KW-0021--Allosteric enzyme
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0342--GTP-binding
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0783--Tetrahydrobiopterin biosynthesis
KW-0862--Zinc

IPR001474--GTP_CycHdrlase_I
IPR018234--GTP_CycHdrlase_I_CS
IPR020602--GTP_CycHdrlase_I_dom

PS00859--GTP_CYCLOHYDROL_1_1
PS00860--GTP_CYCLOHYDROL_1_2

PF01227--GTP_cyclohydroI

GO:0005737--C:cytoplasm
GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0043234--C:protein complex
GO:0005509--F:calcium ion binding
GO:0050662--F:coenzyme binding
GO:0005525--F:GTP binding
GO:0003934--F:GTP cyclohydrolase I activity
GO:0051019--F:mitogen-activated protein kinase binding
GO:0042803--F:protein homodimerization activity
GO:0008270--F:zinc ion binding
GO:0035998--P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process
GO:0071222--P:cellular response to lipopolysaccharide
GO:0042416--P:dopamine biosynthetic process
GO:0045776--P:negative regulation of blood pressure
GO:0050884--P:neuromuscular process controlling posture
GO:0010460--P:positive regulation of heart rate
GO:0051000--P:positive regulation of nitric-oxide synthase activity
GO:0051291--P:protein heterooligomerization
GO:0051260--P:protein homooligomerization
GO:0042559--P:pteridine-containing compound biosynthetic process
GO:0008217--P:regulation of blood pressure
GO:0014916--P:regulation of lung blood pressure
GO:2000121--P:regulation of removal of superoxide radicals
GO:1905627--P:regulation of serotonin biosynthetic process
GO:0034341--P:response to interferon-gamma
GO:0048265--P:response to pain
GO:0034612--P:response to tumor necrosis factor
GO:0006729--P:tetrahydrobiopterin biosynthetic process
GO:0046654--P:tetrahydrofolate biosynthetic process
GO:0042311--P:vasodilation