iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062097

Ensembl Protein ID

ENSMODP00000026122.3

UniProt Accession

H9H7Q5; H9H7Q5_MONDO

Protein Name

Uncharacterized protein

Gene Name

PHF8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000020891.3	ENSMODT00000026587.3	ENSMODP00000026122.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.00e-08	35.4	42	90

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C+ +++ ++ ++eC+ C++wfH  C++ + ee+  + + + Cp+C+
   Q: 42   VYC-LCRLPYDVTRFMIECDLCQDWFHGSCVGVE-EEKAVDIDLYHCPNCE 90
           69*.******************************.999999999******6 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSAAPGDPPA SGGHVCPPRG ARAQERAEAR AQARAKMASP PVYCLCRLPY DVTRFMIECD 60
LCQDWFHGSC VGVEEEKAVD IDLYHCPNCE VLHGPSVMKR RRGAPKVQEL LASKEGGKTV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGCGG CGCCCGGCGA TCCGCCGGCC TCTGGCGGTC ACGTTTGCCC CCCGCGAGGG 60
GCACGGGCCC AGGAACGGGC CGAAGCGCGA GCCCAGGCGC GGGCCAAGAT GGCCTCCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003347--JmjC_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF02373--JmjC
PF00628--PHD

SMART

SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0031965--C:nuclear membrane
GO:0005730--C:nucleolus
GO:0003682--F:chromatin binding
GO:0071558--F:histone demethylase activity (H3-K27 specific)
GO:0051864--F:histone demethylase activity (H3-K36 specific)
GO:0032454--F:histone demethylase activity (H3-K9 specific)
GO:0035575--F:histone demethylase activity (H4-K20 specific)
GO:0005506--F:iron ion binding
GO:0008270--F:zinc ion binding
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0061188--P:negative regulation of chromatin silencing at rDNA
GO:0045943--P:positive regulation of transcription from RNA polymerase I promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002427	Ailuropoda melanoleuca	70.22	0.00e+00	1153.00
IUUC-Atr-002986	Amborella trichopoda	43.75	2.00e-10	59.30
IUUC-Aca-004346	Anolis carolinensis	69.97	0.00e+00	1152.00
IUUC-Aly-005443	Arabidopsis lyrata	34.33	1.00e-10	59.70
IUUC-Ath-006906	Arabidopsis thaliana	34.33	9.00e-10	57.00
IUUC-Acl-008303	Aspergillus clavatus	31.98	7.00e-67	249.00
IUUC-Afl-008579	Aspergillus flavus	28.85	4.00e-29	123.00
IUUC-Ani-009279	Aspergillus nidulans	32.32	5.00e-65	243.00
IUUC-Ang-009645	Aspergillus niger	30.91	1.00e-62	234.00
IUUC-Aor-010233	Aspergillus oryzae	31.98	2.00e-66	247.00
IUUC-Ate-010345	Aspergillus terreus	32.19	4.00e-68	253.00
IUUC-Ame-010945	Astyanax mexicanus	60.24	0.00e+00	1035.00
IUUC-Bdi-014153	Brachypodium distachyon	39.62	2.00e-10	58.50
IUUC-Cfa-021156	Canis familiaris	70.02	0.00e+00	1261.00
IUUC-Cpo-022284	Cavia porcellus	70.66	0.00e+00	1280.00
IUUC-Cre-022934	Chlamydomonas reinhardtii	42.19	4.00e-10	57.80
IUUC-Csa-023515	Chlorocebus sabaeus	71.30	0.00e+00	1298.00
IUUC-Cme-027118	Cyanidioschyzon merolae	31.45	6.00e-51	195.00
IUUC-Dre-028423	Danio rerio	60.31	0.00e+00	1019.00
IUUC-Dno-029446	Dasypus novemcinctus	72.99	0.00e+00	961.00
IUUC-Dse-031402	Dothistroma septosporum	32.37	7.00e-64	239.00
IUUC-Ete-032380	Echinops telfairi	79.93	0.00e+00	927.00
IUUC-Eca-034302	Equus caballus	70.35	0.00e+00	1277.00
IUUC-Fca-035578	Felis catus	70.35	0.00e+00	1289.00
IUUC-Fal-037017	Ficedula albicollis	63.23	0.00e+00	644.00
IUUC-Gmo-038789	Gadus morhua	57.71	0.00e+00	1025.00
IUUC-Gga-040290	Gallus gallus	63.68	0.00e+00	646.00
IUUC-Gac-041666	Gasterosteus aculeatus	79.22	0.00e+00	810.00
IUUC-Gma-042998	Glycine max	41.67	6.00e-10	57.40
IUUC-Ggo-044712	Gorilla gorilla	71.00	0.00e+00	1296.00
IUUC-Hsa-045724	Homo sapiens	71.23	0.00e+00	1302.00
IUUC-Kpa-049384	Komagataella pastoris	34.29	2.00e-59	223.00
IUUC-Lch-049793	Latimeria chalumnae	83.44	0.00e+00	866.00
IUUC-Lpe-051400	Leersia perrieri	42.59	4.00e-11	61.60
IUUC-Loc-051927	Lepisosteus oculatus	64.37	0.00e+00	646.00
IUUC-Lma-053190	Leptosphaeria maculans	35.57	7.00e-66	246.00
IUUC-Laf-053656	Loxodonta africana	71.68	0.00e+00	1217.00
IUUC-Mcc-055658	Macaca mulatta	71.30	0.00e+00	1298.00
IUUC-Mtr-057679	Medicago truncatula	37.68	2.00e-11	62.00
IUUC-Mla-058890	Melampsora laricipopulina	49.28	2.00e-76	278.00
IUUC-Mvi-060481	Microbotryum violaceum	39.73	3.00e-77	283.00
IUUC-Mmr-060993	Microcebus murinus	71.12	0.00e+00	1272.00
IUUC-Mmu-063909	Mus musculus	70.89	0.00e+00	1288.00
IUUC-Mpu-066429	Mustela putorius furo	70.32	0.00e+00	1282.00
IUUC-Mlu-067746	Myotis lucifugus	69.24	0.00e+00	1266.00
IUUC-Nfi-068537	Neosartorya fischeri	31.78	4.00e-66	247.00
IUUC-Nle-070143	Nomascus leucogenys	71.02	0.00e+00	1316.00
IUUC-Ont-072257	Oreochromis niloticus	60.11	0.00e+00	983.00
IUUC-Oan-073654	Ornithorhynchus anatinus	78.48	0.00e+00	897.00
IUUC-Ocu-074417	Oryctolagus cuniculus	70.62	0.00e+00	1246.00
IUUC-Oba-075975	Oryza barthii	32.88	1.00e-10	59.70
IUUC-Ogl-077326	Oryza glaberrima	32.88	1.00e-10	59.70
IUUC-Ogu-078224	Oryza glumaepatula	32.88	8.00e-11	60.10
IUUC-Oin-079199	Oryza indica	32.88	8.00e-11	60.10
IUUC-Ome-081623	Oryza meridionalis	43.75	2.00e-10	58.90
IUUC-Oni-082302	Oryza nivara	32.88	8.00e-11	60.10
IUUC-Opu-083591	Oryza punctata	43.75	1.00e-10	59.30
IUUC-Oru-085087	Oryza rufipogon	32.88	8.00e-11	60.10
IUUC-Osa-085343	Oryza sativa	32.88	1.00e-10	59.70
IUUC-Ola-087502	Oryzias latipes	56.75	0.00e+00	1012.00
IUUC-Olu-087802	Ostreococcus lucimarinus	47.06	2.00e-13	68.60
IUUC-Oga-088662	Otolemur garnettii	69.85	0.00e+00	1092.00
IUUC-Oar-090332	Ovis aries	69.83	0.00e+00	1268.00
IUUC-Ptr-091646	Pan troglodytes	71.36	0.00e+00	1105.00
IUUC-Pan-092122	Papio anubis	71.30	0.00e+00	1297.00
IUUC-Pma-094621	Petromyzon marinus	67.41	0.00e+00	643.00
IUUC-Pno-094984	Phaeosphaeria nodorum	34.74	1.00e-64	242.00
IUUC-Pfo-096107	Poecilia formosa	79.83	0.00e+00	817.00
IUUC-Pab-097635	Pongo abelii	62.72	0.00e+00	1068.00
IUUC-Pop-099324	Populus trichocarpa	41.67	7.00e-11	60.50
IUUC-Pca-100779	Procavia capensis	63.14	0.00e+00	663.00
IUUC-Pva-102839	Pteropus vampyrus	60.81	0.00e+00	1041.00
IUUC-Ptt-103859	Puccinia triticina	38.81	3.00e-78	286.00
IUUC-Pte-104241	Pyrenophora teres	33.25	1.00e-63	238.00
IUUC-Pyt-104741	Pyrenophora triticirepentis	33.83	2.00e-62	234.00
IUUC-Rno-105933	Rattus norvegicus	70.40	0.00e+00	1288.00
IUUC-Sja-107763	Schizosaccharomyces japonicus	35.06	4.00e-48	186.00
IUUC-Sit-110474	Setaria italica	45.28	2.00e-11	62.40
IUUC-Sly-110932	Solanum lycopersicum	41.67	5.00e-10	57.40
IUUC-Stu-112357	Solanum tuberosum	41.67	6.00e-10	57.40
IUUC-Sbi-114098	Sorghum bicolor	45.28	2.00e-11	62.40
IUUC-Ssc-115645	Sus scrofa	70.71	0.00e+00	1241.00
IUUC-Tgu-117091	Taeniopygia guttata	63.23	0.00e+00	644.00
IUUC-Tru-118403	Takifugu rubripes	77.13	0.00e+00	803.00
IUUC-Tsy-119214	Tarsius syrichta	65.10	0.00e+00	955.00
IUUC-Tni-119736	Tetraodon nigroviridis	80.04	0.00e+00	804.00
IUUC-Tme-127054	Tuber melanosporum	31.28	3.00e-56	214.00
IUUC-Tbe-128138	Tupaia belangeri	69.42	0.00e+00	1102.00
IUUC-Ttr-128194	Tursiops truncatus	61.86	2.00e-180	626.00
IUUC-Vpa-130595	Vicugna pacos	61.24	0.00e+00	741.00
IUUC-Xtr-132307	Xenopus tropicalis	66.19	0.00e+00	1131.00
IUUC-Xma-134323	Xiphophorus maculatus	80.69	0.00e+00	823.00
IUUC-Yli-134626	Yarrowia lipolytica	35.98	6.00e-60	224.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence