iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Uma-129502

Ensembl Protein ID

KIS66336

UniProt Accession

Q4P3H6; A0A0D1DQT8; SLA1_USTMA

Genbank Protein ID

KIS66336.1

Protein Name

Actin cytoskeleton-regulatory complex protein SLA1

Genbank Nucleotide ID

CM003158

Gene Name

SLA1; UMAG_05337

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
UMAG_05337	KIS66336	KIS66336

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.30e-37	124.1	6	75

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvk.............elegkrGlfPenFvekle 63
           ++++lydy aq +deL+l++ d ++++  e+ d +W+k++               +    Gl+P+n+ve++e
   Q: 6    LCKALYDYVAQAEDELNLTEDDHLYIL--ESDDPEWWKAKLrrldehgtpiqddSDDSTVGLVPANYVEEAE 75
           79*************************..99********88***********9999999**********986 PP

Organism

Ustilago maydis

Functional Description
(View)

Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).

Protein Sequence
(Fasta)

MAYVALCKAL YDYVAQAEDE LNLTEDDHLY ILESDDPEWW KAKLRRLDEH GTPIQDDSDD 60
STVGLVPANY VEEAEPIRLS RALYDYEAQT EEELSMAEDE LLRVYESDGV WLLVKKQGND 120

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Nucleotide Sequence
(Fasta)

ATGGCGTACG TAGCGCTCTG TAAGGCGCTC TACGACTACG TAGCTCAGGC CGAGGACGAG 60
CTCAACCTTA CCGAGGATGA CCACCTCTAC ATTCTCGAGT CTGATGACCC CGAGTGGTGG 120

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Sequence Source

Ensembl

Keyword

KW-0009--Actin-binding
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0254--Endocytosis
KW-0967--Endosome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain

Interpro

IPR013182--DUF1720
IPR013761--SAM/pointed
IPR001452--SH3_domain
IPR007131--SHD1
IPR029922--Sla1

PROSITE

PS50002--SH3

Pfam

PF08226--DUF1720
PF00018--SH3_1
PF14604--SH3_9
PF03983--SHD1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0030479--C:actin cortical patch
GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0007015--P:actin filament organization
GO:0006897--P:endocytosis

KEGG

uma:UMAG_05337

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006058	Arabidopsis lyrata	51.43	1.50e-01	30.40
IUUC-Ath-006715	Arabidopsis thaliana	47.37	2.70e-02	31.20
IUUC-Ago-007979	Ashbya gossypii	52.11	7.00e-20	91.70
IUUC-Acl-008300	Aspergillus clavatus	35.54	2.00e-35	143.00
IUUC-Afl-008694	Aspergillus flavus	33.23	2.00e-38	153.00
IUUC-Afu-008881	Aspergillus fumigatus	34.14	2.00e-37	149.00
IUUC-Ani-009274	Aspergillus nidulans	33.43	4.00e-37	148.00
IUUC-Ang-009534	Aspergillus niger	32.56	5.00e-39	155.00
IUUC-Aor-010097	Aspergillus oryzae	33.53	5.00e-39	155.00
IUUC-Ate-010495	Aspergillus terreus	36.36	1.00e-21	97.80
IUUC-Bgr-012294	Blumeria graminis	33.14	1.00e-41	164.00
IUUC-Bta-013076	Bos taurus	37.93	9.00e-09	52.40
IUUC-Bci-013990	Botrytis cinerea	34.12	7.00e-32	131.00
IUUC-Cel-018144	Caenorhabditis elegans	24.00	7.00e-09	53.10
IUUC-Cja-019850	Callithrix jacchus	38.16	9.00e-10	55.80
IUUC-Cin-025348	Ciona intestinalis	42.11	6.00e-09	53.50
IUUC-Csv-026046	Ciona savignyi	26.67	2.00e-08	52.00
IUUC-Cgl-026697	Colletotrichum gloeosporioides	42.66	5.00e-24	105.00
IUUC-Cne-026842	Cryptococcus neoformans	41.30	4.00e-53	201.00
IUUC-Dse-031496	Dothistroma septosporum	31.60	2.00e-19	89.70
IUUC-Dme-032117	Drosophila melanogaster	44.26	2.00e-09	57.00
IUUC-Fal-037170	Ficedula albicollis	39.66	5.00e-09	53.50
IUUC-Fso-038358	Fusarium solani	41.28	5.00e-37	148.00
IUUC-Gmo-038783	Gadus morhua	36.05	7.00e-09	52.80
IUUC-Ggr-040032	Gaeumannomyces graminis	33.64	2.00e-40	159.00
IUUC-Kpa-049118	Komagataella pastoris	39.13	6.00e-23	101.00
IUUC-Lch-050016	Latimeria chalumnae	29.30	4.00e-10	58.20
IUUC-Loc-052916	Lepisosteus oculatus	38.10	1.00e-11	61.60
IUUC-Lma-053174	Leptosphaeria maculans	39.57	4.00e-19	86.70
IUUC-Mor-056954	Magnaporthe oryzae	32.92	6.00e-40	158.00
IUUC-Mpo-057576	Magnaporthe poae	36.07	1.00e-39	157.00
IUUC-Mla-059035	Melampsora laricipopulina	41.13	1.00e-57	216.00
IUUC-Mga-059651	Meleagris gallopavo	27.40	5.00e-11	61.60
IUUC-Mvi-060454	Microbotryum violaceum	35.20	5.00e-39	155.00
IUUC-Nfi-068406	Neosartorya fischeri	32.35	3.00e-36	145.00
IUUC-Ncr-068902	Neurospora crassa	39.57	1.00e-21	97.40
IUUC-Opr-070565	Ochotona princeps	39.47	3.00e-10	57.40
IUUC-Oan-072976	Ornithorhynchus anatinus	25.64	8.00e-09	52.80
IUUC-Oba-075752	Oryza barthii	43.10	2.00e-05	44.30
IUUC-Ola-086748	Oryzias latipes	37.50	6.00e-09	53.10
IUUC-Oar-089525	Ovis aries	35.80	4.00e-10	57.00
IUUC-Pno-094774	Phaeosphaeria nodorum	36.11	3.00e-18	86.70
IUUC-Pca-100447	Procavia capensis	36.84	2.00e-09	54.30
IUUC-Pgr-103396	Puccinia graminis	41.19	3.00e-58	218.00
IUUC-Ptt-103751	Puccinia triticina	39.30	7.00e-56	211.00
IUUC-Pte-104349	Pyrenophora teres	41.43	1.00e-23	104.00
IUUC-Pyt-104695	Pyrenophora triticirepentis	41.96	3.00e-24	106.00
IUUC-Sce-106372	Saccharomyces cerevisiae	53.85	8.00e-20	91.30
IUUC-Sja-107962	Schizosaccharomyces japonicus	31.51	1.00e-16	80.90
IUUC-Spo-108375	Schizosaccharomyces pombe	59.70	1.00e-17	84.70
IUUC-Ssl-108553	Sclerotinia sclerotiorum	34.98	9.00e-28	117.00
IUUC-Sre-115072	Sporisorium reilianum	84.93	2.00e-164	571.00
IUUC-Tru-118580	Takifugu rubripes	39.13	5.00e-10	56.60
IUUC-Tni-120434	Tetraodon nigroviridis	47.06	3.00e-09	54.30
IUUC-Tre-121912	Trichoderma reesei	38.63	1.00e-29	124.00
IUUC-Tvi-122336	Trichoderma virens	37.28	4.00e-40	158.00
IUUC-Tme-127017	Tuber melanosporum	35.21	8.00e-17	80.90
IUUC-Tbe-127931	Tupaia belangeri	45.10	9.00e-09	52.40
IUUC-Ttr-128248	Tursiops truncatus	38.16	1.00e-09	55.50
IUUC-Vda-129879	Verticillium dahliae	42.14	2.00e-21	96.70
IUUC-Vpa-130409	Vicugna pacos	30.50	1.00e-10	60.10
IUUC-Xtr-132626	Xenopus tropicalis	38.98	2.00e-09	54.30
IUUC-Yli-134528	Yarrowia lipolytica	60.87	1.00e-22	100.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence