iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050662

Ensembl Protein ID

ENSLACP00000014363.1

UniProt Accession

H3AXJ2; H3AXJ2_LATCH

Genbank Protein ID

ENSLACP00000014363

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01152196

Gene Name

USP30

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000012641.1	ENSLACT00000014463.1	ENSLACP00000014363.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.20e-67	226.2	39	466

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ L+++p + + l + + +   +en++ ++  l+ +l +l+++l    ++++  ++   ll++l+++  ++s +
   Q: 39   GLLNLGNTCFMNSLLQGLAACPAFIRWLEDFTAQYNIDENQELQHPYLSVTLLRLLKALSnqeETEDDIIDAGCLLEVLRMYRWQISLF 127
           9*****************************44444444556677789999*********877788888********************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknkslisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E++++l ++le+e     + ++ ++++  + e++ e          +   +++ ++   ++ F+g+l+s+++c+ c+++s  r
   Q: 128  EEQDAHELFHVLTSSLEDER--DCEPRVPHLFDVYSLESQTEtgqkqihcrsRGPPQPMPSHWRSQHPFHGRLTSNMVCKGCEQQSpIR 214
           *****************999..4455555555555555555533333344334555666666999************************ PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqe...............aekklklkklPevLilhLkRfsf 239
           +++f +lsl++p  +  ++ +l++cL++f ++e++++   + ce+c+k q                 +k+lkl klP++L++hL+R ++
   Q: 215  YDTFDSLSLSIPTGSWGQPVTLDHCLQHFISTESIKD---VVCENCTKAQAegtineetvenqrttFVKQLKLGKLPQCLCIHLQRLTW 300
           ***********************************97...9******6666666666666777777*********************** PP
   S: 240  seeqksrekinkkvefpleLdlspfctspeekqke...................................................... 274
           s++ + ++k +++v+f++ L l+ +  +++  ++                                                       
   Q: 301  SSQ-GTPIKRHEHVQFNEFLPLDTYKYRNTGHKSGqhrlhrrgsagdqselqdgallqtsasnhasdkssvangacssssllpfatssl 388
           986.999**********998888877773333332556777777777777777777777777778888888889999999999999999 PP
   S: 275  .........kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                     + ++L+avvvH+G ++sGH+v+y ++          +++Wl ++D++V+  + +ev +   s+aY+lfY+r
   Q: 389  pvatdygssMYLFRLMAVVVHHGDMHSGHFVTYRRSpssskspaaISNQWLWISDDSVRRASLQEVFS---SNAYLLFYER 466
           9999999889999***********************8887777777888*******************...********98 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MMKNWGVIGG IAAALAAGIY VLWGPITERK KRRKGLVPGL LNLGNTCFMN SLLQGLAACP 60
AFIRWLEDFT AQYNIDENQE LQHPYLSVTL LRLLKALSNQ EETEDDIIDA GCLLEVLRMY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGTGGTCC TGGGGCTTTC GGTTCCGTTT CCCTGCGCCG AGGTATGCGG AGCGGAGCCG 60
AGGCCGCCCG CTGGCTGGCC AATGCCATGC AGCTGCTGCG GACCGGGACC GCGGTCAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	26.33	2.00e-18	87.40
IUUC-Aml-001733	Ailuropoda melanoleuca	70.53	3.00e-175	607.00
IUUC-Atr-002510	Amborella trichopoda	27.01	7.00e-25	108.00
IUUC-Apl-003645	Anas platyrhynchos	67.44	7.00e-95	339.00
IUUC-Aca-004583	Anolis carolinensis	71.64	6.00e-20	88.20
IUUC-Aly-005754	Arabidopsis lyrata	25.47	3.00e-21	96.30
IUUC-Ath-007622	Arabidopsis thaliana	25.77	4.00e-22	99.00
IUUC-Acl-008136	Aspergillus clavatus	21.88	3.00e-12	66.60
IUUC-Ang-009829	Aspergillus niger	22.92	3.00e-11	63.50
IUUC-Ate-010439	Aspergillus terreus	24.19	4.00e-14	73.20
IUUC-Ame-010896	Astyanax mexicanus	64.26	2.00e-165	575.00
IUUC-Bgr-012133	Blumeria graminis	24.89	8.00e-08	52.40
IUUC-Bta-012321	Bos taurus	70.55	9.00e-176	609.00
IUUC-Bci-013641	Botrytis cinerea	24.17	3.00e-15	76.60
IUUC-Bol-015637	Brassica oleracea	24.74	8.00e-23	101.00
IUUC-Bra-016801	Brassica rapa	25.00	1.00e-23	103.00
IUUC-Cel-018308	Caenorhabditis elegans	28.29	6.00e-37	148.00
IUUC-Cja-018826	Callithrix jacchus	71.10	0.00e+00	627.00
IUUC-Cfa-021206	Canis familiaris	71.37	2.00e-176	612.00
IUUC-Cpo-021343	Cavia porcellus	71.40	7.00e-176	610.00
IUUC-Csa-023419	Chlorocebus sabaeus	71.88	0.00e+00	630.00
IUUC-Cho-024475	Choloepus hoffmanni	64.96	1.00e-93	336.00
IUUC-Cgl-026463	Colletotrichum gloeosporioides	23.13	4.00e-12	66.20
IUUC-Cne-027061	Cryptococcus neoformans	29.46	1.00e-14	75.10
IUUC-Dre-027563	Danio rerio	63.91	7.00e-165	573.00
IUUC-Dno-029929	Dasypus novemcinctus	71.61	8.00e-178	616.00
IUUC-Dor-030166	Dipodomys ordii	63.77	2.00e-147	515.00
IUUC-Dse-031517	Dothistroma septosporum	22.54	4.00e-13	69.70
IUUC-Dme-031627	Drosophila melanogaster	32.20	7.00e-34	138.00
IUUC-Ete-032634	Echinops telfairi	65.82	4.00e-158	551.00
IUUC-Eca-033968	Equus caballus	71.40	1.00e-175	609.00
IUUC-Eeu-035279	Erinaceus europaeus	72.39	4.00e-50	192.00
IUUC-Fca-036525	Felis catus	71.19	0.00e+00	627.00
IUUC-Fal-036606	Ficedula albicollis	67.54	3.00e-144	504.00
IUUC-Fox-037837	Fusarium oxysporum	23.49	4.00e-14	73.20
IUUC-Fso-038234	Fusarium solani	23.36	3.00e-14	73.20
IUUC-Gmo-038726	Gadus morhua	57.91	1.00e-138	486.00
IUUC-Gga-040718	Gallus gallus	71.39	9.00e-150	522.00
IUUC-Gac-042645	Gasterosteus aculeatus	61.68	4.00e-153	534.00
IUUC-Gma-043364	Glycine max	25.66	6.00e-23	102.00
IUUC-Ggo-045021	Gorilla gorilla	72.09	0.00e+00	632.00
IUUC-Hsa-045832	Homo sapiens	72.09	0.00e+00	632.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	72.03	6.00e-179	620.00
IUUC-Kpa-049268	Komagataella pastoris	22.68	1.00e-17	84.70
IUUC-Lpe-051078	Leersia perrieri	27.63	5.00e-30	125.00
IUUC-Loc-052611	Lepisosteus oculatus	68.64	3.00e-174	604.00
IUUC-Lma-053048	Leptosphaeria maculans	21.63	4.00e-14	73.60
IUUC-Laf-053752	Loxodonta africana	71.61	2.00e-176	612.00
IUUC-Mcc-054892	Macaca mulatta	72.09	0.00e+00	632.00
IUUC-Meu-056673	Macropus eugenii	65.38	3.00e-129	454.00
IUUC-Mor-057143	Magnaporthe oryzae	22.76	2.00e-09	58.20
IUUC-Mtr-057976	Medicago truncatula	27.59	8.00e-35	141.00
IUUC-Mla-058970	Melampsora laricipopulina	25.20	2.00e-25	110.00
IUUC-Mga-059543	Meleagris gallopavo	71.20	1.00e-172	598.00
IUUC-Mmr-061534	Microcebus murinus	70.89	2.00e-180	625.00
IUUC-Mdo-062140	Monodelphis domestica	60.54	5.00e-137	481.00
IUUC-Mmu-063673	Mus musculus	69.70	7.00e-172	596.00
IUUC-Mpu-066328	Mustela putorius furo	70.76	2.00e-175	608.00
IUUC-Mlu-067938	Myotis lucifugus	71.82	0.00e+00	634.00
IUUC-Nle-069426	Nomascus leucogenys	69.39	2.00e-165	575.00
IUUC-Opr-070796	Ochotona princeps	64.49	3.00e-81	295.00
IUUC-Ont-072248	Oreochromis niloticus	66.24	4.00e-160	557.00
IUUC-Oan-072916	Ornithorhynchus anatinus	72.65	0.00e+00	641.00
IUUC-Ocu-074459	Oryctolagus cuniculus	66.04	8.00e-139	486.00
IUUC-Oba-075765	Oryza barthii	25.88	9.00e-29	121.00
IUUC-Obr-076005	Oryza brachyantha	27.59	3.00e-31	129.00
IUUC-Ogl-077916	Oryza glaberrima	26.38	2.00e-32	133.00
IUUC-Ogu-078263	Oryza glumaepatula	27.03	5.00e-30	125.00
IUUC-Oin-080096	Oryza indica	27.30	3.00e-20	92.80
IUUC-Ome-081928	Oryza meridionalis	26.47	1.00e-29	124.00
IUUC-Oni-082424	Oryza nivara	27.03	1.00e-29	124.00
IUUC-Oru-085117	Oryza rufipogon	27.03	1.00e-29	124.00
IUUC-Ola-087429	Oryzias latipes	58.99	5.00e-144	504.00
IUUC-Oga-087981	Otolemur garnettii	70.55	6.00e-180	623.00
IUUC-Oar-089927	Ovis aries	70.97	6.00e-177	613.00
IUUC-Ptr-090878	Pan troglodytes	72.09	0.00e+00	632.00
IUUC-Pan-092698	Papio anubis	72.09	0.00e+00	632.00
IUUC-Psi-093451	Pelodiscus sinensis	71.19	1.00e-177	615.00
IUUC-Pno-094802	Phaeosphaeria nodorum	21.53	1.00e-11	64.30
IUUC-Ppa-096015	Physcomitrella patens	23.77	4.00e-12	66.60
IUUC-Pfo-096096	Poecilia formosa	61.60	1.00e-150	526.00
IUUC-Pab-098676	Pongo abelii	71.04	2.00e-178	618.00
IUUC-Pca-100418	Procavia capensis	76.45	6.00e-104	370.00
IUUC-Ppe-101898	Prunus persica	25.82	2.00e-28	120.00
IUUC-Pva-103018	Pteropus vampyrus	69.92	1.00e-172	599.00
IUUC-Pgr-103423	Puccinia graminis	28.27	1.00e-09	58.50
IUUC-Pte-104330	Pyrenophora teres	23.17	5.00e-15	75.90
IUUC-Pyt-104518	Pyrenophora triticirepentis	22.82	2.00e-17	84.00
IUUC-Rno-105708	Rattus norvegicus	70.34	5.00e-172	597.00
IUUC-Sha-106971	Sarcophilus harrisii	72.52	0.00e+00	630.00
IUUC-Ssl-108648	Sclerotinia sclerotiorum	22.34	4.00e-16	79.70
IUUC-Sit-110442	Setaria italica	26.32	5.00e-24	105.00
IUUC-Sly-110928	Solanum lycopersicum	24.72	1.00e-15	77.80
IUUC-Stu-112223	Solanum tuberosum	25.14	1.00e-16	80.50
IUUC-Ssc-116397	Sus scrofa	70.13	2.00e-174	605.00
IUUC-Tgu-117446	Taeniopygia guttata	66.24	1.00e-174	605.00
IUUC-Tru-118268	Takifugu rubripes	60.50	7.00e-144	503.00
IUUC-Tsy-119484	Tarsius syrichta	81.33	2.00e-27	117.00
IUUC-Tni-119735	Tetraodon nigroviridis	58.31	2.00e-124	439.00
IUUC-Tca-121660	Theobroma cacao	27.02	5.00e-27	115.00
IUUC-Tre-121937	Trichoderma reesei	22.57	2.00e-15	77.80
IUUC-Tvi-122428	Trichoderma virens	23.30	3.00e-14	73.20
IUUC-Tae-125383	Triticum aestivum	26.65	3.00e-26	113.00
IUUC-Tur-126458	Triticum urartu	26.38	5.00e-24	105.00
IUUC-Tbe-127740	Tupaia belangeri	65.89	7.00e-156	543.00
IUUC-Ttr-129273	Tursiops truncatus	69.07	1.00e-168	586.00
IUUC-Vda-129789	Verticillium dahliae	23.01	5.00e-08	53.10
IUUC-Vvi-131177	Vitis vinifera	24.81	7.00e-24	105.00
IUUC-Xtr-132374	Xenopus tropicalis	67.74	9.00e-174	603.00
IUUC-Xma-133267	Xiphophorus maculatus	61.95	1.00e-159	556.00
IUUC-Yli-134426	Yarrowia lipolytica	24.43	4.00e-05	43.10
IUUC-Zma-135796	Zea mays	26.04	7.00e-25	108.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence