iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118068

UUCD1 version

UUC-TaR-00511

Ensembl Protein ID

ENSTRUP00000024888.1

UniProt Accession

H2TJN4; H2TJN4_TAKRU

Protein Name

Uncharacterized protein

Gene Name

ube3c

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000009905.1	ENSTRUT00000024990.1	ENSTRUP00000024888.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.60e-105	353.3	744	1081

Active Site

Position(s)	Description	Evidence
1049	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f+ ++++    +p+ ++ +     +++++flGrllgkal++
   Q: 744  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKATNDSLLYPNPAAEMLVG-DSFTRHYYFLGRLLGKALYE 829
           689**********99**9*****************************9999888888888888875.599***************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++++f+++llg+  ++++++l+++dpe+y++l ++k++ e d+eelgl++t+   ++ lge++++eLkpgG++ipVt +N
   Q: 830  NMLVELPFASFFLSKLLGTsaDVDIHHLASLDPEMYRNLLFLKSY-EGDVEELGLNFTVV--NNDLGEAQVVELKPGGKDIPVTTAN 913
           ******************9666889******************99.78999987777765..888********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl+++i+ ++ afr+G+ +v++le+l++F+++el++li+G    i ++dlkk+t+y ggyt+++p+iq+Fwev+e+
   Q: 914  RIAYIHLVADYRLNKQIRPHCLAFRQGLANVVNLEWLRMFDQQELQVLISGAhVPICLDDLKKFTNYSGGYTDTHPVIQTFWEVVEG 1000
           ****************************************************999******************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           fs+ee++++L+FvT++sr Pl Gf+el p  f+i++ ++d +rlP+++TC+n+LkLPe+  ++ +++kLlyAie+++gFels
   Q: 1001 FSQEEKRKLLKFVTSCSRPPLLGFKELYPV-FCIHNGGNDlERLPTASTCMNLLKLPEFCDQNLMRNKLLYAIESSSGFELS 1081
           ****************************66.*****99999**************************************985 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MFSFEGDFRT RPSVSLGGAS KKEEKASLLH RTQEERRKRE DERKRLKNAI IIQSFIRGYQ 60
DLKRQYATQR ASFDECVSQS LVGGAQHTLD GPRLSLLSRQ LIFFYKQSVD VHRLIWLCQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTAGTT TTGAGGGAGA TTTCCGAACA AGACCCAGTG TGTCACTTGG GGGAGCAAGC 60
AAAAAAGTAA GACATCAGTT TAACAAATCA TTCCACATTT TATAGCATTT ATTTTATATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	75.40	0.00e+00	1568.00
IUUC-Apl-003731	Anas platyrhynchos	78.56	0.00e+00	1669.00
IUUC-Aca-005248	Anolis carolinensis	78.51	0.00e+00	1687.00
IUUC-Ath-006576	Arabidopsis thaliana	33.51	6.00e-107	382.00
IUUC-Ago-007748	Ashbya gossypii	41.67	2.00e-79	290.00
IUUC-Acl-008158	Aspergillus clavatus	39.32	2.00e-77	284.00
IUUC-Afl-008398	Aspergillus flavus	39.66	2.00e-79	291.00
IUUC-Afu-008937	Aspergillus fumigatus	39.57	2.00e-79	291.00
IUUC-Ani-009252	Aspergillus nidulans	39.23	2.00e-79	291.00
IUUC-Ang-009773	Aspergillus niger	39.10	3.00e-78	287.00
IUUC-Aor-009940	Aspergillus oryzae	39.66	2.00e-79	290.00
IUUC-Ate-010395	Aspergillus terreus	38.03	7.00e-79	289.00
IUUC-Ame-010769	Astyanax mexicanus	66.60	0.00e+00	1100.00
IUUC-Bgr-012269	Blumeria graminis	37.61	2.00e-73	269.00
IUUC-Bta-012841	Bos taurus	76.31	0.00e+00	1622.00
IUUC-Bci-013743	Botrytis cinerea	37.08	2.00e-79	290.00
IUUC-Bol-015390	Brassica oleracea	35.65	1.00e-101	364.00
IUUC-Bra-016853	Brassica rapa	36.42	1.00e-108	387.00
IUUC-Cel-018638	Caenorhabditis elegans	39.52	3.00e-89	323.00
IUUC-Cja-019743	Callithrix jacchus	74.91	0.00e+00	1578.00
IUUC-Cfa-021031	Canis familiaris	76.75	0.00e+00	1630.00
IUUC-Cpo-022401	Cavia porcellus	77.01	0.00e+00	1630.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	44.50	3.00e-85	308.00
IUUC-Csa-024107	Chlorocebus sabaeus	76.73	0.00e+00	1637.00
IUUC-Cho-024750	Choloepus hoffmanni	73.75	0.00e+00	719.00
IUUC-Cin-025432	Ciona intestinalis	46.10	1.00e-97	350.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	33.51	1.00e-82	301.00
IUUC-Cne-026841	Cryptococcus neoformans	36.04	9.00e-94	338.00
IUUC-Cme-027265	Cyanidioschyzon merolae	47.58	2.00e-105	377.00
IUUC-Dre-028196	Danio rerio	83.16	0.00e+00	1721.00
IUUC-Dno-029024	Dasypus novemcinctus	77.05	0.00e+00	1639.00
IUUC-Dor-030483	Dipodomys ordii	80.94	9.00e-172	597.00
IUUC-Dse-031416	Dothistroma septosporum	33.96	1.00e-76	281.00
IUUC-Dme-031946	Drosophila melanogaster	48.13	5.00e-179	621.00
IUUC-Ete-032240	Echinops telfairi	70.36	6.00e-143	501.00
IUUC-Eca-033828	Equus caballus	76.18	0.00e+00	1592.00
IUUC-Eeu-034604	Erinaceus europaeus	80.77	1.00e-120	427.00
IUUC-Fca-035907	Felis catus	76.01	0.00e+00	1620.00
IUUC-Fal-037389	Ficedula albicollis	78.69	0.00e+00	1691.00
IUUC-Fox-037788	Fusarium oxysporum	36.05	4.00e-87	316.00
IUUC-Fso-038088	Fusarium solani	35.04	8.00e-83	302.00
IUUC-Gmo-039254	Gadus morhua	74.30	0.00e+00	1383.00
IUUC-Ggr-039941	Gaeumannomyces graminis	34.32	2.00e-83	304.00
IUUC-Gga-040310	Gallus gallus	79.24	0.00e+00	1689.00
IUUC-Gac-042054	Gasterosteus aculeatus	82.70	0.00e+00	1531.00
IUUC-Gma-042836	Glycine max	35.75	2.00e-101	363.00
IUUC-Ggo-045031	Gorilla gorilla	77.01	0.00e+00	1642.00
IUUC-Hsa-045880	Homo sapiens	76.92	0.00e+00	1640.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	61.61	3.00e-139	488.00
IUUC-Kpa-049307	Komagataella pastoris	38.10	8.00e-67	248.00
IUUC-Lch-050403	Latimeria chalumnae	76.43	0.00e+00	1556.00
IUUC-Lpe-051428	Leersia perrieri	46.10	1.00e-96	348.00
IUUC-Loc-052218	Lepisosteus oculatus	83.56	0.00e+00	1776.00
IUUC-Lma-053096	Leptosphaeria maculans	38.23	9.00e-79	288.00
IUUC-Laf-054162	Loxodonta africana	73.84	0.00e+00	1381.00
IUUC-Mcc-055127	Macaca mulatta	76.64	0.00e+00	1636.00
IUUC-Meu-056187	Macropus eugenii	79.13	6.00e-101	362.00
IUUC-Mor-057021	Magnaporthe oryzae	33.22	1.00e-75	278.00
IUUC-Mpo-057570	Magnaporthe poae	36.60	3.00e-76	280.00
IUUC-Mtr-058154	Medicago truncatula	36.06	1.00e-105	378.00
IUUC-Mla-059124	Melampsora laricipopulina	46.91	4.00e-100	358.00
IUUC-Mga-059581	Meleagris gallopavo	79.17	0.00e+00	1682.00
IUUC-Mvi-060445	Microbotryum violaceum	38.51	8.00e-103	368.00
IUUC-Mmr-061360	Microcebus murinus	73.70	0.00e+00	1492.00
IUUC-Mdo-062194	Monodelphis domestica	74.91	0.00e+00	1656.00
IUUC-Mmu-064189	Mus musculus	77.01	0.00e+00	1631.00
IUUC-Mpu-066439	Mustela putorius furo	75.47	0.00e+00	1568.00
IUUC-Mlu-068228	Myotis lucifugus	74.56	0.00e+00	1576.00
IUUC-Nfi-068280	Neosartorya fischeri	39.79	5.00e-80	293.00
IUUC-Ncr-068869	Neurospora crassa	35.80	2.00e-82	300.00
IUUC-Nle-069687	Nomascus leucogenys	76.44	0.00e+00	1591.00
IUUC-Opr-070592	Ochotona princeps	90.50	7.00e-107	381.00
IUUC-Ont-071836	Oreochromis niloticus	90.12	0.00e+00	1899.00
IUUC-Oan-072800	Ornithorhynchus anatinus	77.58	0.00e+00	1676.00
IUUC-Ocu-074587	Oryctolagus cuniculus	77.47	0.00e+00	1650.00
IUUC-Ola-087209	Oryzias latipes	87.63	0.00e+00	1802.00
IUUC-Olu-087699	Ostreococcus lucimarinus	43.94	9.00e-89	320.00
IUUC-Oga-088776	Otolemur garnettii	73.87	0.00e+00	1506.00
IUUC-Oar-089441	Ovis aries	75.97	0.00e+00	1611.00
IUUC-Ptr-091273	Pan troglodytes	76.92	0.00e+00	1640.00
IUUC-Pan-091981	Papio anubis	76.82	0.00e+00	1637.00
IUUC-Psi-093203	Pelodiscus sinensis	77.51	0.00e+00	1446.00
IUUC-Pma-094738	Petromyzon marinus	64.05	0.00e+00	1283.00
IUUC-Pno-095132	Phaeosphaeria nodorum	30.31	8.00e-59	222.00
IUUC-Ppa-095682	Physcomitrella patens	34.68	6.00e-113	402.00
IUUC-Pfo-097511	Poecilia formosa	89.45	0.00e+00	1894.00
IUUC-Pab-098634	Pongo abelii	74.35	0.00e+00	1567.00
IUUC-Pop-098928	Populus trichocarpa	36.35	4.00e-100	359.00
IUUC-Pca-100987	Procavia capensis	90.08	0.00e+00	734.00
IUUC-Pva-103034	Pteropus vampyrus	72.56	0.00e+00	1496.00
IUUC-Pgr-103513	Puccinia graminis	39.09	7.00e-106	379.00
IUUC-Ptt-103967	Puccinia triticina	40.60	1.00e-92	335.00
IUUC-Pte-104105	Pyrenophora teres	34.84	2.00e-79	291.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	37.88	8.00e-77	282.00
IUUC-Rno-105380	Rattus norvegicus	76.51	0.00e+00	1422.00
IUUC-Sce-106446	Saccharomyces cerevisiae	41.01	2.00e-67	250.00
IUUC-Sha-107108	Sarcophilus harrisii	71.42	0.00e+00	1506.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	45.39	1.00e-98	354.00
IUUC-Spo-108097	Schizosaccharomyces pombe	44.85	6.00e-95	342.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	30.27	3.00e-80	293.00
IUUC-Sly-111362	Solanum lycopersicum	35.99	2.00e-102	367.00
IUUC-Sar-113687	Sorex araneus	73.54	0.00e+00	813.00
IUUC-Sre-115038	Sporisorium reilianum	45.57	1.00e-101	365.00
IUUC-Ssc-115378	Sus scrofa	88.77	0.00e+00	701.00
IUUC-Tgu-116729	Taeniopygia guttata	78.25	0.00e+00	1675.00
IUUC-Tsy-118942	Tarsius syrichta	76.76	5.00e-168	585.00
IUUC-Tni-120732	Tetraodon nigroviridis	94.47	0.00e+00	1928.00
IUUC-Tca-121737	Theobroma cacao	36.31	5.00e-107	382.00
IUUC-Tre-121892	Trichoderma reesei	35.54	5.00e-85	309.00
IUUC-Tvi-122354	Trichoderma virens	34.38	7.00e-85	309.00
IUUC-Tme-127102	Tuber melanosporum	36.41	3.00e-93	337.00
IUUC-Tbe-127351	Tupaia belangeri	67.16	0.00e+00	1258.00
IUUC-Ttr-129061	Tursiops truncatus	73.62	0.00e+00	1556.00
IUUC-Uma-129343	Ustilago maydis	45.81	3.00e-103	370.00
IUUC-Vda-129748	Verticillium dahliae	37.86	1.00e-77	285.00
IUUC-Vvi-131234	Vitis vinifera	35.78	7.00e-103	369.00
IUUC-Xtr-132094	Xenopus tropicalis	77.53	0.00e+00	1607.00
IUUC-Xma-133923	Xiphophorus maculatus	89.55	0.00e+00	1892.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence