iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072933

UUCD1 version

UUC-OrA-00566

Ensembl Protein ID

ENSOANP00000019005.2

UniProt Accession

F7E5Y0; F7E5Y0_ORNAN

Protein Name

Uncharacterized protein

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000011999.2	ENSOANT00000019008.2	ENSOANP00000019005.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.10e-102	344.1	323	661

Active Site

Position(s)	Description	Evidence
629	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
            +dlkk+l+v+fvgE+gld+gG+t+e++ ll++++++pd+g+f y+++++++++   +      ++ + F+++G+l+g+a+++++ ld+
   Q: 323  TADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFAYHKDSHSHWFSGFKC-----DNYSEFRLVGILMGLAVYNSNNLDI 406
           579*************************************************9976655.....789********************** PP
   S: 91   plsksfyklllgkk..............lsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +++ ++yk+ll+ +              +s++dl +++pel++ l e++++ e ++ee  +  tf+v +e++g +k++ LkpgG++ipV
   Q: 407  HFPLCCYKKLLSPPvvpcdsnspvgicgVSIDDLYQIMPELAHGLSELLSY-EGNVEED-FYSTFQVFQEEFGVIKSYSLKPGGDKIPV 493
           ************9555566666666667**********************9.6788885.***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           tn+N++eYv+l++++ l+++i +q++af+ Gf++v+  + l l+++ee+e+l+cG++++d+++l+++t+y+ gy +++ +i++Fw+v+ 
   Q: 494  TNQNRKEYVQLYIDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVEILVCGSPQLDMHALQRNTQYE-GYVKTDLTIRYFWDVVL 581
           **********************************************************************5.5**************** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           efs + +k++L+F+Tgs+r+P+gG+a+l+   f i+k ++s+++lP ++TCfn+L+LP+Y++k++l++kL++ i++++gF+l+
   Q: 582  EFSLDLQKKLLHFTTGSDRVPVGGMADLN---FKISKnETSTNWLPVAHTCFNQLCLPPYKNKKELRQKLIIGISNSEGFGLE 661
           *****************************...9999967777**************************************985 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MKAPTPAEPA LPLLNKTIQN FQENVEKVKS SGEWKAVHDF YLTTFDSFLQ LNAAFKKDAN 60
APFNTTEDSG INAQFVNAVY DALLNTPQDI QKSVLKGIIN SLLMEWKGPR IKDDLRAYFI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAGAACTCA TAACTATCAG TTTTCTTTTT TGTGCTACAC AGGGAGAGAG CGACCACCGA 60
TTTGCCTTGA TGTGAGACAA AAACAACGTG TCTCTCCAGA CGCTTTGCCT CCTGAAATGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	88.74	0.00e+00	1233.00
IUUC-Atr-003144	Amborella trichopoda	39.16	1.00e-90	325.00
IUUC-Apl-003589	Anas platyrhynchos	86.56	0.00e+00	1186.00
IUUC-Aca-004350	Anolis carolinensis	82.18	0.00e+00	1138.00
IUUC-Ago-007908	Ashbya gossypii	35.66	3.00e-84	306.00
IUUC-Acl-008288	Aspergillus clavatus	34.93	5.00e-98	352.00
IUUC-Afl-008402	Aspergillus flavus	34.05	5.00e-92	331.00
IUUC-Afu-008762	Aspergillus fumigatus	34.21	5.00e-95	342.00
IUUC-Ani-009176	Aspergillus nidulans	34.94	6.00e-94	338.00
IUUC-Ang-009791	Aspergillus niger	35.60	2.00e-94	340.00
IUUC-Aor-009921	Aspergillus oryzae	33.89	7.00e-91	327.00
IUUC-Ate-010295	Aspergillus terreus	35.54	8.00e-101	361.00
IUUC-Ame-010660	Astyanax mexicanus	80.27	4.00e-148	516.00
IUUC-Bgr-011981	Blumeria graminis	37.50	1.00e-91	330.00
IUUC-Bta-012945	Bos taurus	87.76	0.00e+00	1202.00
IUUC-Bci-013697	Botrytis cinerea	32.90	4.00e-82	299.00
IUUC-Cja-019263	Callithrix jacchus	87.39	0.00e+00	1195.00
IUUC-Cfa-020486	Canis familiaris	89.30	0.00e+00	1214.00
IUUC-Cpo-021755	Cavia porcellus	88.22	0.00e+00	1230.00
IUUC-Csa-023814	Chlorocebus sabaeus	88.28	0.00e+00	1130.00
IUUC-Cho-024980	Choloepus hoffmanni	71.41	0.00e+00	941.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	42.07	3.00e-97	349.00
IUUC-Cme-027151	Cyanidioschyzon merolae	40.57	4.00e-85	309.00
IUUC-Dre-028551	Danio rerio	78.40	0.00e+00	1067.00
IUUC-Dno-029497	Dasypus novemcinctus	85.56	0.00e+00	1145.00
IUUC-Dor-030867	Dipodomys ordii	75.38	0.00e+00	995.00
IUUC-Dse-031239	Dothistroma septosporum	31.88	3.00e-87	316.00
IUUC-Ete-032902	Echinops telfairi	84.90	0.00e+00	1028.00
IUUC-Eca-033678	Equus caballus	88.67	0.00e+00	1222.00
IUUC-Eeu-035262	Erinaceus europaeus	73.11	0.00e+00	960.00
IUUC-Fca-035590	Felis catus	88.67	0.00e+00	1237.00
IUUC-Fal-037123	Ficedula albicollis	83.21	0.00e+00	1128.00
IUUC-Fox-037941	Fusarium oxysporum	40.12	6.00e-101	362.00
IUUC-Fso-038388	Fusarium solani	41.15	3.00e-103	369.00
IUUC-Gmo-039553	Gadus morhua	66.25	0.00e+00	850.00
IUUC-Ggr-040110	Gaeumannomyces graminis	35.42	3.00e-99	356.00
IUUC-Gga-040406	Gallus gallus	87.01	0.00e+00	1221.00
IUUC-Gac-042141	Gasterosteus aculeatus	75.68	0.00e+00	1067.00
IUUC-Ggo-045504	Gorilla gorilla	87.54	0.00e+00	1199.00
IUUC-Hsa-045786	Homo sapiens	88.07	0.00e+00	1204.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	81.93	0.00e+00	1108.00
IUUC-Kpa-049152	Komagataella pastoris	32.62	6.00e-77	281.00
IUUC-Lch-049824	Latimeria chalumnae	82.71	0.00e+00	1028.00
IUUC-Loc-052173	Lepisosteus oculatus	82.15	0.00e+00	1142.00
IUUC-Lma-053245	Leptosphaeria maculans	34.93	8.00e-52	199.00
IUUC-Laf-054017	Loxodonta africana	88.37	0.00e+00	1213.00
IUUC-Mcc-055713	Macaca mulatta	87.99	0.00e+00	1201.00
IUUC-Meu-056212	Macropus eugenii	68.83	9.00e-114	403.00
IUUC-Mor-057045	Magnaporthe oryzae	35.71	4.00e-90	326.00
IUUC-Mla-059187	Melampsora laricipopulina	44.04	2.00e-91	328.00
IUUC-Mga-059884	Meleagris gallopavo	79.37	0.00e+00	1074.00
IUUC-Mmr-061344	Microcebus murinus	87.75	0.00e+00	1219.00
IUUC-Mdo-062653	Monodelphis domestica	88.97	0.00e+00	1219.00
IUUC-Mmu-063775	Mus musculus	86.71	0.00e+00	1148.00
IUUC-Mpu-066069	Mustela putorius furo	88.82	0.00e+00	1232.00
IUUC-Mlu-067925	Myotis lucifugus	88.22	0.00e+00	1214.00
IUUC-Nfi-068439	Neosartorya fischeri	34.21	8.00e-95	341.00
IUUC-Ncr-068903	Neurospora crassa	38.23	4.00e-94	339.00
IUUC-Nle-070046	Nomascus leucogenys	87.84	0.00e+00	1221.00
IUUC-Opr-071085	Ochotona princeps	73.83	4.00e-128	451.00
IUUC-Ont-072126	Oreochromis niloticus	76.59	0.00e+00	1090.00
IUUC-Ocu-073800	Oryctolagus cuniculus	88.97	0.00e+00	1224.00
IUUC-Ola-086988	Oryzias latipes	75.72	0.00e+00	1077.00
IUUC-Oga-088117	Otolemur garnettii	88.97	0.00e+00	1065.00
IUUC-Oar-089371	Ovis aries	87.76	0.00e+00	1182.00
IUUC-Ptr-090551	Pan troglodytes	87.54	0.00e+00	1199.00
IUUC-Pan-092067	Papio anubis	88.52	0.00e+00	1206.00
IUUC-Psi-092963	Pelodiscus sinensis	86.83	0.00e+00	1170.00
IUUC-Pfo-096562	Poecilia formosa	74.77	0.00e+00	1066.00
IUUC-Pab-098680	Pongo abelii	88.22	0.00e+00	1204.00
IUUC-Pca-100986	Procavia capensis	70.83	0.00e+00	841.00
IUUC-Pva-102219	Pteropus vampyrus	78.83	0.00e+00	964.00
IUUC-Pgr-103315	Puccinia graminis	35.66	1.00e-99	357.00
IUUC-Ptt-103736	Puccinia triticina	41.79	9.00e-97	347.00
IUUC-Rno-105270	Rattus norvegicus	87.15	0.00e+00	1150.00
IUUC-Sce-106306	Saccharomyces cerevisiae	34.65	7.00e-70	258.00
IUUC-Sha-106819	Sarcophilus harrisii	88.84	0.00e+00	1237.00
IUUC-Spo-108271	Schizosaccharomyces pombe	33.69	1.00e-87	317.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	33.06	1.00e-85	311.00
IUUC-Smo-108858	Selaginella moellendorffii	38.77	8.00e-111	394.00
IUUC-Sar-113134	Sorex araneus	79.91	0.00e+00	1055.00
IUUC-Ssc-115441	Sus scrofa	88.39	0.00e+00	1201.00
IUUC-Tgu-117166	Taeniopygia guttata	86.55	0.00e+00	1158.00
IUUC-Tsy-118898	Tarsius syrichta	76.24	0.00e+00	974.00
IUUC-Tre-122108	Trichoderma reesei	37.48	3.00e-89	323.00
IUUC-Tvi-122644	Trichoderma virens	37.75	3.00e-94	339.00
IUUC-Tme-127004	Tuber melanosporum	34.62	8.00e-104	371.00
IUUC-Tbe-127292	Tupaia belangeri	72.21	0.00e+00	927.00
IUUC-Ttr-128352	Tursiops truncatus	84.74	0.00e+00	1141.00
IUUC-Vda-129969	Verticillium dahliae	40.09	2.00e-93	337.00
IUUC-Vpa-130218	Vicugna pacos	86.62	0.00e+00	830.00
IUUC-Xtr-132594	Xenopus tropicalis	77.64	0.00e+00	1040.00
IUUC-Xma-134157	Xiphophorus maculatus	74.64	0.00e+00	994.00
IUUC-Yli-134470	Yarrowia lipolytica	34.88	6.00e-79	288.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence