iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afl-008736

Ensembl Protein ID

EED48643

UniProt Accession

B8NP83; B8NP83_ASPFN

Genbank Protein ID

EED48643.1

Protein Name

Ubiquitin-protein ligase Ufd4, putative

Genbank Nucleotide ID

EQ963481

Gene Name

AFLA_128660

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AFLA_128660	EED48643	EED48643

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.30e-79	266.7	1455	1826

Active Site

Position(s)	Description	Evidence
1793	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 6    kkrlevefvgEegldlgGvtreflallskelqnpdlglflysen.dketlqpnpdsglknp............ehlklFeflGrllgkalqdgrlldlp 91
            ++leve+ +E g++l G+t+ef++ +ske+ +++l++++ ++  d e++   +   +  p            ++l lF+ lG++++ ++ d+r++d+ 
   Q: 1455 PSVLEVEYFEEVGTGL-GPTLEFYSTVSKEFSKKKLKIWRENDCnDAEEFAFGKRGLFPAPmseqyaasesgkKQLHLFKVLGKFVARSMLDSRIIDVS 1552
           5789************.**********************55554377777777777766668888999******************************* PP
   S: 92   lsksfykll...lgkklsledleevdpelykslkeikenaes........................dieelgldltfsvseeilgetkeeeLkpgGeni 163
           ++++f++     +++  sl  +++vd++l++sl  +k+ a++                         ++ ++l l f+     l+ + + eL+ +G+n+
   Q: 1553 FNPAFFRIAdssFSVAPSLGTVKAVDQDLANSLLLLKRFANAkaevenkalseaqtrqallnvevdGVKVEDLSLDFT-----LPGYPSIELIKDGSNV 1646
           ******876444444899*******************98844455555566666666666666555344444444444.....89************** PP
   S: 164  pVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseer 261
           pVt+eN + Yv++vv+++l +g+++qveafreGf++v+p + l+ Ft+ el +l     e++++e+l + +k ++g++ ds+ +++++++++e+++++r
   Q: 1647 PVTIENVDLYVERVVDMTLSSGVQRQVEAFREGFSQVFPYSALRTFTPAELVMLFGRAeEDWSIETLMDSIKADHGFNMDSRSVRNLLQTMSELDAQQR 1745
           ***************************************************988777689*************************************** PP
   S: 262  kafLqFvTgssrlPlgGfaelkprlfvirk.....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFels 336
           ++fLqFvTgs++lP+gGf++l p ++v+ +     ++ dd lPs++TC+nyLkLP+Yss ++l+ +L +Ai+e+  +F+ls
   Q: 1746 RDFLQFVTGSPKLPIGGFKSLTPIFTVVCRpseppYTPDDYLPSVMTCVNYLKLPDYSSLDVLRTRLSVAIQEGqGAFHLS 1826
           ************************999988999*99999***********************************8899985 PP

Organism

Aspergillus flavus

Protein Sequence
(Fasta)

MARTRPNLHR QDPLEDSSTG APATAARITR SAARLAAEPP PPATSGPSPA NPAAGSAPNR 60
KRKVPSRSDR SVEAPGQPNP PSPPRRAKKQ RRAASPQPAA ASAAPRRGTR NRPAMSQSGP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGACCACTGC TTTTATCCCA GTTCTTGTCT GGTACTCATC ACTAATTCAT TCAGATACTT 60
GCTTTCCTTT TACTGTGTAT ATCTTTATTC CTTCCTCGTT CTCTGTTCTA ACTGTTGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

afv:AFLA_128660

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000060	Aegilops tauschii	35.68	6.00e-113	400.00
IUUC-Aml-001502	Ailuropoda melanoleuca	35.40	4.00e-113	401.00
IUUC-Atr-002821	Amborella trichopoda	36.15	1.00e-110	393.00
IUUC-Apl-003531	Anas platyrhynchos	33.03	2.00e-102	365.00
IUUC-Aca-004521	Anolis carolinensis	33.33	8.00e-34	138.00
IUUC-Aly-005962	Arabidopsis lyrata	41.52	5.00e-114	404.00
IUUC-Ath-006636	Arabidopsis thaliana	41.52	8.00e-115	407.00
IUUC-Ago-007875	Ashbya gossypii	41.59	2.00e-125	442.00
IUUC-Acl-008242	Aspergillus clavatus	78.87	0.00e+00	2518.00
IUUC-Afu-008812	Aspergillus fumigatus	77.22	0.00e+00	2474.00
IUUC-Ani-009407	Aspergillus nidulans	76.59	0.00e+00	1452.00
IUUC-Ang-009763	Aspergillus niger	81.62	0.00e+00	1520.00
IUUC-Aor-009941	Aspergillus oryzae	100.00	0.00e+00	1533.00
IUUC-Ate-010459	Aspergillus terreus	79.87	0.00e+00	2462.00
IUUC-Ame-011761	Astyanax mexicanus	37.39	7.00e-120	424.00
IUUC-Bgr-012265	Blumeria graminis	53.35	0.00e+00	1726.00
IUUC-Bta-013070	Bos taurus	35.55	5.00e-113	401.00
IUUC-Bci-013890	Botrytis cinerea	59.30	0.00e+00	1110.00
IUUC-Bdi-014046	Brachypodium distachyon	36.21	2.00e-110	392.00
IUUC-Bol-015942	Brassica oleracea	40.76	7.00e-112	397.00
IUUC-Bra-016849	Brassica rapa	39.83	1.00e-111	396.00
IUUC-Cel-018153	Caenorhabditis elegans	34.19	3.00e-79	289.00
IUUC-Cja-019046	Callithrix jacchus	35.40	4.00e-113	402.00
IUUC-Cfa-020521	Canis familiaris	35.55	8.00e-114	404.00
IUUC-Cpo-021639	Cavia porcellus	35.48	3.00e-113	402.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	40.00	2.00e-88	317.00
IUUC-Csa-023231	Chlorocebus sabaeus	35.40	5.00e-113	401.00
IUUC-Cho-024380	Choloepus hoffmanni	41.58	4.00e-90	325.00
IUUC-Cin-025482	Ciona intestinalis	37.38	1.00e-98	351.00
IUUC-Csv-026121	Ciona savignyi	33.97	3.00e-97	348.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	64.29	0.00e+00	892.00
IUUC-Cne-026857	Cryptococcus neoformans	45.06	1.00e-155	543.00
IUUC-Cme-027226	Cyanidioschyzon merolae	36.75	1.00e-80	293.00
IUUC-Dre-028174	Danio rerio	37.33	9.00e-120	424.00
IUUC-Dno-029954	Dasypus novemcinctus	32.92	1.00e-33	138.00
IUUC-Dor-030939	Dipodomys ordii	31.62	2.00e-91	329.00
IUUC-Dse-031444	Dothistroma septosporum	65.60	0.00e+00	918.00
IUUC-Dme-031739	Drosophila melanogaster	31.65	7.00e-82	298.00
IUUC-Ete-032345	Echinops telfairi	31.21	3.00e-81	295.00
IUUC-Eca-033229	Equus caballus	35.91	3.00e-112	399.00
IUUC-Eeu-035205	Erinaceus europaeus	35.63	2.00e-112	399.00
IUUC-Fca-036444	Felis catus	35.93	1.00e-112	400.00
IUUC-Fal-037131	Ficedula albicollis	35.10	1.00e-112	400.00
IUUC-Fox-038035	Fusarium oxysporum	61.49	0.00e+00	842.00
IUUC-Fso-038320	Fusarium solani	63.03	0.00e+00	888.00
IUUC-Gmo-039497	Gadus morhua	36.79	2.00e-118	419.00
IUUC-Ggr-040057	Gaeumannomyces graminis	62.33	0.00e+00	865.00
IUUC-Gga-041021	Gallus gallus	34.90	1.00e-112	400.00
IUUC-Gac-042474	Gasterosteus aculeatus	37.22	7.00e-119	421.00
IUUC-Gma-043060	Glycine max	37.19	1.00e-112	400.00
IUUC-Ggo-044855	Gorilla gorilla	35.40	4.00e-113	401.00
IUUC-Hsa-046147	Homo sapiens	35.40	6.00e-113	401.00
IUUC-Hvu-047775	Hordeum vulgare	36.85	2.00e-109	389.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	35.40	1.00e-112	400.00
IUUC-Kpa-049098	Komagataella pastoris	44.77	5.00e-128	451.00
IUUC-Lch-049818	Latimeria chalumnae	35.84	2.00e-113	402.00
IUUC-Lpe-051017	Leersia perrieri	36.27	1.00e-107	383.00
IUUC-Loc-051777	Lepisosteus oculatus	37.22	1.00e-120	426.00
IUUC-Lma-052990	Leptosphaeria maculans	66.49	0.00e+00	919.00
IUUC-Laf-053727	Loxodonta africana	35.60	3.00e-113	402.00
IUUC-Mcc-055799	Macaca mulatta	35.40	6.00e-113	401.00
IUUC-Meu-056065	Macropus eugenii	32.55	2.00e-86	313.00
IUUC-Mor-057054	Magnaporthe oryzae	61.19	0.00e+00	859.00
IUUC-Mpo-057417	Magnaporthe poae	62.89	0.00e+00	880.00
IUUC-Mtr-057849	Medicago truncatula	41.37	9.00e-114	404.00
IUUC-Mla-058870	Melampsora laricipopulina	48.56	5.00e-152	530.00
IUUC-Mga-059580	Meleagris gallopavo	31.62	5.00e-60	225.00
IUUC-Mvi-060507	Microbotryum violaceum	46.89	2.00e-169	589.00
IUUC-Mmr-060816	Microcebus murinus	35.25	9.00e-112	397.00
IUUC-Mdo-062866	Monodelphis domestica	32.83	1.00e-87	317.00
IUUC-Mmu-063906	Mus musculus	35.40	1.00e-112	400.00
IUUC-Mac-064675	Musa acuminata	37.29	2.00e-111	394.00
IUUC-Mpu-066199	Mustela putorius furo	35.40	4.00e-113	401.00
IUUC-Mlu-067110	Myotis lucifugus	35.40	3.00e-112	398.00
IUUC-Nfi-068482	Neosartorya fischeri	77.94	0.00e+00	2474.00
IUUC-Ncr-068906	Neurospora crassa	62.59	0.00e+00	876.00
IUUC-Nle-069410	Nomascus leucogenys	35.40	5.00e-113	401.00
IUUC-Opr-070401	Ochotona princeps	40.87	1.00e-52	201.00
IUUC-Ont-072100	Oreochromis niloticus	37.03	1.00e-119	423.00
IUUC-Oan-073121	Ornithorhynchus anatinus	34.90	6.00e-111	394.00
IUUC-Ocu-074623	Oryctolagus cuniculus	35.40	1.00e-112	400.00
IUUC-Oba-075380	Oryza barthii	35.38	3.00e-101	362.00
IUUC-Obr-076915	Oryza brachyantha	35.64	6.00e-106	377.00
IUUC-Ogl-077055	Oryza glaberrima	36.20	2.00e-105	376.00
IUUC-Ogu-078892	Oryza glumaepatula	35.08	3.00e-101	361.00
IUUC-Oin-079256	Oryza indica	36.18	6.00e-105	374.00
IUUC-Olo-080343	Oryza longistaminata	35.89	8.00e-105	374.00
IUUC-Ome-081422	Oryza meridionalis	35.89	1.00e-104	373.00
IUUC-Oni-083047	Oryza nivara	35.08	2.00e-102	365.00
IUUC-Opu-083641	Oryza punctata	34.77	6.00e-100	357.00
IUUC-Oru-084439	Oryza rufipogon	35.08	4.00e-101	361.00
IUUC-Osa-085972	Oryza sativa	36.20	6.00e-105	373.00
IUUC-Ola-087173	Oryzias latipes	36.64	8.00e-118	417.00
IUUC-Olu-087871	Ostreococcus lucimarinus	40.59	6.00e-102	362.00
IUUC-Oga-087908	Otolemur garnettii	35.25	4.00e-112	398.00
IUUC-Oar-090277	Ovis aries	35.55	6.00e-113	401.00
IUUC-Ptr-091543	Pan troglodytes	35.40	6.00e-113	401.00
IUUC-Pan-092243	Papio anubis	35.40	5.00e-113	401.00
IUUC-Psi-093150	Pelodiscus sinensis	35.05	1.00e-112	400.00
IUUC-Pno-094891	Phaeosphaeria nodorum	57.35	0.00e+00	1088.00
IUUC-Ppa-095181	Physcomitrella patens	43.87	6.00e-106	376.00
IUUC-Pfo-096267	Poecilia formosa	36.49	1.00e-116	413.00
IUUC-Pab-098072	Pongo abelii	35.40	5.00e-113	401.00
IUUC-Pop-099190	Populus trichocarpa	36.12	2.00e-112	399.00
IUUC-Pca-100311	Procavia capensis	35.55	9.00e-113	400.00
IUUC-Ppe-101284	Prunus persica	41.03	1.00e-113	403.00
IUUC-Pva-102215	Pteropus vampyrus	36.26	2.00e-97	349.00
IUUC-Pgr-103694	Puccinia graminis	47.22	3.00e-163	568.00
IUUC-Ptt-103916	Puccinia triticina	46.35	5.00e-155	541.00
IUUC-Pte-104346	Pyrenophora teres	59.73	0.00e+00	1167.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	59.77	0.00e+00	1159.00
IUUC-Rno-105315	Rattus norvegicus	35.40	9.00e-113	400.00
IUUC-Sce-106273	Saccharomyces cerevisiae	41.19	6.00e-115	407.00
IUUC-Sha-106835	Sarcophilus harrisii	35.40	2.00e-112	399.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	44.15	6.00e-144	503.00
IUUC-Spo-108081	Schizosaccharomyces pombe	44.99	9.00e-139	486.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	60.30	0.00e+00	1102.00
IUUC-Smo-109590	Selaginella moellendorffii	41.85	5.00e-106	377.00
IUUC-Sit-110717	Setaria italica	34.67	9.00e-109	387.00
IUUC-Sly-111557	Solanum lycopersicum	37.10	4.00e-116	411.00
IUUC-Stu-112896	Solanum tuberosum	36.95	1.00e-105	375.00
IUUC-Sar-113224	Sorex araneus	41.82	8.00e-83	301.00
IUUC-Sbi-114313	Sorghum bicolor	37.03	3.00e-115	408.00
IUUC-Sre-114993	Sporisorium reilianum	44.40	3.00e-163	568.00
IUUC-Ssc-115535	Sus scrofa	32.58	4.00e-91	328.00
IUUC-Tgu-117493	Taeniopygia guttata	31.62	4.00e-60	225.00
IUUC-Tru-118669	Takifugu rubripes	37.61	6.00e-119	421.00
IUUC-Tsy-119373	Tarsius syrichta	29.63	1.00e-71	264.00
IUUC-Tni-120049	Tetraodon nigroviridis	35.73	2.00e-85	307.00
IUUC-Tca-121779	Theobroma cacao	35.16	1.00e-108	386.00
IUUC-Tre-122195	Trichoderma reesei	60.03	0.00e+00	856.00
IUUC-Tvi-122650	Trichoderma virens	54.06	0.00e+00	1052.00
IUUC-Tae-123120	Triticum aestivum	35.40	6.00e-113	400.00
IUUC-Tur-126295	Triticum urartu	36.85	9.00e-111	393.00
IUUC-Tme-126964	Tuber melanosporum	66.57	0.00e+00	890.00
IUUC-Tbe-128149	Tupaia belangeri	38.15	5.00e-66	245.00
IUUC-Ttr-128165	Tursiops truncatus	35.90	6.00e-113	401.00
IUUC-Uma-129365	Ustilago maydis	45.92	2.00e-151	529.00
IUUC-Vda-129725	Verticillium dahliae	65.86	0.00e+00	806.00
IUUC-Vpa-130678	Vicugna pacos	35.85	5.00e-113	401.00
IUUC-Vvi-131147	Vitis vinifera	36.51	2.00e-112	399.00
IUUC-Xtr-132636	Xenopus tropicalis	36.09	2.00e-111	395.00
IUUC-Xma-133458	Xiphophorus maculatus	36.79	3.00e-119	422.00
IUUC-Yli-134481	Yarrowia lipolytica	46.50	7.00e-157	546.00
IUUC-Zma-135657	Zea mays	36.14	1.00e-110	393.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence