iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054479

UUCD1 version

UUC-LoA-00051

Ensembl Protein ID

ENSLAFP00000001374.2

UniProt Accession

G3SNY9; G3SNY9_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TRIM72

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000001647.2	ENSLAFT00000001647.2	ENSLAFP00000001374.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.60e-06	28.9	14	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cl+ f+  p++  CgH f++ Cl ++      + ++ +CP C+
   Q: 14   CPLCLQLFDA-PVTAECGHSFCRACLGRV-AGEPAADGTVLCPCCQ 57
           ********99.999***************.5555799999*****7 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MSAAPGLLHQ ELSCPLCLQL FDAPVTAECG HSFCRACLGR VAGEPAADGT VLCPCCQAPT 60
RPQALNTNLQ LARLVEGLGQ VPQGHCEEHL DPLSIYCEQD RALVCGVCAS LGSHRGHRLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGCTG CGCCCGGCCT CCTACACCAG GAGCTGTCCT GCCCGCTGTG CCTGCAGCTG 60
TTCGATGCGC CCGTGACGGC CGAATGCGGC CACAGCTTCT GCCGCGCCTG CCTGGGTCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0030659--C:cytoplasmic vesicle membrane
GO:0042383--C:sarcolemma
GO:0001786--F:phosphatidylserine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007517--P:muscle organ development
GO:0003012--P:muscle system process
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0043569--P:negative regulation of insulin-like growth factor receptor signaling pathway
GO:0010832--P:negative regulation of myotube differentiation
GO:0001778--P:plasma membrane repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051260--P:protein homooligomerization

KEGG

lav:100664587

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002377	Ailuropoda melanoleuca	76.14	0.00e+00	660.00
IUUC-Aca-004755	Anolis carolinensis	63.11	7.00e-173	600.00
IUUC-Bta-013476	Bos taurus	79.50	0.00e+00	722.00
IUUC-Cel-018370	Caenorhabditis elegans	37.63	4.00e-08	52.00
IUUC-Cja-018969	Callithrix jacchus	81.61	0.00e+00	725.00
IUUC-Cfa-020155	Canis familiaris	91.40	0.00e+00	854.00
IUUC-Cpo-021646	Cavia porcellus	88.03	0.00e+00	817.00
IUUC-Csa-023855	Chlorocebus sabaeus	91.89	1.00e-171	595.00
IUUC-Dno-029142	Dasypus novemcinctus	89.94	0.00e+00	770.00
IUUC-Dor-030394	Dipodomys ordii	66.67	9.00e-85	307.00
IUUC-Ete-032801	Echinops telfairi	86.05	1.00e-64	239.00
IUUC-Eca-034378	Equus caballus	91.61	0.00e+00	840.00
IUUC-Eeu-034526	Erinaceus europaeus	84.84	0.00e+00	751.00
IUUC-Fca-036440	Felis catus	92.03	0.00e+00	867.00
IUUC-Ggo-045086	Gorilla gorilla	94.83	0.00e+00	681.00
IUUC-Hsa-046533	Homo sapiens	93.08	0.00e+00	840.00
IUUC-Itr-048959	Ictidomys tridecemlineatus	91.82	0.00e+00	863.00
IUUC-Mcc-055814	Macaca mulatta	91.23	0.00e+00	812.00
IUUC-Meu-056767	Macropus eugenii	73.40	0.00e+00	689.00
IUUC-Mmr-061616	Microcebus murinus	91.82	0.00e+00	864.00
IUUC-Mdo-062252	Monodelphis domestica	76.20	0.00e+00	721.00
IUUC-Mmu-063094	Mus musculus	89.10	0.00e+00	820.00
IUUC-Mpu-065885	Mustela putorius furo	77.78	0.00e+00	669.00
IUUC-Mlu-068150	Myotis lucifugus	92.86	4.00e-65	241.00
IUUC-Nle-069476	Nomascus leucogenys	93.31	0.00e+00	839.00
IUUC-Opr-070871	Ochotona princeps	90.60	1.00e-140	493.00
IUUC-Oan-072738	Ornithorhynchus anatinus	76.26	0.00e+00	721.00
IUUC-Ocu-074132	Oryctolagus cuniculus	93.94	0.00e+00	660.00
IUUC-Olu-087666	Ostreococcus lucimarinus	37.84	3.00e-10	59.70
IUUC-Oga-088268	Otolemur garnettii	63.60	1.00e-147	516.00
IUUC-Oar-089555	Ovis aries	68.96	1.00e-163	568.00
IUUC-Ptr-090792	Pan troglodytes	93.08	0.00e+00	840.00
IUUC-Pan-092897	Papio anubis	92.87	0.00e+00	843.00
IUUC-Pab-098716	Pongo abelii	93.08	0.00e+00	839.00
IUUC-Pca-100618	Procavia capensis	85.74	0.00e+00	787.00
IUUC-Pva-102430	Pteropus vampyrus	81.55	0.00e+00	741.00
IUUC-Rno-105665	Rattus norvegicus	88.89	0.00e+00	840.00
IUUC-Sha-106854	Sarcophilus harrisii	65.21	4.00e-174	604.00
IUUC-Sar-113028	Sorex araneus	89.18	3.00e-140	491.00
IUUC-Ssc-116124	Sus scrofa	91.75	0.00e+00	828.00
IUUC-Tbe-127273	Tupaia belangeri	89.41	1.00e-124	439.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence