iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000003825.1	ENSAMET00000004214.1	ENSAMEP00000004050.1
ENSAMEG00000003825.1	ENSAMET00000004223.1	ENSAMEP00000004059.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	4.60e-10	39.4	541	578
ULD/UDP/UBQ/UBQ_PIM	4.70e-25	87.4	31	104

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 541  FQQQLEQLSAMGFlNREANLQALIATGGDINAAIERLL 578
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           mk+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tLs++gi+dg +vhlv+k+++
   Q: 31   MKVTVKTPKEKE-EFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQN 104
           99**********.***********************************************************987 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

XGGPPSSQDS AAAAEGAGAP AAAASAEPKI MKVTVKTPKE KEEFAVPENS SVQQFKEEIS 60
KRFKSHTDQL VLIFAGKILK DQDTLSQHGI HDGLTVHLVI KTQNRPQDHS AQQTNTSGSN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGGGAGAGG GAAAGAAAGG CAAGGAGGAG GAGCGGCGGC GGCTGCGGAT GTCGCTGCGA 60
CCGAGCGGCG TCTGAACACA CGGTGGCTGC GGAGCGCCCG ACCCGGGCCT GCGCCGGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0016235--C:aggresome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0035973--P:aggrephagy
GO:0000045--P:autophagosome assembly
GO:0097352--P:autophagosome maturation
GO:0071456--P:cellular response to hypoxia
GO:1901340--P:negative regulation of store-operated calcium channel activity
GO:0034140--P:negative regulation of toll-like receptor 3 signaling pathway
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0031398--P:positive regulation of protein ubiquitination
GO:1902175--P:regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000864	Aegilops tauschii	49.65	1.00e-37	151.00
IUUC-Atr-002470	Amborella trichopoda	40.29	2.00e-43	170.00
IUUC-Apl-003241	Anas platyrhynchos	83.77	0.00e+00	719.00
IUUC-Aca-004511	Anolis carolinensis	79.93	0.00e+00	720.00
IUUC-Aly-005419	Arabidopsis lyrata	37.50	3.00e-51	196.00
IUUC-Ath-007271	Arabidopsis thaliana	35.24	1.00e-49	190.00
IUUC-Ago-007963	Ashbya gossypii	37.68	8.00e-09	54.30
IUUC-Ani-009418	Aspergillus nidulans	25.58	1.00e-08	54.30
IUUC-Bta-013048	Bos taurus	96.21	0.00e+00	821.00
IUUC-Bol-015326	Brassica oleracea	32.57	2.00e-44	173.00
IUUC-Bra-018014	Brassica rapa	38.06	3.00e-40	159.00
IUUC-Cel-018631	Caenorhabditis elegans	38.73	3.00e-66	245.00
IUUC-Cja-019976	Callithrix jacchus	95.86	0.00e+00	831.00
IUUC-Cfa-020092	Canis familiaris	99.10	0.00e+00	841.00
IUUC-Cpo-022388	Cavia porcellus	94.05	0.00e+00	812.00
IUUC-Csa-024087	Chlorocebus sabaeus	95.99	0.00e+00	832.00
IUUC-Cho-024834	Choloepus hoffmanni	95.98	0.00e+00	841.00
IUUC-Cin-025136	Ciona intestinalis	50.55	1.00e-112	400.00
IUUC-Csv-026009	Ciona savignyi	53.16	1.00e-98	353.00
IUUC-Cne-026833	Cryptococcus neoformans	27.04	3.00e-13	69.30
IUUC-Cme-027155	Cyanidioschyzon merolae	57.55	2.00e-34	140.00
IUUC-Dno-028970	Dasypus novemcinctus	75.75	0.00e+00	636.00
IUUC-Dor-030519	Dipodomys ordii	92.99	0.00e+00	794.00
IUUC-Dse-031421	Dothistroma septosporum	27.49	1.00e-12	68.20
IUUC-Dme-032013	Drosophila melanogaster	46.47	2.00e-110	392.00
IUUC-Ete-032273	Echinops telfairi	94.33	0.00e+00	808.00
IUUC-Eca-033667	Equus caballus	96.05	0.00e+00	825.00
IUUC-Eeu-034865	Erinaceus europaeus	70.47	4.00e-158	551.00
IUUC-Fca-036179	Felis catus	95.50	0.00e+00	793.00
IUUC-Fal-037642	Ficedula albicollis	83.01	0.00e+00	755.00
IUUC-Gga-041264	Gallus gallus	84.77	0.00e+00	809.00
IUUC-Gac-041826	Gasterosteus aculeatus	64.91	3.00e-135	475.00
IUUC-Gma-042681	Glycine max	36.18	5.00e-36	145.00
IUUC-Ggo-044969	Gorilla gorilla	96.04	0.00e+00	811.00
IUUC-Hsa-046669	Homo sapiens	96.22	0.00e+00	844.00
IUUC-Itr-048337	Ictidomys tridecemlineatus	94.60	0.00e+00	668.00
IUUC-Lch-050192	Latimeria chalumnae	77.45	0.00e+00	677.00
IUUC-Lpe-051401	Leersia perrieri	36.09	2.00e-35	143.00
IUUC-Loc-052846	Lepisosteus oculatus	76.88	0.00e+00	672.00
IUUC-Lma-053152	Leptosphaeria maculans	30.55	3.00e-12	66.60
IUUC-Laf-054278	Loxodonta africana	94.77	0.00e+00	792.00
IUUC-Mcc-055680	Macaca mulatta	96.40	0.00e+00	844.00
IUUC-Meu-056207	Macropus eugenii	75.60	5.00e-172	597.00
IUUC-Mtr-058674	Medicago truncatula	37.80	2.00e-38	153.00
IUUC-Mga-059894	Meleagris gallopavo	82.85	0.00e+00	631.00
IUUC-Mmr-061094	Microcebus murinus	96.22	0.00e+00	819.00
IUUC-Mdo-062728	Monodelphis domestica	88.10	0.00e+00	768.00
IUUC-Mmu-064088	Mus musculus	84.96	0.00e+00	820.00
IUUC-Mac-065526	Musa acuminata	38.78	3.00e-45	176.00
IUUC-Mpu-066282	Mustela putorius furo	94.24	0.00e+00	804.00
IUUC-Mlu-068158	Myotis lucifugus	95.68	0.00e+00	800.00
IUUC-Nle-069321	Nomascus leucogenys	96.04	0.00e+00	844.00
IUUC-Opr-071098	Ochotona princeps	88.32	2.00e-178	618.00
IUUC-Oan-072808	Ornithorhynchus anatinus	87.01	0.00e+00	742.00
IUUC-Ocu-074301	Oryctolagus cuniculus	87.96	0.00e+00	782.00
IUUC-Oba-074973	Oryza barthii	38.00	8.00e-41	161.00
IUUC-Obr-076444	Oryza brachyantha	50.34	2.00e-32	133.00
IUUC-Ogl-077319	Oryza glaberrima	33.41	4.00e-43	169.00
IUUC-Ogu-078074	Oryza glumaepatula	33.41	3.00e-43	169.00
IUUC-Oin-079142	Oryza indica	33.73	8.00e-43	168.00
IUUC-Olo-080565	Oryza longistaminata	33.25	1.00e-42	167.00
IUUC-Ome-081155	Oryza meridionalis	50.92	5.00e-34	139.00
IUUC-Oni-082272	Oryza nivara	33.73	8.00e-43	168.00
IUUC-Opu-083241	Oryza punctata	34.23	1.00e-47	184.00
IUUC-Oru-085257	Oryza rufipogon	33.73	8.00e-43	168.00
IUUC-Osa-086257	Oryza sativa	33.41	4.00e-43	169.00
IUUC-Ola-086802	Oryzias latipes	68.60	8.00e-137	480.00
IUUC-Olu-087597	Ostreococcus lucimarinus	32.85	2.00e-24	107.00
IUUC-Oga-088495	Otolemur garnettii	95.32	0.00e+00	798.00
IUUC-Oar-089711	Ovis aries	95.19	0.00e+00	791.00
IUUC-Ptr-091439	Pan troglodytes	95.86	0.00e+00	838.00
IUUC-Pan-092641	Papio anubis	96.40	0.00e+00	844.00
IUUC-Psi-093518	Pelodiscus sinensis	82.96	0.00e+00	715.00
IUUC-Pma-094727	Petromyzon marinus	42.50	2.00e-52	200.00
IUUC-Ppa-095702	Physcomitrella patens	38.26	1.00e-41	164.00
IUUC-Pfo-096638	Poecilia formosa	68.29	7.00e-171	593.00
IUUC-Pab-098699	Pongo abelii	93.87	0.00e+00	835.00
IUUC-Pop-099549	Populus trichocarpa	35.83	7.00e-50	191.00
IUUC-Pca-100497	Procavia capensis	83.81	5.00e-134	471.00
IUUC-Pva-102513	Pteropus vampyrus	85.68	8.00e-146	510.00
IUUC-Pgr-103261	Puccinia graminis	54.76	2.00e-07	50.10
IUUC-Rno-104908	Rattus norvegicus	84.79	0.00e+00	838.00
IUUC-Sce-106332	Saccharomyces cerevisiae	34.09	6.00e-17	81.60
IUUC-Sha-106881	Sarcophilus harrisii	83.40	0.00e+00	700.00
IUUC-Spo-108223	Schizosaccharomyces pombe	29.03	3.00e-12	65.90
IUUC-Smo-109502	Selaginella moellendorffii	36.15	2.00e-37	150.00
IUUC-Sly-111731	Solanum lycopersicum	39.44	4.00e-41	162.00
IUUC-Stu-112263	Solanum tuberosum	35.40	2.00e-37	149.00
IUUC-Sar-113648	Sorex araneus	89.98	0.00e+00	630.00
IUUC-Sbi-114307	Sorghum bicolor	37.79	9.00e-43	167.00
IUUC-Sre-115081	Sporisorium reilianum	25.30	9.00e-12	64.30
IUUC-Ssc-115820	Sus scrofa	97.84	0.00e+00	839.00
IUUC-Tgu-116845	Taeniopygia guttata	78.95	0.00e+00	674.00
IUUC-Tni-119780	Tetraodon nigroviridis	65.49	2.00e-169	588.00
IUUC-Tae-125419	Triticum aestivum	49.65	1.00e-37	151.00
IUUC-Tur-126248	Triticum urartu	49.65	4.00e-38	152.00
IUUC-Tme-127116	Tuber melanosporum	25.91	2.00e-09	57.40
IUUC-Tbe-127379	Tupaia belangeri	82.83	0.00e+00	667.00
IUUC-Ttr-128630	Tursiops truncatus	95.21	0.00e+00	832.00
IUUC-Uma-129639	Ustilago maydis	26.19	2.00e-11	63.50
IUUC-Vpa-130413	Vicugna pacos	71.91	2.00e-160	558.00
IUUC-Vvi-131599	Vitis vinifera	39.86	1.00e-40	160.00
IUUC-Xtr-132595	Xenopus tropicalis	79.71	0.00e+00	692.00
IUUC-Xma-134155	Xiphophorus maculatus	63.08	3.00e-149	521.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence