iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089410

Ensembl Protein ID

ENSOARP00000003628.1

UniProt Accession

W5NZN0; W5NZN0_SHEEP

Genbank Protein ID

ENSOARP00000003628

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01019187

Gene Name

USP36

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000003393.1	ENSOART00000003694.1	ENSOARP00000003628.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.50e-80	270.4	123	420

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           Gl+NlgNtC++NS++QcL+ +p+l+++ll+ ++++ ++     + + ++l+ +q+ + +   ++ +a++p ++++ l+k+a++f+  +q
   Q: 123  GLHNLGNTCFLNSTVQCLTYTPPLANYLLSkEHTRGCH-----QGSFCMLCVMQNHIIQAFANSGNAIKPVSFIRDLRKIARHFRFGNQ 206
           9*****************************44444454.....457899999999999999**************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da+Efl++ +d++++++                  ls  a+ + +++ ++l++++F+g l+s++kc  c++vs +++p ld+ l++++
   Q: 207  EDAHEFLRYTIDAMQKAC------------------LSGCAKLDRQTQATTLVHQIFGGYLRSRVKCSMCKSVSDTYDPYLDVALEIRQ 277
           ******************..................55566778999****************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
                  ++  +Le f+k++ l gen+y c kck+k+ a+k++++++ ++vL+l LkRf    ++ s  ki+k v +p+ L+++p++++
   Q: 278  AA-----NIVRALELFVKPDVLSGENAYMCAKCKRKVPASKRFTIHRTSNVLTLSLKRF----ANFSGGKITKDVGYPEFLNIRPYMSQ 357
           **.....9***************************************************....668899******************** PP
   S: 268  peekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfY 335
           ++ +   ++ Y L+av+vHsG s++ GHY++yvk ++g+W++++Ds+V++++ + vl+   ++aYvlfY
   Q: 358  SSGE---PVMYGLYAVLVHSGySCHAGHYYCYVKASNGQWYQMNDSSVHASNIKVVLN---QQAYVLFY 420
           5544...9**************************************************...******** PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MPIVDKLKEA LKPGRRDSAD DGELGKLLAA SAKKVLLQKL EFEPASKSFS YQLESLKSKY 60
VLLNPRTEGA GCHRSGDEPP ARRQGSEHAY ESCSDGVPAP QKVLFPVERL SLRWGRVYRV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTCTGATGC CCCTTCCGGA AAACACGCTT GTAGCTCTGA TCATTTAACG GGCCCAAAGC 60
TGGGAAGCAC GTGATTTTGA GGGCCTAGCA CCCTGCCTAC CCAGTCCGGC CAAGCACCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016607--C:nuclear speck
GO:0005730--C:nucleolus
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0016579--P:protein deubiquitination
GO:1903146--P:regulation of mitophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002092	Ailuropoda melanoleuca	71.00	0.00e+00	1305.00
IUUC-Atr-003102	Amborella trichopoda	46.35	3.00e-85	310.00
IUUC-Aca-005360	Anolis carolinensis	62.40	0.00e+00	865.00
IUUC-Aly-006389	Arabidopsis lyrata	38.25	4.00e-76	279.00
IUUC-Bta-013047	Bos taurus	91.83	0.00e+00	1719.00
IUUC-Bdi-014036	Brachypodium distachyon	45.71	7.00e-85	308.00
IUUC-Bol-015996	Brassica oleracea	45.05	2.00e-81	297.00
IUUC-Bra-016634	Brassica rapa	45.37	4.00e-82	299.00
IUUC-Cja-019203	Callithrix jacchus	68.14	0.00e+00	1194.00
IUUC-Cfa-020586	Canis familiaris	71.49	0.00e+00	1358.00
IUUC-Cpo-021804	Cavia porcellus	63.22	0.00e+00	1137.00
IUUC-Cre-022988	Chlamydomonas reinhardtii	47.51	1.00e-52	199.00
IUUC-Csa-023137	Chlorocebus sabaeus	69.94	0.00e+00	1302.00
IUUC-Cin-025230	Ciona intestinalis	52.57	1.00e-97	349.00
IUUC-Cme-027339	Cyanidioschyzon merolae	35.81	2.00e-59	223.00
IUUC-Dre-028587	Danio rerio	74.25	0.00e+00	802.00
IUUC-Dno-029149	Dasypus novemcinctus	65.09	0.00e+00	1174.00
IUUC-Dor-030836	Dipodomys ordii	62.81	0.00e+00	877.00
IUUC-Dme-032119	Drosophila melanogaster	33.40	3.00e-70	260.00
IUUC-Ete-032567	Echinops telfairi	64.23	0.00e+00	782.00
IUUC-Eca-033600	Equus caballus	74.25	0.00e+00	1380.00
IUUC-Eeu-035206	Erinaceus europaeus	55.31	2.00e-129	457.00
IUUC-Fca-036392	Felis catus	60.66	0.00e+00	630.00
IUUC-Gmo-039033	Gadus morhua	73.82	0.00e+00	794.00
IUUC-Gga-040664	Gallus gallus	77.60	0.00e+00	743.00
IUUC-Gac-042176	Gasterosteus aculeatus	63.64	0.00e+00	802.00
IUUC-Gma-044075	Glycine max	45.58	4.00e-85	309.00
IUUC-Ggo-045437	Gorilla gorilla	69.46	0.00e+00	1259.00
IUUC-Hsa-046863	Homo sapiens	69.38	0.00e+00	1249.00
IUUC-Itr-048655	Ictidomys tridecemlineatus	66.52	0.00e+00	993.00
IUUC-Lch-050120	Latimeria chalumnae	61.93	0.00e+00	724.00
IUUC-Lpe-051574	Leersia perrieri	40.26	1.00e-78	288.00
IUUC-Loc-052796	Lepisosteus oculatus	67.83	0.00e+00	771.00
IUUC-Laf-054243	Loxodonta africana	65.03	0.00e+00	1200.00
IUUC-Mcc-055762	Macaca mulatta	69.70	0.00e+00	1275.00
IUUC-Meu-056697	Macropus eugenii	60.18	0.00e+00	1161.00
IUUC-Mtr-058537	Medicago truncatula	49.02	2.00e-84	307.00
IUUC-Mla-059049	Melampsora laricipopulina	42.41	5.00e-59	222.00
IUUC-Mga-059359	Meleagris gallopavo	79.94	2.00e-154	540.00
IUUC-Mmr-060966	Microcebus murinus	67.86	0.00e+00	1218.00
IUUC-Mdo-062733	Monodelphis domestica	67.64	0.00e+00	998.00
IUUC-Mmu-064331	Mus musculus	64.08	0.00e+00	1161.00
IUUC-Mac-065039	Musa acuminata	40.82	3.00e-88	320.00
IUUC-Mpu-065759	Mustela putorius furo	70.76	0.00e+00	1259.00
IUUC-Mlu-067371	Myotis lucifugus	67.08	0.00e+00	1202.00
IUUC-Nle-070087	Nomascus leucogenys	68.67	0.00e+00	1234.00
IUUC-Opr-070729	Ochotona princeps	62.47	0.00e+00	914.00
IUUC-Ont-071346	Oreochromis niloticus	77.69	0.00e+00	798.00
IUUC-Oan-072931	Ornithorhynchus anatinus	75.89	0.00e+00	840.00
IUUC-Ocu-074823	Oryctolagus cuniculus	67.44	0.00e+00	867.00
IUUC-Oba-075866	Oryza barthii	45.08	6.00e-84	305.00
IUUC-Obr-076408	Oryza brachyantha	43.24	1.00e-83	304.00
IUUC-Ogl-077239	Oryza glaberrima	45.08	6.00e-84	305.00
IUUC-Ogu-078064	Oryza glumaepatula	45.08	4.00e-84	306.00
IUUC-Oin-079157	Oryza indica	45.08	5.00e-84	305.00
IUUC-Olo-080231	Oryza longistaminata	43.49	6.00e-76	279.00
IUUC-Ome-081746	Oryza meridionalis	45.57	1.00e-82	301.00
IUUC-Oni-082339	Oryza nivara	45.08	5.00e-84	306.00
IUUC-Opu-083194	Oryza punctata	45.08	2.00e-83	305.00
IUUC-Oru-085083	Oryza rufipogon	45.08	4.00e-84	306.00
IUUC-Osa-085395	Oryza sativa	45.71	3.00e-84	306.00
IUUC-Ola-087255	Oryzias latipes	71.08	0.00e+00	814.00
IUUC-Olu-087773	Ostreococcus lucimarinus	45.54	1.00e-71	263.00
IUUC-Oga-088818	Otolemur garnettii	66.00	0.00e+00	1018.00
IUUC-Ptr-090680	Pan troglodytes	68.82	0.00e+00	1093.00
IUUC-Pan-092482	Papio anubis	69.65	0.00e+00	1297.00
IUUC-Ppa-095853	Physcomitrella patens	47.28	8.00e-91	328.00
IUUC-Pfo-096807	Poecilia formosa	71.83	0.00e+00	824.00
IUUC-Pab-098724	Pongo abelii	69.58	0.00e+00	1292.00
IUUC-Pop-099693	Populus trichocarpa	46.50	5.00e-83	302.00
IUUC-Pca-100117	Procavia capensis	75.66	1.00e-151	530.00
IUUC-Pva-102883	Pteropus vampyrus	61.14	0.00e+00	1004.00
IUUC-Pgr-103270	Puccinia graminis	44.97	3.00e-67	249.00
IUUC-Ptt-103887	Puccinia triticina	43.38	9.00e-67	248.00
IUUC-Rno-105340	Rattus norvegicus	65.94	0.00e+00	977.00
IUUC-Sha-107019	Sarcophilus harrisii	59.31	0.00e+00	1141.00
IUUC-Sja-107805	Schizosaccharomyces japonicus	42.49	2.00e-74	272.00
IUUC-Spo-108119	Schizosaccharomyces pombe	43.06	9.00e-81	293.00
IUUC-Sit-110536	Setaria italica	45.71	2.00e-79	290.00
IUUC-Sly-111722	Solanum lycopersicum	39.35	3.00e-78	286.00
IUUC-Stu-112912	Solanum tuberosum	39.66	1.00e-78	288.00
IUUC-Sbi-114477	Sorghum bicolor	45.71	4.00e-86	313.00
IUUC-Sre-114924	Sporisorium reilianum	40.90	3.00e-66	246.00
IUUC-Ssc-116022	Sus scrofa	89.50	0.00e+00	907.00
IUUC-Tgu-116976	Taeniopygia guttata	70.66	1.00e-156	545.00
IUUC-Tru-118391	Takifugu rubripes	63.91	0.00e+00	818.00
IUUC-Tsy-119253	Tarsius syrichta	51.73	0.00e+00	696.00
IUUC-Tni-120064	Tetraodon nigroviridis	77.89	0.00e+00	795.00
IUUC-Tae-125259	Triticum aestivum	47.47	1.00e-87	318.00
IUUC-Tur-126014	Triticum urartu	46.56	4.00e-83	303.00
IUUC-Tbe-127377	Tupaia belangeri	57.16	0.00e+00	715.00
IUUC-Ttr-129259	Tursiops truncatus	86.97	0.00e+00	794.00
IUUC-Uma-129416	Ustilago maydis	43.64	1.00e-68	254.00
IUUC-Vpa-130568	Vicugna pacos	68.38	8.00e-45	175.00
IUUC-Xtr-132944	Xenopus tropicalis	76.72	0.00e+00	672.00
IUUC-Xma-133735	Xiphophorus maculatus	72.44	0.00e+00	828.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence