iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065781

Ensembl Protein ID

ENSMPUP00000015937.1

UniProt Accession

M3YX77; M3YX77_MUSPF

Genbank Protein ID

ENSMPUP00000015937

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01053250

Gene Name

Trim50

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000016044.1	ENSMPUT00000016181.1	ENSMPUP00000015937.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.40e-10	40.3	12	77
E3 activity/RING/RING	3.40e-09	37.1	16	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrss...IekwlasggktcPvtrqplteedlvPnltlrrliqa 67
           + + CpI le++++P++l++G++y + +   + ++l+s  + cPv+rq++++++  Pn +l r+i+a
   Q: 12   DRLQCPICLEVFKEPMMLQCGHSYCKDClvsLSRHLDSELR-CPVCRQEVDSSSPPPNVSLARVIEA 77
           5689********************99872225799999999.*********************9986 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCle fk+ p+ l+CgH +++dCl   + l++    e rCP+Cr
   Q: 16   CPICLEVFKE-PMMLQCGHSYCKDCL---VSLSRHLDSELRCPVCR 57
           ********99.999************...677999**********8 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MAGQVSVPEL EDRLQCPICL EVFKEPMMLQ CGHSYCKDCL VSLSRHLDSE LRCPVCRQEV 60
DSSSPPPNVS LARVIEALQF PGDPEPRVCE HHRNPLSLFC ERDQELICGL CGLLGSHQHH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAAAGGG GAGAGGGCTT CCCTTGCTTT CCTTTAATAA CAAGAATTTT AACAAACAAG 60
TGGGTTCTAC CTTTTTTTTT TTTTTTTTTT AAACATCACC TTCCCTGCCC ACCTCCCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR003613--Ubox_domain
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY
SM00504--Ubox

Gene Ontology

GO:0016235--C:aggresome
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0070201--P:regulation of establishment of protein localization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001406	Ailuropoda melanoleuca	95.07	0.00e+00	951.00
IUUC-Apl-004051	Anas platyrhynchos	63.36	8.00e-178	616.00
IUUC-Ame-010964	Astyanax mexicanus	53.77	4.00e-158	551.00
IUUC-Bta-012642	Bos taurus	90.19	0.00e+00	875.00
IUUC-Cja-019011	Callithrix jacchus	85.62	0.00e+00	797.00
IUUC-Cfa-020270	Canis familiaris	94.05	0.00e+00	946.00
IUUC-Cpo-022458	Cavia porcellus	87.61	0.00e+00	850.00
IUUC-Csa-023478	Chlorocebus sabaeus	89.14	0.00e+00	864.00
IUUC-Dno-028894	Dasypus novemcinctus	87.31	0.00e+00	845.00
IUUC-Dor-030228	Dipodomys ordii	83.01	0.00e+00	718.00
IUUC-Eca-033497	Equus caballus	91.17	0.00e+00	914.00
IUUC-Eeu-034910	Erinaceus europaeus	76.00	4.00e-132	464.00
IUUC-Fca-036164	Felis catus	93.43	0.00e+00	936.00
IUUC-Gga-040573	Gallus gallus	56.12	1.00e-97	350.00
IUUC-Ggo-044471	Gorilla gorilla	89.12	0.00e+00	867.00
IUUC-Hsa-046039	Homo sapiens	89.12	0.00e+00	868.00
IUUC-Itr-048897	Ictidomys tridecemlineatus	87.64	0.00e+00	833.00
IUUC-Kpa-049137	Komagataella pastoris	39.33	8.00e-10	58.20
IUUC-Lch-050638	Latimeria chalumnae	56.03	6.00e-162	563.00
IUUC-Loc-051971	Lepisosteus oculatus	54.56	3.00e-157	548.00
IUUC-Laf-054291	Loxodonta africana	89.98	0.00e+00	865.00
IUUC-Mcc-055708	Macaca mulatta	89.14	0.00e+00	863.00
IUUC-Meu-056670	Macropus eugenii	72.54	1.00e-144	506.00
IUUC-Mla-059039	Melampsora laricipopulina	42.31	7.00e-10	58.50
IUUC-Mga-059415	Meleagris gallopavo	61.64	1.00e-177	615.00
IUUC-Mmr-061410	Microcebus murinus	89.03	0.00e+00	834.00
IUUC-Mmu-064094	Mus musculus	87.08	0.00e+00	875.00
IUUC-Mlu-067974	Myotis lucifugus	88.94	0.00e+00	860.00
IUUC-Nle-069000	Nomascus leucogenys	89.12	0.00e+00	868.00
IUUC-Opr-071216	Ochotona princeps	86.98	4.00e-111	394.00
IUUC-Ocu-074859	Oryctolagus cuniculus	88.82	0.00e+00	855.00
IUUC-Oga-088285	Otolemur garnettii	87.06	0.00e+00	872.00
IUUC-Oar-090161	Ovis aries	81.56	0.00e+00	783.00
IUUC-Ptr-091672	Pan troglodytes	89.12	0.00e+00	868.00
IUUC-Pan-092870	Papio anubis	89.55	0.00e+00	865.00
IUUC-Psi-093742	Pelodiscus sinensis	65.13	0.00e+00	657.00
IUUC-Pab-098034	Pongo abelii	89.32	0.00e+00	871.00
IUUC-Pca-100115	Procavia capensis	82.42	1.00e-69	256.00
IUUC-Pva-103234	Pteropus vampyrus	91.04	0.00e+00	879.00
IUUC-Rno-105163	Rattus norvegicus	86.34	0.00e+00	854.00
IUUC-Sha-106575	Sarcophilus harrisii	63.93	3.00e-163	567.00
IUUC-Ssc-115600	Sus scrofa	90.97	0.00e+00	909.00
IUUC-Tbe-128151	Tupaia belangeri	89.13	6.00e-95	339.00
IUUC-Ttr-128947	Tursiops truncatus	90.55	0.00e+00	871.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence