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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-064320
Ensembl Protein ID ENSMUSP00000073584.6
UniProt Accession Q5F259; B9EKW8; Q6IR40; AN13B_MOUSE
Genbank Protein ID CAI52037.1; AAH71189.1; AAI51159.1
Protein Name Ankyrin repeat domain-containing protein 13B
Genbank Nucleotide ID AL607072; BC071189; BC151158
Gene Name Ankrd13b
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000037907.16 ENSMUST00000145934.7 ENSMUSP00000119633.1
ENSMUSG00000037907.16 ENSMUST00000037593.13 ENSMUSP00000073584.6
ENSMUSG00000037907.16 ENSMUST00000127291.1 ENSMUSP00000118247.1
ENSMUSG00000037907.16 ENSMUST00000092892.9 ENSMUSP00000090568.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
miRTarBasemicroRNATRANSFACRepTar
RAID2
Protein-protein Interaction
IIDMentha
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UIM 96.99 0.00e+00 1089.00 IUUC-Hsa-046090
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Mus musculus
Functional Description
(View)

Functional Description


     Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity).
 Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane (By similarity).
Protein Sequence
(Fasta)
MIPANASARK GPEGKYPLHY LVWHNRHREL EKEVRAGQVD IEQLDPRGRT PLHLATTLGH 60
LECARVLLAH GADVGRENRS GWTVLQEAVS TRDLELVQLV LRYRDYQRVV KRLAGIPMLL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064320|UBD,UIM|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACATGCCCGA GCCGCAGCCC CGCGAGCAGA CAGCTCCGGC CGTCCGCCCC GCGGCCCCGG 60
GCCCGGGCTC CCGCGCCGTC CCTCCCCGCG GGCCGGGCGC CGCGGCCCCG GCATGAGGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064320|UBD,UIM|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0040--ANK repeat
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0967--Endosome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR021832--ANKRD13
IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR003903--UIM_dom
PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50330--UIM
Pfam

PF12796--Ank_2
PF11904--GPCR_chapero_1
SMART

SM00248--ANK
SM00726--UIM
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005769--C:early endosome
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005770--C:late endosome
GO:0005886--C:plasma membrane
KEGG mmu:268445
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000665 Aegilops tauschii 29.59 5.00e-14 72.40
IUUC-Aml-002227 Ailuropoda melanoleuca 96.92 0.00e+00 992.00
IUUC-Atr-002910 Amborella trichopoda 32.43 1.00e-30 128.00
IUUC-Aca-004536 Anolis carolinensis 74.15 0.00e+00 819.00
IUUC-Aly-006347 Arabidopsis lyrata 27.81 9.00e-34 138.00
IUUC-Ath-007312 Arabidopsis thaliana 27.96 5.00e-37 149.00
IUUC-Ame-011280 Astyanax mexicanus 70.66 0.00e+00 790.00
IUUC-Bta-012633 Bos taurus 95.64 0.00e+00 1093.00
IUUC-Bdi-015044 Brachypodium distachyon 33.21 4.00e-27 116.00
IUUC-Bol-016226 Brassica oleracea 28.06 1.00e-34 141.00
IUUC-Bra-017598 Brassica rapa 29.76 3.00e-38 153.00
IUUC-Cja-019421 Callithrix jacchus 96.10 0.00e+00 818.00
IUUC-Cfa-020114 Canis familiaris 94.64 0.00e+00 1069.00
IUUC-Cpo-022470 Cavia porcellus 96.59 0.00e+00 1030.00
IUUC-Csa-023354 Chlorocebus sabaeus 96.97 0.00e+00 1082.00
IUUC-Dre-027443 Danio rerio 69.72 0.00e+00 791.00
IUUC-Dno-029392 Dasypus novemcinctus 93.48 0.00e+00 957.00
IUUC-Dor-030806 Dipodomys ordii 91.46 0.00e+00 773.00
IUUC-Eca-033903 Equus caballus 96.36 0.00e+00 983.00
IUUC-Eeu-034577 Erinaceus europaeus 95.76 0.00e+00 878.00
IUUC-Fca-035836 Felis catus 94.64 0.00e+00 1078.00
IUUC-Fal-037542 Ficedula albicollis 84.34 0.00e+00 982.00
IUUC-Gmo-039247 Gadus morhua 68.35 0.00e+00 790.00
IUUC-Gga-040451 Gallus gallus 88.69 0.00e+00 969.00
IUUC-Gac-041465 Gasterosteus aculeatus 68.17 0.00e+00 771.00
IUUC-Gma-043893 Glycine max 32.40 8.00e-38 151.00
IUUC-Ggo-044843 Gorilla gorilla 96.95 0.00e+00 1005.00
IUUC-Hsa-046090 Homo sapiens 96.97 0.00e+00 1083.00
IUUC-Hvu-047841 Hordeum vulgare 31.43 1.00e-30 128.00
IUUC-Itr-048446 Ictidomys tridecemlineatus 96.92 0.00e+00 1048.00
IUUC-Lch-049984 Latimeria chalumnae 81.56 0.00e+00 855.00
IUUC-Lpe-051217 Leersia perrieri 33.33 5.00e-27 116.00
IUUC-Laf-054198 Loxodonta africana 91.26 0.00e+00 1031.00
IUUC-Mcc-055437 Macaca mulatta 97.14 0.00e+00 1082.00
IUUC-Meu-056403 Macropus eugenii 87.50 0.00e+00 925.00
IUUC-Mtr-058522 Medicago truncatula 28.37 1.00e-32 134.00
IUUC-Mga-059949 Meleagris gallopavo 84.14 0.00e+00 833.00
IUUC-Mmr-061704 Microcebus murinus 96.63 0.00e+00 1082.00
IUUC-Mdo-062800 Monodelphis domestica 89.39 0.00e+00 1031.00
IUUC-Mac-065460 Musa acuminata 29.58 2.00e-38 153.00
IUUC-Mpu-065892 Mustela putorius furo 95.91 0.00e+00 1004.00
IUUC-Mlu-067964 Myotis lucifugus 81.21 0.00e+00 808.00
IUUC-Nle-069652 Nomascus leucogenys 90.66 0.00e+00 890.00
IUUC-Opr-071009 Ochotona princeps 89.45 0.00e+00 887.00
IUUC-Ont-072518 Oreochromis niloticus 71.53 0.00e+00 764.00
IUUC-Oan-072815 Ornithorhynchus anatinus 85.94 0.00e+00 810.00
IUUC-Ocu-074278 Oryctolagus cuniculus 98.44 0.00e+00 919.00
IUUC-Oba-075972 Oryza barthii 30.17 5.00e-26 112.00
IUUC-Obr-076237 Oryza brachyantha 30.62 6.00e-26 112.00
IUUC-Ogl-077611 Oryza glaberrima 31.55 1.00e-31 131.00
IUUC-Ogu-078651 Oryza glumaepatula 31.55 1.00e-31 131.00
IUUC-Oin-079479 Oryza indica 31.55 1.00e-31 131.00
IUUC-Olo-080761 Oryza longistaminata 30.17 5.00e-26 112.00
IUUC-Ome-081427 Oryza meridionalis 31.55 2.00e-31 130.00
IUUC-Oni-082794 Oryza nivara 31.55 1.00e-31 131.00
IUUC-Opu-084158 Oryza punctata 31.23 4.00e-31 129.00
IUUC-Oru-084489 Oryza rufipogon 31.55 1.00e-31 131.00
IUUC-Osa-085430 Oryza sativa 31.55 1.00e-31 131.00
IUUC-Ola-087114 Oryzias latipes 69.03 0.00e+00 791.00
IUUC-Oga-089031 Otolemur garnettii 96.63 0.00e+00 1093.00
IUUC-Oar-089561 Ovis aries 92.64 0.00e+00 1047.00
IUUC-Ptr-091401 Pan troglodytes 96.80 0.00e+00 1075.00
IUUC-Pan-092615 Papio anubis 96.98 0.00e+00 1085.00
IUUC-Ppa-096001 Physcomitrella patens 34.36 1.00e-28 121.00
IUUC-Pfo-096300 Poecilia formosa 65.94 0.00e+00 763.00
IUUC-Pab-098006 Pongo abelii 96.40 0.00e+00 997.00
IUUC-Pop-099831 Populus trichocarpa 28.71 7.00e-32 132.00
IUUC-Pca-101055 Procavia capensis 91.12 0.00e+00 1032.00
IUUC-Ppe-101713 Prunus persica 34.70 5.00e-34 139.00
IUUC-Pva-102501 Pteropus vampyrus 98.21 0.00e+00 914.00
IUUC-Rno-104986 Rattus norvegicus 98.48 0.00e+00 1093.00
IUUC-Smo-109402 Selaginella moellendorffii 35.06 8.00e-34 138.00
IUUC-Sit-110746 Setaria italica 34.17 3.00e-28 120.00
IUUC-Sly-111817 Solanum lycopersicum 30.22 3.00e-35 143.00
IUUC-Stu-112735 Solanum tuberosum 34.10 2.00e-30 127.00
IUUC-Sar-113707 Sorex araneus 93.53 0.00e+00 994.00
IUUC-Sbi-114285 Sorghum bicolor 31.33 3.00e-31 130.00
IUUC-Ssc-116209 Sus scrofa 95.17 0.00e+00 1015.00
IUUC-Tgu-117342 Taeniopygia guttata 85.23 0.00e+00 912.00
IUUC-Tru-117882 Takifugu rubripes 64.15 0.00e+00 760.00
IUUC-Tni-119972 Tetraodon nigroviridis 66.18 0.00e+00 691.00
IUUC-Tca-121256 Theobroma cacao 33.73 6.00e-34 139.00
IUUC-Tae-123916 Triticum aestivum 37.04 4.00e-19 90.10
IUUC-Tur-126871 Triticum urartu 31.22 2.00e-24 107.00
IUUC-Tbe-127904 Tupaia belangeri 95.27 0.00e+00 779.00
IUUC-Ttr-128724 Tursiops truncatus 97.27 0.00e+00 1056.00
IUUC-Vvi-131403 Vitis vinifera 29.29 3.00e-30 127.00
IUUC-Xtr-132340 Xenopus tropicalis 74.11 0.00e+00 771.00
IUUC-Xma-133401 Xiphophorus maculatus 69.95 0.00e+00 752.00
Created Date 25-Jun-2017

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