iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042430

UUCD1 version

UUC-GaA-00432

Ensembl Protein ID

ENSGACP00000011629.1

UniProt Accession

G3P206; G3P206_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000008789.1	ENSGACT00000011653.1	ENSGACP00000011629.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.30e-120	403.3	4005	4339

Active Site

Position(s)	Description	Evidence
4307	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrll 88
           ++d+k+rl++ f+gEeg+d+gG+ re++  +s+e++np++ lf++s++d+ t+++np+s + np+hl++F+f+Gr+++ka++d+rll
   Q: 4005 PEDMKNRLYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHC-NPNHLSYFKFVGRVVAKAVYDNRLL 4090
           689********************************************************86.99*********************** PP
   S: 89   dlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvk 175
           ++ +++sfyk++lgk++ + d+e+ d  +++ l +++en   d+++lg +ltfs++ +++g +++++Lkp+G+ni Vt+eNk+eYv+
   Q: 4091 ECYFTRSFYKHILGKSVRYTDMESEDYPFFQGLVYLLEN---DVSTLGYELTFSTEVQEFGVCEVRDLKPNGANILVTEENKKEYVH 4174
           *************************************99...********************************************* PP
   S: 176  lvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerk 262
           lv++++++  i++q++af eGf+e+ip++l+s+Fte+elelli+G ++id++dlk++t+y++ y+++s +iqwFw++l++f++ +r+
   Q: 4175 LVCQMKMTGAIRKQLAAFLEGFYEIIPKRLISIFTEQELELLISGLPTIDIDDLKANTEYHK-YQSSSIQIQWFWRALRSFDQADRA 4260
           ************************************************************66.************************ PP
   S: 263  afLqFvTgssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           +fLqFvTg+s++Pl+Gfa+l+     ++f+i++ d+s+drlPs++TCfn+L+LP Y+s+e+l+++Ll+Ai+e+ +gF+l
   Q: 4261 KFLQFVTGTSKVPLQGFAALEgmngIQKFQIHRdDRSTDRLPSAHTCFNQLDLPAYESYEKLRHMLLLAIQECsEGFGL 4339
           *********************99998999999988899***************************************97 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MKVDRSKLKK TPTEAPADCR ILIEKLKACS DEQLLVELQH IKTWNIGKCE LYHWVDLLDR 60
FDGILCDAGQ TVENMSWLLV CDRPDNGQLK ALLLAVLNFT ALLIEYSFSR HLYSSIEHLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGGTTG ACAGAAGCAA GTTAAAGAAA ACTCCTACGG AAGCTGTGAG TATTGCTATG 60
TGGCCATTCT TAGCCTCATT GTGATTTCAT TAGAGTTGGG ACACTATGAC CAAATGTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr

PROSITE

PS50237--HECT
PS50030--UBA
PS50918--WWE

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA
PF02825--WWE

SMART

SM00119--HECTc
SM00165--UBA
SM00678--WWE

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	46.95	9.00e-107	383.00
IUUC-Aml-001684	Ailuropoda melanoleuca	83.09	0.00e+00	3726.00
IUUC-Atr-002582	Amborella trichopoda	49.47	1.00e-126	449.00
IUUC-Apl-003729	Anas platyrhynchos	91.57	0.00e+00	684.00
IUUC-Aca-005263	Anolis carolinensis	81.85	0.00e+00	3698.00
IUUC-Aly-006083	Arabidopsis lyrata	51.77	2.00e-126	449.00
IUUC-Ath-007472	Arabidopsis thaliana	51.77	9.00e-127	449.00
IUUC-Ago-008005	Ashbya gossypii	47.79	2.00e-131	465.00
IUUC-Acl-008254	Aspergillus clavatus	53.43	8.00e-134	473.00
IUUC-Afl-008712	Aspergillus flavus	46.56	3.00e-135	476.00
IUUC-Afu-009022	Aspergillus fumigatus	46.37	2.00e-133	472.00
IUUC-Ani-009412	Aspergillus nidulans	47.33	2.00e-135	478.00
IUUC-Ang-009771	Aspergillus niger	46.37	2.00e-134	475.00
IUUC-Aor-010186	Aspergillus oryzae	45.84	3.00e-125	443.00
IUUC-Ate-010253	Aspergillus terreus	46.65	2.00e-134	475.00
IUUC-Ame-011067	Astyanax mexicanus	89.38	0.00e+00	3979.00
IUUC-Bgr-012043	Blumeria graminis	47.61	3.00e-139	491.00
IUUC-Bta-012813	Bos taurus	83.02	0.00e+00	3755.00
IUUC-Bci-013995	Botrytis cinerea	46.65	2.00e-137	485.00
IUUC-Bdi-014884	Brachypodium distachyon	51.99	2.00e-127	452.00
IUUC-Bol-016533	Brassica oleracea	57.97	6.00e-89	320.00
IUUC-Bra-016637	Brassica rapa	50.78	1.00e-123	439.00
IUUC-Cel-018179	Caenorhabditis elegans	61.72	0.00e+00	649.00
IUUC-Cja-018741	Callithrix jacchus	83.05	0.00e+00	3746.00
IUUC-Cfa-020083	Canis familiaris	82.34	0.00e+00	3711.00
IUUC-Cpo-021923	Cavia porcellus	83.12	0.00e+00	3718.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	48.72	9.00e-119	420.00
IUUC-Csa-023853	Chlorocebus sabaeus	83.22	0.00e+00	3740.00
IUUC-Cho-024718	Choloepus hoffmanni	97.60	0.00e+00	799.00
IUUC-Cin-025627	Ciona intestinalis	41.68	0.00e+00	1893.00
IUUC-Csv-025824	Ciona savignyi	47.74	0.00e+00	1407.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	52.00	4.00e-136	481.00
IUUC-Cne-027095	Cryptococcus neoformans	41.38	1.00e-103	372.00
IUUC-Cme-027267	Cyanidioschyzon merolae	50.00	3.00e-115	410.00
IUUC-Dre-028525	Danio rerio	89.38	0.00e+00	3899.00
IUUC-Dno-029680	Dasypus novemcinctus	82.10	0.00e+00	3685.00
IUUC-Dor-030902	Dipodomys ordii	84.95	0.00e+00	1076.00
IUUC-Dse-031197	Dothistroma septosporum	47.07	1.00e-136	483.00
IUUC-Dme-032122	Drosophila melanogaster	69.29	0.00e+00	790.00
IUUC-Ete-032690	Echinops telfairi	78.96	0.00e+00	1129.00
IUUC-Eca-033915	Equus caballus	82.58	0.00e+00	3693.00
IUUC-Eeu-034963	Erinaceus europaeus	81.97	0.00e+00	2609.00
IUUC-Fca-035824	Felis catus	83.18	0.00e+00	3736.00
IUUC-Fox-037756	Fusarium oxysporum	46.86	1.00e-136	483.00
IUUC-Fso-038464	Fusarium solani	47.71	8.00e-137	483.00
IUUC-Gmo-039073	Gadus morhua	91.04	0.00e+00	6794.00
IUUC-Ggr-039946	Gaeumannomyces graminis	45.99	2.00e-134	475.00
IUUC-Gga-040309	Gallus gallus	97.08	0.00e+00	644.00
IUUC-Gma-044247	Glycine max	52.22	3.00e-126	448.00
IUUC-Ggo-044785	Gorilla gorilla	83.14	0.00e+00	3712.00
IUUC-Hsa-046879	Homo sapiens	83.14	0.00e+00	3715.00
IUUC-Hvu-047697	Hordeum vulgare	51.99	7.00e-128	453.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	88.89	0.00e+00	1366.00
IUUC-Kpa-049228	Komagataella pastoris	48.66	4.00e-139	490.00
IUUC-Lch-050252	Latimeria chalumnae	82.63	0.00e+00	3102.00
IUUC-Lpe-051550	Leersia perrieri	51.15	1.00e-127	452.00
IUUC-Loc-052472	Lepisosteus oculatus	85.66	0.00e+00	3779.00
IUUC-Lma-053159	Leptosphaeria maculans	46.37	2.00e-135	478.00
IUUC-Laf-054154	Loxodonta africana	82.97	0.00e+00	3689.00
IUUC-Mcc-055085	Macaca mulatta	82.22	0.00e+00	3693.00
IUUC-Meu-056727	Macropus eugenii	87.92	0.00e+00	1786.00
IUUC-Mor-057201	Magnaporthe oryzae	47.15	2.00e-135	479.00
IUUC-Mpo-057597	Magnaporthe poae	46.11	5.00e-133	470.00
IUUC-Mtr-058273	Medicago truncatula	52.93	1.00e-127	453.00
IUUC-Mla-058888	Melampsora laricipopulina	49.62	1.00e-116	412.00
IUUC-Mvi-060320	Microbotryum violaceum	49.29	7.00e-122	433.00
IUUC-Mmr-060820	Microcebus murinus	81.16	0.00e+00	3694.00
IUUC-Mdo-062930	Monodelphis domestica	82.08	0.00e+00	3693.00
IUUC-Mmu-063601	Mus musculus	82.87	0.00e+00	3669.00
IUUC-Mac-065557	Musa acuminata	52.09	3.00e-119	424.00
IUUC-Mpu-066653	Mustela putorius furo	81.42	0.00e+00	3605.00
IUUC-Mlu-067418	Myotis lucifugus	83.32	0.00e+00	3794.00
IUUC-Nfi-068278	Neosartorya fischeri	46.56	5.00e-134	474.00
IUUC-Ncr-068813	Neurospora crassa	46.95	1.00e-136	483.00
IUUC-Nle-069418	Nomascus leucogenys	83.13	0.00e+00	3705.00
IUUC-Opr-070187	Ochotona princeps	79.97	0.00e+00	843.00
IUUC-Ont-071300	Oreochromis niloticus	94.22	0.00e+00	4182.00
IUUC-Oan-073046	Ornithorhynchus anatinus	73.74	0.00e+00	4416.00
IUUC-Ocu-074178	Oryctolagus cuniculus	83.01	0.00e+00	3773.00
IUUC-Oba-075757	Oryza barthii	51.15	8.00e-128	453.00
IUUC-Obr-076553	Oryza brachyantha	51.61	1.00e-127	452.00
IUUC-Ogl-077520	Oryza glaberrima	51.15	7.00e-128	453.00
IUUC-Ogu-078278	Oryza glumaepatula	51.15	8.00e-128	453.00
IUUC-Oin-079767	Oryza indica	51.15	9.00e-128	453.00
IUUC-Olo-080380	Oryza longistaminata	50.68	6.00e-126	447.00
IUUC-Ome-081925	Oryza meridionalis	50.68	5.00e-126	447.00
IUUC-Oni-082619	Oryza nivara	51.15	7.00e-128	453.00
IUUC-Opu-083684	Oryza punctata	50.68	3.00e-126	448.00
IUUC-Oru-084501	Oryza rufipogon	51.15	8.00e-128	453.00
IUUC-Osa-086251	Oryza sativa	51.15	2.00e-126	446.00
IUUC-Ola-087437	Oryzias latipes	94.39	0.00e+00	2318.00
IUUC-Olu-087813	Ostreococcus lucimarinus	50.25	1.00e-113	402.00
IUUC-Oga-088903	Otolemur garnettii	83.28	0.00e+00	3728.00
IUUC-Oar-090210	Ovis aries	82.02	0.00e+00	3709.00
IUUC-Ptr-090502	Pan troglodytes	81.56	0.00e+00	2784.00
IUUC-Pan-092368	Papio anubis	81.70	0.00e+00	2818.00
IUUC-Pma-094246	Petromyzon marinus	74.02	0.00e+00	1244.00
IUUC-Pno-094871	Phaeosphaeria nodorum	51.58	2.00e-133	472.00
IUUC-Ppa-095657	Physcomitrella patens	51.36	1.00e-125	446.00
IUUC-Pfo-096232	Poecilia formosa	91.15	0.00e+00	4125.00
IUUC-Pab-098583	Pongo abelii	83.18	0.00e+00	3716.00
IUUC-Pop-099613	Populus trichocarpa	53.40	6.00e-129	456.00
IUUC-Pca-100310	Procavia capensis	74.28	0.00e+00	1467.00
IUUC-Ppe-102109	Prunus persica	52.69	2.00e-127	452.00
IUUC-Pva-102116	Pteropus vampyrus	82.93	0.00e+00	3777.00
IUUC-Pgr-103465	Puccinia graminis	44.34	5.00e-128	454.00
IUUC-Ptt-103813	Puccinia triticina	42.23	2.00e-115	412.00
IUUC-Pte-104018	Pyrenophora teres	51.23	3.00e-132	468.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	51.24	7.00e-132	467.00
IUUC-Rno-105889	Rattus norvegicus	76.62	0.00e+00	3313.00
IUUC-Sce-106449	Saccharomyces cerevisiae	45.49	5.00e-127	450.00
IUUC-Sha-106961	Sarcophilus harrisii	81.35	0.00e+00	3665.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	45.79	5.00e-128	454.00
IUUC-Spo-108024	Schizosaccharomyces pombe	46.64	6.00e-130	460.00
IUUC-Smo-109428	Selaginella moellendorffii	50.88	4.00e-130	461.00
IUUC-Sit-110598	Setaria italica	52.46	7.00e-128	453.00
IUUC-Sly-111285	Solanum lycopersicum	51.89	1.00e-128	456.00
IUUC-Stu-112582	Solanum tuberosum	32.68	2.00e-56	214.00
IUUC-Sar-113291	Sorex araneus	76.53	0.00e+00	2259.00
IUUC-Sbi-114042	Sorghum bicolor	51.99	3.00e-127	451.00
IUUC-Sre-114958	Sporisorium reilianum	56.03	4.00e-138	484.00
IUUC-Ssc-115754	Sus scrofa	83.24	0.00e+00	3723.00
IUUC-Tru-118570	Takifugu rubripes	94.15	0.00e+00	4195.00
IUUC-Tsy-119159	Tarsius syrichta	88.57	0.00e+00	1748.00
IUUC-Tni-120836	Tetraodon nigroviridis	87.77	0.00e+00	5029.00
IUUC-Tca-121479	Theobroma cacao	51.76	1.00e-125	446.00
IUUC-Tre-121909	Trichoderma reesei	53.65	9.00e-134	473.00
IUUC-Tvi-122370	Trichoderma virens	46.67	2.00e-133	472.00
IUUC-Tae-125214	Triticum aestivum	51.04	8.00e-126	446.00
IUUC-Tme-127172	Tuber melanosporum	47.23	1.00e-137	486.00
IUUC-Tbe-127506	Tupaia belangeri	72.86	0.00e+00	1135.00
IUUC-Ttr-129253	Tursiops truncatus	72.11	0.00e+00	1728.00
IUUC-Uma-129355	Ustilago maydis	49.24	8.00e-139	487.00
IUUC-Vda-129886	Verticillium dahliae	47.25	1.00e-138	489.00
IUUC-Vpa-130708	Vicugna pacos	81.65	0.00e+00	3261.00
IUUC-Vvi-131170	Vitis vinifera	51.22	2.00e-127	451.00
IUUC-Xtr-132123	Xenopus tropicalis	75.99	0.00e+00	5762.00
IUUC-Xma-133869	Xiphophorus maculatus	91.27	0.00e+00	4153.00
IUUC-Yli-134657	Yarrowia lipolytica	46.07	9.00e-130	459.00
IUUC-Zma-135570	Zea mays	51.99	1.00e-127	452.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence