iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074627

Ensembl Protein ID

ENSOCUP00000008741.3

UniProt Accession

G1SYN9; G1SYN9_RABIT

Genbank Protein ID

ENSOCUP00000008741

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02040260

Gene Name

HDAC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000010141.3	ENSOCUT00000010143.3	ENSOCUP00000008741.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	78.39	0.00e+00	1829.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

METKSSGTRG PTGRREVGGG RRGRSLSSGP RLESGSGRIG RHRQQGRENR TRAEISPTMS 60
STGPESTTAR SRRSRHNPQS SPHDSSGTPK RSVKKGALPR CSPNLLEIKK KGKMKKLSQA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGCCTGAA GTCACGTTGG CCCTCGCGAG GCGTGCGGCC CTGAGGCACC ATCCCCGCTG 60
TGGGCGGGAC GTGGGCGGGC AGTAAGAGGG GGCAGGCCCA ATGGAAACGA AAAGTTCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0016235--C:aggresome
GO:0030424--C:axon
GO:0005901--C:caveola
GO:0031252--C:cell leading edge
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030286--C:dynein complex
GO:0000118--C:histone deacetylase complex
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0001047--F:core promoter binding
GO:0004407--F:histone deacetylase activity
GO:0042903--F:tubulin deacetylase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0070301--P:cellular response to hydrogen peroxide
GO:0071218--P:cellular response to misfolded protein
GO:0048668--P:collateral sprouting
GO:0060997--P:dendritic spine morphogenesis
GO:0070846--P:Hsp90 deacetylation
GO:0032418--P:lysosome localization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0051646--P:mitochondrion localization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0045861--P:negative regulation of proteolysis
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0034983--P:peptidyl-lysine deacetylation
GO:0070845--P:polyubiquitinated misfolded protein transport
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0010634--P:positive regulation of epithelial cell migration
GO:1901300--P:positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0010870--P:positive regulation of receptor biosynthetic process
GO:0009967--P:positive regulation of signal transduction
GO:0043241--P:protein complex disassembly
GO:0000209--P:protein polyubiquitination
GO:0070201--P:regulation of establishment of protein localization
GO:0045598--P:regulation of fat cell differentiation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0031647--P:regulation of protein stability
GO:0010469--P:regulation of receptor activity
GO:0070848--P:response to growth factor
GO:0009636--P:response to toxic substance
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	41.62	7.00e-72	265.00
IUUC-Aml-002087	Ailuropoda melanoleuca	80.72	0.00e+00	1847.00
IUUC-Atr-002745	Amborella trichopoda	43.13	3.00e-87	316.00
IUUC-Apl-003250	Anas platyrhynchos	44.58	6.00e-84	305.00
IUUC-Aca-004303	Anolis carolinensis	50.17	0.00e+00	1141.00
IUUC-Aly-006432	Arabidopsis lyrata	42.53	2.00e-80	293.00
IUUC-Ath-007355	Arabidopsis thaliana	42.75	1.00e-86	313.00
IUUC-Ago-007972	Ashbya gossypii	42.93	7.00e-85	308.00
IUUC-Acl-008187	Aspergillus clavatus	43.93	2.00e-86	313.00
IUUC-Afl-008399	Aspergillus flavus	47.03	8.00e-50	191.00
IUUC-Afu-008954	Aspergillus fumigatus	38.74	1.00e-77	283.00
IUUC-Ani-009142	Aspergillus nidulans	41.91	3.00e-79	289.00
IUUC-Ang-009522	Aspergillus niger	34.37	2.00e-48	187.00
IUUC-Aor-010069	Aspergillus oryzae	41.64	2.00e-77	283.00
IUUC-Ate-010291	Aspergillus terreus	43.04	4.00e-86	312.00
IUUC-Ame-010780	Astyanax mexicanus	51.41	0.00e+00	773.00
IUUC-Bta-013052	Bos taurus	75.86	0.00e+00	1657.00
IUUC-Bci-013789	Botrytis cinerea	40.85	5.00e-78	285.00
IUUC-Bdi-014007	Brachypodium distachyon	42.34	2.00e-86	313.00
IUUC-Bol-015468	Brassica oleracea	43.26	3.00e-83	302.00
IUUC-Bra-016680	Brassica rapa	45.03	1.00e-83	304.00
IUUC-Cel-018220	Caenorhabditis elegans	38.80	3.00e-150	525.00
IUUC-Cja-019473	Callithrix jacchus	74.98	0.00e+00	1704.00
IUUC-Cfa-020263	Canis familiaris	79.61	0.00e+00	1773.00
IUUC-Cpo-021691	Cavia porcellus	80.09	0.00e+00	1786.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	54.19	3.00e-56	211.00
IUUC-Csa-024223	Chlorocebus sabaeus	78.70	0.00e+00	1806.00
IUUC-Csv-026359	Ciona savignyi	49.18	6.00e-60	223.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	40.16	6.00e-79	288.00
IUUC-Cne-026978	Cryptococcus neoformans	44.97	3.00e-92	333.00
IUUC-Dre-028820	Danio rerio	57.88	0.00e+00	917.00
IUUC-Dno-029160	Dasypus novemcinctus	71.21	0.00e+00	1561.00
IUUC-Dor-030859	Dipodomys ordii	70.80	0.00e+00	1627.00
IUUC-Dse-031186	Dothistroma septosporum	41.10	2.00e-82	300.00
IUUC-Dme-031963	Drosophila melanogaster	44.62	0.00e+00	693.00
IUUC-Ete-032279	Echinops telfairi	66.75	4.00e-156	545.00
IUUC-Eca-033842	Equus caballus	80.00	0.00e+00	1832.00
IUUC-Eeu-034487	Erinaceus europaeus	75.51	9.00e-152	531.00
IUUC-Fca-036430	Felis catus	79.95	0.00e+00	1783.00
IUUC-Fox-038067	Fusarium oxysporum	41.19	4.00e-79	288.00
IUUC-Fso-038263	Fusarium solani	42.23	6.00e-82	298.00
IUUC-Gmo-038473	Gadus morhua	42.20	2.00e-76	280.00
IUUC-Ggr-040062	Gaeumannomyces graminis	41.88	8.00e-75	275.00
IUUC-Gga-040501	Gallus gallus	44.84	5.00e-84	306.00
IUUC-Gac-042335	Gasterosteus aculeatus	44.50	4.00e-83	303.00
IUUC-Gma-043738	Glycine max	48.79	6.00e-87	315.00
IUUC-Ggo-045022	Gorilla gorilla	78.20	0.00e+00	1783.00
IUUC-Hsa-046904	Homo sapiens	78.62	0.00e+00	1790.00
IUUC-Hvu-047285	Hordeum vulgare	45.23	7.00e-85	306.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	80.36	0.00e+00	1853.00
IUUC-Kpa-049281	Komagataella pastoris	41.03	6.00e-86	311.00
IUUC-Lch-050330	Latimeria chalumnae	46.22	0.00e+00	935.00
IUUC-Lpe-051214	Leersia perrieri	43.42	4.00e-87	315.00
IUUC-Loc-052231	Lepisosteus oculatus	44.78	6.00e-84	305.00
IUUC-Lma-053263	Leptosphaeria maculans	45.17	1.00e-92	334.00
IUUC-Laf-053386	Loxodonta africana	75.11	0.00e+00	1680.00
IUUC-Mcc-055530	Macaca mulatta	78.79	0.00e+00	1796.00
IUUC-Meu-056442	Macropus eugenii	67.39	0.00e+00	962.00
IUUC-Mor-057095	Magnaporthe oryzae	39.65	1.00e-83	304.00
IUUC-Mpo-057389	Magnaporthe poae	41.31	4.00e-74	272.00
IUUC-Mtr-058463	Medicago truncatula	44.72	7.00e-89	321.00
IUUC-Mla-059143	Melampsora laricipopulina	43.70	2.00e-84	306.00
IUUC-Mmr-060637	Microcebus murinus	78.93	0.00e+00	1869.00
IUUC-Mdo-062198	Monodelphis domestica	67.04	0.00e+00	1063.00
IUUC-Mmu-063346	Mus musculus	74.61	0.00e+00	1677.00
IUUC-Mac-064630	Musa acuminata	39.95	1.00e-84	307.00
IUUC-Mpu-065884	Mustela putorius furo	76.83	0.00e+00	1816.00
IUUC-Mlu-068117	Myotis lucifugus	78.74	0.00e+00	1755.00
IUUC-Nfi-068404	Neosartorya fischeri	43.15	4.00e-86	312.00
IUUC-Ncr-068672	Neurospora crassa	40.41	2.00e-79	290.00
IUUC-Nle-069868	Nomascus leucogenys	91.10	0.00e+00	727.00
IUUC-Opr-071074	Ochotona princeps	79.32	0.00e+00	1262.00
IUUC-Ont-072246	Oreochromis niloticus	45.37	0.00e+00	939.00
IUUC-Oan-072911	Ornithorhynchus anatinus	68.53	1.00e-105	377.00
IUUC-Oba-075489	Oryza barthii	45.23	8.00e-85	307.00
IUUC-Obr-076150	Oryza brachyantha	43.89	9.00e-87	314.00
IUUC-Ogl-077437	Oryza glaberrima	42.62	2.00e-85	310.00
IUUC-Ogu-078370	Oryza glumaepatula	42.90	4.00e-86	312.00
IUUC-Oin-079210	Oryza indica	42.90	3.00e-86	312.00
IUUC-Olo-080971	Oryza longistaminata	46.24	2.00e-74	273.00
IUUC-Oni-082031	Oryza nivara	42.90	8.00e-86	311.00
IUUC-Opu-083471	Oryza punctata	44.92	7.00e-85	308.00
IUUC-Oru-084755	Oryza rufipogon	42.90	4.00e-86	312.00
IUUC-Osa-085447	Oryza sativa	42.90	4.00e-86	312.00
IUUC-Ola-087031	Oryzias latipes	44.09	3.00e-81	296.00
IUUC-Oga-089155	Otolemur garnettii	77.33	0.00e+00	1798.00
IUUC-Oar-089620	Ovis aries	75.83	0.00e+00	1679.00
IUUC-Ptr-090812	Pan troglodytes	87.86	0.00e+00	1240.00
IUUC-Pan-092340	Papio anubis	78.62	0.00e+00	1791.00
IUUC-Psi-093734	Pelodiscus sinensis	44.70	2.00e-83	303.00
IUUC-Pma-094386	Petromyzon marinus	52.99	0.00e+00	799.00
IUUC-Pno-095131	Phaeosphaeria nodorum	47.54	1.00e-77	283.00
IUUC-Ppa-095550	Physcomitrella patens	45.31	2.00e-90	327.00
IUUC-Pfo-096110	Poecilia formosa	52.57	0.00e+00	723.00
IUUC-Pab-098422	Pongo abelii	77.36	0.00e+00	1753.00
IUUC-Pop-099174	Populus trichocarpa	42.31	4.00e-81	296.00
IUUC-Pca-100833	Procavia capensis	72.97	0.00e+00	1528.00
IUUC-Ppe-101644	Prunus persica	43.33	2.00e-87	316.00
IUUC-Pva-102410	Pteropus vampyrus	72.88	0.00e+00	1587.00
IUUC-Ptt-103841	Puccinia triticina	39.54	1.00e-82	300.00
IUUC-Pte-104383	Pyrenophora teres	43.47	1.00e-87	317.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	43.47	2.00e-87	316.00
IUUC-Rno-105131	Rattus norvegicus	74.98	0.00e+00	1709.00
IUUC-Sce-106274	Saccharomyces cerevisiae	40.41	9.00e-81	294.00
IUUC-Sha-106661	Sarcophilus harrisii	54.91	0.00e+00	808.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	42.66	2.00e-89	323.00
IUUC-Spo-108300	Schizosaccharomyces pombe	46.03	2.00e-89	323.00
IUUC-Smo-109615	Selaginella moellendorffii	48.94	5.00e-88	318.00
IUUC-Sit-110160	Setaria italica	42.90	2.00e-81	296.00
IUUC-Sly-111164	Solanum lycopersicum	39.83	2.00e-82	300.00
IUUC-Stu-112685	Solanum tuberosum	40.81	4.00e-75	275.00
IUUC-Sar-113692	Sorex araneus	64.94	0.00e+00	736.00
IUUC-Sbi-114301	Sorghum bicolor	43.21	2.00e-81	296.00
IUUC-Sre-115013	Sporisorium reilianum	42.12	5.00e-80	292.00
IUUC-Ssc-115724	Sus scrofa	77.42	0.00e+00	1650.00
IUUC-Tgu-116605	Taeniopygia guttata	53.19	2.00e-110	392.00
IUUC-Tru-117614	Takifugu rubripes	56.48	0.00e+00	852.00
IUUC-Tsy-118807	Tarsius syrichta	66.93	0.00e+00	862.00
IUUC-Tni-119809	Tetraodon nigroviridis	55.76	0.00e+00	795.00
IUUC-Tca-121312	Theobroma cacao	46.25	2.00e-85	310.00
IUUC-Tre-121930	Trichoderma reesei	40.60	7.00e-81	295.00
IUUC-Tvi-122373	Trichoderma virens	40.70	2.00e-81	297.00
IUUC-Tae-123064	Triticum aestivum	41.11	1.00e-79	290.00
IUUC-Tme-127027	Tuber melanosporum	43.05	6.00e-73	268.00
IUUC-Tbe-127675	Tupaia belangeri	55.38	1.00e-95	344.00
IUUC-Ttr-128411	Tursiops truncatus	77.38	0.00e+00	1751.00
IUUC-Uma-129408	Ustilago maydis	46.43	1.00e-75	277.00
IUUC-Vda-129994	Verticillium dahliae	39.33	2.00e-74	273.00
IUUC-Vpa-130525	Vicugna pacos	80.85	2.00e-62	234.00
IUUC-Vvi-131038	Vitis vinifera	42.46	2.00e-86	313.00
IUUC-Xtr-132618	Xenopus tropicalis	57.98	0.00e+00	958.00
IUUC-Xma-133730	Xiphophorus maculatus	48.92	0.00e+00	706.00
IUUC-Yli-134680	Yarrowia lipolytica	41.90	1.00e-84	307.00
IUUC-Zma-135110	Zea mays	42.78	3.00e-82	299.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence