iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-051791

Ensembl Protein ID

ENSLOCP00000017981.1

UniProt Accession

W5NBH2; W5NBH2_LEPOC

Genbank Protein ID

ENSLOCP00000017981

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01023721

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000014611.1	ENSLOCT00000018013.1	ENSLOCP00000017981.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	3.10e-14	52.8	457	499

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 8    rseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           r +p+SLqh+CR +I +c++++++   d LP+P++Lk++L++++y+
   Q: 457  RVHPFSLQHICRAVIASCTTYDGI---DVLPIPSALKEHLKEYHYK 499
           669*********************...****************985 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MSQSPEAEER GKEKERGARP KVRQSRSEER REGNGRKSGR GKKKGRPPQN PLPERPVSDG 60
FEYGELQGGR DPGDTGLPFQ ERCRWQDLTS AGTALQELGV DRPVAGTEEG EGEGGSAKLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGCAGT CCCCAGAAGC AGAGGAGCGG GGCAAGGAGA AGGAACGGGG CGCCCGACCC 60
AAAGTGAGAC AGAGCCGCTC GGAGGAGAGG AGGGAGGGCA ATGGCCGGAA GAGTGGAAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR022252--SOCS4/SOCS5_dom
IPR028420--SOCS5
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007259--P:JAK-STAT cascade
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-010732	Astyanax mexicanus	63.01	1.00e-161	562.00
IUUC-Bol-016597	Brassica oleracea	41.03	5.80e-02	32.70
IUUC-Dme-031965	Drosophila melanogaster	70.18	9.00e-71	261.00
IUUC-Ete-032972	Echinops telfairi	51.94	2.00e-90	325.00
IUUC-Gac-041931	Gasterosteus aculeatus	73.03	2.00e-153	535.00
IUUC-Lch-050636	Latimeria chalumnae	64.05	3.00e-159	554.00
IUUC-Ont-072537	Oreochromis niloticus	64.73	1.00e-172	599.00
IUUC-Pfo-097139	Poecilia formosa	63.67	5.00e-169	587.00
IUUC-Pop-098820	Populus trichocarpa	44.12	5.60e-02	32.00
IUUC-Vvi-131327	Vitis vinifera	45.95	3.10e-02	33.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence