iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.50e-25	89.4	484	548

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +Dv++++++   +ah++vL  +++v++a++l++++e + ++ +++ +v    f  ll++lYt++++
   Q: 484  SDVTFELDDGLMKAHRAVLVGRCDVMRAMLLGDFREAH-SNVIVFPGVTIYTFHKLLCYLYTDQIP 548
           6************************************9.************************986 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MPKMDNEQPH QELVKCVLVG DTAVGKTRLI CARACNKHVS LSQLLSTHVP TVWAIDQYRI 60
YKDVLERSWE VVDGVNVSLR LWDTFGDHDK DRRFAYGRSD VVLLCFSIAS PISLRNCKMM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGTTTTCCA ACACTGGCCG GTTGCCGTCA AAGCGCGTAG AAGAATTGCG GGCTGTAACT 60
GCAATTTATT ATTTTTTAAT TTCATTTATA GTGCACCTGG TCAGCGAGCA CTGGCTCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0342--GTP-binding
KW-0472--Membrane
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR000210--BTB/POZ_dom
IPR027417--P-loop_NTPase
IPR011333--SKP1/BTB/POZ
IPR005225--Small_GTP-bd_dom
IPR001806--Small_GTPase
IPR003578--Small_GTPase_Rho

PROSITE

PS50097--BTB
PS51420--RHO

Pfam

PF00651--BTB
PF00071--Ras

SMART

SM00225--BTB

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005622--C:intracellular
GO:0005525--F:GTP binding
GO:0035011--P:melanotic encapsulation of foreign target
GO:0007264--P:small GTPase mediated signal transduction

KEGG

dme:Dmel_CG5701

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002036	Ailuropoda melanoleuca	42.63	5.00e-125	440.00
IUUC-Apl-003214	Anas platyrhynchos	41.57	4.00e-122	431.00
IUUC-Aca-005311	Anolis carolinensis	41.13	9.00e-121	426.00
IUUC-Ame-010789	Astyanax mexicanus	40.80	1.00e-119	422.00
IUUC-Bta-013141	Bos taurus	42.12	7.00e-121	427.00
IUUC-Cja-019750	Callithrix jacchus	62.50	3.00e-73	268.00
IUUC-Cfa-021073	Canis familiaris	62.05	4.00e-72	265.00
IUUC-Cpo-021477	Cavia porcellus	62.05	3.00e-72	265.00
IUUC-Csa-023710	Chlorocebus sabaeus	62.50	5.00e-73	268.00
IUUC-Cho-024768	Choloepus hoffmanni	36.59	2.00e-88	318.00
IUUC-Cin-025684	Ciona intestinalis	33.43	8.00e-97	347.00
IUUC-Csv-026261	Ciona savignyi	51.18	1.00e-44	171.00
IUUC-Dre-028133	Danio rerio	41.12	2.00e-121	428.00
IUUC-Dno-030090	Dasypus novemcinctus	41.64	8.00e-123	433.00
IUUC-Dor-030420	Dipodomys ordii	40.62	8.00e-120	423.00
IUUC-Ete-032797	Echinops telfairi	61.61	2.00e-71	263.00
IUUC-Eca-034014	Equus caballus	42.17	1.00e-118	419.00
IUUC-Eeu-034860	Erinaceus europaeus	62.05	2.00e-72	265.00
IUUC-Fca-035800	Felis catus	39.86	1.00e-122	433.00
IUUC-Fal-037203	Ficedula albicollis	62.50	2.00e-72	265.00
IUUC-Gmo-038991	Gadus morhua	38.55	3.00e-113	401.00
IUUC-Gga-041076	Gallus gallus	41.49	9.00e-125	440.00
IUUC-Gac-042348	Gasterosteus aculeatus	40.73	1.00e-113	403.00
IUUC-Ggo-044917	Gorilla gorilla	28.15	3.00e-22	99.40
IUUC-Hsa-046839	Homo sapiens	62.95	5.00e-73	268.00
IUUC-Itr-048571	Ictidomys tridecemlineatus	61.06	5.00e-70	258.00
IUUC-Lch-050574	Latimeria chalumnae	39.92	3.00e-115	408.00
IUUC-Loc-051913	Lepisosteus oculatus	41.39	1.00e-123	436.00
IUUC-Laf-054001	Loxodonta africana	41.62	2.00e-122	432.00
IUUC-Mcc-054968	Macaca mulatta	62.50	5.00e-73	268.00
IUUC-Meu-056380	Macropus eugenii	35.09	2.00e-87	315.00
IUUC-Mga-059438	Meleagris gallopavo	38.06	1.00e-113	402.00
IUUC-Mmr-061412	Microcebus murinus	39.55	2.00e-124	438.00
IUUC-Mdo-062950	Monodelphis domestica	62.50	5.00e-72	265.00
IUUC-Mmu-064030	Mus musculus	42.06	1.00e-129	456.00
IUUC-Mpu-065787	Mustela putorius furo	42.20	4.00e-123	434.00
IUUC-Mlu-067478	Myotis lucifugus	42.05	7.00e-121	427.00
IUUC-Nle-069107	Nomascus leucogenys	62.95	6.00e-73	267.00
IUUC-Opr-070647	Ochotona princeps	37.20	5.00e-112	397.00
IUUC-Ont-071398	Oreochromis niloticus	39.09	7.00e-116	410.00
IUUC-Oan-073091	Ornithorhynchus anatinus	42.88	3.00e-126	444.00
IUUC-Ocu-074505	Oryctolagus cuniculus	41.57	3.00e-123	435.00
IUUC-Ola-086313	Oryzias latipes	40.41	1.00e-116	413.00
IUUC-Oga-088516	Otolemur garnettii	40.69	1.00e-126	446.00
IUUC-Oar-090360	Ovis aries	42.26	5.00e-124	437.00
IUUC-Ptr-090670	Pan troglodytes	62.95	7.00e-73	267.00
IUUC-Pan-091983	Papio anubis	62.50	5.00e-73	268.00
IUUC-Psi-093257	Pelodiscus sinensis	42.57	1.00e-132	466.00
IUUC-Pma-094594	Petromyzon marinus	38.04	8.00e-74	270.00
IUUC-Pfo-096190	Poecilia formosa	39.42	2.00e-112	399.00
IUUC-Pab-097809	Pongo abelii	62.95	6.00e-73	268.00
IUUC-Pca-100528	Procavia capensis	40.59	1.00e-106	379.00
IUUC-Pva-102587	Pteropus vampyrus	39.12	2.00e-116	412.00
IUUC-Pgr-136662	Puccinia graminis	33.33	3.50e-01	29.30
IUUC-Rno-105337	Rattus norvegicus	41.29	3.00e-127	448.00
IUUC-Sha-107644	Sarcophilus harrisii	62.50	4.00e-72	265.00
IUUC-Ssl-108435	Sclerotinia sclerotiorum	29.79	1.00e-05	42.70
IUUC-Sar-113152	Sorex araneus	41.37	3.00e-119	421.00
IUUC-Ssc-116044	Sus scrofa	61.06	5.00e-70	258.00
IUUC-Tgu-117136	Taeniopygia guttata	62.50	2.00e-72	266.00
IUUC-Tru-118734	Takifugu rubripes	38.13	9.00e-117	413.00
IUUC-Tsy-119544	Tarsius syrichta	56.08	3.00e-46	179.00
IUUC-Tni-120718	Tetraodon nigroviridis	34.92	2.00e-103	369.00
IUUC-Tbe-127320	Tupaia belangeri	58.04	1.00e-72	266.00
IUUC-Ttr-129079	Tursiops truncatus	42.35	4.00e-124	437.00
IUUC-Vpa-130767	Vicugna pacos	36.34	5.00e-91	327.00
IUUC-Xtr-132058	Xenopus tropicalis	55.18	2.00e-72	266.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence