iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ate-010253

Ensembl Protein ID

CADATEAP00009202

UniProt Accession

Q0CQP3; Q0CQP3_ASPTN

Genbank Protein ID

EAU35793.1

Protein Name

HECT

Genbank Nucleotide ID

CH476598

Gene Name

ATEG_03991

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADATEAG00009202	CADATEAT00009202	CADATEAP00009202

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.40e-118	395.2	3700	4031

Active Site

Position(s)	Description	Evidence
4000	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkk.rlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpls 93
           +lk+ +l+v+f gEeg+d+gGvtre+++ l++ ++np++ lf   + d++t++pn+ sg+ n ehl +F+f+Gr++gkal++gr+ld+++s
   Q: 3700 ELKYgKLNVRFHGEEGVDAGGVTREWFQVLARGMFNPNYALFIPVAADRTTFHPNRLSGV-NSEHLMFFKFIGRIIGKALYEGRVLDCHFS 3789
           66755899***************************************************9.56**************************** PP
   S: 94   ksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlke 184
           +++yk++lg+++s++d+e++d ++yksl +++en   di+++ ++ tf v+++ +ge ++ +L+++G+nipVt+eNkeeYv++vv+yrl +
   Q: 3790 RAVYKCILGRSVSIKDMETLDLDYYKSLLWMLEN---DITDI-ITETFAVETDDFGEKQVIDLVENGRNIPVTQENKEEYVQRVVDYRLLR 3876
           ********************************99...99999.999********************************************* PP
   S: 185  gikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlP 275
           ++keq+++f +Gf+e+ip++l+s+F+e+elelli+G +eidv+d+k +t+y++ y+++sp+iqwFw+++++f++eer+++LqFvTg+s++P
   Q: 3877 SVKEQLDNFLKGFHEIIPPDLISIFNEQELELLISGLPEIDVDDWKVNTEYHN-YSASSPQIQWFWRAVRSFDKEERAKLLQFVTGTSKVP 3966
           ***************************************************66.************************************* PP
   S: 276  lgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFe 334
           l+Gf+el+     ++f i++ ++++drlPss+TCfn+L+LPeY+s+e+l+++L +A++ + + F+
   Q: 3967 LNGFKELEgmngVSRFNIHRdYGNKDRLPSSHTCFNQLDLPEYESYETLRQRLYTAMTAGsEYFG 4031
           ********99996667777768999********************************99877776 PP

Organism

Aspergillus terreus

Protein Sequence
(Fasta)

MGRIKKVASQ KHEATISPYL SEFVSRALTV PIPELPSHLS TFLRIWPFPR GDLYHWINVL 60
NRFDEILAVV IEKYDLNNGP QTKPFGRHAL VDFYAGDGNK LNPEEANVKL SALGYGPEGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGAGAA TCAAGAAGGT GGCTAGCCAA AAACATGAGG CTACGATCGT AAGTTTTCCT 60
TTTTCTTCCC CTCACCAAGT GCTGTACAGC ATCAGCCTGA AGCTCAACTA AGATTTTTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	31.99	4.00e-117	416.00
IUUC-Aml-001684	Ailuropoda melanoleuca	46.55	4.00e-133	469.00
IUUC-Atr-003044	Amborella trichopoda	41.46	7.00e-139	488.00
IUUC-Apl-003729	Anas platyrhynchos	51.83	5.00e-100	355.00
IUUC-Aca-005263	Anolis carolinensis	46.62	9.00e-135	474.00
IUUC-Aly-006157	Arabidopsis lyrata	41.33	2.00e-139	489.00
IUUC-Ath-007472	Arabidopsis thaliana	43.78	1.00e-136	481.00
IUUC-Ago-008005	Ashbya gossypii	57.19	0.00e+00	745.00
IUUC-Acl-008254	Aspergillus clavatus	74.59	0.00e+00	3472.00
IUUC-Afl-008712	Aspergillus flavus	90.53	0.00e+00	1919.00
IUUC-Afu-009022	Aspergillus fumigatus	78.51	0.00e+00	5793.00
IUUC-Ani-009412	Aspergillus nidulans	70.57	0.00e+00	3651.00
IUUC-Ang-009771	Aspergillus niger	79.10	0.00e+00	5969.00
IUUC-Aor-010186	Aspergillus oryzae	87.21	0.00e+00	2227.00
IUUC-Ame-011067	Astyanax mexicanus	46.39	2.00e-132	467.00
IUUC-Bgr-012043	Blumeria graminis	52.97	0.00e+00	1325.00
IUUC-Bta-012813	Bos taurus	46.55	3.00e-133	469.00
IUUC-Bci-013995	Botrytis cinerea	58.78	0.00e+00	1240.00
IUUC-Bdi-014884	Brachypodium distachyon	35.03	1.00e-138	487.00
IUUC-Bol-016533	Brassica oleracea	55.27	1.00e-91	327.00
IUUC-Bra-016726	Brassica rapa	39.51	9.00e-139	488.00
IUUC-Cel-018179	Caenorhabditis elegans	51.76	6.00e-130	458.00
IUUC-Cja-018741	Callithrix jacchus	46.36	2.00e-132	466.00
IUUC-Cfa-020083	Canis familiaris	46.55	5.00e-133	469.00
IUUC-Cpo-021766	Cavia porcellus	42.79	3.00e-97	348.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	52.25	3.00e-132	462.00
IUUC-Csa-023853	Chlorocebus sabaeus	46.55	4.00e-133	469.00
IUUC-Cho-024718	Choloepus hoffmanni	56.27	9.00e-122	431.00
IUUC-Cin-025627	Ciona intestinalis	52.07	4.00e-132	466.00
IUUC-Csv-025872	Ciona savignyi	51.84	7.00e-129	451.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	59.84	0.00e+00	1250.00
IUUC-Cne-027095	Cryptococcus neoformans	38.54	0.00e+00	670.00
IUUC-Cme-027267	Cyanidioschyzon merolae	51.79	2.00e-120	426.00
IUUC-Dre-028525	Danio rerio	45.08	2.00e-120	427.00
IUUC-Dno-029680	Dasypus novemcinctus	46.55	3.00e-133	469.00
IUUC-Dor-030902	Dipodomys ordii	48.23	8.00e-113	402.00
IUUC-Dse-031197	Dothistroma septosporum	35.99	0.00e+00	1308.00
IUUC-Dme-032122	Drosophila melanogaster	50.00	1.00e-129	458.00
IUUC-Ete-032966	Echinops telfairi	42.79	3.00e-97	348.00
IUUC-Eca-033915	Equus caballus	45.68	2.00e-130	461.00
IUUC-Eeu-034963	Erinaceus europaeus	53.07	5.00e-131	462.00
IUUC-Fca-035824	Felis catus	46.55	4.00e-133	469.00
IUUC-Fox-037756	Fusarium oxysporum	58.57	0.00e+00	1270.00
IUUC-Fso-038464	Fusarium solani	58.50	0.00e+00	1259.00
IUUC-Gmo-039073	Gadus morhua	46.36	1.00e-133	471.00
IUUC-Ggr-039946	Gaeumannomyces graminis	57.23	0.00e+00	1214.00
IUUC-Gga-040309	Gallus gallus	57.98	2.00e-105	373.00
IUUC-Gac-042430	Gasterosteus aculeatus	46.36	2.00e-133	470.00
IUUC-Gma-043129	Glycine max	32.45	2.00e-154	540.00
IUUC-Ggo-044465	Gorilla gorilla	42.56	2.00e-96	345.00
IUUC-Hsa-046879	Homo sapiens	46.55	5.00e-133	469.00
IUUC-Hvu-047697	Hordeum vulgare	33.84	2.00e-137	483.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	46.55	5.00e-134	471.00
IUUC-Kpa-049228	Komagataella pastoris	60.40	0.00e+00	783.00
IUUC-Lch-050252	Latimeria chalumnae	46.85	8.00e-133	468.00
IUUC-Lpe-051550	Leersia perrieri	34.24	1.00e-138	487.00
IUUC-Loc-052472	Lepisosteus oculatus	46.74	1.00e-134	474.00
IUUC-Lma-053159	Leptosphaeria maculans	41.54	0.00e+00	1652.00
IUUC-Laf-054154	Loxodonta africana	46.55	3.00e-133	469.00
IUUC-Mcc-055085	Macaca mulatta	46.55	4.00e-133	469.00
IUUC-Mor-057201	Magnaporthe oryzae	56.67	0.00e+00	1204.00
IUUC-Mpo-057597	Magnaporthe poae	70.87	0.00e+00	958.00
IUUC-Mtr-058128	Medicago truncatula	41.14	2.00e-140	493.00
IUUC-Mla-058888	Melampsora laricipopulina	58.23	8.00e-144	501.00
IUUC-Mga-059935	Meleagris gallopavo	42.79	6.00e-97	347.00
IUUC-Mvi-060320	Microbotryum violaceum	44.49	0.00e+00	754.00
IUUC-Mmr-060820	Microcebus murinus	46.55	4.00e-133	469.00
IUUC-Mdo-062930	Monodelphis domestica	46.43	2.00e-134	473.00
IUUC-Mmu-063601	Mus musculus	46.55	4.00e-133	469.00
IUUC-Mac-065229	Musa acuminata	32.76	9.00e-154	537.00
IUUC-Mpu-066653	Mustela putorius furo	53.43	6.00e-133	469.00
IUUC-Mlu-067418	Myotis lucifugus	45.54	1.00e-133	471.00
IUUC-Nfi-068278	Neosartorya fischeri	74.89	0.00e+00	3455.00
IUUC-Ncr-068813	Neurospora crassa	33.66	0.00e+00	1131.00
IUUC-Nle-069418	Nomascus leucogenys	46.55	4.00e-133	469.00
IUUC-Ont-071300	Oreochromis niloticus	46.36	1.00e-133	471.00
IUUC-Oan-073046	Ornithorhynchus anatinus	46.86	1.00e-133	471.00
IUUC-Ocu-074178	Oryctolagus cuniculus	46.55	2.00e-133	470.00
IUUC-Oba-075757	Oryza barthii	34.00	2.00e-142	500.00
IUUC-Obr-076553	Oryza brachyantha	41.51	9.00e-140	491.00
IUUC-Ogl-077520	Oryza glaberrima	34.00	3.00e-142	499.00
IUUC-Ogu-078278	Oryza glumaepatula	40.17	3.00e-140	493.00
IUUC-Oin-079767	Oryza indica	34.00	1.00e-142	501.00
IUUC-Olo-080380	Oryza longistaminata	39.94	2.00e-138	486.00
IUUC-Ome-081925	Oryza meridionalis	33.96	1.00e-140	494.00
IUUC-Oni-082619	Oryza nivara	33.77	1.00e-142	501.00
IUUC-Opu-083684	Oryza punctata	36.33	1.00e-139	491.00
IUUC-Oru-084501	Oryza rufipogon	34.00	1.00e-142	500.00
IUUC-Osa-086251	Oryza sativa	40.17	1.00e-139	488.00
IUUC-Ola-086777	Oryzias latipes	42.79	3.00e-98	351.00
IUUC-Olu-087813	Ostreococcus lucimarinus	48.16	4.00e-115	406.00
IUUC-Oga-088903	Otolemur garnettii	46.55	5.00e-133	469.00
IUUC-Oar-090210	Ovis aries	46.55	4.00e-133	469.00
IUUC-Ptr-090529	Pan troglodytes	42.79	6.00e-97	347.00
IUUC-Pan-092368	Papio anubis	45.49	3.00e-120	427.00
IUUC-Pno-094871	Phaeosphaeria nodorum	41.40	0.00e+00	1628.00
IUUC-Ppa-095657	Physcomitrella patens	45.62	3.00e-131	463.00
IUUC-Pfo-096232	Poecilia formosa	46.36	8.00e-134	471.00
IUUC-Pab-098583	Pongo abelii	46.55	5.00e-133	469.00
IUUC-Pop-099468	Populus trichocarpa	32.44	4.00e-154	539.00
IUUC-Ppe-101641	Prunus persica	33.56	7.00e-153	535.00
IUUC-Pva-102116	Pteropus vampyrus	43.87	3.00e-119	423.00
IUUC-Pgr-103465	Puccinia graminis	49.15	0.00e+00	635.00
IUUC-Ptt-103813	Puccinia triticina	41.72	0.00e+00	763.00
IUUC-Pte-104018	Pyrenophora teres	61.66	0.00e+00	1314.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	62.08	0.00e+00	1318.00
IUUC-Rno-105153	Rattus norvegicus	42.79	2.00e-97	348.00
IUUC-Sce-106449	Saccharomyces cerevisiae	56.42	0.00e+00	731.00
IUUC-Sha-106961	Sarcophilus harrisii	47.42	2.00e-134	474.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	46.11	0.00e+00	925.00
IUUC-Spo-108024	Schizosaccharomyces pombe	44.31	0.00e+00	851.00
IUUC-Smo-109640	Selaginella moellendorffii	47.63	7.00e-135	474.00
IUUC-Sit-110149	Setaria italica	40.14	7.00e-137	481.00
IUUC-Sly-111706	Solanum lycopersicum	43.70	3.00e-139	489.00
IUUC-Stu-112582	Solanum tuberosum	34.46	1.00e-55	209.00
IUUC-Sar-113291	Sorex araneus	53.61	8.00e-129	455.00
IUUC-Sbi-114042	Sorghum bicolor	33.85	3.00e-148	519.00
IUUC-Sre-114958	Sporisorium reilianum	59.14	2.00e-176	610.00
IUUC-Ssc-115754	Sus scrofa	46.55	6.00e-133	468.00
IUUC-Tru-118570	Takifugu rubripes	46.36	9.00e-134	471.00
IUUC-Tni-120836	Tetraodon nigroviridis	45.02	5.00e-128	452.00
IUUC-Tca-121479	Theobroma cacao	32.96	1.00e-151	530.00
IUUC-Tre-121909	Trichoderma reesei	58.30	0.00e+00	1230.00
IUUC-Tvi-122370	Trichoderma virens	56.43	0.00e+00	1225.00
IUUC-Tae-125214	Triticum aestivum	33.43	3.00e-137	482.00
IUUC-Tme-127172	Tuber melanosporum	74.33	0.00e+00	998.00
IUUC-Ttr-129253	Tursiops truncatus	46.55	5.00e-133	469.00
IUUC-Uma-129355	Ustilago maydis	58.13	1.00e-180	624.00
IUUC-Vda-129886	Verticillium dahliae	57.56	0.00e+00	1213.00
IUUC-Vpa-130708	Vicugna pacos	46.55	8.00e-133	468.00
IUUC-Vvi-131078	Vitis vinifera	45.19	1.00e-136	480.00
IUUC-Xtr-132123	Xenopus tropicalis	45.54	3.00e-127	449.00
IUUC-Xma-133869	Xiphophorus maculatus	46.36	7.00e-134	472.00
IUUC-Yli-134657	Yarrowia lipolytica	48.38	0.00e+00	973.00
IUUC-Zma-135570	Zea mays	34.69	5.00e-143	502.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence