iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041741

UUCD1 version

UUC-GaA-00903

Ensembl Protein ID

ENSGACP00000022871.1

UniProt Accession

G3PZ31; G3PZ31_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000017317.1	ENSGACT00000022914.1	ENSGACP00000022871.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.20e-95	319.1	721	1045

Active Site

Position(s)	Description	Evidence
1014	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlld 89
            dlkk l+v f gEe++d+gGvt+ef+ ll+kel +p +g+f++ ++++  ++ ++        + ++F+++G+++g+a++++ ++d
   Q: 721  VDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELMDPVYGMFTHYKDSNLLWFSDKCFV-----EQNWFHLIGIICGLAIYNSTVVD 802
           589****************************************9999999999888665.....579******************** PP
   S: 90   lplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvkl 176
           l+++ ++yk+ll+++ +led++e+ p+ ++sl+++++++  d+ee+ + l+f ++ e++g t+++eL+pgGe i+V ++N++e+v++
   Q: 803  LHFPLVLYKKLLNVSPTLEDFKELSPTEARSLQQLLDYDGCDVEEM-FLLNFAITRENYGMTEVKELIPGGEGISVDKNNRKEFVEA 888
           **************************************999***99.9*************************************** PP
   S: 177  vveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerka 263
           ++ y + +++ eq+ af++Gf +v+  e+l lF+++el  ++ G++++++e+++k++ ykg+yt+++p+++ Fwev++ef  e++k+
   Q: 889  YLRYVFSDSVSEQYSAFSSGFLKVCGGEILPLFQPSELMAMVVGNNNYNWEEMEKNAVYKGEYTATHPTVRLFWEVFHEFPLEKKKQ 975
           *************************************************************************************** PP
   S: 264  fLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           fL F+Tgs+r+P+ G+++l+   +vi+   a+++ lP ++TC+n+L++P+Y++keil+++L+ A+e+ +gF+l
   Q: 976  FLLFLTGSDRIPIHGMESLR---IVIQStTAEEHYLPVAHTCYNLLDMPRYQTKEILRRRLTRAVEQYEGFSL 1045
           ********************...8888867777**************************************97 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MLCWGNAKDG QLGIGIDRTA MFEPRNCHVF SGRGLKEVAC GGQHSTFLLH DGSVYTCGSN 60
SCGQLGHSKP GTSPELVDAL DAQIITMVSS GRSHSVAVNE QGQVFAWGAG EEGQLGLGIA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTTTGTT GGGGGAATGC AAAAGATGGA CAGCTGGGTA TCGGTATTGA CAGGACCGCC 60
ATGTTTGAGC CCAGAAACTG TCACGTGTTC AGTGGCAGGG GCCTGAAAGA AGTAGCTTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001673	Ailuropoda melanoleuca	65.28	0.00e+00	1344.00
IUUC-Apl-003535	Anas platyrhynchos	65.94	0.00e+00	1362.00
IUUC-Aca-005223	Anolis carolinensis	64.52	0.00e+00	1334.00
IUUC-Ame-010816	Astyanax mexicanus	78.09	0.00e+00	1373.00
IUUC-Bta-013373	Bos taurus	65.28	0.00e+00	1351.00
IUUC-Bdi-014791	Brachypodium distachyon	37.58	4.00e-53	202.00
IUUC-Cja-019609	Callithrix jacchus	65.37	0.00e+00	1343.00
IUUC-Cfa-021071	Canis familiaris	65.09	0.00e+00	1340.00
IUUC-Cpo-021548	Cavia porcellus	65.09	0.00e+00	1340.00
IUUC-Csa-023987	Chlorocebus sabaeus	65.37	0.00e+00	1345.00
IUUC-Cho-024325	Choloepus hoffmanni	71.90	0.00e+00	870.00
IUUC-Dre-027472	Danio rerio	79.14	0.00e+00	1674.00
IUUC-Dno-029241	Dasypus novemcinctus	64.74	0.00e+00	1326.00
IUUC-Dor-030672	Dipodomys ordii	54.31	0.00e+00	627.00
IUUC-Ete-032642	Echinops telfairi	63.76	0.00e+00	1263.00
IUUC-Eca-033646	Equus caballus	64.99	0.00e+00	1337.00
IUUC-Eeu-035098	Erinaceus europaeus	62.10	0.00e+00	822.00
IUUC-Fal-036952	Ficedula albicollis	66.03	0.00e+00	1362.00
IUUC-Gmo-039297	Gadus morhua	78.86	0.00e+00	1644.00
IUUC-Gga-040591	Gallus gallus	65.65	0.00e+00	1356.00
IUUC-Ggo-044769	Gorilla gorilla	65.21	0.00e+00	1339.00
IUUC-Hsa-046066	Homo sapiens	65.18	0.00e+00	1341.00
IUUC-Itr-048311	Ictidomys tridecemlineatus	65.40	0.00e+00	1346.00
IUUC-Lch-050301	Latimeria chalumnae	66.95	0.00e+00	1439.00
IUUC-Lpe-051165	Leersia perrieri	33.70	3.00e-48	185.00
IUUC-Loc-052803	Lepisosteus oculatus	75.97	0.00e+00	1648.00
IUUC-Laf-053364	Loxodonta africana	65.75	0.00e+00	1352.00
IUUC-Mcc-054930	Macaca mulatta	65.37	0.00e+00	1345.00
IUUC-Meu-056274	Macropus eugenii	52.56	1.00e-151	531.00
IUUC-Mga-059563	Meleagris gallopavo	65.94	0.00e+00	1363.00
IUUC-Mmr-060792	Microcebus murinus	64.42	0.00e+00	1319.00
IUUC-Mdo-062195	Monodelphis domestica	65.81	0.00e+00	1356.00
IUUC-Mmu-063855	Mus musculus	64.33	0.00e+00	1338.00
IUUC-Mpu-066308	Mustela putorius furo	65.28	0.00e+00	1345.00
IUUC-Mlu-066927	Myotis lucifugus	65.18	0.00e+00	1347.00
IUUC-Nle-070090	Nomascus leucogenys	65.28	0.00e+00	1344.00
IUUC-Opr-070891	Ochotona princeps	58.06	0.00e+00	1140.00
IUUC-Ont-072201	Oreochromis niloticus	87.57	0.00e+00	1870.00
IUUC-Ocu-074770	Oryctolagus cuniculus	64.99	0.00e+00	1344.00
IUUC-Oba-075262	Oryza barthii	35.69	1.00e-47	184.00
IUUC-Obr-076115	Oryza brachyantha	33.04	1.00e-45	177.00
IUUC-Ogl-077586	Oryza glaberrima	35.69	1.00e-47	184.00
IUUC-Ogu-078796	Oryza glumaepatula	35.69	1.00e-47	184.00
IUUC-Oin-079298	Oryza indica	35.69	8.00e-48	184.00
IUUC-Olo-080768	Oryza longistaminata	36.12	5.00e-53	201.00
IUUC-Ome-081908	Oryza meridionalis	35.33	2.00e-46	179.00
IUUC-Oni-082049	Oryza nivara	35.69	1.00e-47	184.00
IUUC-Opu-083608	Oryza punctata	36.20	1.00e-47	184.00
IUUC-Oru-084712	Oryza rufipogon	35.69	1.00e-47	184.00
IUUC-Osa-086078	Oryza sativa	35.69	1.00e-47	184.00
IUUC-Ola-086550	Oryzias latipes	84.64	0.00e+00	1826.00
IUUC-Olu-087836	Ostreococcus lucimarinus	33.63	2.00e-42	166.00
IUUC-Oga-088831	Otolemur garnettii	64.80	0.00e+00	1332.00
IUUC-Oar-090449	Ovis aries	65.28	0.00e+00	1347.00
IUUC-Pan-092135	Papio anubis	65.21	0.00e+00	1344.00
IUUC-Psi-093832	Pelodiscus sinensis	64.71	0.00e+00	1370.00
IUUC-Pfo-097268	Poecilia formosa	89.14	0.00e+00	1920.00
IUUC-Pab-098249	Pongo abelii	65.09	0.00e+00	1342.00
IUUC-Pca-100855	Procavia capensis	58.29	0.00e+00	849.00
IUUC-Pva-102506	Pteropus vampyrus	59.05	0.00e+00	1149.00
IUUC-Rno-105242	Rattus norvegicus	64.61	0.00e+00	1380.00
IUUC-Sit-110415	Setaria italica	35.52	1.00e-53	203.00
IUUC-Sar-113612	Sorex araneus	72.08	3.00e-157	549.00
IUUC-Ssc-115473	Sus scrofa	65.37	0.00e+00	1345.00
IUUC-Tgu-116974	Taeniopygia guttata	66.07	0.00e+00	1342.00
IUUC-Tru-118077	Takifugu rubripes	84.40	0.00e+00	1794.00
IUUC-Tsy-119619	Tarsius syrichta	55.50	0.00e+00	1134.00
IUUC-Tni-120807	Tetraodon nigroviridis	85.08	0.00e+00	1808.00
IUUC-Tbe-127640	Tupaia belangeri	62.86	0.00e+00	1261.00
IUUC-Ttr-129172	Tursiops truncatus	64.99	0.00e+00	1332.00
IUUC-Xtr-132194	Xenopus tropicalis	58.25	0.00e+00	1120.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence