iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	Mentha
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box	F-box	18340346

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	1.60e-08	34.7	323	412

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 52   rrasrrtprqp.prgpsaaakpkaglrseaaaapapapaptptpeegpdaglldrlpeeilveilklldkeellraarvcrrwqelasqkalwktvt 147
           r+ srr   q    gpsa a   a     aa+  a   apt      + + l+ +lp+e+l+ i+++l +++l+r+a+vc+r++++a++++lwk+++
   Q: 323  RKRSRRLYTQGgEMGPSAGATGEAAGAGTAASGGA-GCAPT------AAQYLQYELPDEVLLAIFSYLMEQDLCRLALVCKRFNTIANDTELWKRLY 412
           45566665554156777777666554444333333.33444......4578999***************************************9976 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MPSASFTSSR TYVRRSRRKG ANRIAMPNRP TGNIMDPMLQ QNVTAAGAGA SASGSNSNAA 60
SSSGAGGVGN NNASSSGSSG ATSTSGSAAA AASAAGPTAA GASSSAEYFD SGQGASGSSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTTCCATC AGTCGAGCAG CGGTCACTCT CAACGCTAAA ATTAAAACTC CGAGTATAGG 60
TGGTTTCGCT TCTGAAATTT TGGAATAAAA GTGTTCAATT GTGTCAAGTG CACAAGCTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006633--Carb-bd_sugar_hydrolysis-dom
IPR001810--F-box_dom
IPR029799--FBX11/DRE-1
IPR007742--NosD_dom
IPR022441--Para_beta_helix_rpt-2
IPR006626--PbH1
IPR012334--Pectin_lyas_fold
IPR011050--Pectin_lyase_fold/virulence
IPR003126--Znf_UBR

PROSITE

PS50181--FBOX
PS51157--ZF_UBR

Pfam

PF12937--F-box-like
PF05048--NosD
PF02207--zf-UBR

SMART

SM00722--CASH
SM00256--FBOX
SM00710--PbH1
SM00396--ZnF_UBR1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination
GO:0060966--P:regulation of gene silencing by RNA
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0070923--P:siRNA loading onto RISC involved in chromatin silencing by small RNA
GO:0030431--P:sleep

KEGG

dme:Dmel_CG9461

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002291	Ailuropoda melanoleuca	69.12	0.00e+00	1177.00
IUUC-Apl-003412	Anas platyrhynchos	69.29	0.00e+00	1182.00
IUUC-Aca-004842	Anolis carolinensis	69.17	0.00e+00	1179.00
IUUC-Ago-007783	Ashbya gossypii	53.49	5.00e-07	48.90
IUUC-Ame-010687	Astyanax mexicanus	69.53	0.00e+00	1183.00
IUUC-Bgr-012114	Blumeria graminis	40.43	3.00e-05	43.50
IUUC-Bta-013526	Bos taurus	64.60	0.00e+00	782.00
IUUC-Cel-018135	Caenorhabditis elegans	57.18	0.00e+00	962.00
IUUC-Cja-019156	Callithrix jacchus	69.41	0.00e+00	1182.00
IUUC-Cfa-020503	Canis familiaris	69.29	0.00e+00	1181.00
IUUC-Cpo-022148	Cavia porcellus	69.29	0.00e+00	1181.00
IUUC-Csa-023799	Chlorocebus sabaeus	69.41	0.00e+00	1182.00
IUUC-Cho-024925	Choloepus hoffmanni	67.61	0.00e+00	1053.00
IUUC-Cin-025649	Ciona intestinalis	64.58	0.00e+00	1095.00
IUUC-Csv-026010	Ciona savignyi	64.99	0.00e+00	1071.00
IUUC-Cgl-026674	Colletotrichum gloeosporioides	42.59	9.00e-07	47.80
IUUC-Dre-027862	Danio rerio	69.41	0.00e+00	1185.00
IUUC-Dno-029555	Dasypus novemcinctus	69.00	0.00e+00	1170.00
IUUC-Dor-030610	Dipodomys ordii	63.89	0.00e+00	1000.00
IUUC-Ete-032999	Echinops telfairi	66.14	0.00e+00	1108.00
IUUC-Eca-033942	Equus caballus	69.29	0.00e+00	1183.00
IUUC-Eeu-034872	Erinaceus europaeus	69.17	0.00e+00	1176.00
IUUC-Fca-035904	Felis catus	68.03	0.00e+00	1150.00
IUUC-Fal-036742	Ficedula albicollis	69.29	0.00e+00	1182.00
IUUC-Fso-038235	Fusarium solani	46.00	4.00e-07	48.90
IUUC-Gmo-039082	Gadus morhua	68.92	0.00e+00	1176.00
IUUC-Ggr-039881	Gaeumannomyces graminis	43.48	8.00e-05	41.60
IUUC-Gga-040292	Gallus gallus	69.29	0.00e+00	1183.00
IUUC-Gac-042106	Gasterosteus aculeatus	69.29	0.00e+00	1181.00
IUUC-Ggo-045283	Gorilla gorilla	69.41	0.00e+00	1182.00
IUUC-Hsa-046244	Homo sapiens	69.41	0.00e+00	1182.00
IUUC-Itr-047990	Ictidomys tridecemlineatus	69.29	0.00e+00	1182.00
IUUC-Kpa-049204	Komagataella pastoris	48.94	1.00e-07	51.20
IUUC-Lch-049831	Latimeria chalumnae	68.92	0.00e+00	1183.00
IUUC-Loc-051875	Lepisosteus oculatus	69.29	0.00e+00	1183.00
IUUC-Laf-053642	Loxodonta africana	69.29	0.00e+00	1176.00
IUUC-Mcc-055761	Macaca mulatta	69.41	0.00e+00	1181.00
IUUC-Meu-056886	Macropus eugenii	63.56	0.00e+00	727.00
IUUC-Mga-059470	Meleagris gallopavo	69.29	0.00e+00	1182.00
IUUC-Mmr-060959	Microcebus murinus	69.29	0.00e+00	1182.00
IUUC-Mdo-062165	Monodelphis domestica	69.29	0.00e+00	1181.00
IUUC-Mmu-063590	Mus musculus	69.29	0.00e+00	1182.00
IUUC-Mpu-066702	Mustela putorius furo	69.29	0.00e+00	1182.00
IUUC-Mlu-067906	Myotis lucifugus	68.95	0.00e+00	1171.00
IUUC-Nle-069878	Nomascus leucogenys	69.41	0.00e+00	1182.00
IUUC-Opr-070211	Ochotona princeps	50.82	9.00e-104	370.00
IUUC-Ont-072251	Oreochromis niloticus	68.92	0.00e+00	1178.00
IUUC-Oan-073077	Ornithorhynchus anatinus	60.79	0.00e+00	790.00
IUUC-Ocu-074419	Oryctolagus cuniculus	69.17	0.00e+00	1175.00
IUUC-Ola-087171	Oryzias latipes	69.00	0.00e+00	1177.00
IUUC-Oga-088010	Otolemur garnettii	69.41	0.00e+00	1177.00
IUUC-Oar-089660	Ovis aries	69.29	0.00e+00	1182.00
IUUC-Ptr-091220	Pan troglodytes	69.41	0.00e+00	1183.00
IUUC-Pan-092606	Papio anubis	77.21	0.00e+00	1050.00
IUUC-Psi-093950	Pelodiscus sinensis	69.29	0.00e+00	1184.00
IUUC-Pma-094248	Petromyzon marinus	66.51	0.00e+00	1126.00
IUUC-Pno-094906	Phaeosphaeria nodorum	31.03	5.00e-03	37.40
IUUC-Pfo-097361	Poecilia formosa	68.92	0.00e+00	1173.00
IUUC-Pab-097736	Pongo abelii	69.41	0.00e+00	1182.00
IUUC-Pca-100204	Procavia capensis	63.88	0.00e+00	1044.00
IUUC-Pva-102248	Pteropus vampyrus	63.33	0.00e+00	866.00
IUUC-Pgr-103283	Puccinia graminis	38.98	2.00e-07	50.10
IUUC-Rno-106009	Rattus norvegicus	69.29	0.00e+00	1182.00
IUUC-Sce-106294	Saccharomyces cerevisiae	33.87	7.00e-07	48.50
IUUC-Sha-107330	Sarcophilus harrisii	69.29	0.00e+00	1181.00
IUUC-Ssl-108666	Sclerotinia sclerotiorum	40.00	2.00e-04	40.40
IUUC-Stu-112725	Solanum tuberosum	36.07	1.00e-06	47.00
IUUC-Sar-112927	Sorex araneus	83.84	5.00e-170	590.00
IUUC-Sre-115181	Sporisorium reilianum	50.00	2.00e-08	53.50
IUUC-Ssc-115330	Sus scrofa	69.04	0.00e+00	1172.00
IUUC-Tgu-116883	Taeniopygia guttata	69.29	0.00e+00	1182.00
IUUC-Tru-118225	Takifugu rubripes	68.88	0.00e+00	1175.00
IUUC-Tsy-119194	Tarsius syrichta	67.16	0.00e+00	926.00
IUUC-Tni-119690	Tetraodon nigroviridis	68.83	0.00e+00	1167.00
IUUC-Tre-122100	Trichoderma reesei	48.78	2.00e-06	47.00
IUUC-Tvi-122410	Trichoderma virens	48.78	2.00e-06	47.00
IUUC-Tae-122964	Triticum aestivum	47.62	2.00e-07	48.90
IUUC-Tme-127013	Tuber melanosporum	44.68	1.00e-05	43.90
IUUC-Tbe-127560	Tupaia belangeri	74.72	2.00e-118	419.00
IUUC-Ttr-129186	Tursiops truncatus	66.51	0.00e+00	1123.00
IUUC-Uma-129621	Ustilago maydis	50.00	2.00e-08	53.90
IUUC-Vda-129904	Verticillium dahliae	40.00	2.00e-05	43.50
IUUC-Vpa-130098	Vicugna pacos	67.35	0.00e+00	1133.00
IUUC-Xtr-132162	Xenopus tropicalis	69.29	0.00e+00	1180.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence