iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117673

UUCD1 version

UUC-TaR-00216

Ensembl Protein ID

ENSTRUP00000011483.1

UniProt Accession

H2SGF1; H2SGF1_TAKRU

Protein Name

Uncharacterized protein

Gene Name

ubr2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000004807.1	ENSTRUT00000011543.1	ENSTRUP00000011483.1
ENSTRUG00000004807.1	ENSTRUT00000011544.1	ENSTRUP00000011484.1
ENSTRUG00000004807.1	ENSTRUT00000011545.1	ENSTRUP00000011485.1
ENSTRUG00000004807.1	ENSTRUT00000011546.1	ENSTRUP00000011486.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/N-recognin/N-domain	1.00e-36	126.1	234	309
E3 activity/RING/RING	1.40e-08	36.3	1118	1223
E3 activity/N-recognin/UBR-box	1.20e-28	100.7	105	174

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy++LfNDE+H+yeqviy+lqkA+++ qkea  fat++d++GR++v++Gd++ ce+ak++i++n++++++ pL+Vev
   Q: 234  YYCMLFNDEVHTYEQVIYTLQKAVNCSQKEAVSFATTVDRDGRKSVRYGDFQFCEQAKSVIVRNTSRQSK-PLRVEV 309
           9*********************************************************************.****97 PP

E3 activity/RING/RING

   S: 1    CaiCledf...............kd.............................gplvlpCgHvfhadClqkw.............. 29
           C++C+e+                ++                             g ++ +CgH++ha+C+q++              
   Q: 1118 CILCQEEQevrgqgramvlaafvQRstvlsknrqrtlpdperrdplfmhpdlslGIHTASCGHIMHASCWQRYfeavqlkeqrrqqr 1204
           888877665554444444444440033333344444444444444444444444577899*************************** PP
   S: 30   ...pglknssskefrCPlC 45
              + ++n++++ef+CPlC
   Q: 1205 lrgHTSYNVENGEFLCPLC 1223
           ******************* PP

E3 activity/N-recognin/UBR-box

   S: 2    lCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           lCg+vfkvge +y+Cr+C+ d+t+vlC++Cf  +vHk H+y++++sggggfCdCGd+eAw++g++C+k++
   Q: 105  LCGHVFKVGEPTYSCRECAADPTCVLCMQCFLGSVHKTHRYRMTTSGGGGFCDCGDSEAWKKGPYCQKHT 174
           7******************************************************************996 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MAAAESDRDS PSTLSAEFLN FSAKDTSARW QLAADLQQVV YAHLAVYVPR IFCLGPSASS 60
SSREEQREDL ACQLLLLAPL EWLLLGEEPA SGLALLQEKN QPSPLCGHVF KVGEPTYSCR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCCG CAGAGTCGGA CAGAGATTCA CCGTCCACTT TAAGTGCTGA ATTCCTGAAT 60
TTTTCAGCCA AAGACACCTC GGCGGTAAGT GGCTCACCGA ACTATCCTGC TTATCAGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0006342--P:chromatin silencing
GO:0033522--P:histone H2A ubiquitination
GO:0071596--P:ubiquitin-dependent protein catabolic process via the N-end rule pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000949	Aegilops tauschii	26.40	3.00e-20	95.10
IUUC-Aml-001876	Ailuropoda melanoleuca	60.38	0.00e+00	1920.00
IUUC-Atr-002501	Amborella trichopoda	30.55	3.00e-30	128.00
IUUC-Apl-003828	Anas platyrhynchos	67.16	0.00e+00	2276.00
IUUC-Aca-005189	Anolis carolinensis	66.02	0.00e+00	2297.00
IUUC-Aly-005901	Arabidopsis lyrata	32.74	3.00e-25	112.00
IUUC-Ath-007148	Arabidopsis thaliana	31.08	1.00e-24	109.00
IUUC-Ago-007946	Ashbya gossypii	21.29	7.00e-27	117.00
IUUC-Ame-011917	Astyanax mexicanus	75.07	0.00e+00	2515.00
IUUC-Bgr-011999	Blumeria graminis	22.45	9.00e-40	160.00
IUUC-Bta-012768	Bos taurus	64.87	0.00e+00	2219.00
IUUC-Bdi-014635	Brachypodium distachyon	23.37	5.00e-27	117.00
IUUC-Bol-015669	Brassica oleracea	30.47	9.00e-28	120.00
IUUC-Bra-017776	Brassica rapa	30.47	3.00e-28	122.00
IUUC-Cel-018476	Caenorhabditis elegans	32.74	2.00e-83	305.00
IUUC-Cja-019797	Callithrix jacchus	65.20	0.00e+00	1761.00
IUUC-Cfa-020950	Canis familiaris	66.12	0.00e+00	2253.00
IUUC-Cpo-022385	Cavia porcellus	65.40	0.00e+00	2242.00
IUUC-Csa-024082	Chlorocebus sabaeus	65.95	0.00e+00	2260.00
IUUC-Cho-025029	Choloepus hoffmanni	61.05	0.00e+00	1454.00
IUUC-Cin-025148	Ciona intestinalis	36.03	4.00e-138	485.00
IUUC-Csv-026296	Ciona savignyi	29.68	4.00e-19	89.00
IUUC-Cgl-026605	Colletotrichum gloeosporioides	26.16	2.00e-42	169.00
IUUC-Cne-026823	Cryptococcus neoformans	23.20	4.00e-34	141.00
IUUC-Dre-028343	Danio rerio	73.29	0.00e+00	2494.00
IUUC-Dor-030207	Dipodomys ordii	56.49	0.00e+00	1078.00
IUUC-Dse-031531	Dothistroma septosporum	23.17	7.00e-46	180.00
IUUC-Dme-031910	Drosophila melanogaster	33.79	0.00e+00	686.00
IUUC-Ete-033162	Echinops telfairi	64.50	0.00e+00	1052.00
IUUC-Eca-033454	Equus caballus	65.62	0.00e+00	2230.00
IUUC-Eeu-034783	Erinaceus europaeus	53.14	0.00e+00	976.00
IUUC-Fca-036588	Felis catus	66.04	0.00e+00	2239.00
IUUC-Fal-036919	Ficedula albicollis	67.29	0.00e+00	2249.00
IUUC-Fox-037984	Fusarium oxysporum	25.26	3.00e-37	152.00
IUUC-Fso-038463	Fusarium solani	24.73	6.00e-41	164.00
IUUC-Gmo-039698	Gadus morhua	74.46	0.00e+00	1712.00
IUUC-Gga-041123	Gallus gallus	66.85	0.00e+00	2299.00
IUUC-Gac-042622	Gasterosteus aculeatus	82.69	0.00e+00	2738.00
IUUC-Gma-043803	Glycine max	32.03	1.00e-28	123.00
IUUC-Ggo-045583	Gorilla gorilla	65.18	0.00e+00	2237.00
IUUC-Hsa-046343	Homo sapiens	65.43	0.00e+00	2236.00
IUUC-Hvu-047626	Hordeum vulgare	27.78	1.00e-25	112.00
IUUC-Kpa-049088	Komagataella pastoris	21.61	4.00e-35	144.00
IUUC-Lch-049649	Latimeria chalumnae	62.69	0.00e+00	2091.00
IUUC-Lpe-051516	Leersia perrieri	24.18	2.00e-26	115.00
IUUC-Loc-052818	Lepisosteus oculatus	70.59	0.00e+00	2429.00
IUUC-Laf-054142	Loxodonta africana	64.96	0.00e+00	2219.00
IUUC-Mcc-055677	Macaca mulatta	66.00	0.00e+00	2253.00
IUUC-Mpo-057372	Magnaporthe poae	25.36	1.00e-40	163.00
IUUC-Mtr-058538	Medicago truncatula	30.30	8.00e-29	124.00
IUUC-Mla-058963	Melampsora laricipopulina	24.00	8.00e-54	206.00
IUUC-Mga-059698	Meleagris gallopavo	66.99	0.00e+00	2287.00
IUUC-Mvi-060535	Microbotryum violaceum	26.98	3.00e-48	188.00
IUUC-Mmr-060901	Microcebus murinus	64.46	0.00e+00	2201.00
IUUC-Mdo-062014	Monodelphis domestica	66.57	0.00e+00	2278.00
IUUC-Mmu-063699	Mus musculus	64.53	0.00e+00	2195.00
IUUC-Mac-064773	Musa acuminata	31.69	1.00e-27	119.00
IUUC-Mpu-066153	Mustela putorius furo	66.12	0.00e+00	2251.00
IUUC-Mlu-068151	Myotis lucifugus	64.18	0.00e+00	2188.00
IUUC-Nle-069529	Nomascus leucogenys	66.00	0.00e+00	2258.00
IUUC-Opr-071107	Ochotona princeps	58.96	0.00e+00	852.00
IUUC-Ont-072189	Oreochromis niloticus	82.88	0.00e+00	2709.00
IUUC-Oan-072893	Ornithorhynchus anatinus	66.06	0.00e+00	2258.00
IUUC-Ocu-074082	Oryctolagus cuniculus	64.94	0.00e+00	2196.00
IUUC-Obr-076117	Oryza brachyantha	29.20	4.00e-25	111.00
IUUC-Olo-081056	Oryza longistaminata	25.44	1.00e-15	80.10
IUUC-Ome-081738	Oryza meridionalis	24.14	1.00e-13	73.60
IUUC-Opu-083202	Oryza punctata	30.52	5.00e-25	111.00
IUUC-Ola-087460	Oryzias latipes	78.46	0.00e+00	2639.00
IUUC-Oga-088432	Otolemur garnettii	65.19	0.00e+00	2226.00
IUUC-Oar-090206	Ovis aries	65.03	0.00e+00	2230.00
IUUC-Ptr-091180	Pan troglodytes	65.15	0.00e+00	2231.00
IUUC-Pan-092375	Papio anubis	65.89	0.00e+00	2258.00
IUUC-Psi-093049	Pelodiscus sinensis	66.10	0.00e+00	2259.00
IUUC-Pma-094152	Petromyzon marinus	45.44	0.00e+00	627.00
IUUC-Ppa-095715	Physcomitrella patens	30.03	2.00e-22	103.00
IUUC-Pfo-096524	Poecilia formosa	78.66	0.00e+00	2439.00
IUUC-Pab-097989	Pongo abelii	64.47	0.00e+00	2181.00
IUUC-Pop-099496	Populus trichocarpa	29.17	1.00e-16	83.20
IUUC-Pca-100207	Procavia capensis	63.07	0.00e+00	897.00
IUUC-Ppe-101802	Prunus persica	32.41	8.00e-28	120.00
IUUC-Pgr-103372	Puccinia graminis	23.94	5.00e-48	187.00
IUUC-Ptt-103878	Puccinia triticina	24.12	6.00e-47	183.00
IUUC-Rno-105567	Rattus norvegicus	64.49	0.00e+00	2174.00
IUUC-Sce-106272	Saccharomyces cerevisiae	20.65	5.00e-20	94.70
IUUC-Sha-106980	Sarcophilus harrisii	67.59	0.00e+00	2241.00
IUUC-Smo-108719	Selaginella moellendorffii	32.53	6.00e-29	124.00
IUUC-Sit-110716	Setaria italica	28.25	1.00e-26	116.00
IUUC-Sly-111286	Solanum lycopersicum	29.75	1.00e-28	122.00
IUUC-Sar-113332	Sorex araneus	63.27	0.00e+00	1565.00
IUUC-Sbi-114577	Sorghum bicolor	27.40	2.00e-26	115.00
IUUC-Ssc-115525	Sus scrofa	66.86	0.00e+00	1755.00
IUUC-Tgu-116943	Taeniopygia guttata	66.69	0.00e+00	2285.00
IUUC-Tsy-119032	Tarsius syrichta	68.54	0.00e+00	1338.00
IUUC-Tni-119987	Tetraodon nigroviridis	91.61	0.00e+00	2982.00
IUUC-Tca-121077	Theobroma cacao	33.49	1.00e-26	116.00
IUUC-Tre-122137	Trichoderma reesei	25.17	1.00e-59	226.00
IUUC-Tvi-122272	Trichoderma virens	25.72	8.00e-48	187.00
IUUC-Tae-125501	Triticum aestivum	28.52	1.00e-25	112.00
IUUC-Tur-126562	Triticum urartu	31.16	5.00e-25	110.00
IUUC-Tbe-128103	Tupaia belangeri	59.39	0.00e+00	796.00
IUUC-Ttr-128253	Tursiops truncatus	68.62	0.00e+00	1525.00
IUUC-Vda-129778	Verticillium dahliae	24.54	5.00e-41	164.00
IUUC-Vpa-130540	Vicugna pacos	62.82	0.00e+00	2019.00
IUUC-Vvi-131290	Vitis vinifera	31.03	7.00e-29	123.00
IUUC-Xtr-132690	Xenopus tropicalis	65.58	0.00e+00	2259.00
IUUC-Xma-133748	Xiphophorus maculatus	76.47	0.00e+00	2467.00
IUUC-Zma-135553	Zea mays	24.36	2.00e-12	69.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence