iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Spo-108151

UUCD1 version

UUC-ScP-00224

Ensembl Protein ID

SPBC106.09.1:pep

UniProt Accession

Q9URV2; O13457; APC1_SCHPO

Genbank Protein ID

BAA22618.1; CAB53725.1

Protein Name

Anaphase-promoting complex subunit 1; 20S cyclosome/APC complex protein apc1; Cell untimely torn protein 4

Genbank Nucleotide ID

D85196; CU329671

Gene Name

cut4; apc1; SPBC106.09

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPBC106.09	SPBC106.09.1	SPBC106.09.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT	Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/APC_C/APC_C	27.77	2.00e-61	233.00	IUUC-Sce-106246

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. Mutations to this protein prevent the exit from mitosis.

Protein Sequence
(Fasta)

MLELKTNVIQ DPELKDSLDL QENDRVEIIG DAVHYIVNDH LNRVFNYTVD QQKIHAALIT 60
TFASGKKAIV VILDDIGYVY YVGDNNNDSY IINVPFSTES AWSSPSGLYL QRHRSSDENL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTAAAAAGGA AATGCGAAAT TGTAAACGGA ACTGAGTTAT TGATTATCGT TACTAGATGC 60
TGAAATGCTA GAATTAAAAA CAAATGTTAT TCAAGACCCT GAATTAAAGG ATTCATTAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway

Interpro

IPR024990--Apc1

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0005829--C:cytosol
GO:0031618--C:nuclear pericentric heterochromatin
GO:0005634--C:nucleus
GO:0070628--F:proteasome binding
GO:0051301--P:cell division
GO:0007067--P:mitotic nuclear division

KEGG

spo:SPBC106.09

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002294	Ailuropoda melanoleuca	30.60	4.00e-117	415.00
IUUC-Atr-002881	Amborella trichopoda	29.87	4.00e-80	291.00
IUUC-Apl-003588	Anas platyrhynchos	32.38	3.00e-119	422.00
IUUC-Aca-005361	Anolis carolinensis	29.59	6.00e-115	407.00
IUUC-Aly-005680	Arabidopsis lyrata	27.39	2.00e-78	286.00
IUUC-Ath-007479	Arabidopsis thaliana	29.38	2.00e-91	329.00
IUUC-Ago-007943	Ashbya gossypii	26.65	3.00e-60	226.00
IUUC-Acl-008141	Aspergillus clavatus	40.00	5.00e-173	600.00
IUUC-Afl-008487	Aspergillus flavus	39.31	1.00e-166	579.00
IUUC-Afu-008897	Aspergillus fumigatus	40.07	3.00e-176	611.00
IUUC-Ani-009232	Aspergillus nidulans	39.71	4.00e-162	564.00
IUUC-Ang-009699	Aspergillus niger	39.42	7.00e-156	543.00
IUUC-Aor-009943	Aspergillus oryzae	39.26	1.00e-166	579.00
IUUC-Ate-010554	Aspergillus terreus	40.16	3.00e-162	565.00
IUUC-Ame-011373	Astyanax mexicanus	31.09	3.00e-127	448.00
IUUC-Bgr-011994	Blumeria graminis	35.36	7.00e-156	543.00
IUUC-Bta-013227	Bos taurus	30.51	5.00e-110	391.00
IUUC-Bci-013591	Botrytis cinerea	35.65	2.00e-171	595.00
IUUC-Bdi-015048	Brachypodium distachyon	31.04	6.00e-67	247.00
IUUC-Bol-016448	Brassica oleracea	29.02	3.00e-85	308.00
IUUC-Bra-017688	Brassica rapa	26.85	5.00e-63	234.00
IUUC-Cel-018707	Caenorhabditis elegans	27.77	4.00e-61	228.00
IUUC-Cja-019608	Callithrix jacchus	30.78	4.00e-116	411.00
IUUC-Cfa-021133	Canis familiaris	30.82	3.00e-118	418.00
IUUC-Cpo-022097	Cavia porcellus	30.42	1.00e-114	406.00
IUUC-Cre-022722	Chlamydomonas reinhardtii	30.11	4.00e-27	114.00
IUUC-Csa-024077	Chlorocebus sabaeus	31.04	8.00e-118	417.00
IUUC-Cho-024372	Choloepus hoffmanni	43.06	3.00e-41	162.00
IUUC-Cin-025169	Ciona intestinalis	33.72	3.00e-46	176.00
IUUC-Csv-026053	Ciona savignyi	29.84	7.00e-27	114.00
IUUC-Cgl-026415	Colletotrichum gloeosporioides	36.46	1.00e-156	546.00
IUUC-Cne-026772	Cryptococcus neoformans	34.41	2.00e-96	345.00
IUUC-Cme-027221	Cyanidioschyzon merolae	29.10	6.00e-10	59.30
IUUC-Dre-028168	Danio rerio	33.01	6.00e-128	451.00
IUUC-Dno-029251	Dasypus novemcinctus	30.57	3.00e-116	411.00
IUUC-Dor-031058	Dipodomys ordii	40.00	5.00e-51	195.00
IUUC-Dse-031374	Dothistroma septosporum	36.93	2.00e-119	421.00
IUUC-Dme-031637	Drosophila melanogaster	35.83	2.00e-113	402.00
IUUC-Ete-032785	Echinops telfairi	33.90	2.00e-92	333.00
IUUC-Eca-034301	Equus caballus	30.93	2.00e-117	416.00
IUUC-Eeu-034448	Erinaceus europaeus	31.31	1.00e-65	244.00
IUUC-Fca-036327	Felis catus	30.96	1.00e-117	417.00
IUUC-Fal-037242	Ficedula albicollis	32.10	2.00e-117	416.00
IUUC-Fox-037815	Fusarium oxysporum	41.25	8.00e-74	271.00
IUUC-Fso-038155	Fusarium solani	36.55	3.00e-158	551.00
IUUC-Gmo-039055	Gadus morhua	33.46	4.00e-101	361.00
IUUC-Ggr-039950	Gaeumannomyces graminis	37.09	7.00e-148	517.00
IUUC-Gga-040699	Gallus gallus	31.85	3.00e-118	419.00
IUUC-Gac-041384	Gasterosteus aculeatus	35.10	4.00e-112	398.00
IUUC-Gma-043887	Glycine max	28.65	2.00e-89	322.00
IUUC-Hsa-045774	Homo sapiens	31.04	1.00e-118	420.00
IUUC-Hvu-047197	Hordeum vulgare	28.17	1.00e-53	202.00
IUUC-Itr-048307	Ictidomys tridecemlineatus	32.53	8.00e-117	414.00
IUUC-Kpa-049213	Komagataella pastoris	35.71	4.00e-145	507.00
IUUC-Lch-050625	Latimeria chalumnae	30.19	9.00e-122	430.00
IUUC-Lpe-050901	Leersia perrieri	25.98	6.00e-71	261.00
IUUC-Loc-052539	Lepisosteus oculatus	37.39	6.00e-115	406.00
IUUC-Lma-052970	Leptosphaeria maculans	35.11	7.00e-144	503.00
IUUC-Laf-054144	Loxodonta africana	30.61	7.00e-118	417.00
IUUC-Mcc-054940	Macaca mulatta	31.04	8.00e-118	417.00
IUUC-Mor-057218	Magnaporthe oryzae	37.66	5.00e-153	534.00
IUUC-Mtr-058775	Medicago truncatula	30.33	4.00e-93	335.00
IUUC-Mla-059122	Melampsora laricipopulina	29.29	4.00e-101	362.00
IUUC-Mga-059663	Meleagris gallopavo	31.72	2.00e-118	419.00
IUUC-Mvi-060259	Microbotryum violaceum	31.32	5.00e-95	341.00
IUUC-Mmr-060620	Microcebus murinus	29.63	3.00e-116	412.00
IUUC-Mdo-062149	Monodelphis domestica	32.43	1.00e-118	419.00
IUUC-Mmu-063698	Mus musculus	30.86	3.00e-117	415.00
IUUC-Mac-065285	Musa acuminata	34.86	1.00e-72	265.00
IUUC-Mpu-066489	Mustela putorius furo	30.70	3.00e-118	418.00
IUUC-Mlu-067969	Myotis lucifugus	31.43	4.00e-118	418.00
IUUC-Nfi-068325	Neosartorya fischeri	39.91	6.00e-174	603.00
IUUC-Ncr-068817	Neurospora crassa	37.44	1.00e-147	516.00
IUUC-Nle-069961	Nomascus leucogenys	30.96	5.00e-118	417.00
IUUC-Opr-071086	Ochotona princeps	38.59	4.00e-58	218.00
IUUC-Ont-071831	Oreochromis niloticus	32.18	4.00e-116	411.00
IUUC-Oan-073375	Ornithorhynchus anatinus	28.37	6.00e-24	103.00
IUUC-Ocu-073892	Oryctolagus cuniculus	30.96	4.00e-117	415.00
IUUC-Oba-075880	Oryza barthii	27.02	7.00e-54	204.00
IUUC-Obr-076384	Oryza brachyantha	29.11	6.00e-73	268.00
IUUC-Ogl-077165	Oryza glaberrima	31.62	2.00e-72	265.00
IUUC-Ogu-078764	Oryza glumaepatula	24.81	1.00e-44	174.00
IUUC-Oin-079711	Oryza indica	28.11	4.00e-75	275.00
IUUC-Olo-080715	Oryza longistaminata	34.10	1.00e-54	207.00
IUUC-Ome-081131	Oryza meridionalis	26.54	1.00e-51	196.00
IUUC-Oni-082223	Oryza nivara	24.92	2.00e-41	163.00
IUUC-Opu-083985	Oryza punctata	28.78	3.00e-73	269.00
IUUC-Oru-085031	Oryza rufipogon	24.65	2.00e-42	166.00
IUUC-Osa-085599	Oryza sativa	32.72	2.00e-70	259.00
IUUC-Ola-087375	Oryzias latipes	30.96	3.00e-120	425.00
IUUC-Olu-087875	Ostreococcus lucimarinus	36.26	2.00e-51	196.00
IUUC-Oga-088815	Otolemur garnettii	32.90	6.00e-117	414.00
IUUC-Oar-090326	Ovis aries	30.58	2.00e-110	392.00
IUUC-Ptr-091143	Pan troglodytes	30.87	9.00e-118	417.00
IUUC-Pan-091945	Papio anubis	31.04	9.00e-118	417.00
IUUC-Psi-092955	Pelodiscus sinensis	33.49	1.00e-56	213.00
IUUC-Pma-094473	Petromyzon marinus	33.97	1.00e-98	353.00
IUUC-Pno-094991	Phaeosphaeria nodorum	44.31	2.00e-145	507.00
IUUC-Ppa-095617	Physcomitrella patens	32.49	3.00e-65	242.00
IUUC-Pfo-096119	Poecilia formosa	33.69	1.00e-126	446.00
IUUC-Pab-098265	Pongo abelii	32.67	4.00e-115	408.00
IUUC-Pop-099429	Populus trichocarpa	32.33	6.00e-85	308.00
IUUC-Pca-100116	Procavia capensis	33.25	7.00e-51	194.00
IUUC-Ppe-102034	Prunus persica	34.30	1.00e-89	322.00
IUUC-Pva-102425	Pteropus vampyrus	29.46	1.00e-85	310.00
IUUC-Pgr-103486	Puccinia graminis	31.91	1.00e-92	333.00
IUUC-Pte-104231	Pyrenophora teres	36.11	8.00e-145	507.00
IUUC-Pyt-104725	Pyrenophora triticirepentis	37.17	4.00e-154	538.00
IUUC-Rno-106106	Rattus norvegicus	30.45	8.00e-116	410.00
IUUC-Sce-106246	Saccharomyces cerevisiae	28.29	1.00e-60	227.00
IUUC-Sha-107371	Sarcophilus harrisii	32.51	3.00e-102	365.00
IUUC-Sja-107837	Schizosaccharomyces japonicus	48.76	0.00e+00	1055.00
IUUC-Smo-109131	Selaginella moellendorffii	31.27	5.00e-77	281.00
IUUC-Sit-109833	Setaria italica	32.27	1.00e-50	192.00
IUUC-Sly-111174	Solanum lycopersicum	32.99	4.00e-79	287.00
IUUC-Sar-113322	Sorex araneus	34.20	1.00e-33	137.00
IUUC-Sre-115207	Sporisorium reilianum	29.79	1.00e-86	313.00
IUUC-Ssc-115572	Sus scrofa	30.36	2.00e-117	415.00
IUUC-Tgu-117040	Taeniopygia guttata	32.73	2.00e-122	432.00
IUUC-Tru-118159	Takifugu rubripes	32.80	2.00e-120	426.00
IUUC-Tsy-119288	Tarsius syrichta	36.20	6.00e-73	268.00
IUUC-Tni-119889	Tetraodon nigroviridis	30.06	3.00e-41	162.00
IUUC-Tca-120982	Theobroma cacao	28.36	1.00e-80	293.00
IUUC-Tre-122017	Trichoderma reesei	37.30	9.00e-163	566.00
IUUC-Tvi-122340	Trichoderma virens	37.43	1.00e-164	572.00
IUUC-Tae-122989	Triticum aestivum	29.25	6.00e-87	314.00
IUUC-Tme-127169	Tuber melanosporum	38.11	4.00e-180	624.00
IUUC-Tbe-127596	Tupaia belangeri	23.13	2.30e-02	33.90
IUUC-Ttr-128376	Tursiops truncatus	32.42	8.00e-109	387.00
IUUC-Uma-129513	Ustilago maydis	30.03	7.00e-80	291.00
IUUC-Vda-129898	Verticillium dahliae	35.08	7.00e-127	447.00
IUUC-Vpa-130495	Vicugna pacos	32.79	2.00e-113	402.00
IUUC-Vvi-131656	Vitis vinifera	35.64	2.00e-80	291.00
IUUC-Xtr-132770	Xenopus tropicalis	34.69	1.00e-109	390.00
IUUC-Xma-133490	Xiphophorus maculatus	39.44	4.00e-103	367.00
IUUC-Yli-134525	Yarrowia lipolytica	37.31	4.00e-153	534.00
IUUC-Zma-134774	Zea mays	26.09	5.00e-54	204.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence