iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040540

UUCD1 version

UUC-GaG-00732

Ensembl Protein ID

ENSGALP00000060527.1

UniProt Accession

P63247; A5HUK6; P25388; P99049; Q5EVY1; RACK1_CHICK

Genbank Protein ID

AAA50559.1; AAS49613.1; AAW82329.1; BAF62990.1

Protein Name

Receptor of activated protein C kinase 1; Guanine nucleotide-binding protein subunit beta-like protein 12.3; Receptor for activated C kinase; Receptor of activated protein kinase C 1

Genbank Nucleotide ID

M24193; AY393848; AY694127; AB268588

Gene Name

GNB2L1; RACK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000000122.5	ENSGALT00000089517.1	ENSGALP00000060527.1
ENSGALG00000000122.5	ENSGALT00000088792.1	ENSGALP00000060007.1
ENSGALG00000000122.5	ENSGALT00000087483.1	ENSGALP00000058833.1
ENSGALG00000000122.5	ENSGALT00000073944.1	ENSGALP00000051984.1
ENSGALG00000000122.5	ENSGALT00000000171.4	ENSGALP00000000170.4
ENSGALG00000000122.5	ENSGALT00000089345.1	ENSGALP00000058988.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-44	147.8	103	133
UBD/Beta-Prp	2.10e-54	185.1	10	160

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHt +v ++af sd + +vsGs+D+tik+W+
   Q: 103  GHTKDVLSVAFsSDnRQIVSGSRDKTIKLWN 133
           8***********88899*************9 PP

UBD/Beta-Prp

   S: 89   tlkghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkll 172
           tlkgh+  v+ ++  p+  d ++s+s+d+ti +w+l  ++  +      l+gh+++v+ vv+++dg+   sGs D+t+rlWdl tg+  
   Q: 10   TLKGHNGWVTQIATTPQFpDMILSASRDKTIIMWKLTRDETNYGipqrALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTT 98
           78999999999999998889999999999999999876666555666899999999999999999999999999999999999999999 PP
   S: 173  rtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng..htdnvksvrfspnd 234
           r++ g ht++v s++f+s+ +++vsgs+d+t+klw+   g c +t+++  h+++v++vrfspn+
   Q: 99   RRFVG-HTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT-LGVCKYTVQDesHSEWVSCVRFSPNS 160
           99998.9999999999999999999999999999998.67788887766699999999999887 PP

Organism

Gallus gallus

Functional Description
(View)

Involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes (By similarity).

Protein Sequence
(Fasta)

MTEQMTLRGT LKGHNGWVTQ IATTPQFPDM ILSASRDKTI IMWKLTRDET NYGIPQRALR 60
GHSHFVSDVV ISSDGQFALS GSWDGTLRLW DLTTGTTTRR FVGHTKDVLS VAFSSDNRQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTTTCTCT TTCCGCGCTG GCGGCCATCG CGGGCGGTAG GACCGGACCG GGCCGGGCCC 60
TTTATTGAAT CCGCCGCCAT CCCTCCGCCC CGCCGCCGCC ATGACGGAGC AGATGACCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-1003--Cell membrane
KW-0966--Cell projection
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0472--Membrane
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0687--Ribonucleoprotein
KW-0689--Ribosomal protein
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0030425--C:dendrite
GO:0043025--C:neuronal cell body
GO:0005634--C:nucleus
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0030178--P:negative regulation of Wnt signaling pathway
GO:2000543--P:positive regulation of gastrulation
GO:0051302--P:regulation of cell division
GO:2000114--P:regulation of establishment of cell polarity
GO:0032880--P:regulation of protein localization
GO:0007165--P:signal transduction

KEGG

gga:417044

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000395	Aegilops tauschii	64.44	6.00e-103	366.00
IUUC-Aml-001935	Ailuropoda melanoleuca	100.00	0.00e+00	653.00
IUUC-Atr-002694	Amborella trichopoda	67.73	5.00e-125	440.00
IUUC-Apl-003918	Anas platyrhynchos	100.00	1.00e-166	577.00
IUUC-Aca-004869	Anolis carolinensis	100.00	0.00e+00	653.00
IUUC-Aly-005671	Arabidopsis lyrata	65.43	6.00e-125	439.00
IUUC-Ath-007105	Arabidopsis thaliana	66.25	3.00e-125	441.00
IUUC-Ago-007720	Ashbya gossypii	56.23	1.00e-102	365.00
IUUC-Acl-008156	Aspergillus clavatus	72.44	2.00e-138	484.00
IUUC-Afl-008684	Aspergillus flavus	71.47	3.00e-137	480.00
IUUC-Afu-008867	Aspergillus fumigatus	73.40	1.00e-139	489.00
IUUC-Ani-009221	Aspergillus nidulans	72.44	2.00e-138	484.00
IUUC-Ang-009843	Aspergillus niger	71.47	1.00e-136	478.00
IUUC-Aor-010193	Aspergillus oryzae	71.47	3.00e-137	480.00
IUUC-Ate-010420	Aspergillus terreus	72.44	1.00e-124	438.00
IUUC-Ame-010884	Astyanax mexicanus	96.53	0.00e+00	640.00
IUUC-Bgr-012064	Blumeria graminis	70.19	6.00e-135	473.00
IUUC-Bta-013357	Bos taurus	100.00	0.00e+00	653.00
IUUC-Bci-013862	Botrytis cinerea	71.15	2.00e-137	481.00
IUUC-Bdi-014690	Brachypodium distachyon	62.39	5.00e-114	403.00
IUUC-Bol-016231	Brassica oleracea	66.56	8.00e-127	446.00
IUUC-Bra-016879	Brassica rapa	66.15	2.00e-125	441.00
IUUC-Cel-018335	Caenorhabditis elegans	69.06	3.00e-123	434.00
IUUC-Cja-019914	Callithrix jacchus	100.00	0.00e+00	653.00
IUUC-Cfa-020755	Canis familiaris	100.00	0.00e+00	653.00
IUUC-Cpo-022377	Cavia porcellus	100.00	0.00e+00	654.00
IUUC-Cre-022909	Chlamydomonas reinhardtii	74.60	4.00e-137	480.00
IUUC-Csa-023025	Chlorocebus sabaeus	100.00	0.00e+00	652.00
IUUC-Cin-025647	Ciona intestinalis	77.07	2.00e-146	511.00
IUUC-Csv-026027	Ciona savignyi	76.75	2.00e-144	504.00
IUUC-Cgl-026718	Colletotrichum gloeosporioides	74.91	4.00e-129	453.00
IUUC-Cne-026930	Cryptococcus neoformans	71.15	8.00e-137	479.00
IUUC-Cme-027251	Cyanidioschyzon merolae	63.46	6.00e-122	429.00
IUUC-Dre-028669	Danio rerio	95.58	0.00e+00	636.00
IUUC-Dno-029470	Dasypus novemcinctus	84.54	4.00e-149	520.00
IUUC-Dor-031098	Dipodomys ordii	89.91	2.00e-149	521.00
IUUC-Dse-031255	Dothistroma septosporum	71.15	7.00e-137	479.00
IUUC-Dme-032118	Drosophila melanogaster	77.14	1.00e-147	515.00
IUUC-Ete-033182	Echinops telfairi	83.41	1.00e-105	375.00
IUUC-Eca-033296	Equus caballus	100.00	2.00e-87	313.00
IUUC-Eeu-034771	Erinaceus europaeus	94.64	1.00e-176	611.00
IUUC-Fca-036315	Felis catus	100.00	0.00e+00	653.00
IUUC-Fal-036990	Ficedula albicollis	97.22	3.00e-103	367.00
IUUC-Fox-037702	Fusarium oxysporum	72.44	2.00e-139	488.00
IUUC-Fso-038384	Fusarium solani	73.08	9.00e-140	489.00
IUUC-Gmo-039630	Gadus morhua	94.16	1.00e-176	611.00
IUUC-Ggr-039985	Gaeumannomyces graminis	72.76	1.00e-139	488.00
IUUC-Gac-041316	Gasterosteus aculeatus	91.32	4.00e-174	603.00
IUUC-Gma-042872	Glycine max	66.46	1.00e-125	442.00
IUUC-Ggo-045253	Gorilla gorilla	100.00	0.00e+00	653.00
IUUC-Hsa-046809	Homo sapiens	100.00	0.00e+00	653.00
IUUC-Hvu-047683	Hordeum vulgare	63.22	1.00e-115	409.00
IUUC-Itr-048025	Ictidomys tridecemlineatus	100.00	0.00e+00	653.00
IUUC-Kpa-049214	Komagataella pastoris	58.06	8.00e-100	356.00
IUUC-Lch-049634	Latimeria chalumnae	94.32	0.00e+00	628.00
IUUC-Lpe-050762	Leersia perrieri	62.88	1.00e-114	405.00
IUUC-Loc-052163	Lepisosteus oculatus	97.16	0.00e+00	644.00
IUUC-Lma-053113	Leptosphaeria maculans	72.76	3.00e-139	487.00
IUUC-Laf-054422	Loxodonta africana	100.00	0.00e+00	653.00
IUUC-Mcc-055348	Macaca mulatta	100.00	0.00e+00	652.00
IUUC-Meu-056543	Macropus eugenii	100.00	0.00e+00	653.00
IUUC-Mor-057107	Magnaporthe oryzae	72.76	2.00e-140	491.00
IUUC-Mpo-057487	Magnaporthe poae	73.08	3.00e-140	490.00
IUUC-Mtr-058808	Medicago truncatula	66.77	3.00e-126	444.00
IUUC-Mla-058909	Melampsora laricipopulina	73.16	3.00e-139	487.00
IUUC-Mga-059387	Meleagris gallopavo	100.00	0.00e+00	653.00
IUUC-Mvi-060392	Microbotryum violaceum	69.23	3.00e-134	470.00
IUUC-Mmr-061141	Microcebus murinus	89.27	4.00e-139	486.00
IUUC-Mdo-062932	Monodelphis domestica	100.00	0.00e+00	653.00
IUUC-Mmu-064132	Mus musculus	100.00	0.00e+00	653.00
IUUC-Mac-064447	Musa acuminata	61.11	5.00e-109	387.00
IUUC-Mpu-066721	Mustela putorius furo	99.05	0.00e+00	641.00
IUUC-Mlu-068221	Myotis lucifugus	99.37	7.00e-177	612.00
IUUC-Nfi-068344	Neosartorya fischeri	73.40	9.00e-140	489.00
IUUC-Ncr-068722	Neurospora crassa	71.47	2.00e-137	481.00
IUUC-Nle-069865	Nomascus leucogenys	100.00	0.00e+00	653.00
IUUC-Opr-071100	Ochotona princeps	84.86	5.00e-152	530.00
IUUC-Ont-072287	Oreochromis niloticus	94.32	0.00e+00	631.00
IUUC-Oan-072788	Ornithorhynchus anatinus	100.00	0.00e+00	653.00
IUUC-Ocu-073844	Oryctolagus cuniculus	97.48	0.00e+00	630.00
IUUC-Oba-075981	Oryza barthii	59.94	4.00e-103	367.00
IUUC-Obr-076099	Oryza brachyantha	61.47	2.00e-113	401.00
IUUC-Ogl-077804	Oryza glaberrima	62.69	1.00e-115	408.00
IUUC-Ogu-078035	Oryza glumaepatula	63.38	7.00e-115	406.00
IUUC-Oin-079327	Oryza indica	63.38	7.00e-115	406.00
IUUC-Olo-081084	Oryza longistaminata	63.38	7.00e-115	406.00
IUUC-Ome-081366	Oryza meridionalis	63.00	7.00e-116	409.00
IUUC-Oni-082682	Oryza nivara	63.00	7.00e-116	409.00
IUUC-Opu-084010	Oryza punctata	62.69	5.00e-116	410.00
IUUC-Oru-084358	Oryza rufipogon	63.00	7.00e-116	409.00
IUUC-Osa-085296	Oryza sativa	63.00	7.00e-116	409.00
IUUC-Ola-086400	Oryzias latipes	94.01	0.00e+00	630.00
IUUC-Olu-087817	Ostreococcus lucimarinus	75.79	3.00e-142	497.00
IUUC-Oga-088811	Otolemur garnettii	100.00	0.00e+00	653.00
IUUC-Oar-089962	Ovis aries	100.00	0.00e+00	653.00
IUUC-Ptr-091340	Pan troglodytes	100.00	0.00e+00	653.00
IUUC-Pan-091946	Papio anubis	100.00	0.00e+00	652.00
IUUC-Pma-094535	Petromyzon marinus	94.01	0.00e+00	626.00
IUUC-Pno-095100	Phaeosphaeria nodorum	75.00	6.00e-97	346.00
IUUC-Ppa-095588	Physcomitrella patens	75.08	1.00e-139	489.00
IUUC-Pfo-097311	Poecilia formosa	94.01	0.00e+00	629.00
IUUC-Pab-097863	Pongo abelii	100.00	0.00e+00	653.00
IUUC-Pop-099345	Populus trichocarpa	67.80	8.00e-129	452.00
IUUC-Pca-100594	Procavia capensis	99.05	0.00e+00	647.00
IUUC-Ppe-101743	Prunus persica	65.12	3.00e-123	434.00
IUUC-Pva-102746	Pteropus vampyrus	83.91	3.00e-150	524.00
IUUC-Pgr-103375	Puccinia graminis	57.51	4.00e-97	347.00
IUUC-Ptt-103839	Puccinia triticina	73.16	8.00e-138	482.00
IUUC-Pte-104026	Pyrenophora teres	72.76	3.00e-139	487.00
IUUC-Pyt-104584	Pyrenophora triticirepentis	72.76	3.00e-139	487.00
IUUC-Rno-104964	Rattus norvegicus	100.00	0.00e+00	653.00
IUUC-Sce-106224	Saccharomyces cerevisiae	53.82	5.00e-97	347.00
IUUC-Sha-107409	Sarcophilus harrisii	100.00	0.00e+00	653.00
IUUC-Sja-107971	Schizosaccharomyces japonicus	65.81	2.00e-126	444.00
IUUC-Spo-108297	Schizosaccharomyces pombe	64.22	4.00e-123	433.00
IUUC-Ssl-108479	Sclerotinia sclerotiorum	71.15	2.00e-137	481.00
IUUC-Smo-109017	Selaginella moellendorffii	69.62	1.00e-128	452.00
IUUC-Sit-110680	Setaria italica	62.77	4.00e-115	407.00
IUUC-Sly-111496	Solanum lycopersicum	68.44	6.00e-127	446.00
IUUC-Stu-112757	Solanum tuberosum	66.88	9.00e-123	432.00
IUUC-Sar-113173	Sorex araneus	100.00	0.00e+00	653.00
IUUC-Sbi-114681	Sorghum bicolor	63.08	3.00e-116	411.00
IUUC-Sre-115107	Sporisorium reilianum	70.83	1.00e-138	485.00
IUUC-Ssc-116218	Sus scrofa	95.58	1.00e-180	624.00
IUUC-Tru-118202	Takifugu rubripes	92.74	1.00e-179	621.00
IUUC-Tni-120260	Tetraodon nigroviridis	92.43	4.00e-179	619.00
IUUC-Tca-120951	Theobroma cacao	66.15	6.00e-127	446.00
IUUC-Tre-121961	Trichoderma reesei	73.40	1.00e-140	492.00
IUUC-Tvi-122447	Trichoderma virens	73.08	1.00e-139	488.00
IUUC-Tae-123560	Triticum aestivum	62.61	1.00e-114	405.00
IUUC-Tur-126335	Triticum urartu	67.78	3.00e-104	371.00
IUUC-Tme-127105	Tuber melanosporum	67.96	1.00e-125	442.00
IUUC-Tbe-128021	Tupaia belangeri	79.70	2.00e-86	310.00
IUUC-Ttr-128637	Tursiops truncatus	88.33	4.00e-162	563.00
IUUC-Uma-129634	Ustilago maydis	71.79	1.00e-139	488.00
IUUC-Vda-129923	Verticillium dahliae	72.44	4.00e-139	486.00
IUUC-Vpa-130410	Vicugna pacos	77.61	4.00e-112	397.00
IUUC-Vvi-131115	Vitis vinifera	66.67	3.00e-127	447.00
IUUC-Xtr-132105	Xenopus tropicalis	96.21	0.00e+00	641.00
IUUC-Xma-133875	Xiphophorus maculatus	94.32	0.00e+00	630.00
IUUC-Yli-134624	Yarrowia lipolytica	60.76	3.00e-119	421.00
IUUC-Zma-134711	Zea mays	63.08	3.00e-115	407.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence