iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098253

Ensembl Protein ID

ENSPPYP00000006275.2

UniProt Accession

H2NKB7; H2NKB7_PONAB

Genbank Protein ID

ENSPPYP00000006275

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

ABGA01163700

Gene Name

ING1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000005505.2	ENSPPYT00000006523.2	ENSPPYP00000006275.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.30e-09	36.5	211	258

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 211  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 258
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MLSPANGEQL HLVNYVEDYL DSIESLPFDL QRNVSLMREI DAKYQEILKE LDECYERFSR 60
ETDGAQKRRM LHCVQRALIR SQELGDEKIQ IVSQMVELVE NRTRQVDSHV ELFEAQQELG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGAGTC CTGCCAACGG GGAGCAGCTC CACCTGGTGA ACTATGTGGA GGACTACCTG 60
GACTCCATCG AGTCCCTGCC TTTCGACTTG CAGAGAAATG TCTCGCTGAT GCGGGAGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	90.32	1.00e-125	442.00
IUUC-Apl-003910	Anas platyrhynchos	90.29	2.00e-123	434.00
IUUC-Aca-004874	Anolis carolinensis	88.21	1.00e-119	421.00
IUUC-Ame-011262	Astyanax mexicanus	68.28	9.00e-96	343.00
IUUC-Bta-013507	Bos taurus	87.61	4.00e-89	320.00
IUUC-Bol-015245	Brassica oleracea	81.82	1.00e-28	119.00
IUUC-Bra-017027	Brassica rapa	81.82	1.00e-28	119.00
IUUC-Cja-018925	Callithrix jacchus	99.28	3.00e-137	480.00
IUUC-Cfa-020947	Canis familiaris	89.96	2.00e-124	437.00
IUUC-Cpo-022286	Cavia porcellus	87.29	9.00e-96	343.00
IUUC-Cre-022920	Chlamydomonas reinhardtii	30.37	2.00e-29	122.00
IUUC-Csa-023825	Chlorocebus sabaeus	98.92	7.00e-137	479.00
IUUC-Cho-024577	Choloepus hoffmanni	88.84	3.00e-96	344.00
IUUC-Cne-027005	Cryptococcus neoformans	45.95	3.00e-16	79.00
IUUC-Dno-029834	Dasypus novemcinctus	90.68	2.00e-125	441.00
IUUC-Dor-030315	Dipodomys ordii	87.61	1.00e-105	376.00
IUUC-Ete-032408	Echinops telfairi	86.38	3.00e-90	325.00
IUUC-Eca-034244	Equus caballus	88.03	1.00e-97	348.00
IUUC-Fca-035391	Felis catus	85.71	2.00e-105	374.00
IUUC-Fal-036838	Ficedula albicollis	89.25	1.00e-122	432.00
IUUC-Fox-037925	Fusarium oxysporum	64.71	1.00e-19	90.90
IUUC-Gga-040619	Gallus gallus	89.61	1.00e-122	432.00
IUUC-Gac-041996	Gasterosteus aculeatus	65.85	1.00e-95	342.00
IUUC-Ggo-045481	Gorilla gorilla	98.31	6.00e-110	390.00
IUUC-Hsa-046170	Homo sapiens	98.31	7.00e-110	390.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	90.60	3.00e-99	353.00
IUUC-Lch-050397	Latimeria chalumnae	86.02	1.00e-120	425.00
IUUC-Loc-052038	Lepisosteus oculatus	76.74	3.00e-95	340.00
IUUC-Laf-054126	Loxodonta africana	91.40	2.00e-126	444.00
IUUC-Mcc-055031	Macaca mulatta	97.45	2.00e-107	382.00
IUUC-Meu-056248	Macropus eugenii	87.71	4.00e-95	341.00
IUUC-Mga-059217	Meleagris gallopavo	86.70	2.00e-93	335.00
IUUC-Mmr-061581	Microcebus murinus	90.12	8.00e-104	369.00
IUUC-Mdo-062452	Monodelphis domestica	89.96	1.00e-123	435.00
IUUC-Mmu-063412	Mus musculus	90.32	1.00e-124	438.00
IUUC-Mpu-066479	Mustela putorius furo	88.89	5.00e-98	350.00
IUUC-Mlu-067586	Myotis lucifugus	76.87	1.00e-112	399.00
IUUC-Nle-069122	Nomascus leucogenys	99.28	5.00e-137	479.00
IUUC-Opr-070835	Ochotona princeps	84.55	8.00e-84	302.00
IUUC-Oan-073023	Ornithorhynchus anatinus	89.25	6.00e-121	426.00
IUUC-Ocu-073779	Oryctolagus cuniculus	85.00	8.00e-90	322.00
IUUC-Oin-079049	Oryza indica	70.49	5.00e-27	114.00
IUUC-Oni-082218	Oryza nivara	70.49	5.00e-27	114.00
IUUC-Ola-086891	Oryzias latipes	66.90	2.00e-96	345.00
IUUC-Olu-087851	Ostreococcus lucimarinus	69.23	2.00e-19	89.00
IUUC-Oga-087954	Otolemur garnettii	90.32	3.00e-124	437.00
IUUC-Oar-090006	Ovis aries	88.89	3.00e-121	427.00
IUUC-Ptr-090589	Pan troglodytes	99.64	1.00e-137	482.00
IUUC-Pan-091896	Papio anubis	97.87	2.00e-108	385.00
IUUC-Psi-093266	Pelodiscus sinensis	90.32	5.00e-124	436.00
IUUC-Pma-094265	Petromyzon marinus	75.34	2.00e-33	134.00
IUUC-Pop-099415	Populus trichocarpa	76.36	2.00e-25	109.00
IUUC-Pva-102753	Pteropus vampyrus	78.76	1.00e-85	310.00
IUUC-Rno-105964	Rattus norvegicus	88.03	9.00e-89	319.00
IUUC-Sha-107270	Sarcophilus harrisii	89.61	1.00e-122	432.00
IUUC-Sre-115124	Sporisorium reilianum	57.14	3.00e-21	97.10
IUUC-Tgu-116822	Taeniopygia guttata	90.32	5.00e-124	436.00
IUUC-Tre-121950	Trichoderma reesei	64.29	2.00e-19	91.30
IUUC-Tvi-122341	Trichoderma virens	62.50	5.00e-16	76.60
IUUC-Ttr-128672	Tursiops truncatus	88.51	5.00e-96	343.00
IUUC-Uma-129581	Ustilago maydis	57.14	3.00e-21	97.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence