iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098281

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01343851

Gene Name

ITSN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000011383.2	ENSPPYT00000013212.2	ENSPPYP00000012707.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.40e-44	147.8	1005	1055

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            ++++y ye++++++Lt+++Gdv+lv    ++d++W+ g  +   k+G+fP+n+v+
   Q: 1005 EFIAMYTYESSEQGDLTFQQGDVILVT---KKDGDWWTG--TVGDKSGVFPSNYVR 1055
           6899**********************7...*********..89***********97 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MAQFPTPFGG SLDIWAITVE ERAKHDQQFH SLKPISGFIT GDQARNFFFQ SGLPQPVLAQ 60
IWALADMNND GRMDQVEFSI AMKLIKLKLQ GYQLPSALPP VMKQQPVAIS SAPAFGMGGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGTGTTTAT GATTATACAG GAATTAAGTT TTCATAAACT TAAATGTTGC ATTTCACTTA 60
CAGGCGTCAA TTAGCAAGGT AAAAGTAACA GAACCATGGC TCAGTTTCCA ACACCTTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS00741--DH_1
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030139--C:endocytic vesicle
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0019209--F:kinase activator activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000722	Aegilops tauschii	41.67	3.00e-14	75.10
IUUC-Apl-003335	Anas platyrhynchos	80.90	0.00e+00	1895.00
IUUC-Bta-012863	Bos taurus	85.15	0.00e+00	1995.00
IUUC-Bdi-014016	Brachypodium distachyon	40.00	4.00e-14	73.90
IUUC-Cja-019012	Callithrix jacchus	87.70	0.00e+00	2070.00
IUUC-Cfa-020272	Canis familiaris	82.94	0.00e+00	1981.00
IUUC-Cpo-021352	Cavia porcellus	85.87	0.00e+00	1758.00
IUUC-Csa-024033	Chlorocebus sabaeus	88.28	0.00e+00	1995.00
IUUC-Cme-027247	Cyanidioschyzon merolae	25.43	4.00e-11	62.80
IUUC-Dno-030044	Dasypus novemcinctus	85.07	0.00e+00	2026.00
IUUC-Ete-032927	Echinops telfairi	86.87	0.00e+00	975.00
IUUC-Eca-033469	Equus caballus	85.56	0.00e+00	2014.00
IUUC-Eeu-034977	Erinaceus europaeus	92.54	0.00e+00	1145.00
IUUC-Fca-036419	Felis catus	84.76	0.00e+00	2009.00
IUUC-Fal-037236	Ficedula albicollis	77.67	0.00e+00	1845.00
IUUC-Gga-040835	Gallus gallus	80.73	0.00e+00	1928.00
IUUC-Ggo-045100	Gorilla gorilla	87.85	0.00e+00	1781.00
IUUC-Hsa-045699	Homo sapiens	88.25	0.00e+00	2134.00
IUUC-Hvu-047530	Hordeum vulgare	33.14	1.00e-14	75.50
IUUC-Itr-048773	Ictidomys tridecemlineatus	83.08	0.00e+00	2008.00
IUUC-Lpe-051250	Leersia perrieri	41.67	2.00e-14	74.70
IUUC-Laf-053608	Loxodonta africana	83.85	0.00e+00	2031.00
IUUC-Mcc-055720	Macaca mulatta	87.62	0.00e+00	2084.00
IUUC-Mla-059128	Melampsora laricipopulina	32.26	9.00e-41	163.00
IUUC-Mga-059194	Meleagris gallopavo	84.86	0.00e+00	983.00
IUUC-Mvi-060268	Microbotryum violaceum	29.02	2.00e-45	178.00
IUUC-Mmr-061258	Microcebus murinus	86.35	0.00e+00	2034.00
IUUC-Mdo-062019	Monodelphis domestica	81.76	0.00e+00	1870.00
IUUC-Mmu-063885	Mus musculus	83.41	0.00e+00	2049.00
IUUC-Mac-065649	Musa acuminata	32.77	9.00e-12	66.20
IUUC-Mpu-066402	Mustela putorius furo	91.90	0.00e+00	912.00
IUUC-Mlu-067025	Myotis lucifugus	77.70	0.00e+00	981.00
IUUC-Nle-069448	Nomascus leucogenys	92.39	0.00e+00	1129.00
IUUC-Opr-070441	Ochotona princeps	80.83	0.00e+00	1752.00
IUUC-Oan-073390	Ornithorhynchus anatinus	64.74	0.00e+00	1459.00
IUUC-Ocu-073753	Oryctolagus cuniculus	86.09	0.00e+00	2668.00
IUUC-Ogu-078849	Oryza glumaepatula	41.67	2.00e-14	74.70
IUUC-Olo-080259	Oryza longistaminata	41.67	2.00e-14	75.10
IUUC-Ome-081199	Oryza meridionalis	41.67	2.00e-14	75.10
IUUC-Oni-082167	Oryza nivara	41.67	4.00e-14	73.90
IUUC-Oru-084541	Oryza rufipogon	41.67	4.00e-14	73.90
IUUC-Olu-087698	Ostreococcus lucimarinus	27.16	2.00e-16	80.90
IUUC-Oga-088602	Otolemur garnettii	86.11	0.00e+00	2041.00
IUUC-Oar-090195	Ovis aries	85.02	0.00e+00	2007.00
IUUC-Ptr-091363	Pan troglodytes	88.33	0.00e+00	2135.00
IUUC-Pan-092385	Papio anubis	87.52	0.00e+00	2088.00
IUUC-Psi-093551	Pelodiscus sinensis	87.16	0.00e+00	1098.00
IUUC-Pca-100270	Procavia capensis	81.64	0.00e+00	842.00
IUUC-Pgr-103473	Puccinia graminis	28.76	5.00e-37	150.00
IUUC-Ptt-103973	Puccinia triticina	24.32	1.00e-25	113.00
IUUC-Rno-106122	Rattus norvegicus	82.28	0.00e+00	2004.00
IUUC-Sha-106851	Sarcophilus harrisii	81.93	0.00e+00	1881.00
IUUC-Sit-110414	Setaria italica	40.48	3.00e-14	74.30
IUUC-Sar-113421	Sorex araneus	81.51	0.00e+00	674.00
IUUC-Sbi-114170	Sorghum bicolor	38.89	2.00e-14	74.70
IUUC-Ssc-116237	Sus scrofa	88.69	0.00e+00	1075.00
IUUC-Tgu-117028	Taeniopygia guttata	78.46	0.00e+00	1882.00
IUUC-Tsy-119039	Tarsius syrichta	75.00	0.00e+00	1032.00
IUUC-Tae-123242	Triticum aestivum	41.67	4.00e-14	73.90
IUUC-Tur-126623	Triticum urartu	40.00	3.00e-14	74.30
IUUC-Tbe-127754	Tupaia belangeri	84.60	0.00e+00	1712.00
IUUC-Ttr-129178	Tursiops truncatus	85.63	0.00e+00	2022.00
IUUC-Uma-129456	Ustilago maydis	30.74	2.00e-32	135.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence