iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.50e-07	30.7	1153	1194

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf...kdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           C+iC+e +   + +++ lpCgH++h +C+q +      ++ + +CP+C
   Q: 1153 CPICHEYIftsSSPVKALPCGHLMHSTCFQEY------TCSHYTCPVC 1194
           ******99565556999***************......********** PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Probable E3 ubiquitin-protein ligase that may regulate the response to iron deficiency and thus contributes to iron homeostasis.

Protein Sequence
(Fasta)

MGGGNLHSLP PENASVSASY AVTVGNTKLS DAPVLFFVYC HKAFRAQLVE LRRFATDAAE 60
ADSFSGDLAV ELSRKFEFLK LVYKYHSAAE DEVIFLALDK RVKNIVSNYS LEHAGTDDLF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTATCATGCC TTTAAAAACC TTCTCTACTC CTTTAATCGG TTCCTTCTTC TTTCCCTTTT 60
CTCCTTTCGC TTCACGACGA CGAAATTTTT GATTTCAGTC ACCGTTATTG TTGTTGCGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0408--Iron
KW-0436--Ligase
KW-0472--Membrane
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR012312--Haemerythrin-like
IPR004039--Rubredoxin-type_fold
IPR008913--Znf_CHY
IPR017921--Znf_CTCHY
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51266--ZF_CHY
PS51270--ZF_CTCHY
PS50089--ZF_RING_2

Pfam

PF01814--Hemerythrin
PF05495--zf-CHY
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005634--C:nucleus
GO:0016874--F:ligase activity
GO:0008270--F:zinc ion binding

KEGG

ath:AT1G74770

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006496	Arabidopsis lyrata	92.37	0.00e+00	2417.00
IUUC-Bol-016414	Brassica oleracea	78.71	0.00e+00	2022.00
IUUC-Bra-018055	Brassica rapa	79.35	0.00e+00	2034.00
IUUC-Ggr-040055	Gaeumannomyces graminis	42.62	4.00e-58	219.00
IUUC-Kpa-049272	Komagataella pastoris	37.66	1.00e-61	230.00
IUUC-Mor-057100	Magnaporthe oryzae	40.17	6.00e-57	215.00
IUUC-Mpo-057579	Magnaporthe poae	41.77	2.00e-59	223.00
IUUC-Ppe-101791	Prunus persica	50.72	0.00e+00	1232.00
IUUC-Sly-110951	Solanum lycopersicum	47.11	0.00e+00	1078.00
IUUC-Stu-112448	Solanum tuberosum	47.29	0.00e+00	1053.00
IUUC-Tca-121662	Theobroma cacao	53.18	0.00e+00	1262.00
IUUC-Tme-127113	Tuber melanosporum	40.98	1.00e-58	220.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence