-Cfa-020764	Canis familiaris	98.38	0.00e+00	1805.00
IUUC-Cpo-022345	Cavia porcellus	90.35	0.00e+00	3340.00
IUUC-Cre-022852	Chlamydomonas reinhardtii	34.84	5.00e-65	243.00
IUUC-Csa-023866	Chlorocebus sabaeus	95.25	0.00e+00	2053.00
IUUC-Cho-024951	Choloepus hoffmanni	98.32	0.00e+00	1245.00
IUUC-Csv-026122	Ciona savignyi	65.28	0.00e+00	679.00
IUUC-Dre-028500	Danio rerio	78.51	0.00e+00	1464.00
IUUC-Ete-032979	Echinops telfairi	89.87	0.00e+00	1754.00
IUUC-Eca-034048	Equus caballus	96.78	0.00e+00	1909.00
IUUC-Fca-035891	Felis catus	95.81	0.00e+00	2057.00
IUUC-Fal-037585	Ficedula albicollis	83.85	0.00e+00	1884.00
IUUC-Gmo-039348	Gadus morhua	87.35	0.00e+00	1443.00
IUUC-Gga-040916	Gallus gallus	83.38	0.00e+00	1904.00
IUUC-Gac-041642	Gasterosteus aculeatus	87.58	0.00e+00	1417.00
IUUC-Ggo-045189	Gorilla gorilla	94.98	0.00e+00	2060.00
IUUC-Hsa-046884	Homo sapiens	94.91	0.00e+00	2060.00
IUUC-Itr-048564	Ictidomys tridecemlineatus	96.52	0.00e+00	1851.00
IUUC-Laf-054423	Loxodonta africana	94.46	0.00e+00	2167.00
IUUC-Mcc-054847	Macaca mulatta	95.11	0.00e+00	2059.00
IUUC-Meu-056217	Macropus eugenii	83.33	0.00e+00	1931.00
IUUC-Mga-059250	Meleagris gallopavo	79.72	0.00e+00	1925.00
IUUC-Mmr-061496	Microcebus murinus	94.92	0.00e+00	2051.00
IUUC-Mdo-062478	Monodelphis domestica	85.65	0.00e+00	1931.00
IUUC-Mmu-063456	Mus musculus	94.77	0.00e+00	1895.00
IUUC-Mac-064767	Musa acuminata	40.75	1.00e-75	278.00
IUUC-Mpu-065963	Mustela putorius furo	94.99	0.00e+00	2024.00
IUUC-Mlu-067185	Myotis lucifugus	95.74	0.00e+00	1895.00
IUUC-Ncr-068795	Neurospora crassa	37.97	1.00e-13	71.20
IUUC-Nle-069907	Nomascus leucogenys	95.92	0.00e+00	1867.00
IUUC-Opr-070324	Ochotona princeps	89.41	0.00e+00	1193.00
IUUC-Ont-072211	Oreochromis niloticus	78.85	0.00e+00	1447.00
IUUC-Oan-073723	Ornithorhynchus anatinus	87.97	0.00e+00	1834.00
IUUC-Ocu-074707	Oryctolagus cuniculus	95.25	0.00e+00	1865.00
IUUC-Oba-075590	Oryza barthii	33.38	3.00e-102	367.00
IUUC-Ogu-078580	Oryza glumaepatula	33.24	2.00e-102	368.00
IUUC-Ome-081615	Oryza meridionalis	33.38	3.00e-102	367.00
IUUC-Oni-082636	Oryza nivara	33.38	2.00e-102	367.00
IUUC-Opu-084073	Oryza punctata	32.83	8.00e-99	356.00
IUUC-Oru-084994	Oryza rufipogon	33.38	2.00e-102	367.00
IUUC-Osa-085860	Oryza sativa	41.94	2.00e-62	234.00
IUUC-Olu-087701	Ostreococcus lucimarinus	35.44	2.00e-62	234.00
IUUC-Oga-088700	Otolemur garnettii	94.58	0.00e+00	3447.00
IUUC-Oar-089787	Ovis aries	90.53	0.00e+00	2007.00
IUUC-Ptr-091620	Pan troglodytes	94.15	0.00e+00	2061.00
IUUC-Pan-092166	Papio anubis	94.29	0.00e+00	2075.00
IUUC-Psi-093992	Pelodiscus sinensis	83.29	0.00e+00	1977.00
IUUC-Ppa-095569	Physcomitrella patens	38.23	5.00e-71	263.00
IUUC-Pfo-097342	Poecilia formosa	84.89	0.00e+00	1380.00
IUUC-Pab-098235	Pongo abelii	94.43	0.00e+00	2055.00
IUUC-Pop-098947	Populus trichocarpa	40.00	6.00e-74	273.00
IUUC-Pca-100780	Procavia capensis	89.21	0.00e+00	1460.00
IUUC-Pva-103071	Pteropus vampyrus	94.79	0.00e+00	2175.00
IUUC-Sha-106736	Sarcophilus harrisii	91.94	0.00e+00	1679.00
IUUC-Smo-109420	Selaginella moellendorffii	38.27	1.00e-71	265.00
IUUC-Sar-113162	Sorex araneus	92.32	0.00e+00	835.00
IUUC-Ssc-116077	Sus scrofa	94.59	0.00e+00	2085.00
IUUC-Tgu-116872	Taeniopygia guttata	84.07	0.00e+00	1902.00
IUUC-Tsy-119451	Tarsius syrichta	95.37	0.00e+00	1330.00
IUUC-Tca-121835	Theobroma cacao	39.00	2.00e-73	271.00
IUUC-Tae-124383	Triticum aestivum	38.48	1.00e-68	255.00
IUUC-Tbe-127772	Tupaia belangeri	85.88	0.00e+00	1288.00
IUUC-Vpa-130766	Vicugna pacos	97.11	0.00e+00	1369.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence