iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062516

Ensembl Protein ID

ENSMODP00000009423.3

UniProt Accession

F7CPB8; F7CPB8_MONDO

Protein Name

Uncharacterized protein

Gene Name

MAP3K10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000007594.3	ENSMODT00000009608.3	ENSMODP00000009423.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.90e-15	56.7	34	89

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlvieke...eqdegWlkgvkelegkrGlfPenFve 60
            + +dyea+ ++eLtl++Gd+v+v++++   + degW+ g+  l g+ G+fP+n+v+
   Q: 34   TAVFDYEAAGEEELTLRRGDQVRVLSQDwavSGDEGWWTGQ-LLGGRVGVFPSNYVV 89
           689**********************65533489*******7.9************96 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MEEEEDGGEG PALRGTEEWG LGPDAPAAAE PLWTAVFDYE AAGEEELTLR RGDQVRVLSQ 60
DWAVSGDEGW WTGQLLGGRV GVFPSNYVVA PGVPAPAPSG LPLPREIPFG ELQLEEIIGV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGAGG AGGAGGACGG TGGGGAGGGC CCAGCCCTGC GGGGGACCGA AGAGTGGGGC 60
CTGGGGCCCG ACGCCCCTGC AGCCGCCGAG CCCCTGTGGA CCGCCGTGTT TGATTATGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR015785--MAP3K10
IPR016231--MLK1/MLK2/MLK4
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00220--S_TKc
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004706--F:JUN kinase kinase kinase activity
GO:0003714--F:transcription corepressor activity
GO:0007257--P:activation of JUN kinase activity
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043065--P:positive regulation of apoptotic process
GO:0007224--P:smoothened signaling pathway

KEGG

mdo:100017495

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001187	Ailuropoda melanoleuca	83.49	0.00e+00	852.00
IUUC-Aca-004768	Anolis carolinensis	74.92	0.00e+00	806.00
IUUC-Ath-006581	Arabidopsis thaliana	32.03	4.00e-28	120.00
IUUC-Bra-016997	Brassica rapa	32.62	9.00e-28	119.00
IUUC-Cja-019696	Callithrix jacchus	70.05	0.00e+00	933.00
IUUC-Cpo-021993	Cavia porcellus	85.36	0.00e+00	864.00
IUUC-Csa-024243	Chlorocebus sabaeus	84.52	0.00e+00	830.00
IUUC-Cho-024961	Choloepus hoffmanni	84.83	2.00e-99	356.00
IUUC-Dre-028573	Danio rerio	70.89	0.00e+00	761.00
IUUC-Dno-029095	Dasypus novemcinctus	73.42	0.00e+00	925.00
IUUC-Fca-036250	Felis catus	83.55	0.00e+00	828.00
IUUC-Gmo-038497	Gadus morhua	71.40	0.00e+00	749.00
IUUC-Gac-042509	Gasterosteus aculeatus	71.29	0.00e+00	738.00
IUUC-Gma-043168	Glycine max	36.04	9.00e-26	112.00
IUUC-Ggo-045471	Gorilla gorilla	79.74	0.00e+00	776.00
IUUC-Hsa-046936	Homo sapiens	75.29	0.00e+00	979.00
IUUC-Itr-048231	Ictidomys tridecemlineatus	84.38	0.00e+00	840.00
IUUC-Lpe-051668	Leersia perrieri	33.93	2.00e-25	110.00
IUUC-Loc-052286	Lepisosteus oculatus	68.03	0.00e+00	753.00
IUUC-Mcc-055733	Macaca mulatta	73.52	0.00e+00	991.00
IUUC-Meu-056131	Macropus eugenii	96.47	2.00e-149	523.00
IUUC-Mtr-058580	Medicago truncatula	35.71	3.00e-25	110.00
IUUC-Mmu-064082	Mus musculus	74.69	0.00e+00	1049.00
IUUC-Mac-065156	Musa acuminata	31.52	8.00e-27	115.00
IUUC-Mpu-065934	Mustela putorius furo	84.22	0.00e+00	847.00
IUUC-Mlu-068137	Myotis lucifugus	68.03	0.00e+00	951.00
IUUC-Opr-070869	Ochotona princeps	83.77	6.00e-178	617.00
IUUC-Ont-072492	Oreochromis niloticus	72.12	0.00e+00	769.00
IUUC-Ocu-074350	Oryctolagus cuniculus	73.38	0.00e+00	965.00
IUUC-Ola-087224	Oryzias latipes	56.97	0.00e+00	827.00
IUUC-Oga-088351	Otolemur garnettii	75.13	0.00e+00	1019.00
IUUC-Ptr-091607	Pan troglodytes	75.18	0.00e+00	980.00
IUUC-Pan-092403	Papio anubis	83.74	0.00e+00	807.00
IUUC-Pfo-096104	Poecilia formosa	70.90	0.00e+00	754.00
IUUC-Pab-098396	Pongo abelii	83.71	0.00e+00	808.00
IUUC-Pop-100071	Populus trichocarpa	32.73	9.00e-26	112.00
IUUC-Rno-105688	Rattus norvegicus	75.47	0.00e+00	1060.00
IUUC-Smo-109113	Selaginella moellendorffii	32.48	5.00e-26	111.00
IUUC-Sit-110451	Setaria italica	32.73	2.00e-26	114.00
IUUC-Ssc-115332	Sus scrofa	84.34	0.00e+00	856.00
IUUC-Tru-117692	Takifugu rubripes	62.47	0.00e+00	773.00
IUUC-Tsy-119412	Tarsius syrichta	79.72	2.00e-56	213.00
IUUC-Tni-120689	Tetraodon nigroviridis	61.20	0.00e+00	754.00
IUUC-Tur-126322	Triticum urartu	32.04	3.00e-26	113.00
IUUC-Ttr-128550	Tursiops truncatus	75.00	0.00e+00	1026.00
IUUC-Xtr-132108	Xenopus tropicalis	62.64	0.00e+00	964.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence