iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088682

Ensembl Protein ID

ENSOGAP00000007880.2

UniProt Accession

H0WZ82; H0WZ82_OTOGA

Genbank Protein ID

ENSOGAP00000007880

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03095903

Gene Name

DENND3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000008776.2	ENSOGAT00000008788.2	ENSOGAP00000007880.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.80e-06	26.3	1069	1107

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sd..tllvsGsdDgtikvWDlrtgvl 35
           H +svt+l     ++  + + s+s Dgt+  W+++t ++
   Q: 1069 HRSSVTGLLVpstQTvpREVYSCSLDGTVLAWNVSTLRV 1107
           99*****955866223355**************998765 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAEAALQQLS LPSGLLELCA LLGASRDSLR GLEQVAQKKG LKNLSSLDPE VLSVFVPPFV 60
SKEDSQVAGA NCATLGKGRR RSFRKKRDRP KPEHWRGLPE DPKVLDSEEV SVPGGVDLLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGAGG CTGCGCTGCA GCAGCTGTCG CTGCCCTCGG GGCTGCTGGA ACTGTGCGCG 60
CTGCTGGGAG CCTCCCGGGA CAGCCTCCGA GGCCTGGAGC AGGTAGGGGC CGGCGGGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR005112--dDENN_dom
IPR001194--DENN_dom
IPR005113--uDENN_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50947--DDENN
PS50211--DENN
PS50946--UDENN
PS00678--WD_REPEATS_1

Pfam

PF02141--DENN
PF03456--uDENN

SMART

SM00801--dDENN
SM00799--DENN
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0017112--F:Rab guanyl-nucleotide exchange factor activity
GO:0044257--P:cellular protein catabolic process
GO:0008333--P:endosome to lysosome transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002428	Ailuropoda melanoleuca	80.45	0.00e+00	1977.00
IUUC-Ame-011614	Astyanax mexicanus	53.89	0.00e+00	1384.00
IUUC-Cfa-021105	Canis familiaris	80.08	0.00e+00	1977.00
IUUC-Csv-025827	Ciona savignyi	22.12	2.00e-04	42.40
IUUC-Dor-030471	Dipodomys ordii	79.82	0.00e+00	1046.00
IUUC-Gmo-039067	Gadus morhua	51.72	6.00e-110	392.00
IUUC-Gac-042139	Gasterosteus aculeatus	50.86	0.00e+00	1216.00
IUUC-Hsa-046572	Homo sapiens	80.86	0.00e+00	1956.00
IUUC-Loc-052634	Lepisosteus oculatus	56.94	0.00e+00	1506.00
IUUC-Mcc-055358	Macaca mulatta	82.10	0.00e+00	2045.00
IUUC-Mmr-060775	Microcebus murinus	87.00	0.00e+00	2255.00
IUUC-Mmu-063704	Mus musculus	79.52	0.00e+00	2028.00
IUUC-Ont-072676	Oreochromis niloticus	51.16	0.00e+00	1291.00
IUUC-Oni-082213	Oryza nivara	26.67	3.00e-20	94.70
IUUC-Olu-087744	Ostreococcus lucimarinus	24.55	1.00e-10	62.40
IUUC-Ptr-090684	Pan troglodytes	80.90	0.00e+00	1877.00
IUUC-Pan-092645	Papio anubis	82.74	0.00e+00	2060.00
IUUC-Pfo-096475	Poecilia formosa	52.29	0.00e+00	1276.00
IUUC-Ppe-101883	Prunus persica	26.03	6.00e-19	89.70
IUUC-Rno-105167	Rattus norvegicus	79.44	0.00e+00	1989.00
IUUC-Ssc-115459	Sus scrofa	75.00	3.00e-107	380.00
IUUC-Tru-118373	Takifugu rubripes	26.67	6.00e-15	77.00
IUUC-Tni-119750	Tetraodon nigroviridis	23.10	7.00e-15	76.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence