iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132508

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01034999

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000030962.1	ENSXETT00000063235.1	ENSXETP00000060723.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	8.10e-10	38.8	364	409
E3 activity/RING/RING	4.90e-07	30.4	367	405

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplt 51
           ++ C++ + l  +Pv++p+G+ty  +++e++l+++ k cP++++ l 
   Q: 364  DLDCSLCMRLLYEPVTTPCGHTYCLKCLERCLDHNPK-CPLCKEDLC 409
           689*********************************9.*****9985 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+  + + p+++pCgH+++++Cl++          + +CPlC+
   Q: 367  CSLCMRLLYE-PVTTPCGHTYCLKCLERC------LDHNPKCPLCK 405
           ******9978.***************999......9*********7 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

LLLKRADCLA CSGRLQDACD LFQRAAMHKK VCAEDLEALV SCLADHIRTK EGLPPPDQRV 60
AKSAVLTCRQ CQGFFFEPVT LLCGHTFCKK CLECQGGSKS ECKVCRVSTE HPFRVNVLLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCTGCTGA AGAGGGCAGA CTGCTTGGCA TGCTCGGGAA GACTGCAGGA TGCCTGCGAC 60
TTGTTTCAGA GGGCTGCGAT GCACAAAAAG GTGTGCGCGG AGGATCTGGA AGCTCTGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR023114--Elongated_TPR_rpt_dom
IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51787--LON_N
PS50005--TPR
PS50293--TPR_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02190--LON_substr_bdg
PF13445--zf-RING_UBOX

SMART

SM00464--LON
SM00184--RING
SM00028--TPR

Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001774	Ailuropoda melanoleuca	49.01	3.00e-177	615.00
IUUC-Atr-002972	Amborella trichopoda	39.35	3.00e-46	179.00
IUUC-Apl-003916	Anas platyrhynchos	60.83	0.00e+00	628.00
IUUC-Ani-009473	Aspergillus nidulans	31.85	8.00e-43	168.00
IUUC-Ang-009643	Aspergillus niger	28.88	1.00e-39	157.00
IUUC-Ame-010881	Astyanax mexicanus	53.24	0.00e+00	661.00
IUUC-Bta-012872	Bos taurus	55.70	0.00e+00	657.00
IUUC-Bol-016442	Brassica oleracea	30.99	3.00e-39	155.00
IUUC-Bra-016716	Brassica rapa	32.80	2.00e-36	146.00
IUUC-Cja-018747	Callithrix jacchus	49.57	3.00e-165	575.00
IUUC-Cfa-020101	Canis familiaris	50.99	0.00e+00	647.00
IUUC-Cpo-022041	Cavia porcellus	49.79	2.00e-175	608.00
IUUC-Csa-024034	Chlorocebus sabaeus	52.57	0.00e+00	668.00
IUUC-Dno-029518	Dasypus novemcinctus	47.34	1.00e-160	560.00
IUUC-Dor-031132	Dipodomys ordii	51.09	0.00e+00	652.00
IUUC-Eca-033382	Equus caballus	52.57	0.00e+00	676.00
IUUC-Fca-035777	Felis catus	54.00	8.00e-142	496.00
IUUC-Fal-036730	Ficedula albicollis	64.67	0.00e+00	694.00
IUUC-Gmo-039110	Gadus morhua	52.53	0.00e+00	663.00
IUUC-Gga-041187	Gallus gallus	61.48	0.00e+00	842.00
IUUC-Gac-042201	Gasterosteus aculeatus	51.70	0.00e+00	674.00
IUUC-Gma-042919	Glycine max	35.35	4.00e-38	152.00
IUUC-Ggo-045111	Gorilla gorilla	52.86	0.00e+00	668.00
IUUC-Hsa-045695	Homo sapiens	52.86	0.00e+00	666.00
IUUC-Lch-050429	Latimeria chalumnae	57.16	0.00e+00	775.00
IUUC-Lma-053145	Leptosphaeria maculans	29.27	2.00e-39	157.00
IUUC-Laf-053434	Loxodonta africana	58.68	6.00e-174	603.00
IUUC-Mcc-055249	Macaca mulatta	54.83	6.00e-143	500.00
IUUC-Mla-058946	Melampsora laricipopulina	32.99	5.00e-42	165.00
IUUC-Mga-060131	Meleagris gallopavo	63.71	0.00e+00	633.00
IUUC-Mmr-060749	Microcebus murinus	52.50	0.00e+00	676.00
IUUC-Mdo-062261	Monodelphis domestica	51.12	0.00e+00	664.00
IUUC-Mmu-063219	Mus musculus	50.00	0.00e+00	628.00
IUUC-Mac-065566	Musa acuminata	28.26	1.00e-42	167.00
IUUC-Mpu-066222	Mustela putorius furo	49.15	1.00e-172	600.00
IUUC-Mlu-067769	Myotis lucifugus	50.57	0.00e+00	650.00
IUUC-Nle-069738	Nomascus leucogenys	58.97	1.00e-178	619.00
IUUC-Ont-072029	Oreochromis niloticus	51.22	0.00e+00	637.00
IUUC-Oan-073179	Ornithorhynchus anatinus	62.06	7.00e-177	613.00
IUUC-Ocu-074884	Oryctolagus cuniculus	50.79	0.00e+00	637.00
IUUC-Ola-086698	Oryzias latipes	51.82	0.00e+00	663.00
IUUC-Oga-089109	Otolemur garnettii	51.77	0.00e+00	658.00
IUUC-Oar-089903	Ovis aries	52.50	0.00e+00	664.00
IUUC-Ptr-091238	Pan troglodytes	52.49	0.00e+00	661.00
IUUC-Pan-092379	Papio anubis	49.40	0.00e+00	647.00
IUUC-Psi-093418	Pelodiscus sinensis	61.31	0.00e+00	717.00
IUUC-Pfo-097284	Poecilia formosa	52.80	0.00e+00	675.00
IUUC-Pab-098343	Pongo abelii	49.27	0.00e+00	644.00
IUUC-Pop-100044	Populus trichocarpa	36.95	1.00e-41	164.00
IUUC-Pca-100905	Procavia capensis	49.58	3.00e-153	535.00
IUUC-Ppe-101621	Prunus persica	41.89	2.00e-37	150.00
IUUC-Pva-102242	Pteropus vampyrus	47.88	3.00e-164	572.00
IUUC-Rno-105899	Rattus norvegicus	49.19	0.00e+00	634.00
IUUC-Sha-107565	Sarcophilus harrisii	48.24	4.00e-179	621.00
IUUC-Spo-108344	Schizosaccharomyces pombe	33.85	1.00e-24	107.00
IUUC-Sly-111396	Solanum lycopersicum	35.64	9.00e-42	164.00
IUUC-Ssc-115705	Sus scrofa	52.58	0.00e+00	664.00
IUUC-Tgu-116978	Taeniopygia guttata	65.62	0.00e+00	795.00
IUUC-Tsy-118988	Tarsius syrichta	59.37	4.00e-173	600.00
IUUC-Tni-119913	Tetraodon nigroviridis	46.54	2.00e-165	575.00
IUUC-Ttr-128875	Tursiops truncatus	75.50	1.00e-133	470.00
IUUC-Uma-129541	Ustilago maydis	30.47	1.00e-33	138.00
IUUC-Vpa-130779	Vicugna pacos	74.13	2.00e-125	442.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence