iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-111201

Ensembl Protein ID

Solyc09g005160.1.1

UniProt Accession

K4CQ06; K4CQ06_SOLLC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc09g005160.1	Solyc09g005160.1.1	Solyc09g005160.1.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.80e-93	312.9	490	821
ULD/UDP/UBQ/UBQ_Other	4.20e-10	40.1	36	117

Active Site

Position(s)	Description	Evidence
795	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpl 92
           +++l+ +l+++f++Ee+++  Gv re+++l++++++np++ lf+  +nd + ++pnp+s++ +p hl++F+f Gr++++al ++  + +++
   Q: 490  PKSLQGQLFIQFENEEATGP-GVLREWFSLVCEAIFNPQNALFVSCPNDGRRFFPNPASKV-DPLHLEYFTFSGRMIALALLHRVQISITF 578
           578999*************9.***************************************9.68*************************** PP
   S: 93   sksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlk 183
            ++f+ +l g+++s+ed+ + dp ly   k+i+e++ + ++e  l ltf  ++e+lg++k++eL+p+G+n+ V+ eN+++Yv+l+v++r+ 
   Q: 579  DRVFFLQLAGEDISFEDIRDADPYLYSGCKKILEMDTNMVDEDVLGLTFVCEDEELGSRKVVELCPDGKNTLVNSENRDNYVNLLVKHRFV 669
           ***********************************99999999************************************************ PP
   S: 184  egikeqveafreGfneviplell.....slFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           ++i++qv++f +Gf ++i  + l     +++++e+l+ +++G+ + ++v+d+k++t+y+ gy+ d+p+i wFwe++ ++s+e+r  +L F+
   Q: 670  TSIAQQVAHFAQGFADIITDQQLrksfyQILDHEDLNRMLHGSkTVVSVKDWKEHTNYN-GYKIDDPQISWFWEIVGSMSAEQRNVLLFFW 759
           *****************76554422222899************999************5.5****************************** PP
   S: 269  TgssrlPlgGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet 330
           T+ ++lP++Gf  l  +l ++r + s+d lPss TCf+yL+ P+Y+s+++++++L + +++ 
   Q: 760  TSIKSLPVEGFGGLDSKLHIYRTSVSHDCLPSSRTCFYYLCFPPYPSMDVMQNRLNIITQNY 821
           *******************************************************8766654 PP

ULD/UDP/UBQ/UBQ_Other

   S: 3    vtvksldgs.eltlkvnpsdtVaeLKeki.........ekklgippeqqrLiykGkiLeddktLadyglkdgstihllekks 74
           ++v+   g  +l l+ ++sd+Va + +ki         ++  g+p+ +qrLiy+Gk L+  + L+++g+++++t+ l+ +++
   Q: 36   FFVRMFSGGkTLVLQADSSDSVASVHRKIqsitgirsiQSTSGVPRMEQRLIYRGKQLQLQQRLSECGVQNDDTLQLVGRMR 117
           55555555558899999********************9999*************************************9986 PP

Organism

Solanum lycopersicum

Protein Sequence
(Fasta)

MAYRNTRRKL DDYAAADAWM RYDETLPISL SYPIQFFVRM FSGGKTLVLQ ADSSDSVASV 60
HRKIQSITGI RSIQSTSGVP RMEQRLIYRG KQLQLQQRLS ECGVQNDDTL QLVGRMRSTR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTACC GTAATACCAG ACGCAAGTTA GATGATTATG CCGCCGCAGA TGCCTGGATG 60
AGATACGACG AAACTCTCCC TATTTCTCTG TCATACCCCA TTCAGTTCTT CGTCCGTATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50237--HECT
PS50053--UBIQUITIN_2

Pfam

PF00632--HECT
PF00240--ubiquitin

SMART

SM00119--HECTc
SM00213--UBQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

sly:101253823

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ppa-095337	Physcomitrella patens	39.02	9.00e-165	573.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence