iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036649

Ensembl Protein ID

ENSFALP00000012638.1

UniProt Accession

U3KC84; U3KC84_FICAL

Genbank Protein ID

ENSFALP00000012638

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01001512

Gene Name

HGS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000012102.1	ENSFALT00000012688.1	ENSFALP00000012638.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UIM	83.99	0.00e+00	1038.00	IUUC-Bta-012506
UBD/Alpha-Helix/UIM	44.79	4.00e-103	373.00	IUUC-Dme-031952
UBD/Alpha-Helix/DUIM	83.05	0.00e+00	1030.00	IUUC-Hsa-046009
UBD/Alpha-Helix/VHS	83.05	0.00e+00	1030.00	IUUC-Hsa-046009
UBD/Alpha-Helix/UIM	83.87	0.00e+00	1039.00	IUUC-Mmu-063952
UBD/Alpha-Helix/VHS	83.17	0.00e+00	1028.00	IUUC-Rno-105125
UBD/Alpha-Helix/UIM	29.08	2.00e-24	108.00	IUUC-Sce-106192
UBD/Alpha-Helix/UIM	36.27	2.00e-35	145.00	IUUC-Spo-108220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MIRQGDTQAK YAVNAIKKKV NDKNPHVALY ALEVMESVVK NCGQTVHDEV ANKQTMEELK 60
EILKRQVETS VRSKILYLIQ AWAHAFRNEP KYKVVQDTYQ IMKVEGHVFP EFKESDAMFA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG 60
GGGTCGGAGC TGTCCGGTGA AATCGCGGTT TGTCCCCGAG GCTCGGGCAG CGCTCGCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR024641--HRS_helical
IPR017073--Ubi-bd_Hrs_VPS27
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF12210--Hrs_helical
PF00790--VHS

SMART

SM00064--FYVE
SM00288--VHS

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0005764--C:lysosome
GO:0046872--F:metal ion binding
GO:0010324--P:membrane invagination
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:1903543--P:positive regulation of exosomal secretion
GO:0010628--P:positive regulation of gene expression
GO:0072657--P:protein localization to membrane
GO:0006622--P:protein targeting to lysosome
GO:0043405--P:regulation of MAP kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001518	Ailuropoda melanoleuca	78.78	0.00e+00	868.00
IUUC-Apl-003662	Anas platyrhynchos	92.21	0.00e+00	1062.00
IUUC-Aca-004940	Anolis carolinensis	85.53	0.00e+00	1144.00
IUUC-Ago-007931	Ashbya gossypii	31.79	3.00e-25	110.00
IUUC-Acl-008274	Aspergillus clavatus	29.03	6.00e-36	145.00
IUUC-Afl-008521	Aspergillus flavus	26.96	1.00e-38	154.00
IUUC-Afu-008774	Aspergillus fumigatus	31.05	3.00e-37	149.00
IUUC-Ani-009445	Aspergillus nidulans	32.40	9.00e-39	154.00
IUUC-Ang-009863	Aspergillus niger	31.45	1.00e-38	154.00
IUUC-Ate-010444	Aspergillus terreus	34.40	2.00e-39	157.00
IUUC-Ame-011111	Astyanax mexicanus	81.74	0.00e+00	906.00
IUUC-Bgr-012087	Blumeria graminis	26.54	5.00e-38	152.00
IUUC-Bta-012506	Bos taurus	84.18	0.00e+00	1032.00
IUUC-Bci-013782	Botrytis cinerea	31.98	8.00e-38	151.00
IUUC-Cel-018493	Caenorhabditis elegans	39.84	8.00e-84	304.00
IUUC-Cja-019998	Callithrix jacchus	81.29	0.00e+00	939.00
IUUC-Cfa-020615	Canis familiaris	80.22	0.00e+00	932.00
IUUC-Cpo-022019	Cavia porcellus	82.93	0.00e+00	1059.00
IUUC-Cre-022770	Chlamydomonas reinhardtii	42.65	2.00e-10	61.20
IUUC-Csa-023596	Chlorocebus sabaeus	82.82	0.00e+00	942.00
IUUC-Cin-025488	Ciona intestinalis	47.79	3.00e-118	418.00
IUUC-Csv-025802	Ciona savignyi	50.89	6.00e-109	387.00
IUUC-Cgl-026560	Colletotrichum gloeosporioides	34.66	8.00e-38	151.00
IUUC-Cne-026847	Cryptococcus neoformans	34.95	5.00e-34	139.00
IUUC-Dre-028353	Danio rerio	80.46	0.00e+00	895.00
IUUC-Dno-029005	Dasypus novemcinctus	81.07	0.00e+00	995.00
IUUC-Dor-030280	Dipodomys ordii	81.52	0.00e+00	1005.00
IUUC-Dse-031238	Dothistroma septosporum	39.49	6.00e-41	162.00
IUUC-Dme-031952	Drosophila melanogaster	46.84	2.00e-91	330.00
IUUC-Ete-032235	Echinops telfairi	94.65	3.00e-110	392.00
IUUC-Eca-033873	Equus caballus	84.65	0.00e+00	1022.00
IUUC-Eeu-034652	Erinaceus europaeus	95.89	5.00e-85	308.00
IUUC-Fca-036563	Felis catus	80.79	0.00e+00	974.00
IUUC-Fox-037962	Fusarium oxysporum	31.58	7.00e-36	145.00
IUUC-Fso-038396	Fusarium solani	32.27	4.00e-36	145.00
IUUC-Gmo-039510	Gadus morhua	76.73	0.00e+00	882.00
IUUC-Ggr-039938	Gaeumannomyces graminis	32.39	1.00e-34	141.00
IUUC-Gga-040201	Gallus gallus	95.21	0.00e+00	1177.00
IUUC-Gac-041459	Gasterosteus aculeatus	77.91	0.00e+00	910.00
IUUC-Ggo-044573	Gorilla gorilla	83.52	0.00e+00	1008.00
IUUC-Hsa-046009	Homo sapiens	83.24	0.00e+00	1050.00
IUUC-Itr-049065	Ictidomys tridecemlineatus	82.96	0.00e+00	1070.00
IUUC-Kpa-049327	Komagataella pastoris	31.03	1.00e-28	121.00
IUUC-Lch-049944	Latimeria chalumnae	83.89	5.00e-171	593.00
IUUC-Loc-051850	Lepisosteus oculatus	84.66	0.00e+00	1003.00
IUUC-Lma-053252	Leptosphaeria maculans	35.53	2.00e-38	154.00
IUUC-Laf-053346	Loxodonta africana	78.06	0.00e+00	901.00
IUUC-Mcc-055789	Macaca mulatta	83.24	0.00e+00	1004.00
IUUC-Meu-056329	Macropus eugenii	68.93	6.00e-152	530.00
IUUC-Mor-057205	Magnaporthe oryzae	32.95	2.00e-35	143.00
IUUC-Mpo-057295	Magnaporthe poae	31.91	2.00e-37	150.00
IUUC-Mla-058849	Melampsora laricipopulina	32.67	1.00e-29	125.00
IUUC-Mga-059361	Meleagris gallopavo	92.01	0.00e+00	1123.00
IUUC-Mvi-060561	Microbotryum violaceum	36.63	3.00e-33	136.00
IUUC-Mmr-061122	Microcebus murinus	87.52	0.00e+00	883.00
IUUC-Mdo-062171	Monodelphis domestica	86.32	0.00e+00	1086.00
IUUC-Mmu-063952	Mus musculus	83.87	0.00e+00	1098.00
IUUC-Mpu-065852	Mustela putorius furo	80.81	0.00e+00	942.00
IUUC-Mlu-066996	Myotis lucifugus	71.69	3.00e-126	444.00
IUUC-Nfi-068539	Neosartorya fischeri	31.05	1.00e-37	150.00
IUUC-Ncr-068726	Neurospora crassa	38.22	6.00e-36	145.00
IUUC-Nle-070148	Nomascus leucogenys	78.23	0.00e+00	899.00
IUUC-Opr-070833	Ochotona princeps	63.92	4.00e-124	438.00
IUUC-Ont-071261	Oreochromis niloticus	80.09	0.00e+00	920.00
IUUC-Oan-073684	Ornithorhynchus anatinus	73.26	8.00e-144	503.00
IUUC-Ola-087570	Oryzias latipes	75.35	0.00e+00	912.00
IUUC-Oga-089087	Otolemur garnettii	83.97	0.00e+00	986.00
IUUC-Oar-089534	Ovis aries	83.90	0.00e+00	1029.00
IUUC-Ptr-091654	Pan troglodytes	78.03	0.00e+00	905.00
IUUC-Pan-092652	Papio anubis	83.24	0.00e+00	1006.00
IUUC-Pno-095125	Phaeosphaeria nodorum	37.37	8.00e-38	151.00
IUUC-Pfo-096757	Poecilia formosa	78.25	0.00e+00	882.00
IUUC-Pab-097788	Pongo abelii	86.04	0.00e+00	705.00
IUUC-Pca-100145	Procavia capensis	73.74	0.00e+00	814.00
IUUC-Pva-102965	Pteropus vampyrus	80.20	0.00e+00	957.00
IUUC-Pgr-103609	Puccinia graminis	34.03	2.00e-32	133.00
IUUC-Ptt-103865	Puccinia triticina	35.29	5.00e-33	136.00
IUUC-Pte-104095	Pyrenophora teres	34.52	3.00e-37	150.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	35.03	2.00e-37	150.00
IUUC-Rno-105125	Rattus norvegicus	83.17	0.00e+00	1018.00
IUUC-Sce-106192	Saccharomyces cerevisiae	28.87	1.00e-25	110.00
IUUC-Sha-107066	Sarcophilus harrisii	87.21	0.00e+00	1055.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	32.94	2.00e-37	150.00
IUUC-Spo-108220	Schizosaccharomyces pombe	33.88	1.00e-36	147.00
IUUC-Stu-112464	Solanum tuberosum	45.90	2.00e-13	71.60
IUUC-Sar-113393	Sorex araneus	90.59	8.00e-94	337.00
IUUC-Sre-114986	Sporisorium reilianum	38.95	9.00e-38	152.00
IUUC-Tgu-117505	Taeniopygia guttata	93.82	0.00e+00	1113.00
IUUC-Tru-118494	Takifugu rubripes	77.97	0.00e+00	947.00
IUUC-Tsy-119626	Tarsius syrichta	97.80	7.00e-49	188.00
IUUC-Tni-120174	Tetraodon nigroviridis	77.61	0.00e+00	947.00
IUUC-Tre-122191	Trichoderma reesei	32.02	1.00e-36	147.00
IUUC-Tvi-122318	Trichoderma virens	31.62	1.00e-36	148.00
IUUC-Tme-126914	Tuber melanosporum	34.78	8.00e-42	164.00
IUUC-Ttr-129095	Tursiops truncatus	84.49	0.00e+00	1055.00
IUUC-Uma-129475	Ustilago maydis	36.13	1.00e-33	138.00
IUUC-Vda-129908	Verticillium dahliae	31.33	6.00e-33	135.00
IUUC-Xtr-131900	Xenopus tropicalis	80.28	0.00e+00	1003.00
IUUC-Xma-133124	Xiphophorus maculatus	79.07	0.00e+00	927.00
IUUC-Yli-134682	Yarrowia lipolytica	31.85	1.00e-28	120.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence