iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007811

Ensembl Protein ID

AAS53922

UniProt Accession

Q752M3; Q752M3_ASHGO

Genbank Protein ID

AAS53922.2

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

AE016819

Gene Name

AGOS_AFR551W

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_AFR551W	AAS53922	AAS53922

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.70e-73	244.0	138	466

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeel.......................wkskkkavsprellkalk 78
           Gl N+g tC+m Sv+Q+ +++p + +++le  +  +++    +++  ++++++ +++++l                       ++ +k++    +ll++ +
   Q: 138  GLVNMGSTCFMSSVIQTFLHLPHVLQYMLErLHYATCDV---QDSLSCISCAVDEIVANLygqvkeeaasgvagpgastqalsQSLSKQQQGFINLLTCSW 235
           9*****************************444444443...688999999999999999666666666666655555433221333334444559999** PP
   S: 79   keaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs.sreepfldlslpvpg 178
           k+++++ gy+qqDa+Ef++fll+ql+++  +                   + + +kk+   ++++ lFqg l+s+i+c ec+ ++ ++ +p +dlsl +++
   Q: 236  KINRNLAGYSQQDAHEFWQFLLNQLHTDYIR------------------IHGPPSKKSACGCILHMLFQGYLESSIVCSECHGNNkTTVDPIMDLSLGIQN 318
           *****************************33..................345678899999********************877769************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke.kkkY 278
           k+     +l++cL+sf+++e+l++ n y c++c + ++  ++l++ klP+vL+l+LkRf+   + + + kin++++fpl+L+++ +c   +++  + + ++
   Q: 319  KS-----TLHECLDSFHRRESLTDFN-YCCKNCMSTSNPIRQLSMAKLPPVLMLQLKRFEHLIN-GTSVKINDYISFPLHLNMKDYCKPMDDQHPVpNMTF 412
           **.....9**************9765.********************************88665.8889******************996655544689** PP
   S: 279  eLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfY 335
           +L+a+++H+G++++GHY+++++ + + W +f+Ds Vt ++ee++l+   ++aY+l+Y
   Q: 413  KLSAIISHQGTVDKGHYTTICRINGDVWAKFNDSMVTLISEEDMLK---EQAYLLYY 466
           ***********************9999*******************...*******9 PP

Organism

Ashbya gossypii

Protein Sequence
(Fasta)

MMVCPHMEQV IQTAKVGDAV VKECITVRYL IRNCDAKSRY LRAMRCSECF QINCGSSFMC 60
LQCGFVGCWN ESHFLHHSKK VGHIFGVNAT NGLLFCFRCR DYISDNEFVH MDIMPKHWNE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATGGTGT GTCCGCATAT GGAGCAGGTG ATCCAGACGG CGAAGGTGGG CGATGCAGTG 60
GTGAAAGAGT GCATCACAGT ACGATATCTG ATCCGCAACT GCGATGCCAA GAGCAGGTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0071819--C:DUBm complex
GO:0000124--C:SAGA complex
GO:0046695--C:SLIK (SAGA-like) complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016578--P:histone deubiquitination
GO:0051568--P:histone H3-K4 methylation
GO:0034729--P:histone H3-K79 methylation
GO:0008380--P:RNA splicing
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ago:AGOS_AFR551W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000393	Aegilops tauschii	29.31	8.00e-35	139.00
IUUC-Aml-001343	Ailuropoda melanoleuca	30.58	2.00e-53	201.00
IUUC-Atr-002653	Amborella trichopoda	29.28	2.00e-50	191.00
IUUC-Apl-003433	Anas platyrhynchos	30.18	5.00e-52	196.00
IUUC-Aca-005347	Anolis carolinensis	28.82	2.00e-50	191.00
IUUC-Aly-006565	Arabidopsis lyrata	26.54	2.00e-33	134.00
IUUC-Ath-007536	Arabidopsis thaliana	26.54	7.00e-34	136.00
IUUC-Acl-008124	Aspergillus clavatus	33.41	1.00e-59	221.00
IUUC-Afl-008464	Aspergillus flavus	35.04	1.00e-48	184.00
IUUC-Afu-008912	Aspergillus fumigatus	32.32	3.00e-57	213.00
IUUC-Ani-009168	Aspergillus nidulans	34.01	1.00e-57	215.00
IUUC-Ang-009694	Aspergillus niger	32.20	5.00e-56	209.00
IUUC-Aor-010035	Aspergillus oryzae	38.91	3.00e-41	159.00
IUUC-Ate-010382	Aspergillus terreus	33.66	7.00e-51	192.00
IUUC-Ame-011253	Astyanax mexicanus	29.11	7.00e-43	166.00
IUUC-Bgr-012150	Blumeria graminis	29.68	5.00e-47	179.00
IUUC-Bta-013303	Bos taurus	30.58	2.00e-54	204.00
IUUC-Bci-013604	Botrytis cinerea	32.33	5.00e-55	206.00
IUUC-Bdi-014171	Brachypodium distachyon	27.33	1.00e-39	155.00
IUUC-Bol-016509	Brassica oleracea	27.67	8.00e-38	149.00
IUUC-Bra-016962	Brassica rapa	27.25	9.00e-39	152.00
IUUC-Cja-019283	Callithrix jacchus	30.73	5.00e-48	182.00
IUUC-Cfa-021239	Canis familiaris	31.57	7.00e-55	205.00
IUUC-Cpo-022354	Cavia porcellus	30.60	2.00e-55	207.00
IUUC-Cre-022988	Chlamydomonas reinhardtii	30.43	1.00e-26	111.00
IUUC-Csa-023145	Chlorocebus sabaeus	30.40	4.00e-54	203.00
IUUC-Cho-024863	Choloepus hoffmanni	32.33	1.00e-21	95.90
IUUC-Csv-026214	Ciona savignyi	28.38	3.00e-49	187.00
IUUC-Cgl-026457	Colletotrichum gloeosporioides	31.52	2.00e-52	197.00
IUUC-Cne-027085	Cryptococcus neoformans	26.45	8.00e-38	149.00
IUUC-Dre-027433	Danio rerio	31.20	3.00e-54	203.00
IUUC-Dno-030095	Dasypus novemcinctus	31.14	4.00e-54	202.00
IUUC-Dse-031415	Dothistroma septosporum	29.17	3.00e-63	233.00
IUUC-Dme-032074	Drosophila melanogaster	27.61	4.00e-50	189.00
IUUC-Ete-032611	Echinops telfairi	25.34	1.00e-22	98.60
IUUC-Eca-033736	Equus caballus	31.57	8.00e-55	205.00
IUUC-Eeu-035268	Erinaceus europaeus	26.27	9.00e-22	95.90
IUUC-Fca-035861	Felis catus	31.57	6.00e-55	206.00
IUUC-Fal-037645	Ficedula albicollis	30.18	4.00e-52	196.00
IUUC-Fox-038046	Fusarium oxysporum	31.39	2.00e-53	201.00
IUUC-Fso-038321	Fusarium solani	30.57	4.00e-49	186.00
IUUC-Gmo-039598	Gadus morhua	26.92	2.00e-34	138.00
IUUC-Ggr-040044	Gaeumannomyces graminis	31.24	2.00e-52	197.00
IUUC-Gga-040624	Gallus gallus	29.67	3.00e-52	197.00
IUUC-Gac-042197	Gasterosteus aculeatus	29.28	5.00e-48	183.00
IUUC-Gma-043933	Glycine max	28.95	8.00e-49	186.00
IUUC-Ggo-044409	Gorilla gorilla	30.58	1.00e-54	204.00
IUUC-Hsa-046521	Homo sapiens	30.58	2.00e-54	204.00
IUUC-Hvu-047739	Hordeum vulgare	30.13	4.00e-39	152.00
IUUC-Itr-048375	Ictidomys tridecemlineatus	30.60	1.00e-55	208.00
IUUC-Kpa-049135	Komagataella pastoris	36.42	3.00e-86	310.00
IUUC-Lch-050537	Latimeria chalumnae	30.77	2.00e-53	201.00
IUUC-Lpe-050969	Leersia perrieri	30.73	1.00e-39	154.00
IUUC-Loc-052765	Lepisosteus oculatus	27.79	3.00e-42	163.00
IUUC-Lma-053105	Leptosphaeria maculans	32.46	7.00e-58	216.00
IUUC-Laf-053571	Loxodonta africana	31.57	5.00e-55	206.00
IUUC-Mcc-055166	Macaca mulatta	30.40	4.00e-54	203.00
IUUC-Mor-057103	Magnaporthe oryzae	29.76	3.00e-50	190.00
IUUC-Mpo-057621	Magnaporthe poae	32.16	2.00e-54	204.00
IUUC-Mtr-057894	Medicago truncatula	29.76	2.00e-46	178.00
IUUC-Mla-059185	Melampsora laricipopulina	29.20	8.00e-46	175.00
IUUC-Mga-059709	Meleagris gallopavo	30.18	5.00e-52	196.00
IUUC-Mvi-060530	Microbotryum violaceum	30.22	7.00e-43	166.00
IUUC-Mmr-060988	Microcebus murinus	30.38	5.00e-55	206.00
IUUC-Mdo-063065	Monodelphis domestica	30.57	7.00e-54	202.00
IUUC-Mmu-063829	Mus musculus	30.78	1.00e-54	204.00
IUUC-Mac-065419	Musa acuminata	30.61	5.00e-39	153.00
IUUC-Mpu-066687	Mustela putorius furo	30.58	2.00e-54	204.00
IUUC-Mlu-067330	Myotis lucifugus	30.00	3.00e-52	197.00
IUUC-Nfi-068423	Neosartorya fischeri	32.32	1.00e-56	212.00
IUUC-Ncr-068809	Neurospora crassa	28.81	4.00e-48	183.00
IUUC-Nle-069859	Nomascus leucogenys	29.55	2.00e-49	188.00
IUUC-Ont-071961	Oreochromis niloticus	29.30	1.00e-49	188.00
IUUC-Oan-073565	Ornithorhynchus anatinus	28.60	2.00e-49	187.00
IUUC-Ocu-074951	Oryctolagus cuniculus	28.81	4.00e-52	196.00
IUUC-Oba-075688	Oryza barthii	30.05	7.00e-39	152.00
IUUC-Obr-076652	Oryza brachyantha	29.55	4.00e-39	152.00
IUUC-Ogl-077910	Oryza glaberrima	30.05	6.00e-39	153.00
IUUC-Ogu-078479	Oryza glumaepatula	29.80	2.00e-38	151.00
IUUC-Oin-079697	Oryza indica	29.80	2.00e-38	151.00
IUUC-Olo-080811	Oryza longistaminata	31.34	1.00e-29	120.00
IUUC-Ome-081706	Oryza meridionalis	30.05	1.00e-38	152.00
IUUC-Oni-083070	Oryza nivara	29.80	9.00e-39	152.00
IUUC-Opu-083605	Oryza punctata	28.72	3.00e-33	133.00
IUUC-Oru-084522	Oryza rufipogon	30.05	6.00e-39	153.00
IUUC-Osa-085351	Oryza sativa	29.80	1.00e-38	152.00
IUUC-Ola-086743	Oryzias latipes	33.51	1.00e-45	174.00
IUUC-Olu-087695	Ostreococcus lucimarinus	29.31	4.00e-36	142.00
IUUC-Oga-089131	Otolemur garnettii	29.63	2.00e-53	201.00
IUUC-Oar-089319	Ovis aries	31.36	5.00e-54	202.00
IUUC-Ptr-090783	Pan troglodytes	31.36	2.00e-54	204.00
IUUC-Pan-092927	Papio anubis	30.40	3.00e-54	203.00
IUUC-Psi-093670	Pelodiscus sinensis	30.18	4.00e-52	196.00
IUUC-Pma-094323	Petromyzon marinus	27.64	6.00e-42	162.00
IUUC-Pno-095141	Phaeosphaeria nodorum	30.27	2.00e-53	201.00
IUUC-Ppa-095413	Physcomitrella patens	30.35	5.00e-42	163.00
IUUC-Pfo-096473	Poecilia formosa	30.41	7.00e-53	199.00
IUUC-Pab-097612	Pongo abelii	30.58	2.00e-54	204.00
IUUC-Pop-099893	Populus trichocarpa	29.82	7.00e-47	179.00
IUUC-Pca-100329	Procavia capensis	29.18	3.00e-52	197.00
IUUC-Ppe-101583	Prunus persica	27.78	3.00e-40	157.00
IUUC-Pva-102721	Pteropus vampyrus	28.81	2.00e-46	178.00
IUUC-Pgr-103657	Puccinia graminis	26.24	2.00e-36	144.00
IUUC-Pte-104340	Pyrenophora teres	31.18	6.00e-51	192.00
IUUC-Pyt-104782	Pyrenophora triticirepentis	33.03	2.00e-57	214.00
IUUC-Rno-105247	Rattus norvegicus	30.78	1.00e-54	205.00
IUUC-Sce-106247	Saccharomyces cerevisiae	50.73	7.00e-146	508.00
IUUC-Sja-107656	Schizosaccharomyces japonicus	30.41	2.00e-54	204.00
IUUC-Spo-108226	Schizosaccharomyces pombe	32.80	3.00e-60	223.00
IUUC-Ssl-108531	Sclerotinia sclerotiorum	31.13	2.00e-52	197.00
IUUC-Smo-109310	Selaginella moellendorffii	29.70	6.00e-50	189.00
IUUC-Sit-109716	Setaria italica	27.59	2.00e-37	148.00
IUUC-Sly-111077	Solanum lycopersicum	27.26	1.00e-40	158.00
IUUC-Stu-112203	Solanum tuberosum	30.70	1.00e-39	154.00
IUUC-Sar-113174	Sorex araneus	30.22	4.00e-43	166.00
IUUC-Sbi-114205	Sorghum bicolor	27.73	7.00e-38	149.00
IUUC-Ssc-115315	Sus scrofa	28.84	8.00e-51	192.00
IUUC-Tgu-116938	Taeniopygia guttata	31.14	8.00e-54	202.00
IUUC-Tru-118304	Takifugu rubripes	28.94	1.00e-51	194.00
IUUC-Tsy-119413	Tarsius syrichta	28.72	5.00e-49	186.00
IUUC-Tni-120661	Tetraodon nigroviridis	30.02	7.00e-53	199.00
IUUC-Tca-121154	Theobroma cacao	28.85	5.00e-46	176.00
IUUC-Tre-122139	Trichoderma reesei	30.41	1.00e-48	184.00
IUUC-Tvi-122599	Trichoderma virens	29.35	1.00e-48	185.00
IUUC-Tae-125608	Triticum aestivum	27.93	4.00e-44	170.00
IUUC-Tme-127115	Tuber melanosporum	32.82	6.00e-66	242.00
IUUC-Tbe-127423	Tupaia belangeri	31.85	9.00e-21	92.40
IUUC-Ttr-129006	Tursiops truncatus	29.03	6.00e-51	192.00
IUUC-Uma-129455	Ustilago maydis	27.78	3.00e-25	108.00
IUUC-Vda-129829	Verticillium dahliae	37.21	1.00e-37	147.00
IUUC-Vvi-131477	Vitis vinifera	29.64	6.00e-41	159.00
IUUC-Xtr-132444	Xenopus tropicalis	29.67	5.00e-52	196.00
IUUC-Xma-133514	Xiphophorus maculatus	30.52	2.00e-51	194.00
IUUC-Yli-134357	Yarrowia lipolytica	31.57	3.00e-47	180.00
IUUC-Zma-134945	Zea mays	29.87	3.00e-35	140.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence