iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090475

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03073859

Gene Name

BTRC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000002869.5	ENSPTRT00000064287.2	ENSPTRP00000055839.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-59	194.9	443	478
UBD/Beta-Prp	4.40e-69	232.9	357	521

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvll 36
           gH++ v+c++f d +++vsG++Dg+ikvWDl    ++
   Q: 443  GHEELVRCIRF-DnKRIVSGAYDGKIKVWDLVAALDP 478
           8**********.44****************9876665 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleet 132
           l r l gh a+v+ v+f+++  ++v++s Drtikvw+ st++ v+tl+gh++ + +l++      +vsGs+d+tir+wd+e g cl+ +
   Q: 357  LRRVLVGHRAAVNVVDFDDK--YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLR-V 440
           445579*************9..8**************************************..************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           l+gh+++v+c++++   + +vsG++D+++++Wdl         +   +lrtl + h ++v  l+fd+  +++vs s+d t+ +wd+
   Q: 441  LEGHEELVRCIRFDN--KRIVSGAYDGKIKVWDLvaaldprapAGTLCLRTLVE-HSGRVFRLQFDE--FQIVSSSHDDTILIWDF 521
           **************9..*************************877889****98.************..99**************7 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MDPAEAVLQE KALKFMCSMP RSLWLGCSSL ADSMPSLRCL YNPGTGALTA FQNSSEREDC 60
NNGEPPRKII PEKNSLRQTY NSCARLCLNQ ETVCLGSTAM KTENCVAKTK LANGTSSMIV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTGGCCTC GGCGATTATG GACCCGGCCG AGGCGGTGCT GCAAGAGAAG GCACTCAAGT 60
TTATGGTGAG GAGACGGTGG AGGCCGGGGA ACGGTGGAGG CGCTGGCGTT GGCGGCGTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0071407--P:cellular response to organic cyclic compound
GO:0033598--P:mammary gland epithelial cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0042753--P:positive regulation of circadian rhythm
GO:0045862--P:positive regulation of proteolysis
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006470--P:protein dephosphorylation
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:0060828--P:regulation of canonical Wnt signaling pathway
GO:0051726--P:regulation of cell cycle
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061136--P:regulation of proteasomal protein catabolic process
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001961	Ailuropoda melanoleuca	79.37	0.00e+00	937.00
IUUC-Aca-004410	Anolis carolinensis	76.59	0.00e+00	933.00
IUUC-Acl-008355	Aspergillus clavatus	29.66	1.00e-50	194.00
IUUC-Afl-008678	Aspergillus flavus	34.42	8.00e-44	172.00
IUUC-Afu-008790	Aspergillus fumigatus	30.39	1.00e-48	187.00
IUUC-Ani-009324	Aspergillus nidulans	29.84	2.00e-48	187.00
IUUC-Ang-009766	Aspergillus niger	31.11	2.00e-52	200.00
IUUC-Aor-009916	Aspergillus oryzae	28.15	2.00e-46	181.00
IUUC-Ate-010492	Aspergillus terreus	30.18	2.00e-50	193.00
IUUC-Bgr-012194	Blumeria graminis	32.12	4.00e-52	199.00
IUUC-Cja-019121	Callithrix jacchus	84.31	0.00e+00	964.00
IUUC-Cfa-020553	Canis familiaris	79.54	0.00e+00	937.00
IUUC-Csa-023688	Chlorocebus sabaeus	79.70	0.00e+00	939.00
IUUC-Cgl-026429	Colletotrichum gloeosporioides	33.41	2.00e-59	223.00
IUUC-Dse-031287	Dothistroma septosporum	29.58	5.00e-53	202.00
IUUC-Eeu-034760	Erinaceus europaeus	81.79	2.00e-170	592.00
IUUC-Fca-035427	Felis catus	84.48	0.00e+00	967.00
IUUC-Ggr-039974	Gaeumannomyces graminis	32.12	4.00e-55	209.00
IUUC-Gga-041087	Gallus gallus	78.03	0.00e+00	949.00
IUUC-Hsa-045962	Homo sapiens	79.70	0.00e+00	939.00
IUUC-Lma-053289	Leptosphaeria maculans	38.43	9.00e-48	185.00
IUUC-Mor-057283	Magnaporthe oryzae	33.11	9.00e-58	218.00
IUUC-Mpo-057540	Magnaporthe poae	32.35	1.00e-55	211.00
IUUC-Mla-058989	Melampsora laricipopulina	40.88	4.00e-61	227.00
IUUC-Mmr-060969	Microcebus murinus	79.54	0.00e+00	937.00
IUUC-Mmu-064096	Mus musculus	78.88	0.00e+00	930.00
IUUC-Nfi-068263	Neosartorya fischeri	29.84	7.00e-50	192.00
IUUC-Ncr-068639	Neurospora crassa	34.82	3.00e-45	177.00
IUUC-Nle-069548	Nomascus leucogenys	79.70	0.00e+00	939.00
IUUC-Ocu-074246	Oryctolagus cuniculus	79.54	0.00e+00	937.00
IUUC-Pan-092826	Papio anubis	79.70	0.00e+00	939.00
IUUC-Pab-097680	Pongo abelii	79.21	0.00e+00	933.00
IUUC-Pca-100843	Procavia capensis	76.45	0.00e+00	896.00
IUUC-Pgr-103331	Puccinia graminis	37.69	4.00e-52	198.00
IUUC-Pte-104392	Pyrenophora teres	37.37	1.00e-47	184.00
IUUC-Pyt-104678	Pyrenophora triticirepentis	37.72	6.00e-48	186.00
IUUC-Sar-113471	Sorex araneus	67.95	0.00e+00	780.00
IUUC-Sre-114916	Sporisorium reilianum	34.08	9.00e-46	179.00
IUUC-Tre-122207	Trichoderma reesei	33.02	1.00e-54	207.00
IUUC-Tvi-122344	Trichoderma virens	34.75	2.00e-55	210.00
IUUC-Tme-127141	Tuber melanosporum	33.90	2.00e-63	236.00
IUUC-Ttr-128946	Tursiops truncatus	79.37	0.00e+00	937.00
IUUC-Uma-129491	Ustilago maydis	33.97	6.00e-47	182.00
IUUC-Vda-129941	Verticillium dahliae	32.49	7.00e-56	212.00
IUUC-Vpa-130709	Vicugna pacos	77.56	0.00e+00	903.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence