iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093216

Ensembl Protein ID

ENSPSIP00000005405.1

UniProt Accession

K7FBJ5; K7FBJ5_PELSI

Genbank Protein ID

ENSPSIP00000005405

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01034049

Gene Name

USP21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000005034.1	ENSPSIT00000005436.1	ENSPSIP00000005405.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.10e-95	318.8	325	663

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           Gl+NlgNtC+mN+vLQcLs++++lr+++l  ++ ++ + +  +   +el++++++++++lw  ++++av+p +++++++k+ ++f+gy+
   Q: 325  GLRNLGNTCFMNAVLQCLSSTKPLRDYCLLkEFLQEQPGT--SRAPQELTEAFADVINSLWhPDSTEAVNPARFKAVFQKYVPSFTGYS 411
           9*************************99883455555544..55778**************888999********************** PP
   S: 89   qqDaqEflaflldqleeelkk.........eknkpkeeeeeedkselsde...............aeekkkkknkslisdlFqgqlksq 153
           qqDaqEfl+fl+d+l+ e+++         +         +++  +                    +++  ++++s i+dlF gqlks 
   Q: 412  QQDAQEFLKFLMDRLHVEINRkgrktpsilS---------DTKWPS---VledadplsdderanlMWKRYLEREDSKIVDLFVGQLKSC 488
           *******************885554444431.........333222...1223455555567777************************ PP
   S: 154  ikclecdnvssreepfldlslpvpgkeet.kkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfse 241
           +kc++c+ +s+++e f+dlslp+p+k     k sl dc++ ftkeeel+ en+  c+kc+++++++kkl+++++P++L+lhL+Rf  s 
   Q: 489  LKCQACGYRSTTFEVFCDLSLPIPKKGFAgGKVSLLDCFSLFTKEEELDLENAPVCDKCRQRTRSTKKLTIQRFPRILVLHLNRF--ST 575
           ************************887541456****************************************************..66 PP
   S: 242  eqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgst 329
           +++s +k++  v+fpl+ L+l++f +++      +  Y+L+a ++HsGs++ GHY+a++++ + +W  ++Ds+V++++e++v +   s+
   Q: 576  TRYSIKKCSVFVDFPLQrLNLKEFASEKAG----NPVYKLYALCNHSGSVHYGHYTAFCRD-QSGWRVYNDSRVSPLSENQVPS---SE 656
           77899***********99*******99554....78*************************.777*******************...** PP
   S: 330  aYvlfYk 336
           +YvlfY+
   Q: 657  GYVLFYE 663
           ******8 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MGACACIILS CVLGPQPMGI STWTATAEGC ELGAGGEETL AACERVLLAI VSTMPQASEH 60
RVSRTREQII TSQPKATTKL LNGHRAVSQE RHASASPALA NGLSMAPKIR PLPPRPIPLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGAGCCT GTGCCTGCAT CATCCTATCT TGTGTTCTAG GGCCCCAGCC AATGGGAATC 60
TCCACCTGGA CAGCCACCGC CGAGGGGTGT GAGCTTGGTG CTGGTGGGGA AGAGACGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0019784--F:NEDD8-specific protease activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001858	Ailuropoda melanoleuca	58.51	0.00e+00	637.00
IUUC-Aca-004612	Anolis carolinensis	73.10	0.00e+00	822.00
IUUC-Ago-007959	Ashbya gossypii	31.92	8.00e-46	178.00
IUUC-Acl-008102	Aspergillus clavatus	30.65	2.00e-42	167.00
IUUC-Afl-008604	Aspergillus flavus	29.38	4.00e-40	159.00
IUUC-Afu-009001	Aspergillus fumigatus	30.00	4.00e-42	166.00
IUUC-Ani-009291	Aspergillus nidulans	30.13	3.00e-41	163.00
IUUC-Ang-009844	Aspergillus niger	30.54	1.00e-41	164.00
IUUC-Aor-010098	Aspergillus oryzae	29.38	3.00e-40	159.00
IUUC-Ate-010585	Aspergillus terreus	30.35	4.00e-41	163.00
IUUC-Bta-012626	Bos taurus	58.44	5.00e-180	624.00
IUUC-Bol-015281	Brassica oleracea	33.87	3.00e-49	189.00
IUUC-Bra-016678	Brassica rapa	34.13	6.00e-49	188.00
IUUC-Cja-018853	Callithrix jacchus	59.78	0.00e+00	643.00
IUUC-Cfa-021167	Canis familiaris	58.51	0.00e+00	629.00
IUUC-Cpo-021305	Cavia porcellus	59.74	0.00e+00	640.00
IUUC-Csa-023454	Chlorocebus sabaeus	60.10	0.00e+00	644.00
IUUC-Cho-024836	Choloepus hoffmanni	83.24	2.00e-89	322.00
IUUC-Cin-025797	Ciona intestinalis	45.66	4.00e-84	304.00
IUUC-Csv-026132	Ciona savignyi	43.43	7.00e-84	304.00
IUUC-Cne-026821	Cryptococcus neoformans	36.22	1.00e-62	234.00
IUUC-Dre-028454	Danio rerio	53.71	3.00e-110	391.00
IUUC-Dor-031053	Dipodomys ordii	60.48	0.00e+00	670.00
IUUC-Dse-031463	Dothistroma septosporum	31.22	2.00e-38	154.00
IUUC-Dme-032208	Drosophila melanogaster	42.86	3.00e-69	256.00
IUUC-Ete-032416	Echinops telfairi	79.62	7.00e-121	427.00
IUUC-Eca-033817	Equus caballus	58.35	0.00e+00	641.00
IUUC-Fca-036400	Felis catus	59.34	0.00e+00	634.00
IUUC-Gmo-038926	Gadus morhua	54.44	2.00e-105	375.00
IUUC-Gac-041331	Gasterosteus aculeatus	53.16	1.00e-108	385.00
IUUC-Ggo-045174	Gorilla gorilla	60.10	0.00e+00	644.00
IUUC-Hsa-046443	Homo sapiens	60.42	0.00e+00	639.00
IUUC-Itr-048329	Ictidomys tridecemlineatus	59.02	0.00e+00	645.00
IUUC-Kpa-049321	Komagataella pastoris	31.69	2.00e-40	160.00
IUUC-Lch-050539	Latimeria chalumnae	69.59	1.00e-119	423.00
IUUC-Loc-051808	Lepisosteus oculatus	55.68	7.00e-118	416.00
IUUC-Lma-053021	Leptosphaeria maculans	31.81	5.00e-47	182.00
IUUC-Laf-053730	Loxodonta africana	58.86	0.00e+00	649.00
IUUC-Mcc-055541	Macaca mulatta	60.10	0.00e+00	644.00
IUUC-Meu-056279	Macropus eugenii	60.90	0.00e+00	669.00
IUUC-Mla-059089	Melampsora laricipopulina	37.13	3.00e-51	197.00
IUUC-Mvi-060559	Microbotryum violaceum	35.36	1.00e-55	212.00
IUUC-Mmr-060913	Microcebus murinus	59.62	0.00e+00	627.00
IUUC-Mdo-061807	Monodelphis domestica	58.84	0.00e+00	641.00
IUUC-Mmu-063599	Mus musculus	65.33	6.00e-177	613.00
IUUC-Mpu-066329	Mustela putorius furo	58.51	0.00e+00	629.00
IUUC-Mlu-067359	Myotis lucifugus	56.04	1.00e-161	562.00
IUUC-Nfi-068410	Neosartorya fischeri	30.00	1.00e-41	165.00
IUUC-Nle-070084	Nomascus leucogenys	59.39	7.00e-178	616.00
IUUC-Opr-071096	Ochotona princeps	58.97	6.00e-178	617.00
IUUC-Ocu-074228	Oryctolagus cuniculus	58.70	0.00e+00	637.00
IUUC-Ola-086684	Oryzias latipes	51.15	3.00e-104	371.00
IUUC-Oga-088007	Otolemur garnettii	55.71	2.00e-136	478.00
IUUC-Oar-090226	Ovis aries	57.58	9.00e-135	473.00
IUUC-Ptr-091522	Pan troglodytes	60.10	0.00e+00	644.00
IUUC-Pan-091954	Papio anubis	59.78	0.00e+00	637.00
IUUC-Pno-094986	Phaeosphaeria nodorum	30.68	3.00e-36	146.00
IUUC-Pab-098691	Pongo abelii	60.10	0.00e+00	644.00
IUUC-Pca-101133	Procavia capensis	54.37	1.00e-163	569.00
IUUC-Pva-102681	Pteropus vampyrus	56.85	2.00e-174	605.00
IUUC-Pte-104348	Pyrenophora teres	31.01	2.00e-39	157.00
IUUC-Pyt-104711	Pyrenophora triticirepentis	32.32	4.00e-47	183.00
IUUC-Rno-105132	Rattus norvegicus	58.12	0.00e+00	630.00
IUUC-Sce-106435	Saccharomyces cerevisiae	33.66	1.00e-48	187.00
IUUC-Sha-107145	Sarcophilus harrisii	58.09	3.00e-177	614.00
IUUC-Sja-107836	Schizosaccharomyces japonicus	32.77	2.00e-39	157.00
IUUC-Spo-108065	Schizosaccharomyces pombe	30.48	1.00e-33	137.00
IUUC-Smo-109021	Selaginella moellendorffii	33.89	3.00e-46	178.00
IUUC-Sre-115031	Sporisorium reilianum	35.64	1.00e-56	215.00
IUUC-Ssc-115586	Sus scrofa	58.82	1.00e-180	625.00
IUUC-Tgu-117491	Taeniopygia guttata	89.41	3.00e-125	439.00
IUUC-Tni-120746	Tetraodon nigroviridis	52.08	6.00e-99	353.00
IUUC-Tme-127144	Tuber melanosporum	35.75	4.00e-59	223.00
IUUC-Tbe-127465	Tupaia belangeri	87.92	2.00e-110	392.00
IUUC-Ttr-128274	Tursiops truncatus	56.92	3.00e-171	594.00
IUUC-Uma-129340	Ustilago maydis	33.80	6.00e-55	209.00
IUUC-Xtr-131989	Xenopus tropicalis	78.50	3.00e-138	484.00
IUUC-Yli-134561	Yarrowia lipolytica	32.70	6.00e-46	179.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence